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Gene: Ak2 (adenylate kinase 2) Mus musculus
Symbol: Ak2
Name: adenylate kinase 2
RGD ID: 10130
Description: Predicted to contribute to nucleobase-containing compound kinase activity. Predicted to be involved in ATP metabolic process and purine nucleotide metabolic process. Localizes to sperm mitochondrial sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2); PARTICIPATES IN adefovir pharmacokinetics pathway; de novo purine biosynthetic pathway; tenofovir pharmacokinetics pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate kinase 2, mitochondrial; adenylate monophosphate kinase; AK 2; Ak-; Ak-2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; D4Ertd220; D4Ertd220e
Homo sapiens (human) : AK2 (adenylate kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ak2 (adenylate kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak2 (adenylate kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AK2 (adenylate kinase 2)
Canis lupus familiaris (dog) : AK2 (adenylate kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak2 (adenylate kinase 2)
Sus scrofa (pig) : AK2 (adenylate kinase 2)
Chlorocebus sabaeus (African green monkey) : AK2 (adenylate kinase 2)
Heterocephalus glaber (naked mole-rat) : Ak2 (adenylate kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4128,991,958 - 129,011,529 (+)EnsemblGRCm38mm10GRCm38
GRCm384128,993,224 - 129,011,529 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374128,670,509 - 128,688,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv364128,495,569 - 128,513,833 (+)NCBImm8
Celera4127,337,482 - 127,350,601 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ak2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10130
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.