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Gene: Nr5a2 (nuclear receptor subfamily 5, group A, member 2) Mus musculus
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Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cellular response to leukemia inhibitory factor; cholesterol homeostasis; and pancreas morphogenesis. Localizes to the RNA polymerase II transcription factor complex. Is expressed in several structures, including alimentary system; central nervous system; ear; early conceptus; and gonad. Orthologous to human NR5A2 (nuclear receptor subfamily 5 group A member 2); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH 1,2-dilauroyl-sn-glycero-3-phosphocholine(1+); 1-O-oleoyl-sn-glycero-3-phosphocholine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU020803; D1Ertd308e; fetoprotein transcription factor; Ftf; liver receptor homolog 1; LRH-1; nuclear receptor subfamily 5 group A member 2; UF2-H3B
Orthologs:
Homo sapiens (human) : NR5A2 (nuclear receptor subfamily 5 group A member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr5a2 (nuclear receptor subfamily 5, group A, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr5a2 (nuclear receptor subfamily 5 group A member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR5A2 (nuclear receptor subfamily 5 group A member 2)
Canis lupus familiaris (dog) : NR5A2 (nuclear receptor subfamily 5 group A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr5a2 (nuclear receptor subfamily 5 group A member 2)
Sus scrofa (pig) : NR5A2 (nuclear receptor subfamily 5 group A member 2)
more info ...
Related Pseudogenes: Gm17743   Gm18981  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381136,842,562 - 136,960,448 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371138,740,161 - 138,857,025 (-)NCBIGRCm37mm9NCBIm37
MGSCv361138,660,687 - 138,776,859 (-)NCBImm8
Celera1139,488,247 - 139,612,651 (-)NCBICelera
Cytogenetic Map1 E4NCBI
cM Map159.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr5a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68500
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.