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Gene: Casp2 (caspase 2) Mus musculus
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Symbol: Casp2
Name: caspase 2
Description: Exhibits cysteine-type endopeptidase activity involved in apoptotic process. Involved in ectopic germ cell programmed cell death; extrinsic apoptotic signaling pathway in absence of ligand; and positive regulation of apoptotic signaling pathway. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CASP2 (caspase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CASP-2; Caspase-2; ICH-1; NEDD-2; Nedd2; neural precursor cell expressed developmentally down-regulated protein 2; protease ICH-1
Orthologs:
Homo sapiens (human) : CASP2 (caspase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp2 (caspase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp2 (caspase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP2 (caspase 2)
Canis lupus familiaris (dog) : CASP2 (caspase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp2 (caspase 2)
Sus scrofa (pig) : CASP2 (caspase 2)
Chlorocebus sabaeus (African green monkey) : CASP2 (caspase 2)
Heterocephalus glaber (naked mole-rat) : Casp2 (caspase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl642,264,985 - 42,282,508 (+)EnsemblGRCm38mm10GRCm38
GRCm38642,264,902 - 42,282,508 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37642,215,038 - 42,232,495 (+)NCBIGRCm37mm9NCBIm37
MGSCv36642,194,646 - 42,212,103 (+)NCBImm8
Celera642,209,337 - 42,226,794 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Casp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731460
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.