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Gene: Calca (calcitonin/calcitonin-related polypeptide, alpha) Mus musculus
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Symbol: Calca
Name: calcitonin/calcitonin-related polypeptide, alpha
Description: Exhibits calcitonin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of adenylate cyclase activity; and artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure. Localizes to several cellular components, including extracellular space; neuronal cell body; and terminal bouton. Is expressed in several structures, including gut; lung; nasal cavity; nervous system; and skin. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha CGRP; alpha-type CGRP; CA; Calc; Calc1; calcitonin; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin/alpha CGRP; Cgrp; CGRP-1; CGRP-I; CGRP1; Ct; Ctn
Orthologs:
Homo sapiens (human) : CALCA (calcitonin related polypeptide alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Calca (calcitonin-related polypeptide alpha)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CALCA (calcitonin related polypeptide alpha)
Canis lupus familiaris (dog) : CRSP-3 (calcitonin receptor-stimulating peptide 3)
Sus scrofa (pig) : CALCB (calcitonin-related polypeptide beta)
Chlorocebus sabaeus (African green monkey) : CALCA (calcitonin related polypeptide alpha)
Heterocephalus glaber (naked mole-rat) : Calca (calcitonin related polypeptide alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)EnsemblGRCm38mm10GRCm38
GRCm387114,625,981 - 114,636,910 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377121,774,992 - 121,779,871 (-)NCBIGRCm37mm9NCBIm37
MGSCv367114,422,640 - 114,427,439 (-)NCBImm8
Celera7114,584,937 - 114,589,792 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Calca
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10274
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.