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Gene: Penk (preproenkephalin) Mus musculus
Symbol: Penk
Name: preproenkephalin
Description: Predicted to have opioid receptor binding activity. Involved in several processes, including behavioral fear response; sensory perception of pain; and startle response. Predicted to localize to several cellular components, including cell body fiber; cytoplasmic vesicle lumen; and perikaryon. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PENK (proenkephalin); INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI326464; EN; ENK; Pe; Pen; Penk1; PPA; preproenkephalin 1; proenkephalin-A; spermatogenic-specific proenkephalin
Homo sapiens (human) : PENK (proenkephalin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Penk (proenkephalin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Penk (proenkephalin)
Pan paniscus (bonobo/pygmy chimpanzee) : PENK (proenkephalin)
Canis lupus familiaris (dog) : PENK (proenkephalin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Penk (proenkephalin)
Sus scrofa (pig) : PENK (proenkephalin)
Chlorocebus sabaeus (African green monkey) : PENK (proenkephalin)
Heterocephalus glaber (naked mole-rat) : Penk (proenkephalin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl44,133,531 - 4,138,819 (-)EnsemblGRCm38mm10GRCm38
GRCm3844,133,536 - 4,138,815 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3744,060,683 - 4,065,592 (-)NCBIGRCm37mm9NCBIm37
MGSCv3644,060,683 - 4,065,592 (-)NCBImm8
Celera44,092,742 - 4,097,651 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map42.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Penk
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68999
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.