Advanced Search (OLGA)

Gene: Sertad1 (SERTA domain containing 1) Mus musculus

Analyze

Symbol:

Sertad1

Name:

SERTA domain containing 1

RGD ID:

1558246

MGI Page

MGI

Description:

Predicted to enable transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus and sarcoplasm. Is expressed in several structures, including 1st branchial arch; early embryo; genitourinary system; heart; and limb. Orthologous to human SERTAD1 (SERTA domain containing 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1110032C13Rik; AV000455; AW456625; CDK4-binding protein p34SEI1; p34SE; p34SEI-1; PHD zinc finger- and bromodomain-interacting protein 1; Sei; Sei-1; Sei1; SERTA domain-containing protein 1; transcriptional regulator interacting with the PHD-bromodomain 1; Trip; TRIP-Br1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SERTAD1 (SERTA domain containing 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SERTAD1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sertad1 (SERTA domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SERTAD1 (SERTA domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Sertad1 (SERTA domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:113340	Alliance	DIOPT (ZFIN)
Xenopus tropicalis (tropical clawed frog):	sertad1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	27,186,378 - 27,189,741 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	27,186,335 - 27,189,741 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	27,486,953 - 27,490,316 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	27,486,910 - 27,490,316 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	28,271,972 - 28,275,333 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	27,195,713 - 27,199,074 (+)	NCBI		MGSCv36	mm8
Celera	7	22,069,329 - 22,072,690 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	15.91	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Carpenter Syndrome 2 (ISO)

Colonic Neoplasms (ISO)

congenital hypoplastic anemia (ISO)

craniosynostosis 1 (ISO)

Diamond-Blackfan anemia (ISO)

maple syrup urine disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (EXP)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amphetamine (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

azathioprine (ISO)

benzene (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (EXP)

beta-lapachone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (ISO)

bisphenol F (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chloropicrin (ISO)

chlorpyrifos (EXP)

cidofovir anhydrous (ISO)

ciguatoxin CTX1B (EXP)

cisplatin (ISO)

clodronic acid (ISO)

cocaine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

diethyl malate (ISO)

diethyl maleate (ISO)

dioxygen (EXP,ISO)

disulfiram (ISO)

dorsomorphin (ISO)

ethanol (EXP)

ethyl methanesulfonate (ISO)

fenofibrate (ISO)

fenpyroximate (ISO)

fipronil (ISO)

flutamide (ISO)

folic acid (EXP,ISO)

formaldehyde (ISO)

gentamycin (ISO)

ifosfamide (ISO)

indometacin (ISO)

irinotecan (ISO)

Licochalcone B (ISO)

metformin (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

Nutlin-3 (ISO)

ochratoxin A (ISO)

orphenadrine (ISO)

oxaliplatin (ISO)

ozone (EXP,ISO)

p-chloromercuribenzoic acid (ISO)

pamidronate (ISO)

paracetamol (EXP,ISO)

pentanal (ISO)

phenobarbital (EXP)

picoxystrobin (ISO)

pirinixic acid (EXP)

potassium bromate (ISO)

potassium chromate (ISO)

pyrimidifen (ISO)

quercetin (ISO)

quercitrin (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

SB 431542 (ISO)

SCH 23390 (ISO)

silicon dioxide (EXP)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (ISO)

sunitinib (ISO)

tebufenpyrad (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thapsigargin (ISO)

thioacetamide (ISO)

thiram (ISO)

titanium dioxide (EXP)

topotecan (ISO)

triphenyl phosphate (ISO)

troglitazone (EXP)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell growth (ISO)

positive regulation of DNA-templated transcription (IDA)

positive regulation of transcription by RNA polymerase II (IGI)

Cellular Component

cytoplasm (IBA,ISO)

nucleus (IBA,IDA,ISO)

sarcoplasm (IDA)

Molecular Function

protein binding (IPI)

transcription coactivator activity (IBA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased insulin secretion (IAGP)

decreased pancreatic beta cell mass (IAGP)

decreased pancreatic islet number (IAGP)

impaired glucose tolerance (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	MGDs mouse GO annotations	MGD data from the GO Consortium
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11331592	PMID:12477932	PMID:12904583	PMID:14610273	PMID:15489334	PMID:16098148	PMID:16141072	PMID:16141073
PMID:16602821	PMID:18287559	PMID:18799693	PMID:20059953	PMID:20090907	PMID:20211142	PMID:20237268	PMID:21677750	PMID:21873635	PMID:22988430	PMID:24211589	PMID:27065194
PMID:27494853	PMID:28656888	PMID:29497033	PMID:31000741	PMID:35710446	PMID:35813469	PMID:38341852

Genomics

Comparative Map Data

Sertad1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	27,186,378 - 27,189,741 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	27,186,335 - 27,189,741 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	27,486,953 - 27,490,316 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	27,486,910 - 27,490,316 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	28,271,972 - 28,275,333 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	27,195,713 - 27,199,074 (+)	NCBI		MGSCv36	mm8
Celera	7	22,069,329 - 22,072,690 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	15.91	NCBI

SERTAD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	40,421,589 - 40,425,992 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	40,421,589 - 40,425,992 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	40,927,496 - 40,931,899 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	45,620,248 - 45,623,772 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	45,620,256 - 45,623,738	NCBI
Celera	19	37,727,962 - 37,731,486 (-)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	37,363,411 - 37,366,935 (-)	NCBI		HuRef
CHM1_1	19	40,928,060 - 40,931,584 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	43,242,229 - 43,246,633 (-)	NCBI		T2T-CHM13v2.0

Sertad1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	91,903,297 - 91,906,565 (+)	NCBI		GRCr8
mRatBN7.2	1	82,775,692 - 82,778,961 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	82,775,252 - 82,779,091 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	88,178,575 - 88,181,840 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	96,665,649 - 96,668,920 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	89,934,440 - 89,937,705 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	84,293,102 - 84,296,370 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	84,293,102 - 84,296,367 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	85,510,198 - 85,513,466 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	82,565,982 - 82,569,250 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	77,190,476 - 77,193,744 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Sertad1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955578	848,486 - 852,557 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955578	848,920 - 852,193 (+)	NCBI	ChiLan1.0	ChiLan1.0

SERTAD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	46,685,563 - 46,689,085 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	48,556,224 - 48,559,746 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	37,471,006 - 37,474,528 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	45,981,064 - 45,984,554 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

SERTAD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	113,270,199 - 113,273,112 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	113,272,051 - 113,272,764 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	112,672,133 - 112,675,051 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	113,868,553 - 113,871,471 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	113,868,588 - 113,871,465 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	113,427,849 - 113,430,769 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	113,060,334 - 113,063,252 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	114,054,300 - 114,057,219 (+)	NCBI		UU_Cfam_GSD_1.0

Sertad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	14,364,432 - 14,366,054 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	2,792,850 - 2,793,590 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	2,792,501 - 2,793,901 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SERTAD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	48,698,849 - 48,702,400 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	48,698,881 - 48,702,448 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	44,447,205 - 44,450,392 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SERTAD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	34,878,783 - 34,882,548 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	34,879,118 - 34,879,834 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	12,975,982 - 12,979,752 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sertad1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624925	414,158 - 417,570 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624925	414,158 - 417,592 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sertad1
154 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	365
Count of miRNA genes:	271
Interacting mature miRNAs:	304
Transcripts:	ENSMUST00000008528, ENSMUST00000135881
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300722	Sle3_m	systemic lupus erythmatosus susceptibility 3 (mouse)			Not determined		7	3511728	87142720	Mouse
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6502999	133501729	Mouse
4141566	Femwf8_m	femur work to failure 8 (mouse)			Not determined			13032485	47032621	Mouse
1301041	Prnr2_m	prion resistance 2 (mouse)			Not determined		7	18728794	39674033	Mouse
12904742	Litsq2_m	litter size QTL 2 (mouse)					7	22673887	56674033	Mouse
1301969	Lbw5_m	lupus NZB x NZW 5 (mouse)			Not determined		7	26847615	60851775	Mouse
1301622	Eae12_m	susceptibility to experimental allergic encephalomyelitis 12 (mouse)			Not determined		7	19280015	53280104	Mouse
11354952	Pdcc1_m	plasmacytoid dentritic cell compartment 1 (mouse)					7	23066531	57066531	Mouse
38501068	Tip1_m	tuberculosis immunophenotype 1, spleen CFU (mouse)					7	3602999	72549748	Mouse
25314314	Sccor1_m	synaptonemal complex length to mean MLH1 count ratio 1 (mouse)					7	13333925	47349748	Mouse
10449139	Eosn1_m	eosinophil differential 1 (mouse)					7	12480877	46480877	Mouse
1301052	Bhr6_m	bronchial hyperresponsiveness 6 (mouse)			Not determined		7	19842250	53842367	Mouse
11522751	Cocia17_m	cocaine-induced activity, QTL 17 (mouse)					7	13135204	47135204	Mouse
12792978	Fbmd3_m	femoral bone mineral density 3, females only (mouse)					7	7050288	142367832	Mouse
1301158	Eae4_m	susceptibility to experimental allergic encephalomyelitis 4 (mouse)			Not determined		7	19147398	141919804	Mouse
1301572	Sluc30_m	susceptibility to lung cancer 30 (mouse)			Not determined		7	2431696	36431844	Mouse
1357699	Nhdlq6_m	non-HDL QTL 6 (mouse)			Not determined		7	9988867	43988984	Mouse
10449158	Eosn3_m	eosinophil differential 3 (mouse)					7	12480877	46480877	Mouse
10412199	Sst2_m	susceptibility to tuberculosis 2 (mouse)			Not determined		7	18728794	119485380	Mouse
1558893	Spir1_m	Streptococcus pneumoniae infection resistance 1 (mouse)			Not determined		7	10305798	44305936	Mouse
1301709	Bdt4_m	bone density traits 4 (mouse)			Not determined		7	22888572	56888716	Mouse
1559016	Drsi_m	DCC-related Spp1 induction (mouse)			Not determined		7	16637293	49159331	Mouse

Markers in Region

AV000455

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	27,490,130 - 27,490,248	UniSTS	GRCm38
MGSCv37	7	28,275,149 - 28,275,267	UniSTS	GRCm37
Celera	7	22,072,506 - 22,072,624	UniSTS
Cytogenetic Map	7	A3	UniSTS
Whitehead/MRC_RH	7	336.31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001418519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_018820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC158304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF218291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF366400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF366401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK008303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC016077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000008528 ⟹ ENSMUSP00000008528

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	27,186,335 - 27,189,741 (+)	Ensembl
GRCm38.p6 Ensembl	7	27,486,910 - 27,490,316 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000135881 ⟹ ENSMUSP00000119180

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	27,186,800 - 27,188,932 (+)	Ensembl
GRCm38.p6 Ensembl	7	27,487,375 - 27,489,507 (+)	Ensembl

RefSeq Acc Id:

NM_001418519 ⟹ NP_001405448

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	27,186,758 - 27,189,741 (+)	NCBI

RefSeq Acc Id:

NM_018820 ⟹ NP_061290

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	27,186,378 - 27,189,741 (+)	NCBI
GRCm38	7	27,486,953 - 27,490,314 (+)	NCBI
MGSCv37	7	28,271,972 - 28,275,333 (+)	RGD
Celera	7	22,069,329 - 22,072,690 (+)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

AGAACTGCGCCTACCGTCCCAGGTGTCGGTTGCTGGAGCAGAACAAGCTAGCGATGCTACGGCA
GCCGCTTCCTGATTGGCTGCGTGTGGCTCCCTCTTCGTTCTGATTGGCCGCGAGTGATCTGTAG
GATGCTGAGCAAAGGTCTGAAGCGCAAGCGGGAGGAGGAGGAGACGATGGAAGCCCTCTCCGTG
GACTCGTGCTGGTTGGATCCGAGCCACCCGGCAGTGGCGCAGACCCCGCCGACGGTGGCTTCTA
GCTCCCTCTTTGACCTCTCAGTGGTCAAGCTCCACCACAGCCTGCGGCAGAGCGAGCCGGACCT
CCGGCACCTGGTGCTTGTGGTGAACACACTGAGGCGCATCCAGGCGTCCATGGAACCCGCACCT
GTCCTGCCGCCTGAGCCCATCCAGCCCCCAGCCCCTTCTGTGGCAGACAGCCTTCTGGCTAGCT
CAGATGCTGGCCTCTCAGCCTCCATGGCCAGCCTCCTGGAAGATCTCAACCACATTGAGGACCT
GAACCAGGCCCCCCAACCCCAAGCAGATGAGGGGCCTCCAGGCCGCTCCATCGGGGGGATCTCA
CCCAACCTGGGTGCCTTGGACTTGCTAGGCCCAGCCACTGGCTGTCTGCTGGACGATGGACTGG
AGGGCCTGTTTGAGGACATCGATACCTCCATGTACGACAGTGAACTTTGGTTACCAGCCTCTGA
GGGTCTCAAGCCCGGCCCTGAGAATGGCCCAGCCAAGGAGGAGCCTCCAGAGTTGGATGAGGCG
GAGTTGGACTACCTCATGGATGTACTAGTAGGCACACAGGCACTGGAAAGGCCACCAGGGCCTG
GGCGCTGACCCTTAGGACCCAGGGAGAATTGACTTGGATCTGAGTTGAGCCTGGTGGTGACACC
AACCCACTTTGACACGACACAGGTGGCGTCCCCTCACAGAGGAGAGCCAGGGTCACTTTGGAGA
GACTGTACTGAGTCCTGGGAACTTCACATCCATCCACCTGTCTTGACCAGTGAAGGAGTTGGAA
ATGAGCCCCGAGTGGTGAAATGACAGGGCCCAGTGACAGTAATGGTGTTTGGGCCAGGCTGGGG
TTGAACTGGGATAATAGTTTGGGCTATCCCATCCCATTATCCCCAGTGTGGGAAGAGACCTCAT
AATTTTTTGAAATTAAAACCAGCTTTGGGAAATACC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001405448	(Get FASTA)	NCBI Sequence Viewer
	NP_061290	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF27653	(Get FASTA)	NCBI Sequence Viewer
	AAH16077	(Get FASTA)	NCBI Sequence Viewer
	AAK52829	(Get FASTA)	NCBI Sequence Viewer
	AAK52830	(Get FASTA)	NCBI Sequence Viewer
	BAB22013	(Get FASTA)	NCBI Sequence Viewer
	BAB23130	(Get FASTA)	NCBI Sequence Viewer
	BAB25588	(Get FASTA)	NCBI Sequence Viewer
	EDL24184	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000008528
	ENSMUSP00000008528.8
	ENSMUSP00000119180.2
GenBank Protein	Q9JL10	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_061290 ⟸ NM_018820

- UniProtKB:

Q9D888 (UniProtKB/Swiss-Prot), Q925E6 (UniProtKB/Swiss-Prot), Q9JL10 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MLSKGLKRKREEEETMEALSVDSCWLDPSHPAVAQTPPTVASSSLFDLSVVKLHHSLRQSEPDL
RHLVLVVNTLRRIQASMEPAPVLPPEPIQPPAPSVADSLLASSDAGLSASMASLLEDLNHIEDL
NQAPQPQADEGPPGRSIGGISPNLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDSELWLPASE
GLKPGPENGPAKEEPPELDEAELDYLMDVLVGTQALERPPGPGR

hide sequence

Ensembl Acc Id:

ENSMUSP00000008528 ⟸ ENSMUST00000008528

Ensembl Acc Id:

ENSMUSP00000119180 ⟸ ENSMUST00000135881

RefSeq Acc Id:	NP_001405448 ⟸ NM_001418519
- UniProtKB:	Q9JL10 (UniProtKB/Swiss-Prot), Q9D888 (UniProtKB/Swiss-Prot), Q925E6 (UniProtKB/Swiss-Prot)

Protein Domains

SERTA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JL10-F1-model_v2	AlphaFold	Q9JL10	1-236	view protein structure

Promoters

RGD ID:

6892376

Promoter ID:

EPDNEW_M9639

Type:

multiple initiation site

Name:

Sertad1_1

Description:

Mus musculus SERTA domain containing 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	27,486,953 - 27,487,013	EPDNEW

RGD ID:

6842005

Promoter ID:

MM_KWN:49557

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000058623, OTTMUST00000058624

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	7	28,271,031 - 28,272,062 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1913438	AgrOrtholog
Ensembl Genes	ENSMUSG00000008384	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000008528	ENTREZGENE
	ENSMUST00000008528.8	UniProtKB/Swiss-Prot
	ENSMUST00000135881.2	UniProtKB/TrEMBL
InterPro	E2F-SERTA_domain_protein	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERTA_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:55942	UniProtKB/Swiss-Prot
MGD	MGI:1913438	ENTREZGENE
NCBI Gene	Sertad1	ENTREZGENE
PANTHER	CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERTA DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	SERTA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Sertad1	PhenoGen
PROSITE	SERTA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	D3Z2X7_MOUSE	UniProtKB/TrEMBL
	Q925E6	ENTREZGENE
	Q9D888	ENTREZGENE
	Q9DCZ2_MOUSE	UniProtKB/TrEMBL
	Q9JL10	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q925E6	UniProtKB/Swiss-Prot
	Q9D888	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Sertad1	SERTA domain containing 1	1110032C13Rik	RIKEN cDNA 1110032C13 gene	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	1110032C13Rik	RIKEN cDNA 1110032C13 gene	Sertad1	SERTA domain containing 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype