Calca (calcitonin/calcitonin-related polypeptide, alpha) - Rat Genome Database

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Gene: Calca (calcitonin/calcitonin-related polypeptide, alpha) Mus musculus
Analyze
Symbol: Calca
Name: calcitonin/calcitonin-related polypeptide, alpha
RGD ID: 10274
MGI Page MGI
Description: Enables calcitonin receptor binding activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure; and detection of temperature stimulus involved in sensory perception of pain. Located in cytoplasm; extracellular region; and terminal bouton. Is expressed in several structures, including genitourinary system; gut; lung; nasal cavity; and nervous system. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to several human genes including CALCA (calcitonin related polypeptide alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: alpha CGRP; alpha-type CGRP; C; CA; Calc; Calc1; calcitonin; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin/alpha CGRP; Cg; Cgrp; CGRP-1; CGRP-I; CGRP1; Ct; Ctn
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397114,225,223 - 114,236,145 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7114,230,713 - 114,235,592 (-)EnsemblGRCm39 Ensembl
GRCm387114,625,981 - 114,636,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv377121,774,992 - 121,779,871 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367114,422,640 - 114,427,439 (-)NCBIMGSCv36mm8
Celera7114,584,937 - 114,589,792 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide  (ISO)
(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin  (ISO)
(R)-adrenaline  (ISO)
(R)-noradrenaline  (ISO)
(S)-amphetamine  (ISO)
1,2-dichloroethane  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide  (ISO)
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  (ISO)
4-hydroxynon-2-enal  (ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (EXP)
4-methylcatechol  (EXP)
5-azacytidine  (ISO)
6-oxoprostaglandin F1alpha  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylcholine  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alachlor  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
allyl isothiocyanate  (ISO)
amiloride  (EXP)
aminoguanidine  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
Anetholtrithion  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
ATP  (ISO)
atropine  (ISO)
Bay-K-8644  (ISO)
benzo[a]pyrene  (EXP,ISO)
bethanechol  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Botulinum toxin type A  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
capsaicin  (EXP,ISO)
capsazepine  (EXP,ISO)
carbon dioxide  (ISO)
carbon nanotube  (EXP)
carvedilol  (ISO)
chelerythrine  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt atom  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corn oil  (EXP)
corticosterone  (ISO)
corticotropin  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
D-glucose  (EXP,ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
disodium cromoglycate  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
eletriptan  (ISO)
entinostat  (ISO)
epothilone B  (ISO)
ergotamine  (ISO)
ethanol  (EXP,ISO)
etoposide  (ISO)
fentanyl  (ISO)
fenvalerate  (ISO)
flavonoids  (ISO)
flurbiprofen  (ISO)
folic acid  (EXP,ISO)
fructose  (EXP,ISO)
Gallopamil  (ISO)
genistein  (EXP)
gentamycin  (ISO)
Ginkgolide A  (EXP)
glucose  (EXP,ISO)
glycidol  (ISO)
glyphosate  (ISO)
GR 127935  (ISO)
haloperidol  (ISO)
histamine  (ISO)
hydrogen chloride  (ISO)
ibuprofen  (ISO)
ICI 118551  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
isoflurane  (ISO)
isoprenaline  (ISO)
KT 5720  (ISO)
Lafutidine  (ISO)
lead diacetate  (ISO)
lidocaine  (EXP,ISO)
linsidomine  (ISO)
lipopolysaccharide  (EXP,ISO)
LY294002  (ISO)
lycopene  (ISO)
magnesium atom  (EXP)
melatonin  (EXP)
methimazole  (ISO)
methylene blue  (ISO)
methylmercury chloride  (ISO)
methysergide  (ISO)
Mibefradil  (ISO)
morphine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naloxone  (ISO)
nefopam  (ISO)
nimodipine  (ISO)
nitrendipine  (ISO)
nitrofen  (ISO)
nitroglycerin  (ISO)
nitroprusside  (ISO)
nizatidine  (ISO)
NONOate(1-)  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pemirolast  (ISO)
phenol  (ISO)
Phenoxybenzamine  (ISO)
phenylephrine  (EXP,ISO)
phenytoin  (ISO)
pirinixic acid  (ISO)
potassium atom  (EXP,ISO)
potassium chloride  (ISO)
potassium dichromate  (EXP)
procaine  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
propranolol  (ISO)
prostaglandin E2  (ISO)
ranitidine  (ISO)
rebaudioside A  (ISO)
resiniferatoxin  (EXP)
resveratrol  (ISO)
Rizatriptan benzoate  (ISO)
rofecoxib  (ISO)
ruthenium red  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
safranal  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
serotonin  (ISO)
sevoflurane  (ISO)
silicon carbide  (ISO)
silicon dioxide  (ISO)
sodium chloride  (EXP,ISO)
Soman  (ISO)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
sulprostone  (ISO)
sumatriptan  (ISO)
suramin  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
topiramate  (ISO)
trichostatin A  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
Tryptanthrine  (ISO)
Tungsten carbide  (ISO)
UTP  (ISO)
valproic acid  (ISO)
verapamil  (ISO)
veratridine  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IBA,IGI)
antimicrobial humoral immune response mediated by antimicrobial peptide  (ISO)
artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure  (IMP)
calcitonin gene-related peptide receptor signaling pathway  (ISO)
cell adhesion  (IDA)
cellular response to nerve growth factor stimulus  (IDA,ISO)
cellular response to tumor necrosis factor  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (IMP)
embryo implantation  (ISO)
endothelial cell migration  (ISO)
endothelial cell proliferation  (ISO)
feeding behavior  (IDA)
G protein-coupled receptor internalization  (ISO)
inflammatory response  (IDA)
innate immune response  (ISO)
intracellular calcium ion homeostasis  (IGI)
leukocyte cell-cell adhesion  (ISO)
monocyte chemotaxis  (ISO)
negative regulation of blood pressure  (IMP,ISA,ISO)
negative regulation of bone resorption  (ISO)
negative regulation of calcium ion transport into cytosol  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of ossification  (IMP)
negative regulation of osteoclast differentiation  (ISO)
negative regulation of smooth muscle contraction  (IDA,ISO)
nervous system process involved in regulation of systemic arterial blood pressure  (ISA)
neuropeptide signaling pathway  (IDA)
ossification  (IMP)
phospholipase C-activating G protein-coupled receptor signaling pathway  (ISO)
positive regulation of cell adhesion  (IDA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of interleukin-1 alpha production  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of macrophage differentiation  (ISO)
receptor internalization  (ISO)
regulation of cytosolic calcium ion concentration  (IBA)
response to heat  (IMP)
response to pain  (IMP)
smooth muscle contraction  (IDA)
sperm capacitation  (ISA)
vasculature development  (ISO)
vasodilation  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat. Abdelmagid N, etal., PLoS Pathog. 2012;8(6):e1002753. doi: 10.1371/journal.ppat.1002753. Epub 2012 Jun 28.
2. Pattern of distribution of calcitonin gene-related Peptide in the dorsal root ganglion of animal models of diabetes mellitus. Adeghate E, etal., Ann N Y Acad Sci. 2006 Nov;1084:296-303.
3. Altered calcitonin gene in a young patient with osteoporosis. Alevizaki M, etal., BMJ 1989 May 6;298(6682):1215-6.
4. The calcitonin/calcitonin gene related peptide-alpha gene is not required for 1alpha,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis. Becklund BR, etal., Arch Biochem Biophys. 2009 Aug 15;488(2):105-8. Epub 2009 Jun 27.
5. Role of calcitonin gene-related peptide in hypertension-induced renal damage. Bowers MC, etal., Hypertension. 2005 Jul;46(1):51-7. Epub 2005 May 31.
6. Nerve Growth Factor Mediates Mechanical Allodynia in a Mouse Model of Type 2 Diabetes. Cheng HT, etal., J Neuropathol Exp Neurol. 2009 Oct 7.
7. Intranasal Calcitonin Gene-Related Peptide Protects Against Focal Cerebral Ischemic Injury in Rats Through the Wnt/β-Catenin Pathway. Du Z, etal., Med Sci Monit. 2018 Dec 7;24:8860-8869. doi: 10.12659/MSM.913777.
8. The protective effects of calcitonin gene-related peptide on gastric mucosa injury after cerebral ischemia reperfusion in rats. Feng G, etal., Regul Pept. 2010 Feb 25;160(1-3):121-8. Epub 2009 Nov 10.
9. Anti-inflammatory effects of limb ischaemic preconditioning are mediated by sensory nerve activation in rats. Hartmann P, etal., Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):179-89. Epub 2010 Dec 23.
10. Using IL-2R/lymphocytes for predicting the clinical progression of patients with COVID-19. Hou H, etal., Clin Exp Immunol. 2020 Jul;201(1):76-84. doi: 10.1111/cei.13450. Epub 2020 May 15.
11. Mapping of glutathione transferase (GST) genes in the rat. Klinga-Levan K, etal., Hereditas 1993;119(3):285-96.
12. BDNF and CGRP interaction: implications in migraine susceptibility. Lemos C, etal., Cephalalgia. 2010 Nov;30(11):1375-82. Epub 2010 May 10.
13. Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study. Lin YT, etal., J Neuroinflammation. 2011 Sep 30;8:126. doi: 10.1186/1742-2094-8-126.
14. Calcitonin gene-related peptide prevents blood-brain barrier injury and brain edema induced by focal cerebral ischemia reperfusion. Liu Z, etal., Regul Pept. 2011 Nov 10;171(1-3):19-25. Epub 2011 Jun 28.
15. Association study of calcitonin gene-related polypeptide-alpha (CALCA) gene polymorphism with migraine. Menon S, etal., Brain Res. 2011 Mar 10;1378:119-24. Epub 2010 Dec 31.
16. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
17. MGDs mouse GO annotations MGD data from the GO Consortium
18. MGD IEA MGD IEA
19. Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats. Mizutani A, etal., Anesthesiology. 2009 Feb;110(2):361-9. doi: 10.1097/ALN.0b013e3181942f3c.
20. Neuropeptides in the rat corpus cavernosum and seminal vesicle: effects of age and two types of diabetes. Morrison JF, etal., Auton Neurosci. 2009 Mar 12;146(1-2):76-80. Epub 2009 Jan 17.
21. Comparative mapping of novel simple sequence repeat markers in a hypertension-related region on rat chromosome 1. Nabika T, etal., Mamm Genome 1997 Mar;8(3):215-7.
22. Procalcitonin: a marker of severity of acute pyelonephritis among children. Pecile P, etal., Pediatrics. 2004 Aug;114(2):e249-54.
23. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Qiu H, etal., Lancet Infect Dis. 2020 Jun;20(6):689-696. doi: 10.1016/S1473-3099(20)30198-5. Epub 2020 Mar 25.
24. Mouse MP Annotation Import Pipeline RGD automated import pipeline
25. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
26. Calcitonin gene-related peptide expression levels predict motor neuron vulnerability in the superoxide dismutase 1-G93A mouse model of amyotrophic lateral sclerosis. Ringer C, etal., Neurobiol Dis. 2012 Jan;45(1):547-54. Epub 2011 Sep 21.
27. Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis. Schneider L, etal., Pancreatology. 2009;9(5):662-9. Epub 2009 Aug 14.
28. Calcitonin gene-related peptide protects against hypertension-induced heart and kidney damage. Supowit SC, etal., Hypertension. 2005 Jan;45(1):109-14. Epub 2004 Dec 6.
29. Clinical features and treatment of COVID-19 patients in northeast Chongqing. Wan S, etal., J Med Virol. 2020 Jul;92(7):797-806. doi: 10.1002/jmv.25783. Epub 2020 Apr 1.
30. Clinical characteristics and outcomes of patients with severe covid-19 with diabetes. Yan Y, etal., BMJ Open Diabetes Res Care. 2020 Apr;8(1). pii: 8/1/e001343. doi: 10.1136/bmjdrc-2020-001343.
Additional References at PubMed
PMID:1317267   PMID:1423499   PMID:1889815   PMID:1981054   PMID:2307474   PMID:2882956   PMID:3146546   PMID:6690234   PMID:7521790   PMID:7530767   PMID:7587380   PMID:7588260  
PMID:7613043   PMID:7635047   PMID:7698182   PMID:7913017   PMID:7955356   PMID:8261138   PMID:8278635   PMID:8328969   PMID:8453761   PMID:8565843   PMID:8582325   PMID:8609367  
PMID:8637595   PMID:8735980   PMID:8806650   PMID:8809809   PMID:8833147   PMID:8876243   PMID:8891945   PMID:8896700   PMID:8938454   PMID:8955272   PMID:8992876   PMID:9013986  
PMID:9073507   PMID:9092472   PMID:9126746   PMID:9217002   PMID:9268129   PMID:9271704   PMID:9303529   PMID:9322931   PMID:9422725   PMID:9520319   PMID:9590297   PMID:9675049  
PMID:9724458   PMID:9797472   PMID:9834195   PMID:9838101   PMID:9853118   PMID:10024383   PMID:10208559   PMID:10212310   PMID:10331972   PMID:10341242   PMID:10349636   PMID:10482239  
PMID:10532808   PMID:10536054   PMID:10642343   PMID:10752955   PMID:10860579   PMID:10952889   PMID:11042159   PMID:11076861   PMID:11166483   PMID:11208722   PMID:11217851   PMID:11274425  
PMID:11276224   PMID:11466438   PMID:11518254   PMID:11551509   PMID:11683995   PMID:11717154   PMID:11733510   PMID:11748295   PMID:11761712   PMID:11832378   PMID:11893340   PMID:11897091  
PMID:11930150   PMID:12012374   PMID:12024028   PMID:12070080   PMID:12118100   PMID:12150774   PMID:12160745   PMID:12183023   PMID:12270041   PMID:12352981   PMID:12376349   PMID:12466851  
PMID:12477932   PMID:12488435   PMID:12527144   PMID:12629553   PMID:12704735   PMID:12810600   PMID:12815622   PMID:12815759   PMID:12888222   PMID:12904337   PMID:14527739   PMID:14765981  
PMID:14973275   PMID:14985435   PMID:15016615   PMID:15039145   PMID:15082182   PMID:15201551   PMID:15236465   PMID:15278951   PMID:15448099   PMID:15468368   PMID:15489334   PMID:15531135  
PMID:15537449   PMID:15549366   PMID:15591414   PMID:15607543   PMID:15714282   PMID:15836427   PMID:15964817   PMID:16040009   PMID:16118273   PMID:16133146   PMID:16133151   PMID:16141072  
PMID:16141073   PMID:16142452   PMID:16143644   PMID:16157679   PMID:16331648   PMID:16342117   PMID:16446141   PMID:16446142   PMID:16497798   PMID:16530166   PMID:16530750   PMID:16580148  
PMID:16602821   PMID:16675524   PMID:16973277   PMID:16978876   PMID:17002587   PMID:17087955   PMID:17101855   PMID:17103415   PMID:17116257   PMID:17141159   PMID:17145500   PMID:17164259  
PMID:17307998   PMID:17369402   PMID:17396120   PMID:17419680   PMID:17482477   PMID:17495962   PMID:17530400   PMID:17540505   PMID:17553423   PMID:17579082   PMID:17595340   PMID:17618297  
PMID:17656431   PMID:17666428   PMID:17676639   PMID:17693550   PMID:17697146   PMID:17765889   PMID:17906370   PMID:17923674   PMID:17954614   PMID:17986107   PMID:18005945   PMID:18006238  
PMID:18054007   PMID:18155191   PMID:18160659   PMID:18163477   PMID:18192222   PMID:18203709   PMID:18307972   PMID:18374910   PMID:18385258   PMID:18430544   PMID:18430798   PMID:18455988  
PMID:18498732   PMID:18498735   PMID:18554416   PMID:18619948   PMID:18706490   PMID:18757308   PMID:18757746   PMID:18771734   PMID:18789524   PMID:18799693   PMID:18839409   PMID:18941191  
PMID:18959118   PMID:18985716   PMID:19016003   PMID:19017671   PMID:19046367   PMID:19053061   PMID:19062206   PMID:19235715   PMID:19235728   PMID:19261615   PMID:19288186   PMID:19381879  
PMID:19445917   PMID:19465128   PMID:19498280   PMID:19502490   PMID:19574443   PMID:19786540   PMID:19805384   PMID:19824062   PMID:19850157   PMID:19860701   PMID:19897741   PMID:20034568  
PMID:20035772   PMID:20048339   PMID:20058222   PMID:20064392   PMID:20096094   PMID:20139349   PMID:20141542   PMID:20147383   PMID:20231872   PMID:20346763   PMID:20359526   PMID:20498049  
PMID:20534813   PMID:20610563   PMID:20697379   PMID:20844136   PMID:20852037   PMID:20951772   PMID:21061159   PMID:21129374   PMID:21131474   PMID:21151121   PMID:21220101   PMID:21243003  
PMID:21266507   PMID:21267068   PMID:21364918   PMID:21408140   PMID:21471385   PMID:21514666   PMID:21543603   PMID:21546103   PMID:21606356   PMID:21752988   PMID:21765217   PMID:21873635  
PMID:21893556   PMID:22008794   PMID:22028026   PMID:22040871   PMID:22048169   PMID:22048787   PMID:22132122   PMID:22152428   PMID:22288475   PMID:22326227   PMID:22331706   PMID:22345400  
PMID:22421361   PMID:22427743   PMID:22491945   PMID:22563493   PMID:22586115   PMID:22661927   PMID:22696295   PMID:22718343   PMID:22721614   PMID:22787056   PMID:22797898   PMID:22828515  
PMID:22878413   PMID:22886599   PMID:22922231   PMID:23047698   PMID:23132245   PMID:23133534   PMID:23261435   PMID:23306833   PMID:23357366   PMID:23389451   PMID:23416515   PMID:23451260  
PMID:23462102   PMID:23462468   PMID:23462960   PMID:23509367   PMID:23523592   PMID:23526213   PMID:23532063   PMID:23562608   PMID:23587546   PMID:23591430   PMID:23616538   PMID:23665221  
PMID:23671638   PMID:23686616   PMID:23707896   PMID:23790753   PMID:23804090   PMID:23806407   PMID:23816470   PMID:23924632   PMID:24021706   PMID:24027274   PMID:24121436   PMID:24275230  
PMID:24360544   PMID:24371813   PMID:24466057   PMID:24516108   PMID:24516396   PMID:24633961   PMID:24717410   PMID:24733831   PMID:24760869   PMID:24794145   PMID:24853942   PMID:24952961  
PMID:24992521   PMID:25080603   PMID:25127920   PMID:25184332   PMID:25269705   PMID:25316186   PMID:25333900   PMID:25356765   PMID:25369838   PMID:25406633   PMID:25489075   PMID:25536054  
PMID:25631042   PMID:25707377   PMID:25762373   PMID:25788675   PMID:25834049   PMID:25857228   PMID:25915476   PMID:25968320   PMID:26010480   PMID:26073142   PMID:26075897   PMID:26186190  
PMID:26235626   PMID:26265538   PMID:26356988   PMID:26377461   PMID:26395490   PMID:26403381   PMID:26427874   PMID:26453796   PMID:26506449   PMID:26555052   PMID:26743624   PMID:26822917  
PMID:26858598   PMID:26892431   PMID:27022966   PMID:27076429   PMID:27150575   PMID:27166945   PMID:27301688   PMID:27335464   PMID:27388773   PMID:27440744   PMID:27497681   PMID:27553639  
PMID:27554772   PMID:27659421   PMID:27861515   PMID:28002412   PMID:28119454   PMID:28167615   PMID:28324021   PMID:28346423   PMID:28348418   PMID:28581479   PMID:28666011   PMID:28695626  
PMID:28792272   PMID:28817806   PMID:28833700   PMID:28892747   PMID:28971837   PMID:29031500   PMID:29045838   PMID:29054601   PMID:29055051   PMID:29103805   PMID:29184212   PMID:29213229  
PMID:29266061   PMID:29361553   PMID:29386099   PMID:29421662   PMID:29543503   PMID:29562230   PMID:29709471   PMID:29864146   PMID:29874580   PMID:29913443   PMID:29925650   PMID:29950483  
PMID:29972353   PMID:29978952   PMID:30068853   PMID:30197585   PMID:30204499   PMID:30208315   PMID:30344042   PMID:30348676   PMID:30352200   PMID:30389913   PMID:30446499   PMID:30449655  
PMID:30451912   PMID:30651296   PMID:30662401   PMID:30674976   PMID:30700848   PMID:30768367   PMID:30884088   PMID:30917305   PMID:30917309   PMID:30976911   PMID:31152445   PMID:31219353  
PMID:31231869   PMID:31331823   PMID:31351040   PMID:31353223   PMID:31396962   PMID:31426665   PMID:31541644   PMID:31562139   PMID:31585080   PMID:31604686   PMID:31618654   PMID:31627131  
PMID:31631837   PMID:31636950   PMID:31665965   PMID:31682159   PMID:31724338   PMID:31730854   PMID:31781038   PMID:31801063   PMID:31926346   PMID:31955990   PMID:32038174   PMID:32088381  
PMID:32142630   PMID:32239544   PMID:32352932   PMID:32371135   PMID:32446790   PMID:32488015   PMID:32591941   PMID:32673294   PMID:32723474   PMID:32848807   PMID:32853990   PMID:32856589  
PMID:33232717   PMID:33285241   PMID:33288908   PMID:33382180   PMID:33412345   PMID:33431851   PMID:33691135   PMID:33715169   PMID:33744254   PMID:33772088   PMID:33789102   PMID:33839113  
PMID:33917574   PMID:34061020   PMID:34270926   PMID:34321664   PMID:34338291   PMID:34462445   PMID:34497269   PMID:34580157   PMID:35031579   PMID:35075189   PMID:35233469   PMID:35303432  
PMID:35507386   PMID:35577801   PMID:35681537   PMID:35700066   PMID:35760098   PMID:35875660   PMID:35904071   PMID:35977501   PMID:35993206   PMID:36047655   PMID:36243004   PMID:36293102  
PMID:36317965   PMID:36333314   PMID:36334588   PMID:36473754   PMID:36639374   PMID:36640762   PMID:36706592   PMID:36810601   PMID:36859544   PMID:36867267   PMID:36973009   PMID:37122730  
PMID:37192624   PMID:37321223   PMID:37541195   PMID:37603775   PMID:37733805   PMID:37874659   PMID:38167468   PMID:38396204  


Genomics

Comparative Map Data
Calca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397114,225,223 - 114,236,145 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7114,230,713 - 114,235,592 (-)EnsemblGRCm39 Ensembl
GRCm387114,625,981 - 114,636,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv377121,774,992 - 121,779,871 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367114,422,640 - 114,427,439 (-)NCBIMGSCv36mm8
Celera7114,584,937 - 114,589,792 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.99NCBI
CALCA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381114,966,668 - 14,972,351 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1114,966,622 - 14,972,354 (-)EnsemblGRCh38hg38GRCh38
GRCh371114,988,214 - 14,993,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,944,792 - 14,950,408 (-)NCBINCBI36Build 36hg18NCBI36
Build 341114,946,625 - 14,950,427NCBI
Celera1115,115,335 - 15,120,952 (-)NCBICelera
Cytogenetic Map11p15.2NCBI
HuRef1114,671,857 - 14,677,473 (-)NCBIHuRef
CHM1_11114,987,226 - 14,992,843 (-)NCBICHM1_1
T2T-CHM13v2.01115,063,025 - 15,068,708 (-)NCBIT2T-CHM13v2.0
Calca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,312,636 - 178,317,588 (-)NCBIGRCr8
mRatBN7.21168,878,212 - 168,883,176 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,878,214 - 168,883,105 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,192,440 - 177,197,339 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,378,496 - 184,383,399 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01177,090,892 - 177,095,773 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,184,018 - 184,188,922 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,184,020 - 184,188,911 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,158,061 - 191,162,954 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,686,168 - 172,691,061 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11172,824,299 - 172,827,127 (-)NCBI
Celera1166,711,610 - 166,716,491 (-)NCBICelera
RH 3.4 Map11317.6RGD
RH 2.0 Map1757.3RGD
Cytogenetic Map1q34NCBI
CALCA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2917,335,385 - 17,340,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,296,273 - 17,300,935 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01115,055,897 - 15,061,539 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11114,745,588 - 14,751,267 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1114,745,588 - 14,751,267 (-)Ensemblpanpan1.1panPan2
CRSP-3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12137,676,841 - 37,680,643 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2137,676,841 - 37,680,645 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2137,176,307 - 37,180,108 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02138,770,713 - 38,774,520 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2138,770,713 - 38,774,522 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.02137,993,320 - 37,997,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02138,281,026 - 38,284,825 (+)NCBIUU_Cfam_GSD_1.0
Calca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494747,766,690 - 47,772,207 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365283,800,577 - 3,805,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365283,800,801 - 3,806,000 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALCB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1244,043,135 - 44,048,651 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2247,248,414 - 47,253,904 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103239768
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1149,946,574 - 49,956,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl149,951,694 - 49,954,092 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038147,447,203 - 147,453,110 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247666,766,185 - 6,768,173 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247666,764,388 - 6,771,396 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Calca
301 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:251
Count of miRNA genes:206
Interacting mature miRNAs:219
Transcripts:ENSMUST00000032906, ENSMUST00000032907
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
4141056Lskcn2_mLSK cell number 2 (mouse)Not determined108482996118693530Mouse
35673311Ari6_mantibody response to influenza 6, day 15, IgG2b (mouse)7108699207115099235Mouse
25394557Skmw64_mskeletal muscle weight 64, soleus (mouse)7108715780114592736Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse

Markers in Region
PMC109322P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387114,633,736 - 114,634,574UniSTSGRCm38
MGSCv377121,777,250 - 121,778,088UniSTSGRCm37
Celera7114,587,169 - 114,588,007UniSTS
Cytogenetic Map7F1UniSTS
cM Map754.0UniSTS
PMC151647P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387114,635,991 - 114,636,295UniSTSGRCm38
MGSCv377121,779,505 - 121,779,809UniSTSGRCm37
Celera7114,589,426 - 114,589,730UniSTS
Cytogenetic Map7F1UniSTS
cM Map754.0UniSTS
X97991  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387114,633,391 - 114,633,473UniSTSGRCm38
MGSCv377121,776,905 - 121,776,987UniSTSGRCm37
Celera7114,586,824 - 114,586,906UniSTS
Cytogenetic Map7F1UniSTS
cM Map754.0UniSTS
Whitehead/MRC_RH71175.47UniSTS
Calca  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
cM Map754.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001305616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC156617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF078167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF330212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH010528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB749493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU842988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ057527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ060164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X97991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032906   ⟹   ENSMUSP00000032906
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,230,713 - 114,235,592 (-)Ensembl
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)Ensembl
RefSeq Acc Id: ENSMUST00000032907   ⟹   ENSMUSP00000032907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,232,528 - 114,235,547 (-)Ensembl
GRCm38.p6 Ensembl7114,633,293 - 114,636,312 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,230,803 - 114,231,880 (-)Ensembl
GRCm38.p6 Ensembl7114,631,568 - 114,632,645 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205714   ⟹   ENSMUSP00000146280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,233,607 - 114,235,506 (-)Ensembl
GRCm38.p6 Ensembl7114,634,372 - 114,636,271 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205933   ⟹   ENSMUSP00000145548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,233,576 - 114,235,541 (-)Ensembl
GRCm38.p6 Ensembl7114,634,341 - 114,636,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206156   ⟹   ENSMUSP00000145756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,231,787 - 114,235,542 (-)Ensembl
GRCm38.p6 Ensembl7114,632,552 - 114,636,307 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206853   ⟹   ENSMUSP00000146328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7114,232,645 - 114,235,530 (-)Ensembl
GRCm38.p6 Ensembl7114,633,410 - 114,636,295 (-)Ensembl
RefSeq Acc Id: NM_001033954   ⟹   NP_001029126
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,230,713 - 114,235,592 (-)NCBI
GRCm387114,631,478 - 114,636,357 (-)NCBI
MGSCv377121,774,992 - 121,779,871 (-)RGD
Celera7114,584,937 - 114,589,792 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001289444   ⟹   NP_001276373
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,230,713 - 114,235,592 (-)NCBI
GRCm387114,631,478 - 114,636,357 (-)NCBI
Celera7114,584,937 - 114,589,792 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001305616   ⟹   NP_001292545
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,232,526 - 114,235,592 (-)NCBI
GRCm387114,633,291 - 114,636,357 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007587   ⟹   NP_031613
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,232,526 - 114,235,592 (-)NCBI
GRCm387114,633,291 - 114,636,357 (-)NCBI
MGSCv377121,774,992 - 121,779,871 (-)RGD
Celera7114,584,937 - 114,589,792 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011241660   ⟹   XP_011239962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,225,223 - 114,236,145 (-)NCBI
GRCm387114,625,981 - 114,636,910 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242031   ⟹   XP_030097891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,232,526 - 114,236,145 (-)NCBI
GRCm387114,633,291 - 114,636,910 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242032   ⟹   XP_030097892
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397114,230,718 - 114,236,145 (-)NCBI
GRCm387114,631,483 - 114,636,910 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001029126   ⟸   NM_001033954
- Peptide Label: isoform Cgrp preproprotein
- UniProtKB: Q99JA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_031613   ⟸   NM_007587
- Peptide Label: isoform Calca preproprotein
- UniProtKB: Q8K1K5 (UniProtKB/Swiss-Prot),   P70160 (UniProtKB/Swiss-Prot),   Q3V1A7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276373   ⟸   NM_001289444
- Peptide Label: isoform Cgrp preproprotein
- UniProtKB: Q99JA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011239962   ⟸   XM_011241660
- Peptide Label: isoform X2
- UniProtKB: Q99JA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001292545   ⟸   NM_001305616
- Peptide Label: isoform Calca preproprotein
- UniProtKB: Q8K1K5 (UniProtKB/Swiss-Prot),   P70160 (UniProtKB/Swiss-Prot),   Q3V1A7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030097892   ⟸   XM_030242032
- Peptide Label: isoform X2
- UniProtKB: Q99JA0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030097891   ⟸   XM_030242031
- Peptide Label: isoform X1
- UniProtKB: P70160 (UniProtKB/Swiss-Prot),   Q8K1K5 (UniProtKB/Swiss-Prot),   Q3V1A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000032906   ⟸   ENSMUST00000032906
RefSeq Acc Id: ENSMUSP00000032907   ⟸   ENSMUST00000032907
RefSeq Acc Id: ENSMUSP00000145756   ⟸   ENSMUST00000206156
RefSeq Acc Id: ENSMUSP00000146328   ⟸   ENSMUST00000206853
RefSeq Acc Id: ENSMUSP00000145548   ⟸   ENSMUST00000205933
RefSeq Acc Id: ENSMUSP00000146280   ⟸   ENSMUST00000205714
Protein Domains
Calcitonin peptide-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70160-F1-model_v2 AlphaFold P70160 1-136 view protein structure

Promoters
RGD ID:8665297
Promoter ID:EPDNEW_M10680
Type:multiple initiation site
Name:Calca_1
Description:Mus musculus calcitonin/calcitonin-related polypeptide, alpha, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387114,636,309 - 114,636,369EPDNEW
RGD ID:6840762
Promoter ID:MM_KWN:52375
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Spleen
Transcripts:NM_001033954,   NM_007587
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367121,779,716 - 121,780,437 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2151253 AgrOrtholog
Ensembl Genes ENSMUSG00000030669 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032906 ENTREZGENE
  ENSMUST00000032906.11 UniProtKB/Swiss-Prot
  ENSMUST00000032907 ENTREZGENE
  ENSMUST00000032907.9 UniProtKB/Swiss-Prot
  ENSMUST00000205714.2 UniProtKB/TrEMBL
  ENSMUST00000205933.2 UniProtKB/TrEMBL
  ENSMUST00000206156.2 UniProtKB/TrEMBL
  ENSMUST00000206853 ENTREZGENE
  ENSMUST00000206853.2 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.250.2190 UniProtKB/Swiss-Prot
InterPro Calcitonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calcitonin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calcitonin/adrenomedullin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calcitonin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calcitonin_gene-rel_peptide UniProtKB/Swiss-Prot
  Calcitonin_peptide-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12310 UniProtKB/Swiss-Prot
MGD MGI:2151253 ENTREZGENE
NCBI Gene 12310 ENTREZGENE
PANTHER CALCITONIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CALCITONIN GENE-RELATED PEPTIDE 2 UniProtKB/Swiss-Prot
  PTHR10505 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Calc_CGRP_IAPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CALCA RGD
PhenoGen Calca PhenoGen
PRINTS CALCITONINA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CALCITONINB UniProtKB/Swiss-Prot
PROSITE CALCITONIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CALCITONIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RNG0_MOUSE UniProtKB/TrEMBL
  A0A0U1RNZ0_MOUSE UniProtKB/TrEMBL
  CALC_MOUSE UniProtKB/Swiss-Prot
  CALCA_MOUSE UniProtKB/Swiss-Prot
  P70160 ENTREZGENE
  Q3V1A7 ENTREZGENE, UniProtKB/TrEMBL
  Q8K1K5 ENTREZGENE
  Q99JA0 ENTREZGENE
UniProt Secondary Q8K1K5 UniProtKB/Swiss-Prot