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Gene: Numbl (numb-like) Mus musculus
Symbol: Numbl
Name: numb-like
Description: Predicted to have cadherin binding activity. Involved in adherens junction organization and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including central nervous system; peripheral nervous system ganglion; sensory organ; testis; and thymus. Orthologous to human NUMBL (NUMB like endocytic adaptor protein); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: nbl; numb-like protein
Homo sapiens (human) : NUMBL (NUMB like endocytic adaptor protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Numbl (NUMB-like, endocytic adaptor protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Numbl (NUMB like endocytic adaptor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : NUMBL (NUMB like endocytic adaptor protein)
Canis lupus familiaris (dog) : NUMBL (NUMB like endocytic adaptor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Numbl (NUMB like endocytic adaptor protein)
Sus scrofa (pig) : NUMBL (NUMB like endocytic adaptor protein)
Chlorocebus sabaeus (African green monkey) : NUMBL (NUMB like endocytic adaptor protein)
Heterocephalus glaber (naked mole-rat) : Numbl (NUMB like endocytic adaptor protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl727,258,433 - 27,282,144 (+)EnsemblGRCm38mm10GRCm38
GRCm38727,258,438 - 27,282,150 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37728,043,780 - 28,067,169 (+)NCBIGRCm37mm9NCBIm37
MGSCv36726,967,521 - 26,990,910 (+)NCBImm8
Celera721,835,674 - 21,859,077 (+)NCBICelera
Cytogenetic Map7A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Numbl
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316855
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.