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Gene: Mif (macrophage migration inhibitory factor (glycosylation-inhibiting factor)) Mus musculus
Symbol: Mif
Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Description: Exhibits cytokine activity; phenylpyruvate tautomerase activity; and protease binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of icosanoid secretion; and positive regulation of protein phosphorylation. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in allergic hypersensitivity disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human MIF (macrophage migration inhibitory factor); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH 1-fluoro-2,4-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: delayed early response protein 6; DER6; GIF; Glif; glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; MGC107654; phenylpyruvate tautomerase
Homo sapiens (human) : MIF (macrophage migration inhibitory factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mif (macrophage migration inhibitory factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mif (macrophage migration inhibitory factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MIF (macrophage migration inhibitory factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mif (macrophage migration inhibitory factor)
Sus scrofa (pig) : MIF (macrophage migration inhibitory factor)
more info ...
Related Pseudogenes: Gm11908   Gm20096   Mif-ps   Mif-ps1   Mif-ps3   Mif-ps6   Mif-ps7   Mif-ps8   Mif-ps9  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381075,859,353 - 75,860,277 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,322,098 - 75,322,995 (-)NCBIGRCm37mm9NCBIm37
MGSCv361075,303,069 - 75,303,966 (-)NCBImm8
Celera1076,904,043 - 76,904,940 (-)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1038.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mif
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734204
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.