Sdhb (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)) - Rat Genome Database

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Gene: Sdhb (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)) Mus musculus
Analyze
Symbol: Sdhb
Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
RGD ID: 1318464
MGI Page MGI
Description: Predicted to enable iron-sulfur cluster binding activity; succinate dehydrogenase (quinone) activity; and ubiquinone binding activity. Predicted to be involved in aerobic respiration; respiratory electron transport chain; and succinate metabolic process. Located in mitochondrion. Part of respiratory chain complex II (succinate dehydrogenase). Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHB (succinate dehydrogenase complex iron sulfur subunit B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 0710008N11Rik; ip; iron-sulfur subunit of complex II; malate dehydrogenase [quinone] iron-sulfur subunit; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex subunit B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm19149  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,688,582 - 140,706,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,688,514 - 140,706,504 (+)EnsemblGRCm39 Ensembl
GRCm384140,961,271 - 140,979,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,961,203 - 140,979,193 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,517,186 - 140,535,108 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,233,347 - 140,251,269 (+)NCBIMGSCv36mm8
Celera4142,761,706 - 142,779,666 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
aspartame  (EXP)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
calycosin  (EXP,ISO)
carbon nanotube  (EXP)
celastrol  (EXP)
chloropicrin  (ISO)
choline  (EXP)
colistin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
desferrioxamine B  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
doxorubicin  (EXP)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenofibrate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (EXP,ISO)
hydrogen peroxide  (EXP)
isobutanol  (ISO)
isoniazide  (EXP)
isopimaric acid  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lamivudine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lenvatinib  (ISO)
lipopolysaccharide  (ISO)
maneb  (EXP)
melatonin  (EXP,ISO)
Mesaconitine  (ISO)
metformin  (EXP)
methimazole  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (ISO)
nickel dichloride  (ISO)
ochratoxin A  (ISO)
olaparib  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phlorizin  (EXP)
picoxystrobin  (ISO)
pramipexole  (ISO)
Pyridostigmine bromide  (ISO)
pyrimidifen  (ISO)
rac-1,2-dichloropropane  (EXP)
resveratrol  (EXP,ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
staurosporine  (EXP)
streptozocin  (EXP,ISO)
sulfadimethoxine  (ISO)
sulforaphane  (EXP)
T-2 toxin  (ISO)
talazoparib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
tolcapone  (ISO)
toluene  (ISO)
tributylstannane  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP,ISO)
valproic acid  (ISO)
zidovudine  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Astuti D, etal., Am J Hum Genet. 2001 Jul;69(1):49-54. Epub 2001 Jun 12.
2. SDH mutations in cancer. Bardella C, etal., Biochim Biophys Acta. 2011 Nov;1807(11):1432-43. doi: 10.1016/j.bbabio.2011.07.003. Epub 2011 Jul 13.
3. Succinate dehydrogenase deficiency in human. Briere JJ, etal., Cell Mol Life Sci. 2005 Oct;62(19-20):2317-24.
4. Surgically Metabolic Resection of Pericardial Fat to Ameliorate Myocardial Mitochondrial Dysfunction in Acute Myocardial Infarction Obese Rats. Kang KW, etal., J Korean Med Sci. 2022 Mar 7;37(9):e55. doi: 10.3346/jkms.2022.37.e55.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:3003061   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11583975   PMID:11829486   PMID:12477932   PMID:12865426   PMID:14610273   PMID:14681479  
PMID:15489334   PMID:15782199   PMID:16103131   PMID:16120479   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16751257   PMID:17376863   PMID:17626619   PMID:17634068   PMID:18614015  
PMID:18799693   PMID:19423573   PMID:19808025   PMID:19837698   PMID:21858060   PMID:21873635   PMID:22496890   PMID:22677546   PMID:22794259   PMID:23707781   PMID:24154540   PMID:24194600  
PMID:25348719   PMID:25695889   PMID:26123588   PMID:26302408   PMID:26522426   PMID:26876175   PMID:27113764   PMID:27215380   PMID:27453471   PMID:27626380   PMID:28159809   PMID:28204537  
PMID:28245920   PMID:28378742   PMID:29199018   PMID:29222160   PMID:29320742   PMID:29385670   PMID:29669786   PMID:30030361   PMID:30159755   PMID:30409884   PMID:30457570   PMID:30550785  
PMID:31575649   PMID:32212902   PMID:32234487   PMID:32248761   PMID:32325033   PMID:32525278   PMID:32732898   PMID:33663221   PMID:33691097   PMID:33913477   PMID:33947839   PMID:34048907  
PMID:34127497   PMID:34974310   PMID:35235785   PMID:35237793   PMID:35472723   PMID:35486677   PMID:35881479   PMID:36114006   PMID:36189989   PMID:36417873   PMID:36738738   PMID:36841836  
PMID:37225978   PMID:37353518   PMID:37545422   PMID:38320000   PMID:38355793   PMID:38414851   PMID:38418556   PMID:38505613   PMID:38588611  


Genomics

Comparative Map Data
Sdhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,688,582 - 140,706,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,688,514 - 140,706,504 (+)EnsemblGRCm39 Ensembl
GRCm384140,961,271 - 140,979,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,961,203 - 140,979,193 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,517,186 - 140,535,108 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,233,347 - 140,251,269 (+)NCBIMGSCv36mm8
Celera4142,761,706 - 142,779,666 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.24NCBI
SDHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,018,722 - 17,054,032 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,018,664 - 17,054,151 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,345,217 - 17,380,527 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,217,804 - 17,253,252 (-)NCBINCBI36Build 36hg18NCBI36
Build 34117,090,558 - 17,125,952NCBI
Celera115,667,559 - 15,703,013 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,589,311 - 15,624,677 (-)NCBIHuRef
CHM1_1117,453,561 - 17,489,010 (-)NCBICHM1_1
T2T-CHM13v2.0116,829,151 - 16,864,469 (-)NCBIT2T-CHM13v2.0
Sdhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,547,775 - 158,568,589 (+)NCBIGRCr8
mRatBN7.25153,264,906 - 153,285,570 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,264,899 - 153,314,293 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,953,279 - 155,973,810 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,726,549 - 157,747,081 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,715,729 - 157,736,265 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,484,378 - 159,505,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,484,370 - 159,505,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,197,045 - 163,217,315 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,818,669 - 159,839,772 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,828,844 - 159,849,873 (+)NCBI
Celera5151,629,862 - 151,650,475 (+)NCBICelera
Cytogenetic Map5q36NCBI
Sdhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,768,940 - 1,792,361 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,769,280 - 1,792,496 (+)NCBIChiLan1.0ChiLan1.0
SDHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,076,010 - 210,111,744 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,194,917 - 209,230,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,962,383 - 15,998,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,018,531 - 17,054,509 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,018,542 - 17,054,509 (-)Ensemblpanpan1.1panPan2
SDHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,158,291 - 81,190,110 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,158,291 - 81,190,109 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,695,312 - 77,727,188 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,804,258 - 81,836,607 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,804,258 - 81,836,606 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,557,290 - 78,589,612 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,574,320 - 79,606,173 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,642,748 - 80,674,635 (+)NCBIUU_Cfam_GSD_1.0
Sdhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,168,442 - 38,196,545 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,990,778 - 4,021,423 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,993,224 - 4,021,359 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SDHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,648,215 - 75,678,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,648,362 - 75,678,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,991,035 - 70,021,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SDHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,537,880 - 115,571,150 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,538,026 - 115,571,142 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033549,592 - 583,182 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sdhb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,650,604 - 2,679,005 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,655,138 - 2,679,138 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sdhb
720 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:381
Interacting mature miRNAs:434
Transcripts:ENSMUST00000010007, ENSMUST00000125780, ENSMUST00000129181
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137617848142289472Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse

Markers in Region
Sdhb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4E1UniSTS
cM Map4 UniSTS
UniSTS:235080  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384140,974,704 - 140,974,950UniSTSGRCm38
MGSCv374140,530,619 - 140,530,865UniSTSGRCm37
Celera4142,775,180 - 142,775,426UniSTS
Cytogenetic Map4E1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001355515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF095936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI835380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY111239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ403000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000010007   ⟹   ENSMUSP00000010007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4140,688,514 - 140,706,504 (+)Ensembl
GRCm38.p6 Ensembl4140,961,203 - 140,979,193 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4140,688,714 - 140,701,608 (+)Ensembl
GRCm38.p6 Ensembl4140,961,403 - 140,974,297 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129181
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4140,688,712 - 140,704,107 (+)Ensembl
GRCm38.p6 Ensembl4140,961,401 - 140,976,796 (+)Ensembl
RefSeq Acc Id: NM_001355515   ⟹   NP_001342444
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394140,688,582 - 140,706,509 (+)NCBI
GRCm384140,961,271 - 140,979,198 (+)NCBI
Sequence:
RefSeq Acc Id: NM_023374   ⟹   NP_075863
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394140,688,582 - 140,706,509 (+)NCBI
GRCm384140,961,271 - 140,979,198 (+)NCBI
MGSCv374140,517,186 - 140,535,108 (+)RGD
Celera4142,761,706 - 142,779,666 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_075863   ⟸   NM_023374
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3TF82 (UniProtKB/Swiss-Prot),   Q9DC91 (UniProtKB/Swiss-Prot),   Q9CQA3 (UniProtKB/Swiss-Prot),   Q3TE45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001342444   ⟸   NM_001355515
- Peptide Label: isoform 2
- UniProtKB: Q3TE45 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000010007   ⟸   ENSMUST00000010007
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CQA3-F1-model_v2 AlphaFold Q9CQA3 1-282 view protein structure

Promoters
RGD ID:6836366
Promoter ID:MM_KWN:40436
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000023450,   OTTMUST00000023451,   OTTMUST00000023452
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,516,956 - 140,517,456 (+)MPROMDB
RGD ID:6849167
Promoter ID:MM_XEF:5210
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_001080875,   NM_001086778,   NM_001098740,   NM_001126528,   NM_001141694,   NM_001170889
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,522,126 - 140,522,626 (+)MPROMDB
RGD ID:6885278
Promoter ID:EPDNEW_M6090
Type:multiple initiation site
Name:Sdhb_1
Description:Mus musculus succinate dehydrogenase complex, subunit B, ironsulfur , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384140,961,389 - 140,961,449EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914930 AgrOrtholog
Ensembl Genes ENSMUSG00000009863 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010007 ENTREZGENE
  ENSMUST00000010007.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1060.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.20.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 2Fe-2S_ferredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2Fe-2S_ferredoxin-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2Fe2S_fd_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4Fe4S_Fe-S-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4Fe4S_Fe_S_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Beta-grasp_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helical_ferredxn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDH/FRD_Iron-Sulfur UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Succ_DH/fum_Rdtase_Fe-S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Succ_DH/fum_Rdtase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67680 UniProtKB/Swiss-Prot
MGD MGI:1914930 ENTREZGENE
NCBI Gene 67680 ENTREZGENE
PANTHER SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Fer2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fer4_17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sdhb PhenoGen
PROSITE 2FE2S_FER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2FE2S_FER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4FE4S_FER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4FE4S_FER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP alpha-helical ferredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54292 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q0QEZ4_MOUSE UniProtKB/TrEMBL
  Q3TE45 ENTREZGENE, UniProtKB/TrEMBL
  Q3TF82 ENTREZGENE
  Q9CQA3 ENTREZGENE
  Q9DC91 ENTREZGENE
  Q9Z1Z5_MOUSE UniProtKB/TrEMBL
  SDHB_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TF82 UniProtKB/Swiss-Prot
  Q9DC91 UniProtKB/Swiss-Prot