Pfkm (phosphofructokinase, muscle) - Rat Genome Database

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Gene: Pfkm (phosphofructokinase, muscle) Mus musculus
Analyze
Symbol: Pfkm
Name: phosphofructokinase, muscle
RGD ID: 68622
MGI Page MGI
Description: Enables 6-phosphofructokinase activity and identical protein binding activity. Acts upstream of or within several processes, including glycogen catabolic process; glycolytic process through glucose-6-phosphate; and positive regulation of insulin secretion. Located in cytosol and sperm principal piece. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and musculoskeletal system. Used to study glycogen storage disease VII. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle); PARTICIPATES IN Fanconi syndrome pathway; glycogen storage disease type VII pathway; glycolysis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; AI131669; ATP-dependent 6-phosphofructokinase, muscle type; ATP-PFK; Pfk; Pfk-; Pfk-4; PFK-A; PFK-M; Pfk4; Pfka; Pfkx; phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase 4; phosphofructokinase M variant 3/4; phosphofructokinase, polypeptide X; phosphofructokinase-1 A isozyme; phosphofructokinase-M (connecting peptide); phosphohexokinase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,990,470 - 98,030,328 (+)NCBIGRCm39mm39
GRCm39 Ensembl1597,990,470 - 98,030,332 (+)Ensembl
GRCm381598,092,589 - 98,132,447 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,092,589 - 98,132,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv371597,923,020 - 97,962,878 (+)NCBIGRCm37mm9NCBIm37
MGSCv361597,940,155 - 97,960,485 (+)NCBImm8
Celera15100,219,444 - 100,262,084 (+)NCBICelera
Cytogenetic Map15F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-D  (ISO)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4-tert-Octylphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
alpha-naphthoflavone  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
ATP  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-D-fructofuranose 2,6-bisphosphate  (ISO)
bisphenol A  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
citric acid  (ISO)
clofibrate  (EXP)
clotrimazole  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin 460  (ISO)
daunorubicin  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dinophysistoxin 1  (ISO)
doxorubicin  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
gallic acid  (ISO)
indole-3-methanol  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
niclosamide  (ISO)
ochratoxin A  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:1833270   PMID:2521854   PMID:2822475   PMID:8110779   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11137296   PMID:11387227   PMID:11785984  
PMID:12477932   PMID:12819125   PMID:14610273   PMID:14633633   PMID:14681479   PMID:15020257   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16512683   PMID:16959763   PMID:17564308  
PMID:17595219   PMID:17626619   PMID:17720578   PMID:17967808   PMID:18469002   PMID:18799693   PMID:19696889   PMID:19779479   PMID:19889946   PMID:21074528   PMID:21267068   PMID:21573193  
PMID:21873635   PMID:23968980   PMID:24120946   PMID:27146165   PMID:27160897   PMID:27760309   PMID:28049690   PMID:28245920   PMID:29655163   PMID:30068389   PMID:30335684   PMID:30550785  
PMID:30562941   PMID:31914380   PMID:32325033  


Genomics

Comparative Map Data
Pfkm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,990,470 - 98,030,328 (+)NCBIGRCm39mm39
GRCm39 Ensembl1597,990,470 - 98,030,332 (+)Ensembl
GRCm381598,092,589 - 98,132,447 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,092,589 - 98,132,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv371597,923,020 - 97,962,878 (+)NCBIGRCm37mm9NCBIm37
MGSCv361597,940,155 - 97,960,485 (+)NCBImm8
Celera15100,219,444 - 100,262,084 (+)NCBICelera
Cytogenetic Map15F1NCBI
PFKM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1248,105,139 - 48,146,404 (+)EnsemblGRCh38hg38GRCh38
GRCh381248,105,353 - 48,146,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371248,499,136 - 48,540,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,802,817 - 46,826,154 (+)NCBINCBI36hg18NCBI36
Build 341246,802,814 - 46,826,154NCBI
Celera1247,297,160 - 47,337,691 (+)NCBI
Cytogenetic Map12q13.11NCBI
HuRef1245,531,136 - 45,571,668 (+)NCBIHuRef
CHM1_11248,465,088 - 48,505,624 (+)NCBICHM1_1
Pfkm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27129,221,679 - 129,259,192 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7129,221,653 - 129,259,192 (+)Ensembl
Rnor_6.07139,702,066 - 139,722,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,685,573 - 139,722,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,837,772 - 138,857,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,826,122 - 136,846,040 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,898,639 - 136,922,477 (+)NCBI
Celera7125,730,934 - 125,751,002 (+)NCBICelera
RH 3.4 Map71088.6RGD
Cytogenetic Map7q36NCBI
Pfkm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,978,893 - 7,022,309 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,979,169 - 7,020,375 (+)NCBIChiLan1.0ChiLan1.0
PFKM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11241,459,346 - 41,500,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,459,346 - 41,499,476 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01240,584,321 - 40,625,245 (-)NCBIMhudiblu_PPA_v0panPan3
PFKM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,620,300 - 6,640,649 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,620,300 - 6,663,670 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,641,501 - 39,686,323 (+)NCBI
ROS_Cfam_1.0276,687,848 - 6,732,671 (-)NCBI
UMICH_Zoey_3.1276,625,373 - 6,670,151 (-)NCBI
UNSW_CanFamBas_1.0276,660,147 - 6,704,882 (-)NCBI
UU_Cfam_GSD_1.02739,930,101 - 39,974,930 (+)NCBI
Pfkm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,132,891 - 67,175,202 (-)NCBI
SpeTri2.0NW_0049365126,006,247 - 6,031,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,475,540 - 78,526,995 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1578,475,473 - 78,525,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2581,673,123 - 81,695,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q25NCBI
PFKM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,332,857 - 44,378,273 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1144,334,605 - 44,377,877 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037202,000,136 - 202,046,219 (-)NCBIVero_WHO_p1.0
Pfkm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248164,132,511 - 4,156,809 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371597,924,575 - 97,925,638UniSTSGRCm37
MGSCv371597,923,971 - 97,925,588UniSTSGRCm37
MGSCv371597,924,591 - 97,925,588UniSTSGRCm37
MGSCv371597,923,957 - 97,925,638UniSTSGRCm37
Celera15100,220,381 - 100,222,062UniSTS
Celera15100,221,015 - 100,222,012UniSTS
Celera15100,220,395 - 100,222,012UniSTS
Celera15100,220,999 - 100,222,062UniSTS
Cytogenetic Map15F1UniSTS
cM Map15 UniSTS
cM Map1555.8UniSTS
cM Map1555.8UniSTS
cM Map1555.8UniSTS
cM Map1555.8UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,093,540 - 98,095,157UniSTSGRCm38
MGSCv371597,923,971 - 97,925,588UniSTSGRCm37
Celera15100,220,395 - 100,222,012UniSTS
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,093,526 - 98,095,207UniSTSGRCm38
MGSCv371597,923,957 - 97,925,638UniSTSGRCm37
Celera15100,220,381 - 100,222,062UniSTS
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,094,144 - 98,095,207UniSTSGRCm38
MGSCv371597,924,575 - 97,925,638UniSTSGRCm37
Celera15100,220,999 - 100,222,062UniSTS
Cytogenetic Map15F1UniSTS
Pfkm  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,094,160 - 98,095,157UniSTSGRCm38
MGSCv371597,924,591 - 97,925,588UniSTSGRCm37
Celera15100,221,015 - 100,222,012UniSTS
Cytogenetic Map15F1UniSTS
cM Map15 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402117102988123Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800000102100000Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154850000098500000Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548500000101800000Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556323312103517472Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564434485103517472Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156492762598927745Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156545237799456827Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156564117599641298Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567386497101386646Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570461452104043685Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570465070104043685Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570465070104043685Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572498466104043685Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573545941104043685Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577629711104043685Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78716903102993272Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578716903102993272Mouse
14928306Manh79_mmandible shape 79 (mouse)1578949676104043685Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1579000000104043685Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579265530104043685Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined80011059104043685Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580415753104043685Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580987052104043685Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580987052104043685Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82717593104043685Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585988005104043685Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585988005104043685Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585988005104043685Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585993114104043685Mouse
1301764Chab4_mcholesterol absorption 4 (mouse)Not determined1586751919104043685Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92890759103517472Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597800000103100000Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597987052102988123Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:346
Count of miRNA genes:157
Interacting mature miRNAs:161
Transcripts:ENSMUST00000051226, ENSMUST00000163507
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001163488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA420165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC113444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF249894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF357432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI930496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY226660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY782498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX218942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ428203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ428205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ428206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ428207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000051226   ⟹   ENSMUSP00000059801
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,006,347 - 98,030,322 (+)Ensembl
GRCm38.p6 Ensembl1598,108,466 - 98,132,441 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163507   ⟹   ENSMUSP00000132803
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,990,470 - 98,030,328 (+)Ensembl
GRCm38.p6 Ensembl1598,092,589 - 98,132,447 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229280   ⟹   ENSMUSP00000154896
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,990,470 - 98,018,787 (+)Ensembl
GRCm38.p6 Ensembl1598,092,589 - 98,120,906 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229344   ⟹   ENSMUSP00000155453
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,992,751 - 98,019,086 (+)Ensembl
GRCm38.p6 Ensembl1598,094,870 - 98,121,205 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230445   ⟹   ENSMUSP00000155809
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,990,525 - 98,030,332 (+)Ensembl
GRCm38.p6 Ensembl1598,092,644 - 98,132,451 (+)Ensembl
RefSeq Acc Id: NM_001163487   ⟹   NP_001156959
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,006,352 - 98,030,328 (+)NCBI
GRCm381598,108,471 - 98,132,447 (+)NCBI
MGSCv371597,923,020 - 97,962,878 (+)RGD
Celera15100,219,444 - 100,262,084 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001163488   ⟹   NP_001156960
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,990,470 - 98,030,328 (+)NCBI
GRCm381598,092,589 - 98,132,447 (+)ENTREZGENE
MGSCv371597,923,020 - 97,962,878 (+)RGD
Celera15100,219,444 - 100,262,084 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357688   ⟹   NP_001344617
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,006,437 - 98,030,328 (+)NCBI
GRCm381598,108,556 - 98,132,447 (+)NCBI
Sequence:
RefSeq Acc Id: NM_021514   ⟹   NP_067489
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,009,941 - 98,030,328 (+)NCBI
GRCm381598,112,060 - 98,132,447 (+)NCBI
MGSCv371597,923,020 - 97,962,878 (+)RGD
Celera15100,219,444 - 100,262,084 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520601   ⟹   XP_006520664
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,992,265 - 98,030,328 (+)NCBI
GRCm381598,093,288 - 98,132,447 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248412   ⟹   XP_030104272
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,992,265 - 98,030,328 (+)NCBI
GRCm381598,094,384 - 98,132,447 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_067489   ⟸   NM_021514
- UniProtKB: P47857 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001156960   ⟸   NM_001163488
- UniProtKB: P47857 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001156959   ⟸   NM_001163487
- UniProtKB: P47857 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520664   ⟸   XM_006520601
- Peptide Label: isoform X1
- UniProtKB: P47857 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030104272   ⟸   XM_030248412
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001344617   ⟸   NM_001357688
RefSeq Acc Id: ENSMUSP00000132803   ⟸   ENSMUST00000163507
RefSeq Acc Id: ENSMUSP00000059801   ⟸   ENSMUST00000051226
RefSeq Acc Id: ENSMUSP00000155809   ⟸   ENSMUST00000230445
RefSeq Acc Id: ENSMUSP00000155453   ⟸   ENSMUST00000229344
RefSeq Acc Id: ENSMUSP00000154896   ⟸   ENSMUST00000229280
Protein Domains
PFK

Promoters
RGD ID:6826320
Promoter ID:MM_KWN:19594
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:UC007XLV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,938,716 - 97,939,216 (+)MPROMDB
RGD ID:6826321
Promoter ID:MM_KWN:19595
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:UC007XLW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,942,326 - 97,942,826 (+)MPROMDB
RGD ID:8684886
Promoter ID:EPDNEW_M20474
Type:initiation region
Name:Pfkm_1
Description:Mus musculus phosphofructokinase, muscle , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20475  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381598,108,569 - 98,108,629EPDNEW
RGD ID:8684888
Promoter ID:EPDNEW_M20475
Type:initiation region
Name:Pfkm_2
Description:Mus musculus phosphofructokinase, muscle , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20474  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381598,112,077 - 98,112,137EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97548 AgrOrtholog
Ensembl Genes ENSMUSG00000033065 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059801 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000132803 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000154896 UniProtKB/TrEMBL
  ENSMUSP00000155453 UniProtKB/TrEMBL
  ENSMUSP00000155809 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000051226 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000163507 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000229280 UniProtKB/TrEMBL
  ENSMUST00000229344 UniProtKB/TrEMBL
  ENSMUST00000230445 UniProtKB/Swiss-Prot
InterPro 6-Pfructokinase_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_PFK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_PFK_prok-type UniProtKB/TrEMBL
  PFK_vert-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphofructokinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphofructokinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKF_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18642 UniProtKB/Swiss-Prot
MGD MGI:97548 ENTREZGENE
NCBI Gene 18642 ENTREZGENE
Pfam PFK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pfkm PhenoGen
PIRSF ATP_PFK_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_PFK_prok UniProtKB/TrEMBL
PRINTS PHFRCTKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PHOSPHOFRUCTOKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53784 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs 6PF1K_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHA5_MOUSE UniProtKB/TrEMBL
  A0A2R8VHV2_MOUSE UniProtKB/TrEMBL
  O35514_MOUSE UniProtKB/TrEMBL
  P47857 ENTREZGENE, UniProtKB/Swiss-Prot
  Q1LZL7_MOUSE UniProtKB/TrEMBL
  Q99K08_MOUSE UniProtKB/TrEMBL
UniProt Secondary C8CMN5 UniProtKB/Swiss-Prot
  C8CMN6 UniProtKB/Swiss-Prot
  C8CMN7 UniProtKB/Swiss-Prot
  O35513 UniProtKB/Swiss-Prot
  Q543L1 UniProtKB/Swiss-Prot
  Q9JK94 UniProtKB/Swiss-Prot