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Gene: Ak2 (adenylate kinase 2) Mus musculus
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Symbol: Ak2
Name: adenylate kinase 2
RGD ID: 10130
Description: Predicted to contribute to nucleobase-containing compound kinase activity. Predicted to be involved in ATP metabolic process and purine nucleotide metabolic process. Localizes to sperm mitochondrial sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2); PARTICIPATES IN adefovir pharmacokinetics pathway; de novo purine biosynthetic pathway; tenofovir pharmacokinetics pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate kinase 2, mitochondrial; adenylate monophosphate kinase; AK 2; Ak-; Ak-2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; D4Ertd220; D4Ertd220e
Orthologs:
Homo sapiens (human) : AK2 (adenylate kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ak2 (adenylate kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak2 (adenylate kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AK2 (adenylate kinase 2)
Canis lupus familiaris (dog) : AK2 (adenylate kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak2 (adenylate kinase 2)
Sus scrofa (pig) : AK2 (adenylate kinase 2)
Chlorocebus sabaeus (African green monkey) : AK2 (adenylate kinase 2)
Heterocephalus glaber (naked mole-rat) : Ak2 (adenylate kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl4128,991,958 - 129,011,529 (+)EnsemblGRCm38mm10GRCm38
GRCm384128,993,224 - 129,011,529 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374128,670,509 - 128,688,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv364128,495,569 - 128,513,833 (+)NCBImm8
Celera4127,337,482 - 127,350,601 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ak2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10130
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.