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Gene: Calca (calcitonin/calcitonin-related polypeptide, alpha) Mus musculus
Symbol: Calca
Name: calcitonin/calcitonin-related polypeptide, alpha
Description: Exhibits calcitonin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of adenylate cyclase activity; and artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure. Localizes to several cellular components, including extracellular space; neuronal cell body; and terminal bouton. Is expressed in several structures, including gut; lung; nasal cavity; nervous system; and skin. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha CGRP; alpha-type CGRP; CA; Calc; Calc1; calcitonin; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin/alpha CGRP; Cgrp; CGRP-1; CGRP-I; CGRP1; Ct; Ctn
Homo sapiens (human) : CALCA (calcitonin related polypeptide alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Calca (calcitonin-related polypeptide alpha)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CALCA (calcitonin related polypeptide alpha)
Canis lupus familiaris (dog) : CRSP-3 (calcitonin receptor-stimulating peptide 3)
Sus scrofa (pig) : CALCB (calcitonin-related polypeptide beta)
Chlorocebus sabaeus (African green monkey) : CALCA (calcitonin related polypeptide alpha)
Heterocephalus glaber (naked mole-rat) : Calca (calcitonin related polypeptide alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)EnsemblGRCm38mm10GRCm38
GRCm387114,625,981 - 114,636,910 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377121,774,992 - 121,779,871 (-)NCBIGRCm37mm9NCBIm37
MGSCv367114,422,640 - 114,427,439 (-)NCBImm8
Celera7114,584,937 - 114,589,792 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Calca
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10274
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.