Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a) - Rat Genome Database

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Gene: Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a) Mus musculus
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Symbol: Tnfrsf1a
Name: tumor necrosis factor receptor superfamily, member 1a
RGD ID: 734247
MGI Page MGI
Description: Exhibits tumor necrosis factor-activated receptor activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of extracellular matrix constituent secretion; and semi-lunar valve development. Localizes to cell surface and membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; lung; and reproductive system. Used to study autosomal dominant familial periodic fever. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; acne; allergic bronchopulmonary aspergillosis; autoimmune disease (multiple); and autosomal dominant familial periodic fever. Orthologous to human TNFRSF1A (TNF receptor superfamily member 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD120; CD120a; FPF; p5; p55; p55-R; p60; TN; Tnf; TNF receptor alpha chain; TNF-; TNF-a; TNF-alpha-R1; TNF-alphaR1; TNF-R; TNF-R-I; TNF-R1; TNF-R55; TNF-RI; TNFal; TNFalpha-R1; TNFAR; TNFR; Tnfr-2; TNFR-I; Tnfr1; TNFR60; TNFRI; TNFRp55; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type I
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,326,686 - 125,339,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl6125,326,325 - 125,339,447 (+)Ensembl
GRCm386125,349,723 - 125,362,483 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,349,362 - 125,362,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,299,741 - 125,312,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv366125,315,374 - 125,328,104 (+)NCBImm8
Celera6127,020,792 - 127,033,747 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acne  (ISO)
acquired immunodeficiency syndrome  (ISO)
acute kidney failure  (IMP,ISO)
adult respiratory distress syndrome  (IEP,IMP,ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic disease  (ISO)
Alzheimer's disease  (IMP,ISO)
amyloidosis  (ISO)
anemia  (ISO)
Anorexia  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
arteriosclerosis  (IAGP)
asthma  (IEP)
autoimmune disease  (ISO)
autosomal dominant familial periodic fever  (IEA,ISO)
autosomal recessive pseudohypoaldosteronism type 1  (ISO)
bacterial pneumonia  (IEP)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
bronchiectasis  (ISO)
Cachexia  (ISO)
CHARGE syndrome  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon carcinoma  (IEP)
colorectal adenoma  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Crohn's disease  (ISO)
cryptogenic organizing pneumonia  (ISO)
cystic fibrosis  (ISO)
cytomegalovirus retinitis  (IMP)
Diabetic Nephropathies  (ISO)
End Stage Liver Disease  (ISO)
end stage renal disease  (ISO)
endometrial cancer  (ISO)
Enterovirus Infections  (IMP)
Experimental Arthritis  (IMP,ISO)
Experimental Autoimmune Uveoretinitis  (IMP)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Pancreatitis, Acute  (ISO)
extrinsic allergic alveolitis  (ISO)
familial Mediterranean fever  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
fibrosarcoma  (ISO)
focal segmental glomerulosclerosis  (IEP)
genetic disease  (ISO)
glomerulonephritis  (ISO)
Human Influenza  (IMP,ISO)
Hyperalgesia  (IMP,ISO)
Hyperoxia  (ISO)
Hyperphosphatemic Familial Tumoral Calcinosis 1  (ISO)
IgA glomerulonephritis  (ISO)
Insulin Resistance  (ISO)
ischemia  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (IEP)
Legionnaires' disease  (IMP)
Liver Reperfusion Injury  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (IGI,ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (ISO)
Muscle Weakness  (IMP)
myocardial infarction  (ISO)
Nasal Polyps  (ISO)
Nematode Infections  (ISO)
Neurogenic Inflammation  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
Optic Nerve Injuries  (IMP,ISO)
ovarian cancer  (ISO)
Pain  (ISO)
peroxisome biogenesis disorder 2B  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
primary biliary cholangitis  (ISO)
Pseudomonas Infections  (IMP)
psoriasis  (ISO)
Radiation Pneumonitis  (IMP)
renal cell carcinoma  (ISO)
renal fibrosis  (IMP)
Reperfusion Injury  (ISO)
retinal detachment  (IMP)
rheumatoid arthritis  (ISO)
root resorption  (ISO)
sciatic neuropathy  (IMP,ISO)
silicosis  (IMP)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (IMP)
systemic lupus erythematosus  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
uveitis  (ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-colchicine  (EXP)
(S)-nicotine  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-methylcholine  (ISO)
2-naphthylamine  (ISO)
3,3'-diindolylmethane  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-tert-butylphenol  (ISO)
5-aza-2'-deoxycytidine  (EXP)
[des-Arg(9)]-bradykinin  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
AH23848  (ISO)
AICA ribonucleotide  (EXP)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
Aloe emodin  (ISO)
alpha-pinene  (ISO)
aminoguanidine  (EXP)
amphetamine  (ISO)
amphibole asbestos  (ISO)
antirheumatic drug  (ISO)
arachidonic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
asperentin  (EXP)
atorvastatin calcium  (ISO)
azathioprine  (ISO)
Bandrowski's base  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
boric acid  (EXP)
butylated hydroxyanisole  (EXP)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
capsaicin  (EXP,ISO)
capsazepine  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
cefaloridine  (ISO)
chloroform  (ISO)
chloroquine  (EXP)
cholesterol  (ISO)
cisplatin  (EXP)
clobetasol  (EXP)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP,ISO)
dieldrin  (ISO)
dihydroxyacetone  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (ISO)
dioscin  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (EXP)
fenamidone  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fumonisin B1  (EXP)
furosemide  (ISO)
gadolinium trichloride  (EXP)
genistein  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexachlorobenzene  (ISO)
hydrogen peroxide  (EXP,ISO)
indometacin  (EXP,ISO)
irinotecan  (ISO)
isoflurane  (ISO)
isoprenaline  (ISO)
ketoconazole  (EXP)
L-mimosine  (ISO)
lead nitrate  (EXP)
leflunomide  (ISO)
lenalidomide  (ISO)
lignan  (ISO)
lipopolysaccharide  (EXP,ISO)
magnesium atom  (ISO)
magnesium oxide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methacholine chloride  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
mifepristone  (ISO)
Mitotane  (ISO)
monodansylcadaverine  (EXP)
motexafin gadolinium  (ISO)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naloxone  (ISO)
nefazodone  (ISO)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitrates  (ISO)
Nonidet P-40  (ISO)
notoginsenoside R1  (EXP)
o-anisidine  (ISO)
ochratoxin A  (ISO)
octreotide  (ISO)
osthole  (ISO)
ozone  (EXP,ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentobarbital  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphoramide mustard  (ISO)
prochloraz  (ISO)
progesterone  (EXP,ISO)
propylparaben  (ISO)
prostaglandin E2  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quercitrin  (ISO)
quinidine  (ISO)
resiniferatoxin  (EXP)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
SB 203580  (EXP)
selenium atom  (ISO)
serpentine asbestos  (EXP)
sesquiterpene  (ISO)
simvastatin  (EXP)
sodium arsenite  (EXP,ISO)
sodium stibogluconate  (ISO)
Soman  (ISO)
sterigmatocystin  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thalidomide  (ISO)
titanium dioxide  (EXP,ISO)
tolcapone  (ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimethyltin  (EXP)
triptonide  (EXP)
valdecoxib  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
WR-1065  (EXP)
zerumbone  (ISO)
zinc acetate  (ISO)
zinc atom  (EXP,ISO)
zinc molecular entity  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve development  (IGI)
apoptotic process  (IEA)
cell surface receptor signaling pathway  (IMP)
cellular response to estradiol stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
cytokine-mediated signaling pathway  (IMP)
defense response  (IMP)
defense response to bacterium  (IMP)
inflammatory response  (IBA,IMP,ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IMP)
negative regulation of apoptotic process  (ISO)
negative regulation of cardiac muscle hypertrophy  (IGI)
negative regulation of extracellular matrix constituent secretion  (IGI)
negative regulation of gene expression  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-6 production  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of apoptotic process involved in morphogenesis  (IGI)
positive regulation of gene expression  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of inflammatory response  (IMP)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (IMP,ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
prostaglandin metabolic process  (TAS)
protein localization to plasma membrane  (ISO)
pulmonary valve development  (IGI)
regulation of apoptotic process  (ISO)
regulation of establishment of endothelial barrier  (ISO)
response to alkaloid  (ISO)
response to amino acid  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to wounding  (ISO)
signal transduction  (IEA)
tumor necrosis factor-mediated signaling pathway  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue morphology  (IAGP)
abnormal airway responsiveness  (IAGP)
abnormal body temperature homeostasis  (IAGP)
abnormal bone healing  (IAGP)
abnormal brain wave pattern  (IAGP)
abnormal chemokine level  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal circadian temperature homeostasis  (IAGP)
abnormal corneal epithelium morphology  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal eye development  (IAGP)
abnormal follicular dendritic cell morphology  (IAGP)
abnormal glial cell physiology  (IAGP)
abnormal glutamate-mediated receptor currents  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal intestine physiology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal liver regeneration  (IAGP)
abnormal lymph node B cell domain morphology  (IAGP)
abnormal lymph node cortex morphology  (IAGP)
abnormal lymph node primary follicle morphology  (IAGP)
abnormal lymph node secondary follicle morphology  (IAGP)
abnormal lymph organ development  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal metabolism  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal neuron proliferation  (IAGP)
abnormal oval cell physiology  (IAGP)
abnormal pancreatic islet morphology  (IAGP)
abnormal Peyer's patch follicle morphology  (IAGP)
abnormal Peyer's patch morphology  (IAGP)
abnormal respiratory mechanics  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal retinal blood vessel morphology  (IAGP)
abnormal sleep pattern  (IAGP)
abnormal spleen germinal center morphology  (IAGP)
abnormal thrombosis  (IAGP)
abnormal thymus morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vascular development  (IAGP)
absent follicular dendritic cells  (IAGP)
absent lymph node germinal center  (IAGP)
absent spleen germinal center  (IAGP)
amyloid beta deposits  (IAGP)
anemia  (IAGP)
arthritis  (IAGP)
blindness  (IAGP)
broad limb buds  (IAGP)
cachexia  (IAGP)
cerebral amyloid angiopathy  (IAGP)
corneal vascularization  (IAGP)
curly tail  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased circulating alanine transaminase level  (IAGP)
decreased circulating calcium level  (IEA)
decreased circulating insulin level  (IAGP)
decreased circulating interleukin-1 beta level  (IAGP)
decreased circulating interleukin-6 level  (IAGP)
decreased circulating total protein level  (IEA)
decreased cornea thickness  (IAGP)
decreased food intake  (IAGP)
decreased hemoglobin content  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased inflammatory response  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased microglial cell activation  (IAGP)
decreased microglial cell number  (IAGP)
decreased monocyte cell number  (IEA)
decreased neutrophil cell number  (IEA)
decreased Peyer's patch number  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased red blood cell distribution width  (IEA)
decreased sensitivity to induced morbidity/mortality  (IAGP)
decreased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
decreased spleen weight  (IEA)
decreased spleen white pulp amount  (IAGP)
decreased susceptibility to autoimmune diabetes  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to Coronaviridae infection  (IAGP)
decreased susceptibility to dopaminergic neuron neurotoxicity  (IAGP)
decreased susceptibility to endotoxin shock  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to experimental autoimmune uveoretinitis  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased susceptibility to induced colitis  (IAGP)
decreased tumor incidence  (IAGP)
demyelination  (IAGP)
dental pulp necrosis  (IAGP)
dilated vasculature  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IAGP)
epidermal hyperplasia  (IAGP)
extramedullary hematopoiesis  (IAGP)
focal hepatic necrosis  (IAGP)
glomerulonephritis  (IAGP)
granulomatous inflammation  (IAGP)
heart inflammation  (IAGP)
hepatic steatosis  (IAGP)
impaired adaptive thermogenesis  (IAGP)
impaired central nervous system regeneration  (IAGP)
impaired humoral immune response  (IAGP)
impaired neutrophil recruitment  (IAGP)
impaired skeletal muscle regeneration  (IAGP)
impaired skin barrier function  (IAGP)
increased basophil cell number  (IEA)
increased bone mineral density  (IAGP)
increased bone resorption  (IAGP)
increased cerebral infarction size  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating aspartate transaminase level  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating lactate dehydrogenase level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased corneal epithelium thickness  (IAGP)
increased eosinophil cell number  (IAGP)
increased incidence of corneal inflammation  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased large unstained cell number  (IEA)
increased leukocyte cell number  (IAGP)
increased lymphocyte cell number  (IAGP)
increased myocardial infarction size  (IAGP)
increased neutrophil cell number  (IAGP)
increased sensitivity to induced cell death  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased skin papilloma incidence  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
increased susceptibility to fungal infection  (IAGP)
increased susceptibility to induced colitis  (IAGP)
increased susceptibility to neuronal excitotoxicity  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased susceptibility to type I hypersensitivity reaction  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
interstitial pneumonia  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
liver fibrosis  (IAGP)
liver inflammation  (IAGP)
lung inflammation  (IAGP)
macrovesicular hepatic steatosis  (IAGP)
microgliosis  (IAGP)
microvesicular hepatic steatosis  (IAGP)
open neural tube  (IAGP)
osteomyelitis  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
pulmonary fibrosis  (IAGP)
renal interstitial fibrosis  (IAGP)
seizures  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
small intestinal inflammation  (IAGP)
small Peyer's patches  (IAGP)
spleen hyperplasia  (IAGP)
thick epidermis  (IAGP)
tumor regression  (IAGP)
References

References - curated
1. Aderka D, etal., Arthritis Rheum. 1993 Aug;36(8):1111-20.
2. Aderka D, etal., Cancer Res. 1991 Oct 15;51(20):5602-7.
3. Agudo M, etal., Mol Vis. 2008 Jun 3;14:1050-63.
4. Arntz OJ, etal., Arthritis Res Ther. 2010;12(2):R61. doi: 10.1186/ar2974. Epub 2010 Apr 6.
5. Aten J, etal., J Am Soc Nephrol. 2000 Aug;11(8):1426-38.
6. Bao C, etal., Biochem Cell Biol. 2010 Aug;88(4):629-34.
7. Bao CH, etal., Dig Dis Sci. 2012 Sep;57(9):2286-95. doi: 10.1007/s10620-012-2161-0. Epub 2012 Apr 25.
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PMID:17242061   PMID:17242187   PMID:17261656   PMID:17264149   PMID:17266397   PMID:17277132   PMID:17279553   PMID:17283089   PMID:17328072   PMID:17328785   PMID:17353199   PMID:17361131  
PMID:17404289   PMID:17404323   PMID:17405815   PMID:17409152   PMID:17416608   PMID:17428547   PMID:17431131   PMID:17435079   PMID:17438146   PMID:17464333   PMID:17467668   PMID:17483359  
PMID:17500068   PMID:17506816   PMID:17510296   PMID:17517872   PMID:17540734   PMID:17548650   PMID:17561271   PMID:17581950   PMID:17590392   PMID:17617585   PMID:17640882   PMID:17640973  
PMID:17641296   PMID:17673686   PMID:17682046   PMID:17692539   PMID:17692826   PMID:17702576   PMID:17703428   PMID:17762182   PMID:17851089   PMID:17884256   PMID:17923086   PMID:17925397  
PMID:17949991   PMID:17959902   PMID:17979156   PMID:17992258   PMID:18022363   PMID:18025217   PMID:18097003   PMID:18184798   PMID:18187611   PMID:18189316   PMID:18192488   PMID:18198209  
PMID:18219394   PMID:18242213   PMID:18250193   PMID:18250323   PMID:18286589   PMID:18308862   PMID:18329246   PMID:18337250   PMID:18373618   PMID:18382767   PMID:18385284   PMID:18390708  
PMID:18408078   PMID:18413601   PMID:18422761   PMID:18430733   PMID:18442881   PMID:18452158   PMID:18461160   PMID:18464930   PMID:18467504   PMID:18483211   PMID:18490660   PMID:18493257  
PMID:18505433   PMID:18515164   PMID:18535181   PMID:18538734   PMID:18544042   PMID:18549896   PMID:18559949   PMID:18562480   PMID:18566103   PMID:18606667   PMID:18606695   PMID:18612394  
PMID:18621737   PMID:18628255   PMID:18632856   PMID:18641654   PMID:18660426   PMID:18687977   PMID:18713739   PMID:18719121   PMID:18728678   PMID:18768889   PMID:18772111   PMID:18799693  
PMID:18805969   PMID:18815054   PMID:18824172   PMID:18824767   PMID:18825372   PMID:18830417   PMID:18841074   PMID:18926564   PMID:18931327   PMID:18940942   PMID:18941239   PMID:18948547  
PMID:19004989   PMID:19008338   PMID:19050279   PMID:19118019   PMID:19119026   PMID:19144778   PMID:19150425   PMID:19193879   PMID:19194472   PMID:19201879   PMID:19208810   PMID:19211506  
PMID:19228962   PMID:19234607   PMID:19246648   PMID:19255345   PMID:19278729   PMID:19285115   PMID:19289507   PMID:19303389   PMID:19323909   PMID:19380791   PMID:19388357   PMID:19403643  
PMID:19435851   PMID:19477937   PMID:19479048   PMID:19494115   PMID:19494310   PMID:19516260   PMID:19519169   PMID:19531269   PMID:19535637   PMID:19546478   PMID:19582157   PMID:19590497  
PMID:19608869   PMID:19625730   PMID:19626033   PMID:19641494   PMID:19648283   PMID:19681056   PMID:19720838   PMID:19741298   PMID:19759514   PMID:19772956   PMID:19783685   PMID:19788501  
PMID:19800575   PMID:19815541   PMID:19890995   PMID:19907077   PMID:19913791   PMID:19923470   PMID:19927158   PMID:19931338   PMID:19933155   PMID:19941340   PMID:19949106   PMID:20005846  
PMID:20035831   PMID:20042666   PMID:20056718   PMID:20080755   PMID:20093491   PMID:20145121   PMID:20146926   PMID:20156456   PMID:20160664   PMID:20212506   PMID:20226875   PMID:20233880  
PMID:20302876   PMID:20335614   PMID:20368698   PMID:20383154   PMID:20421368   PMID:20436484   PMID:20453108   PMID:20457915   PMID:20468050   PMID:20478363   PMID:20483718   PMID:20506490  
PMID:20519121   PMID:20530205   PMID:20534702   PMID:20566898   PMID:20628198   PMID:20646763   PMID:20685290   PMID:20713516   PMID:20739394   PMID:20810989   PMID:20826683   PMID:20855879  
PMID:20857415   PMID:20870942   PMID:20890285   PMID:20921405   PMID:20926563   PMID:20926808   PMID:21074606   PMID:21098094   PMID:21148330   PMID:21153132   PMID:21159431   PMID:21164518  
PMID:21187446   PMID:21266511   PMID:21267068   PMID:21268004   PMID:21278344   PMID:21278350   PMID:21282379   PMID:21307132   PMID:21320567   PMID:21378027   PMID:21383240   PMID:21393251  
PMID:21393509   PMID:21402942   PMID:21410936   PMID:21419662   PMID:21427409   PMID:21464320   PMID:21471444   PMID:21515659   PMID:21518864   PMID:21519143   PMID:21523796   PMID:21526210  
PMID:21602809   PMID:21603208   PMID:21621534   PMID:21626455   PMID:21641402   PMID:21653902   PMID:21658601   PMID:21668898   PMID:21670171   PMID:21677750   PMID:21709152   PMID:21734073  
PMID:21737776   PMID:21768269   PMID:21768400   PMID:21802165   PMID:21825016   PMID:21835156   PMID:21867719   PMID:21873635   PMID:21880915   PMID:21911709   PMID:21912643   PMID:21926986  
PMID:21930713   PMID:21957083   PMID:21982949   PMID:21987217   PMID:21989628   PMID:21989986   PMID:22000287   PMID:22011580   PMID:22016541   PMID:22052013   PMID:22075779   PMID:22075930  
PMID:22081022   PMID:22096246   PMID:22102723   PMID:22123964   PMID:22212899   PMID:22298528   PMID:22327219   PMID:22461450   PMID:22516259   PMID:22522614   PMID:22546736   PMID:22547679  
PMID:22561136   PMID:22561347   PMID:22570350   PMID:22572473   PMID:22576661   PMID:22578011   PMID:22615203   PMID:22666310   PMID:22675442   PMID:22685265   PMID:22687964   PMID:22698400  
PMID:22770220   PMID:22773667   PMID:22776139   PMID:22814289   PMID:22837196   PMID:22837383   PMID:22840842   PMID:22863009   PMID:22863952   PMID:22898814   PMID:22901753   PMID:22912582  
PMID:22933014   PMID:22972987   PMID:22982779   PMID:22984249   PMID:23029133   PMID:23064360   PMID:23071785   PMID:23154968   PMID:23222736   PMID:23226465   PMID:23277487   PMID:23285227  
PMID:23337087   PMID:23341629   PMID:23349631   PMID:23376950   PMID:23382219   PMID:23385062   PMID:23389459   PMID:23465561   PMID:23487422   PMID:23487424   PMID:23489296   PMID:23526821  
PMID:23584070   PMID:23602765   PMID:23611870   PMID:23619146   PMID:23623383   PMID:23639813   PMID:23651635   PMID:23657875   PMID:23676465   PMID:23704873   PMID:23708969   PMID:23717489  
PMID:23733314   PMID:23749144   PMID:23753529   PMID:23785004   PMID:23815148   PMID:23817200   PMID:23850678   PMID:23869211   PMID:23871670   PMID:23874808   PMID:23903370   PMID:23940256  
PMID:23966299   PMID:23975421   PMID:23977171   PMID:24002060   PMID:24036366   PMID:24046352   PMID:24062487   PMID:24089213   PMID:24098720   PMID:24100384   PMID:24122297   PMID:24133099  
PMID:24135018   PMID:24211183   PMID:24244024   PMID:24286726   PMID:24303082   PMID:24307739   PMID:24310780   PMID:24315369   PMID:24337380   PMID:24378531   PMID:24391492   PMID:24453255  
PMID:24453977   PMID:24461064   PMID:24469399   PMID:24520376   PMID:24531553   PMID:24535827   PMID:24549331   PMID:24557836   PMID:24566711   PMID:24569452   PMID:24587231   PMID:24587232  
PMID:24595131   PMID:24623132   PMID:24626175   PMID:24706750   PMID:24711449   PMID:24736233   PMID:24811380   PMID:24813849   PMID:24813850   PMID:24832470   PMID:24842373   PMID:24856420  
PMID:24865838   PMID:24892805   PMID:24892821   PMID:24913232   PMID:24938671   PMID:24947351   PMID:24960204   PMID:24971483   PMID:24980434   PMID:25005154   PMID:25049377   PMID:25132550  
PMID:25148914   PMID:25186904   PMID:25267645   PMID:25278099   PMID:25347747   PMID:25387791   PMID:25401743   PMID:25425265   PMID:25443631   PMID:25443632   PMID:25475856   PMID:25540015  
PMID:25552370   PMID:25569104   PMID:25608711   PMID:25628461   PMID:25729921   PMID:25807548   PMID:25815583   PMID:25848866   PMID:25909160   PMID:25911755   PMID:25934492   PMID:25934503  
PMID:25959608   PMID:25968334   PMID:25977337   PMID:25985180   PMID:25995337   PMID:26008898   PMID:26019295   PMID:26033565   PMID:26076811   PMID:26117714   PMID:26147686   PMID:26184908  
PMID:26189092   PMID:26190110   PMID:26195802   PMID:26224629   PMID:26245758   PMID:26246237   PMID:26268655   PMID:26270730   PMID:26291484   PMID:26352810   PMID:26365184   PMID:26386311  
PMID:26411367   PMID:26440518   PMID:26456334   PMID:26483205   PMID:26491108   PMID:26511769   PMID:26555174   PMID:26649818   PMID:26686654   PMID:26728651   PMID:26817517   PMID:26819253  
PMID:26835538   PMID:26846887   PMID:26892362   PMID:26931771   PMID:26964500   PMID:26973245   PMID:26976640   PMID:26982364   PMID:26991125   PMID:27013233   PMID:27018768   PMID:27021371  
PMID:27043414   PMID:27071119   PMID:27080468   PMID:27133471   PMID:27147664   PMID:27160902   PMID:27273552   PMID:27275091   PMID:27288458   PMID:27318131   PMID:27396959   PMID:27403737  
PMID:27411587   PMID:27435916   PMID:27456129   PMID:27475257   PMID:27526711   PMID:27555760   PMID:27556180   PMID:27560480   PMID:27591224   PMID:27601345   PMID:27612997   PMID:27663205  
PMID:27671548   PMID:27709293   PMID:27756058   PMID:27863204   PMID:27899821   PMID:27917412   PMID:27927647   PMID:27932454   PMID:27979472   PMID:27995986   PMID:28038359   PMID:28052249  
PMID:28062509   PMID:28092866   PMID:28120397   PMID:28123022   PMID:28161398   PMID:28161590   PMID:28287124   PMID:28330904   PMID:28345588   PMID:28365861   PMID:28379965   PMID:28385632  
PMID:28387756   PMID:28410990   PMID:28497109   PMID:28572508   PMID:28609656   PMID:28619762   PMID:28628031   PMID:28637784   PMID:28676525   PMID:28696292   PMID:28723569   PMID:28736159  
PMID:28747340   PMID:28758900   PMID:28797835   PMID:28875549   PMID:28890718   PMID:28898696   PMID:28912506   PMID:28920954   PMID:29040328   PMID:29057962   PMID:29081378   PMID:29113822  
PMID:29142275   PMID:29203883   PMID:29212904   PMID:29232557   PMID:29273790   PMID:29375132   PMID:29386201   PMID:29434332   PMID:29436413   PMID:29472246   PMID:29494692   PMID:29500178  
PMID:29596938   PMID:29618659   PMID:29630857   PMID:29661823   PMID:29695863   PMID:29795446   PMID:29800552   PMID:29802833   PMID:29860102   PMID:29891719   PMID:29903342   PMID:29969604  
PMID:29973541   PMID:30097537   PMID:30123776   PMID:30185824   PMID:30206205   PMID:30209212   PMID:30277599   PMID:30292879   PMID:30304732   PMID:30354252   PMID:30361263   PMID:30361383  
PMID:30420664   PMID:30457980   PMID:30463004   PMID:30586024   PMID:30598363   PMID:30631042   PMID:30635238   PMID:30639056   PMID:30731109   PMID:30820720   PMID:30862875   PMID:30894050  
PMID:30923339   PMID:30988397   PMID:31004466   PMID:31070761   PMID:31132747   PMID:31141691   PMID:31151047   PMID:31209376   PMID:31346084   PMID:31358656   PMID:31358823   PMID:31505254  
PMID:31511692   PMID:31519887   PMID:31759325   PMID:31787972   PMID:31872076   PMID:31875557   PMID:31919471   PMID:31959883   PMID:32004684   PMID:32075735   PMID:32075762   PMID:32094187  
PMID:32094226   PMID:32173863   PMID:32231246   PMID:32325033   PMID:32398258   PMID:32424282   PMID:32540999   PMID:32559293   PMID:32968282   PMID:32971525   PMID:33086075   PMID:33215740  
PMID:33270628   PMID:33303682   PMID:33311474   PMID:33397971  


Genomics

Comparative Map Data
Tnfrsf1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,326,686 - 125,339,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl6125,326,325 - 125,339,447 (+)Ensembl
GRCm386125,349,723 - 125,362,483 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,349,362 - 125,362,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,299,741 - 125,312,501 (+)NCBIGRCm37mm9NCBIm37
MGSCv366125,315,374 - 125,328,104 (+)NCBImm8
Celera6127,020,792 - 127,033,747 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.32NCBI
TNFRSF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl126,328,757 - 6,342,114 (-)EnsemblGRCh38hg38GRCh38
GRCh38126,328,771 - 6,342,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,437,937 - 6,451,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,308,184 - 6,321,522 (-)NCBINCBI36hg18NCBI36
Build 34126,308,184 - 6,321,522NCBI
Celera128,054,567 - 8,067,927 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,291,179 - 6,304,533 (-)NCBIHuRef
CHM1_1126,437,153 - 6,450,509 (-)NCBICHM1_1
Tnfrsf1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24158,150,815 - 158,163,592 (+)NCBI
Rnor_6.0 Ensembl4157,864,969 - 157,877,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04157,864,905 - 157,877,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,881,368 - 224,894,089 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,172,563 - 162,185,252 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14162,417,498 - 162,430,188 (+)NCBI
Celera4146,886,949 - 146,899,646 (+)NCBICelera
RH 3.4 Map41000.9RGD
Cytogenetic Map4q42NCBI
Tnfrsf1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554133,981,400 - 3,996,021 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554133,982,670 - 3,996,320 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,374,256 - 6,387,613 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,374,257 - 6,387,613 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,457,617 - 6,470,969 (-)NCBIMhudiblu_PPA_v0panPan3
TNFRSF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,641,837 - 38,654,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,638,753 - 38,700,282 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,959,778 - 7,972,628 (-)NCBI
ROS_Cfam_1.02738,997,951 - 39,010,819 (+)NCBI
UMICH_Zoey_3.12738,870,492 - 38,883,352 (+)NCBI
UNSW_CanFamBas_1.02738,911,954 - 38,924,837 (+)NCBI
UU_Cfam_GSD_1.0277,438,485 - 7,451,382 (-)NCBI
Tnfrsf1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,735,979 - 102,753,899 (+)NCBI
SpeTri2.0NW_0049367091,407,327 - 1,421,448 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl564,319,073 - 64,331,909 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1564,319,349 - 64,331,876 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,780,726 - 66,793,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF1A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,364,544 - 6,378,880 (-)NCBI
ChlSab1.1 Ensembl116,364,330 - 6,378,902 (-)Ensembl
Tnfrsf1a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248603,111,244 - 3,123,041 (-)NCBI

Position Markers
D6Mit254  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386125,356,646 - 125,356,785UniSTSGRCm38
MGSCv376125,306,664 - 125,306,803UniSTSGRCm37
Celera6127,027,922 - 127,028,039UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.55UniSTS
Whitehead Genetic649.2UniSTS
Whitehead_YAC6 UniSTS
PMC124385P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386125,361,845 - 125,362,072UniSTSGRCm38
MGSCv376125,311,863 - 125,312,090UniSTSGRCm37
Celera6127,033,108 - 127,033,335UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.55UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386125,361,828 - 125,362,215UniSTSGRCm38
MGSCv376125,311,846 - 125,312,233UniSTSGRCm37
Celera6127,033,091 - 127,033,479UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.55UniSTS
cM Map660.55UniSTS
cM Map475.5UniSTS
cM Map660.55UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6F3UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6F3UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384145,215,340 - 145,215,566UniSTSGRCm38
MGSCv374144,805,243 - 144,805,469UniSTSGRCm37
Celera4146,804,767 - 146,804,993UniSTS
Cytogenetic Map4E1UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.55UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386125,356,590 - 125,356,782UniSTSGRCm38
MGSCv376125,306,608 - 125,306,800UniSTSGRCm37
Celera6127,027,866 - 127,028,036UniSTS
Cytogenetic Map6F3UniSTS
cM Map660.55UniSTS
Tnfrsf1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386125,356,850 - 125,357,765UniSTSGRCm38
MGSCv376125,306,868 - 125,307,783UniSTSGRCm37
Celera6127,028,104 - 127,029,025UniSTS
Cytogenetic Map6F3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined695004651129004738Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696347325130347522Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696347325130347522Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698242853132242977Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698506837145935444Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698717516132717715Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698931748132940036Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699155128133155267Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103777444136423692Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104503360127042975Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104503360136423692Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110838217144838360Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111165485145165578Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112269957125356785Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112269957147052561Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114368732145656013Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115242853146429238Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115569842149572401Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115569842149572401Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115569842149572401Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115601042149601187Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115717516132601187Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116664897128519025Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116852888149736546Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117082986149736546Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120439808149736546Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124357314145656013Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125323797149736546Mouse
1300963Hrl_mherpes resistance locus (mouse)Not determined6125349723125362483Mouse
1301205Cms2_mresistance to Coccidioides immitis 2 (mouse)Not determined6125349723125362483Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125356646134119623Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1160
Count of miRNA genes:596
Interacting mature miRNAs:733
Transcripts:ENSMUST00000032491, ENSMUST00000125880, ENSMUST00000130257, ENSMUST00000131434, ENSMUST00000134803, ENSMUST00000144524
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC140324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY541589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY541590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK624043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L04800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L26349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M59377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S52703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X59238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032491   ⟹   ENSMUSP00000032491
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,349,723 - 125,362,484 (+)Ensembl
RefSeq Acc Id: ENSMUST00000125880   ⟹   ENSMUSP00000121968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,357,371 - 125,361,105 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130257   ⟹   ENSMUSP00000115991
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,349,451 - 125,357,316 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131434
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,349,362 - 125,350,035 (+)Ensembl
RefSeq Acc Id: ENSMUST00000134803
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,360,427 - 125,361,874 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144524   ⟹   ENSMUSP00000117470
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6125,357,765 - 125,361,778 (+)Ensembl
RefSeq Acc Id: NM_011609   ⟹   NP_035739
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396125,326,686 - 125,339,446 (+)NCBI
GRCm386125,349,723 - 125,362,483 (+)ENTREZGENE
MGSCv376125,299,741 - 125,312,501 (+)RGD
Celera6127,020,792 - 127,033,747 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035739   ⟸   NM_011609
- Peptide Label: precursor
- UniProtKB: P25118 (UniProtKB/Swiss-Prot),   Q3U479 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000121968   ⟸   ENSMUST00000125880
RefSeq Acc Id: ENSMUSP00000115991   ⟸   ENSMUST00000130257
RefSeq Acc Id: ENSMUSP00000117470   ⟸   ENSMUST00000144524
RefSeq Acc Id: ENSMUSP00000032491   ⟸   ENSMUST00000032491
Protein Domains
Death   TNFR-Cys

Promoters
RGD ID:6840099
Promoter ID:MM_KWN:47643
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000095449,   OTTMUST00000058165,   OTTMUST00000058190,   OTTMUST00000058191,   OTTMUST00000084343
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366125,299,461 - 125,299,982 (+)MPROMDB
RGD ID:6840098
Promoter ID:MM_KWN:47644
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000058192,   OTTMUST00000058194
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366125,306,431 - 125,307,717 (+)MPROMDB
RGD ID:6840097
Promoter ID:MM_KWN:47645
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver
Transcripts:OTTMUST00000058193
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366125,309,466 - 125,310,917 (+)MPROMDB
RGD ID:6891064
Promoter ID:EPDNEW_M8983
Type:initiation region
Name:Tnfrsf1a_1
Description:Mus musculus tumor necrosis factor receptor superfamily, member1a , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386125,349,730 - 125,349,790EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1314884 AgrOrtholog
Ensembl Genes ENSMUSG00000030341 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032491 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115991 UniProtKB/TrEMBL
  ENSMUSP00000117470 UniProtKB/TrEMBL
  ENSMUSP00000121968 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032491 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000125880 UniProtKB/TrEMBL
  ENSMUST00000130257 UniProtKB/TrEMBL
  ENSMUST00000144524 UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Death_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR/NGFR_Cys_rich_reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFRSF1A_death UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFRSF1A_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21937 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1314884 ENTREZGENE
NCBI Gene 21937 ENTREZGENE
Pfam Death UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_c6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TNFRSF1A RGD
PhenoGen Tnfrsf1a PhenoGen
PRINTS TNFACTORR1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DEATH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_NGFR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_NGFR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DEATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3YXL4_MOUSE UniProtKB/TrEMBL
  F6R6K0_MOUSE UniProtKB/TrEMBL
  F7A4X5_MOUSE UniProtKB/TrEMBL
  P25118 ENTREZGENE
  Q3TVS9_MOUSE UniProtKB/TrEMBL
  Q3U479 ENTREZGENE, UniProtKB/TrEMBL
  Q4VAE0_MOUSE UniProtKB/TrEMBL
  Q6QHF0_MOUSE UniProtKB/TrEMBL
  Q6QHF1_MOUSE UniProtKB/TrEMBL
  TNR1A_MOUSE UniProtKB/Swiss-Prot