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Gene: Numbl (numb-like) Mus musculus
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Symbol: Numbl
Name: numb-like
Description: Predicted to have cadherin binding activity. Involved in adherens junction organization and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including central nervous system; peripheral nervous system ganglion; sensory organ; testis; and thymus. Orthologous to human NUMBL (NUMB like endocytic adaptor protein); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: nbl; numb-like protein
Orthologs:
Homo sapiens (human) : NUMBL (NUMB like endocytic adaptor protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Numbl (NUMB-like, endocytic adaptor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Numbl (NUMB like endocytic adaptor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : NUMBL (NUMB like endocytic adaptor protein)
Canis lupus familiaris (dog) : NUMBL (NUMB like endocytic adaptor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Numbl (NUMB like endocytic adaptor protein)
Sus scrofa (pig) : NUMBL (NUMB like endocytic adaptor protein)
Chlorocebus sabaeus (African green monkey) : NUMBL (NUMB like endocytic adaptor protein)
Heterocephalus glaber (naked mole-rat) : Numbl (NUMB like endocytic adaptor protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl727,258,433 - 27,282,144 (+)EnsemblGRCm38mm10GRCm38
GRCm38727,258,438 - 27,282,150 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37728,043,780 - 28,067,169 (+)NCBIGRCm37mm9NCBIm37
MGSCv36726,967,521 - 26,990,910 (+)NCBImm8
Celera721,835,674 - 21,859,077 (+)NCBICelera
Cytogenetic Map7A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Numbl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316855
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.