Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rorb (RAR-related orphan receptor beta) Mus musculus
Analyze
Symbol: Rorb
Name: RAR-related orphan receptor beta
Description: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hstp; MGC38728; Nr1f2; nuclear receptor ROR-beta; nuclear receptor RZR-beta; nuclear receptor subfamily 1 group F member 2; retinoid-related orphan receptor-beta; Rorbeta; RZR-beta; RZRB
Orthologs:
Homo sapiens (human) : RORB (RAR related orphan receptor B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rorb (RAR-related orphan receptor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rorb (RAR related orphan receptor B)
Pan paniscus (bonobo/pygmy chimpanzee) : RORB (RAR related orphan receptor B)
Canis lupus familiaris (dog) : RORB (RAR related orphan receptor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rorb (RAR related orphan receptor B)
Sus scrofa (pig) : RORB (RAR related orphan receptor B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381918,930,609 - 19,111,196 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371919,011,058 - 19,185,686 (-)NCBIGRCm37mm9NCBIm37
MGSCv361919,003,591 - 19,068,140 (-)NCBImm8
Celera1919,621,464 - 19,802,185 (-)NCBICelera
Cytogenetic Map19 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rorb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315589
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-04-02
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.