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Gene: Sort1 (sortilin 1) Mus musculus
Symbol: Sort1
Name: sortilin 1
Description: Predicted to have several functions, including nerve growth factor binding activity; nerve growth factor receptor activity; and neurotensin receptor activity, non-G protein-coupled. Involved in several processes, including glucose import; myotube differentiation; and negative regulation of fat cell differentiation. Localizes to the cytoplasmic vesicle membrane; plasma membrane; and trans-Golgi network transport vesicle. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; paraxial mesenchyme; and retina. Orthologous to human SORT1 (sortilin 1); PARTICIPATES IN neurotrophic factor signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900053A11Rik; AI852375; mNTR3; neurotensin receptor 3; Ntr3; Ntsr3; sortilin
Homo sapiens (human) : SORT1 (sortilin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sort1 (sortilin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sort1 (sortilin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SORT1 (sortilin 1)
Canis lupus familiaris (dog) : SORT1 (sortilin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sort1 (sortilin 1)
Sus scrofa (pig) : SORT1 (sortilin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383108,283,974 - 108,361,519 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373108,087,050 - 108,164,429 (+)NCBIGRCm37mm9NCBIm37
MGSCv363108,412,188 - 108,489,567 (+)NCBImm8
Celera3110,641,971 - 110,695,156 (+)NCBICelera
Cytogenetic Map3 F2.3-F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sort1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731683
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.