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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antiparkinson drug
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Accession:CHEBI:48407 term browser browse the term
Definition:A drug used in the treatment of Parkinson's disease.
Synonyms:related_synonym: antiparkinson agent
 xref: Wikipedia:Antiparkinson


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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 multiple interactions
affects localization		 ISO A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
amantadine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA CTD PMID:19211973 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO Amantadine results in increased expression of IFI27 mRNA CTD PMID:16756086 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 affects expression ISO Amantadine affects the expression of IFNAR1 mRNA CTD PMID:16756086 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Amantadine results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO Amantadine results in decreased expression of MAP2 mRNA CTD PMID:34748853 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Amantadine results in increased expression of OAS2 mRNA CTD PMID:16756086 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Amantadine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Amantadine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1 CTD PMID:15918519 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 decreases activity ISO Amantadine analog results in decreased activity of TDP1 protein CTD PMID:29248742 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021 		JBrowse link
apomorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amy1 amylase alpha 1 multiple interactions EXP Apomorphine results in increased secretion of and results in increased activity of AMY1A protein; Atenolol inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein]; Metoclopramide inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816 		JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions		 ISO Apomorphine results in increased expression of AVP protein
Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein]		 CTD PMID:16575035 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form] CTD PMID:25633564 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A decreases expression ISO Apomorphine results in decreased expression of BMPR1A mRNA CTD PMID:25633564 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cck cholecystokinin multiple interactions
decreases activity		 EXP Naloxone inhibits the reaction [CCK protein results in decreased activity of Apomorphine] CTD PMID:3561887 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance ISO CCKBR protein affects the susceptibility to Apomorphine CTD PMID:11702094 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Apomorphine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
Apomorphine binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]		 CTD PMID:8103921 PMID:15985612 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects response to substance
increases response to substance		 EXP
ISO		 Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]
DRD2 protein affects the susceptibility to Apomorphine
DRD2 protein results in increased susceptibility to Apomorphine
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]		 CTD PMID:2571179 PMID:7520908 PMID:8103596 PMID:8103921 PMID:14639100 More... NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 increases response to substance ISO DRD3 protein results in increased susceptibility to Apomorphine CTD PMID:19497322 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Apomorphine results in increased expression of FOS protein CTD PMID:10904129 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Apomorphine results in decreased expression of FURIN mRNA CTD PMID:25633564 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP GDNF protein affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gh1 growth hormone 1 increases secretion
increases expression		 ISO Apomorphine results in increased secretion of GH1 protein
Apomorphine results in increased expression of GH1 protein		 CTD PMID:993808 PMID:8889285 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases secretion
decreases expression		 ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Apomorphine results in decreased secretion of HAMP protein modified form
Apomorphine results in decreased expression of HAMP mRNA		 CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] CTD PMID:8539317 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases response to substance
multiple interactions		 EXP HTR6 protein results in increased susceptibility to Apomorphine
Ro4368554 inhibits the reaction [HTR6 protein results in increased susceptibility to Apomorphine]		 CTD PMID:17920665 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Apomorphine inhibits the reaction [Oxidopamine results in increased phosphorylation of JUN protein] CTD PMID:14599342 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO Apomorphine results in increased activity of ODC1 protein CTD PMID:10354516 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Penk proenkephalin multiple interactions EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] CTD PMID:17719177 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Prl prolactin decreases expression ISO Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Pvalb parvalbumin affects expression EXP Apomorphine affects the expression of PVALB protein CTD PMID:15238432 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Apomorphine CTD PMID:15728856 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions EXP SHH protein modified form affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:207,031,369...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:17719177 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
benserazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO
EXP		 COMT protein results in increased methylation of Benserazide CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO Benserazide binds to and results in decreased activity of DDC protein CTD PMID:35151785 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [Oxidopamine co-treated with levodopa methyl ester] promotes the reaction [Benserazide results in increased expression of DRD1 protein] CTD PMID:19399396 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP [Oxidopamine co-treated with levodopa methyl ester] inhibits the reaction [Benserazide results in increased expression of DRD2 protein] CTD PMID:19399396 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
benzatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Benztropine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Benztropine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767 		JBrowse link
G Actr1a actin related protein 1A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ACTR1A protein CTD PMID:34122009 NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495 		JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Benztropine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760 		JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Benztropine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Anxa1 annexin A1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ANXA1 protein CTD PMID:34122009 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 decreases expression ISO Benztropine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa6 annexin A6 decreases expression ISO Benztropine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Anxa7 annexin A7 increases expression ISO Benztropine results in increased expression of ANXA7 protein CTD PMID:34122009 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Benztropine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Benztropine results in decreased expression of ASNS protein CTD PMID:34122009 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Benztropine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Benztropine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ATP5C1 protein CTD PMID:34122009 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Benztropine results in decreased expression of ATP6V1B2 protein CTD PMID:34122009 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atxn10 ataxin 10 increases expression ISO Benztropine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression ISO Benztropine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BLTP1 protein CTD PMID:34122009 NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Benztropine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388 		JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Benztropine results in decreased expression of BSG protein CTD PMID:34122009 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Cald1 caldesmon 1 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of CALD1 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of CALD1 protein		 CTD PMID:34122009 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calu calumenin decreases expression ISO Benztropine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CAMK2D protein CTD PMID:34122009 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CAPRIN1 protein CTD PMID:34122009 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CASP8AP2 protein CTD PMID:34122009 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Benztropine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc121rt coiled-coil domain containing 121, retrotransposed increases expression ISO Benztropine results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr13:93,253,752...93,255,406
Ensembl chr13:93,254,387...93,255,358 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT6A protein CTD PMID:34122009 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Benztropine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cd276 Cd276 molecule decreases expression ISO Benztropine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cenpv centromere protein V increases expression ISO Benztropine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Benztropine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Ckb creatine kinase B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CKB protein CTD PMID:34122009 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CNP protein
Benztropine results in decreased expression of CNP protein		 CTD PMID:34122009 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL14A1 protein CTD PMID:34122009 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Benztropine results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887 		JBrowse link
G Coro1b coronin 1B decreases expression ISO Benztropine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CORO7 protein CTD PMID:34122009 NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001 		JBrowse link
G Cpne3 copine 3 decreases expression ISO Benztropine results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 5:33,014,658...33,064,004
Ensembl chr 5:33,016,307...33,063,934 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CPSF3 protein CTD PMID:34122009 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G Crtap cartilage associated protein increases expression ISO Benztropine results in increased expression of CRTAP protein CTD PMID:34122009 NCBI chr 8:114,047,929...114,067,648
Ensembl chr 8:114,047,933...114,067,631 		JBrowse link
G Cryz crystallin zeta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CRYZ protein CTD PMID:34122009 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csde1 cold shock domain containing E1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CSDE1 protein CTD PMID:34122009 NCBI chr 2:190,546,015...190,582,790
Ensembl chr 2:190,554,980...190,582,784 		JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 decreases expression ISO Benztropine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476 		JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CTBP1 protein CTD PMID:34122009 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Cul2 cullin 2 increases expression ISO Benztropine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr17:54,169,086...54,210,197
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cul4b cullin 4B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CUL4B protein CTD PMID:34122009 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DARS2 protein CTD PMID:34122009 NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934 		JBrowse link
G Dazap1 DAZ associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DAZAP1 protein CTD PMID:34122009 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Dctn2 dynactin subunit 2 increases expression ISO Benztropine results in increased expression of DCTN2 protein CTD PMID:34122009 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543 		JBrowse link
G Ddx17 DEAD-box helicase 17 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX17 protein CTD PMID:34122009 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX3X protein CTD PMID:34122009 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Benztropine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benztropine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhx8 DEAH-box helicase 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DHX8 protein CTD PMID:34122009 NCBI chr10:86,667,641...86,705,454
Ensembl chr10:86,667,834...86,705,137 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DLAT protein
Benztropine results in increased expression of DLAT protein		 CTD PMID:34122009 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Benztropine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Benztropine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Benztropine results in decreased expression of DPYSL2 protein CTD PMID:34122009 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:35,374,429...35,480,462
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Benztropine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EBNA1BP2 protein CTD PMID:34122009 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression ISO Benztropine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3B protein CTD PMID:34122009 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H decreases expression ISO Benztropine results in decreased expression of EIF3H protein CTD PMID:34122009 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L increases expression
multiple interactions		 ISO Benztropine results in increased expression of EIF3L protein
[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3L protein		 CTD PMID:34122009 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5 protein CTD PMID:34122009 NCBI chr 6:130,589,200...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5B protein
Benztropine results in increased expression of EIF5B protein		 CTD PMID:34122009 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Benztropine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Benztropine results in decreased expression of ENO1 protein CTD PMID:34122009 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ephb3 Eph receptor B3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EPHB3 protein CTD PMID:34122009 NCBI chr11:79,840,668...79,859,467
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Epn1 Epsin 1 decreases expression ISO Benztropine results in decreased expression of EPN1 protein CTD PMID:34122009 NCBI chr 1:68,742,491...68,760,507
Ensembl chr 1:68,742,789...68,758,874 		JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Benztropine results in decreased expression of EPS8 protein CTD PMID:34122009 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Erh ERH, mRNA splicing and mitosis factor increases expression ISO Benztropine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr 6:100,280,930...100,291,449
Ensembl chr 6:100,280,930...100,291,210 		JBrowse link
G Erlin2 ER lipid raft associated 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ERLIN2 protein CTD PMID:34122009 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO Benztropine results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544 		JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EXOSC9 protein CTD PMID:34122009 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G Ezr ezrin decreases expression ISO Benztropine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression ISO Benztropine results in increased expression of FABP3 protein CTD PMID:34122009 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FDPS protein CTD PMID:34122009 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Flot2 flotillin 2 increases expression ISO Benztropine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Benztropine results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FYCO1 protein CTD PMID:34122009 NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021 		JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of G3BP2 protein CTD PMID:34122009 NCBI chr14:15,932,356...16,020,555
Ensembl chr14:15,987,417...16,020,548 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Benztropine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GART protein CTD PMID:34122009 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gatad2b GATA zinc finger domain containing 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GATAD2B protein CTD PMID:34122009 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542 		JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GDA protein CTD PMID:34122009 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 decreases expression ISO Benztropine results in decreased expression of GFPT1 protein CTD PMID:34122009 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein CTD PMID:34122009 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Benztropine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Gls glutaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GLS protein CTD PMID:34122009 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gna12 G protein subunit alpha 12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GNA12 protein CTD PMID:34122009 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Golga4 golgin A4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOLGA4 protein CTD PMID:34122009 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Golgb1 golgin B1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOT2 protein CTD PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO Benztropine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpkow G patch domain and KOW motifs multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GPKOW protein CTD PMID:34122009 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384 		JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 decreases expression ISO Benztropine results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr11:63,182,073...63,215,349
Ensembl chr11:63,182,349...63,213,942 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GTF2F1 protein CTD PMID:34122009 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423 		JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO Benztropine results in increased expression of GTPBP4 protein CTD PMID:34122009 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009 		JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GYS1 protein CTD PMID:34122009 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292 		JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Benztropine results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Benztropine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Benztropine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Benztropine results in increased expression of HARS protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hat1 histone acetyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517 		JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638 		JBrowse link
G Hmcn2 hemicentin 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HMCN2 protein CTD PMID:34122009 NCBI chr 3:14,588,353...14,738,320
Ensembl chr 3:14,588,662...14,738,025 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Benztropine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HPS3 protein CTD PMID:34122009 NCBI chr 2:102,484,574...102,527,580
Ensembl chr 2:102,484,574...102,526,047 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Benztropine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HSP90B1 protein CTD PMID:34122009 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Benztropine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benztropine results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression ISO Benztropine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Jam3 junctional adhesion molecule 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of JAM3 protein CTD PMID:34122009 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein CTD PMID:34122009 NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170 		JBrowse link
G Kars1 lysyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KARS protein CTD PMID:34122009 NCBI chr19:39,957,846...39,976,886
Ensembl chr19:39,957,846...39,977,632 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benztropine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Benztropine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr15:79,800,077...79,806,064
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO Benztropine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Benztropine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187 		JBrowse link
G Klhl41 kelch-like family member 41 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KLHL41 protein CTD PMID:34122009 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Benztropine results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081 		JBrowse link
G Ktn1 kinectin 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein
Benztropine results in decreased expression of KTN1 protein		 CTD PMID:34122009 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578 		JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Benztropine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMB1 protein CTD PMID:34122009 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMC1 protein CTD PMID:34122009 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LIMA1 protein CTD PMID:34122009 NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Benztropine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lmod2 leiomodin 2 increases expression ISO Benztropine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LSS protein CTD PMID:34122009 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Luc7l LUC7-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LUC7L protein CTD PMID:34122009 NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112 		JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGEA9 protein CTD PMID:34122009 NCBI chr  X:142,619,282...142,624,654
Ensembl chr  X:142,619,395...142,624,653 		JBrowse link
G Maged2 MAGE family member D2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGED2 protein CTD PMID:34122009 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477 		JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Benztropine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988 		JBrowse link
G Map4 microtubule-associated protein 4 decreases expression ISO Benztropine results in decreased expression of MAP4 protein CTD PMID:34122009 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases expression ISO Benztropine results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Marcksl1 MARCKS-like 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MARCKSL1 protein CTD PMID:34122009 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817 		JBrowse link
G Mat2b methionine adenosyltransferase 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein CTD PMID:34122009 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 decreases expression ISO Benztropine results in decreased expression of MBOAT7 protein CTD PMID:34122009 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Benztropine results in decreased expression of MDH1 protein CTD PMID:34122009 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Benztropine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 NCBI chr 7:28,412,771...28,440,458
Ensembl chr 7:28,411,608...28,440,434 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Benztropine results in increased expression of MIF protein CTD PMID:34122009 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mtdh metadherin multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MTDH protein CTD PMID:34122009 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MTHFD1L protein CTD PMID:34122009 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Myh3 myosin heavy chain 3 increases expression ISO Benztropine results in increased expression of MYH3 protein CTD PMID:34122009 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992 		JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO Benztropine results in decreased expression of NAT10 protein CTD PMID:34122009 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Benztropine results in decreased expression of NCBP1 protein CTD PMID:34122009 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Benztropine results in decreased expression of NECTIN2 protein CTD PMID:34122009 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Benztropine results in increased expression of NNMT protein CTD PMID:34122009 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO Benztropine results in increased expression of NOC2L protein CTD PMID:34122009 NCBI chr 5:166,820,075...166,831,951
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO Benztropine results in decreased expression of NSF protein CTD PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nsfl1c NSFL1 cofactor decreases expression ISO Benztropine results in decreased expression of NSFL1C protein CTD PMID:34122009 NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of NUMA1 protein CTD PMID:34122009 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855 		JBrowse link
G Nup153 nucleoporin 153 increases expression ISO Benztropine results in increased expression of NUP153 protein CTD PMID:34122009 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876 		JBrowse link
G Nup50 nucleoporin 50 increases expression ISO Benztropine results in increased expression of NUP50 protein CTD PMID:34122009 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905 		JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Benztropine results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028 		JBrowse link
G Nup93 nucleoporin 93 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NUP93 protein CTD PMID:34122009 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026 		JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NXF1 protein CTD PMID:34122009 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO Benztropine results in decreased expression of OGDH protein CTD PMID:34122009 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Ola1 Obg-like ATPase 1 increases expression ISO Benztropine results in increased expression of OLA1 protein CTD PMID:34122009 NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Benztropine results in decreased expression of P4HB protein CTD PMID:34122009 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PA2G4 protein CTD PMID:34122009 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PAFAH1B1 protein CTD PMID:34122009 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Benztropine results in decreased expression of PAG1 protein CTD PMID:34122009 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein
Benztropine results in decreased expression of PARP1 protein		 CTD PMID:34122009 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PC protein CTD PMID:34122009 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PCBP1 protein CTD PMID:34122009 NCBI chr 4:118,972,698...118,974,722
Ensembl chr 4:118,972,661...118,976,500 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 decreases expression ISO Benztropine results in decreased expression of PCBP2 protein CTD PMID:34122009 NCBI chr 7:133,605,480...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Pcdhga2 protocadherin gamma subfamily A, 2 decreases expression ISO Benztropine results in decreased expression of PCDHGA2 protein CTD PMID:34122009 NCBI chr18:29,493,954...29,667,865
Ensembl chr18:29,493,954...29,667,868 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Benztropine results in increased expression of PCNP protein CTD PMID:34122009 NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348 		JBrowse link
G Pdcl3 phosducin-like 3 decreases expression ISO Benztropine results in decreased expression of PDCL3 protein CTD PMID:34122009 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression ISO Benztropine results in decreased expression of PDIA3 protein CTD PMID:34122009 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PDIA6 protein CTD PMID:34122009 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Benztropine results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Benztropine results in decreased expression of PEBP1 protein CTD PMID:34122009 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Pfn1 profilin 1 increases expression ISO Benztropine results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Benztropine results in decreased expression of PGK1 protein CTD PMID:34122009 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgm3 phosphoglucomutase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PGM3 protein CTD PMID:34122009 NCBI chr 8:87,517,931...87,536,034
Ensembl chr 8:87,517,701...87,536,022 		JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PHF14 protein CTD PMID:34122009 NCBI chr 4:40,009,691...40,195,870
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Benztropine results in decreased expression of PHGDH protein CTD PMID:34122009 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Benztropine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PIN1 protein CTD PMID:34122009 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression ISO Benztropine results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844 		JBrowse link
G Pnma1 PNMA family member 1 increases expression ISO Benztropine results in increased expression of PNMA1 protein CTD PMID:34122009 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567 		JBrowse link
G Pnma8a PNMA family member 8A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PNMA8A protein CTD PMID:34122009 NCBI chr 1:77,629,272...77,643,156
Ensembl chr 1:77,639,423...77,642,082 		JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PON3 protein CTD PMID:34122009 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPA1 protein
Benztropine results in increased expression of PPA1 protein		 CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F decreases expression ISO Benztropine results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PPP1R12A protein CTD PMID:34122009 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Benztropine results in increased expression of PPP3CA protein CTD PMID:34122009 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRKAR2A protein CTD PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkcsh protein kinase C substrate 80K-H multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PRMT1 protein CTD PMID:34122009 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Prpf6 pre-mRNA processing factor 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRPF6 protein CTD PMID:34122009 NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Benztropine results in decreased expression of PSMA1 protein CTD PMID:34122009 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO Benztropine results in decreased expression of PSMB7 protein CTD PMID:34122009 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 decreases expression ISO Benztropine results in decreased expression of PSMC1 protein CTD PMID:34122009 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression ISO Benztropine results in increased expression of PSMC3 protein CTD PMID:34122009 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression ISO Benztropine results in increased expression of PSMD7 protein CTD PMID:34122009 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588 		JBrowse link
G Ptcd3 Pentatricopeptide repeat domain 3 increases expression
multiple interactions		 ISO Benztropine results in increased expression of PTCD3 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of PTCD3 protein		 CTD PMID:34122009 NCBI chr 4:103,922,440...103,957,445
Ensembl chr 4:103,920,566...103,957,538 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Benztropine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk7 protein tyrosine kinase 7 decreases expression ISO Benztropine results in decreased expression of PTK7 protein CTD PMID:34122009 NCBI chr 9:14,352,155...14,418,494
Ensembl chr 9:14,351,202...14,418,494 		JBrowse link
G Puf60 poly-U binding splicing factor 60 decreases expression ISO Benztropine results in decreased expression of PUF60 protein CTD PMID:34122009 NCBI chr 7:107,782,770...107,793,814
Ensembl chr 7:107,782,770...107,794,531 		JBrowse link
G Pwp2 PWP2, small subunit processome component increases expression ISO Benztropine results in increased expression of PWP2 protein CTD PMID:34122009 NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Benztropine results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Benztropine results in decreased expression of QDPR protein CTD PMID:34122009 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Benztropine results in decreased expression of RACK1 protein CTD PMID:34122009 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rbm15 RNA binding motif protein 15 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RBM15 protein CTD PMID:34122009 NCBI chr 2:194,945,717...194,954,523
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RIC8A protein CTD PMID:34122009 NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467 		JBrowse link
G Rpl10a ribosomal protein L10A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL10A protein CTD PMID:34122009 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357 		JBrowse link
G Rpl19 ribosomal protein L19 increases expression ISO Benztropine results in increased expression of RPL19 protein CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112 		JBrowse link
G Rpl24 ribosomal protein L24 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL24 protein CTD PMID:34122009 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370 		JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Benztropine results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,470...65,651,363
Ensembl chr10:36,831,500...36,831,990
Ensembl chr 7:36,831,500...36,831,990
Ensembl chr10:36,831,500...36,831,990 		JBrowse link
G Rpl7a ribosomal protein L7A decreases expression ISO Benztropine results in decreased expression of RPL7A protein CTD PMID:34122009 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPLP1 protein CTD PMID:34122009 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339 		JBrowse link
G Rps12 ribosomal protein S12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS12 protein CTD PMID:34122009 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps18 ribosomal protein S18 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein CTD PMID:34122009 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Benztropine results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rps27a ribosomal protein S27a increases expression ISO Benztropine results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011 		JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Benztropine results in decreased expression of RPS3 protein CTD PMID:34122009 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 increases expression ISO Benztropine results in increased expression of RUVBL2 protein CTD PMID:34122009 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SAE1 protein CTD PMID:34122009 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Benztropine results in decreased expression of SARS protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Satb2 SATB homeobox 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression ISO Benztropine results in decreased expression of SCCPDH protein CTD PMID:34122009 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222 		JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Benztropine results in decreased expression of SDCBP protein CTD PMID:34122009 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SEC23A protein CTD PMID:34122009 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035 		JBrowse link
G Sec61b SEC61 translocon subunit beta increases expression ISO Benztropine results in increased expression of SEC61B protein CTD PMID:34122009 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804 		JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Benztropine results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055 		JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SERBP1 protein CTD PMID:34122009 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813 		JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Benztropine results in increased expression of SERPINB4 protein CTD PMID:34122009 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985 		JBrowse link
G Sf1 splicing factor 1 decreases expression ISO Benztropine results in decreased expression of SF1 protein CTD PMID:34122009 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 decreases expression ISO Benztropine results in decreased expression of SF3B3 protein CTD PMID:34122009 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sgca sarcoglycan, alpha decreases expression ISO Benztropine results in decreased expression of SGCA protein CTD PMID:34122009 NCBI chr10:79,904,698...79,922,813
Ensembl chr10:79,908,738...79,922,813 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SHMT1 protein CTD PMID:34122009 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc25a6 solute carrier family 25 member 6 increases expression ISO Benztropine results in increased expression of SLC25A6 protein CTD PMID:34122009 NCBI chr18:68,571,229...68,572,474
Ensembl chr18:68,571,300...68,572,199 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Benztropine results in decreased expression of SLC2A1 protein CTD PMID:34122009 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC38A2 protein CTD PMID:34122009 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC3A2 protein CTD PMID:34122009 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Benztropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 decreases expression ISO Benztropine results in decreased expression of SMARCB1 protein CTD PMID:34122009 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMC3 protein CTD PMID:34122009 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMU1 protein CTD PMID:34122009 NCBI chr 5:55,856,691...55,875,262
Ensembl chr 5:55,856,246...55,875,300 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SNRNP200 protein
Benztropine results in increased expression of SNRNP200 protein		 CTD PMID:34122009 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Benztropine results in increased expression of SNRPA protein CTD PMID:34122009 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Benztropine results in increased expression of SNRPD2 protein CTD PMID:34122009 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Srek1 splicing regulatory glutamic acid and lysine rich protein 1 decreases expression ISO Benztropine results in decreased expression of SREK1 protein CTD PMID:34122009 NCBI chr 2:34,849,552...34,885,120
Ensembl chr 2:34,852,458...34,884,972 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO Benztropine results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stim1 stromal interaction molecule 1 decreases expression ISO Benztropine results in decreased expression of STIM1 protein CTD PMID:34122009 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Benztropine results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression ISO Benztropine results in decreased expression of STRAP protein CTD PMID:34122009 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of STUB1 protein CTD PMID:34122009 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Benztropine results in decreased expression of SUCLG1 protein CTD PMID:34122009 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 decreases expression ISO Benztropine results in decreased expression of SUMO2 protein CTD PMID:34122009 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SUN1 protein CTD PMID:34122009 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Benztropine results in decreased expression of SYNCRIP protein CTD PMID:34122009 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515 		JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Benztropine results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Tbcb tubulin folding cofactor B decreases expression ISO Benztropine results in decreased expression of TBCB protein CTD PMID:34122009 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TCAF1 protein
Benztropine results in decreased expression of TCAF1 protein		 CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,309
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164 		JBrowse link
G Tln2 talin 2 decreases expression ISO Benztropine results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,223
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tmpo thymopoietin decreases expression ISO Benztropine results in decreased expression of TMPO protein CTD PMID:34122009 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TNKS1BP1 protein
Benztropine results in decreased expression of TNKS1BP1 protein		 CTD PMID:34122009 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038 		JBrowse link
G Tomm34 translocase of outer mitochondrial membrane 34 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of TOMM34 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TOMM34 protein		 CTD PMID:34122009 NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373 		JBrowse link
G Top1mt DNA topoisomerase I mitochondrial increases expression ISO Benztropine results in increased expression of TOP1MT protein CTD PMID:34122009 NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049 		JBrowse link
G Tpm2 tropomyosin 2 decreases expression ISO Benztropine results in decreased expression of TPM2 protein CTD PMID:34122009 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992 		JBrowse link
G Tpm3 tropomyosin 3 decreases expression ISO Benztropine results in decreased expression of TPM3 protein CTD PMID:34122009 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO Benztropine results in decreased expression of TPR protein CTD PMID:34122009 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of TRIM28 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TRIM28 protein		 CTD PMID:34122009 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Tspan3 tetraspanin 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TSPAN3 protein CTD PMID:34122009 NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880 		JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TTC21A protein CTD PMID:34122009 NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:119,666,933...119,702,456 		JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Benztropine results in increased expression of TTYH2 protein CTD PMID:34122009 NCBI chr10:99,708,998...99,753,451
Ensembl chr10:99,709,007...99,753,444 		JBrowse link
G Ttyh3 tweety family member 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein CTD PMID:34122009 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459 		JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Benztropine results in increased expression of TUBB protein CTD PMID:34122009 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TWF2 protein CTD PMID:34122009 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Txlna taxilin alpha decreases expression ISO Benztropine results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583 		JBrowse link
G Tyms thymidylate synthetase increases expression ISO Benztropine results in increased expression of TYMS protein CTD PMID:34122009 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 decreases expression ISO Benztropine results in decreased expression of U2AF2 protein CTD PMID:34122009 NCBI chr 1:68,760,911...68,779,730
Ensembl chr 1:68,760,924...68,778,492 		JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UBA2 protein CTD PMID:34122009 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682 		JBrowse link
G Ubap2l ubiquitin associated protein 2-like decreases expression ISO Benztropine results in decreased expression of UBAP2L protein CTD PMID:34122009 NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998 		JBrowse link
G Ubc ubiquitin C increases expression ISO Benztropine results in increased expression of UBC protein CTD PMID:34122009 NCBI chr12:31,238,889...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ubqln2 ubiquilin 2 decreases expression ISO Benztropine results in decreased expression of UBQLN2 protein CTD PMID:34122009 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UCHL1 protein CTD PMID:34122009 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Benztropine results in decreased expression of UCHL3 protein CTD PMID:34122009 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression ISO Benztropine results in decreased expression of UGDH protein CTD PMID:34122009 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Unc45b unc-45 myosin chaperone B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UNC45B protein CTD PMID:34122009 NCBI chr10:67,845,382...67,873,389
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of UQCRC2 protein CTD PMID:34122009 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453 		JBrowse link
G Uso1 USO1 vesicle transport factor decreases expression ISO Benztropine results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of USP10 protein CTD PMID:34122009 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression ISO Benztropine results in increased expression of USP14 protein CTD PMID:34122009 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
G Utp18 UTP18 small subunit processome component increases expression ISO Benztropine results in increased expression of UTP18 protein CTD PMID:34122009 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression ISO Benztropine results in decreased expression of VASP protein CTD PMID:34122009 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Benztropine results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 9:61,475,498...61,502,584
Ensembl chr 9:61,475,517...61,502,469 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Benztropine results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091 		JBrowse link
G Xpo7 exportin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of XPO7 protein CTD PMID:34122009 NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Benztropine results in increased expression of YWHAQ protein CTD PMID:34122009 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ZBTB42 protein CTD PMID:34122009 NCBI chr 6:131,734,257...131,742,459
Ensembl chr 6:131,738,356...131,742,685 		JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Benztropine results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322 		JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Benztropine results in decreased expression of ZKSCAN7 protein CTD PMID:34122009 NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:122,502,218...122,519,600 		JBrowse link
biperiden term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Biperiden results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Biperiden results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions EXP Biperiden binds to and results in decreased activity of CHRM1 protein CTD PMID:21336581 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Ereg epiregulin increases expression ISO Biperiden results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Biperiden results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Biperiden results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression ISO Biperiden results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Biperiden results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Biperiden results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Biperiden results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
bromocriptine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions		 EXP Bromocriptine results in increased expression of ABCB1 protein
Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]		 CTD PMID:9111066 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases activity
increases expression
multiple interactions		 EXP Bromocriptine results in increased activity of ABCB1B promoter
Bromocriptine results in increased expression of ABCB1B mRNA
Clozapine inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; eticlopride inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Pertussis Toxin inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]		 CTD PMID:9111066 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
multiple interactions		 EXP Bromocriptine results in increased expression of AKR1C3 mRNA
methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA]		 CTD PMID:21427058 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Bromocriptine results in increased expression of ATF3 mRNA; Bromocriptine results in increased expression of ATF3 protein CTD PMID:21867702 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP Bromocriptine results in increased expression of BAX protein
[Bromocriptine co-treated with Octreotide] results in increased expression of BAX protein		 CTD PMID:15046398 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases secretion ISO Bromocriptine results in decreased secretion of BDNF protein CTD PMID:12770616 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Bromocriptine co-treated with Estradiol] results in decreased expression of CTNNB1 protein CTD PMID:11786374 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 EXP Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of CYP11A1 mRNA]
Bromocriptine results in decreased expression of CYP11A1 protein		 CTD PMID:12742521 PMID:21427058 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Bromocriptine results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Bromocriptine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
affects binding		 ISO CYP3A4 protein affects the metabolism of Bromocriptine
Bromocriptine inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
Bromocriptine binds to CYP3A4 protein		 CTD PMID:15286053 PMID:17198380 PMID:19299527 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity ISO Bromocriptine results in decreased activity of DBH protein CTD PMID:501350 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression
multiple interactions
increases expression
increases response to substance
affects expression
affects response to substance		 EXP
ISO		 Bromocriptine results in decreased expression of DRD2 mRNA
[Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA
Bromocriptine results in increased expression of DRD2 mRNA
DRD2 polymorphism results in increased susceptibility to Bromocriptine
Bromocriptine affects the expression of DRD2 mRNA
DRD2 protein affects the susceptibility to Bromocriptine
Bromocriptine binds to and results in increased activity of DRD2 mRNA; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA]		 CTD PMID:1534540 PMID:8103596 PMID:15781964 PMID:16901644 PMID:20063113 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions
decreases expression		 EXP [1-Methyl-4-phenylpyridinium co-treated with Bromocriptine] results in decreased expression of DRD3 mRNA
Bromocriptine results in decreased expression of DRD3 mRNA		 CTD PMID:17000468 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Bromocriptine co-treated with Estradiol] results in increased expression of ESR1 protein CTD PMID:11786374 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Bromocriptine results in increased expression of FSHB protein CTD PMID:86031 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression
decreases secretion		 ISO Bromocriptine results in decreased expression of GDNF mRNA
Bromocriptine results in decreased secretion of GDNF protein		 CTD PMID:12770616 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gh1 growth hormone 1 decreases expression
increases expression		 ISO Bromocriptine results in decreased expression of GH1 protein
Bromocriptine results in increased expression of GH1 protein		 CTD PMID:772175 PMID:3226523 PMID:3745407 PMID:7293648 PMID:19420816 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Bromocriptine results in increased expression of HMOX1 mRNA; Bromocriptine results in increased expression of HMOX1 protein CTD PMID:21867702 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Bromocriptine binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ins2 insulin 2 decreases expression ISO Bromocriptine results in decreased expression of INS protein CTD PMID:16803851 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression ISO Bromocriptine results in increased expression of LHB protein CTD PMID:86031 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK1 protein] CTD PMID:19595700 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK3 protein] CTD PMID:19595700 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases localization ISO Bromocriptine results in increased localization of NFE2L2 protein CTD PMID:21867702 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor increases secretion ISO Bromocriptine results in increased secretion of NGF protein CTD PMID:12770616 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein] CTD PMID:21867702 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions EXP Bromocriptine affects the reaction [methyl cellosolve results in increased expression of NR5A2 mRNA] CTD PMID:21427058 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein] CTD PMID:15677882 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pomc proopiomelanocortin decreases expression
increases expression
multiple interactions		 EXP
ISO		 Bromocriptine results in decreased expression of POMC protein alternative form
Bromocriptine results in increased expression of POMC mRNA; Bromocriptine results in increased expression of POMC protein modified form
Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone]		 CTD PMID:1325994 PMID:6274577 PMID:12742521 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
affects localization		 EXP Bromocriptine promotes the reaction [Estrogens results in increased expression of and results in increased cleavage of PRKCD protein]
Bromocriptine affects the localization of PRKCD protein		 CTD PMID:19595700 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prl prolactin multiple interactions
decreases expression
decreases secretion		 ISO
EXP		 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Nalorphine results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
Bromocriptine results in decreased expression of PRL protein
Bromocriptine results in decreased secretion of PRL protein
Bromocriptine inhibits the reaction [Amisulpride results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Estradiol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of PRL protein]; Estradiol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Ethanol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]		 CTD PMID:86031 PMID:86795 PMID:90217 PMID:1407345 PMID:1874184 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions EXP Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of SCARB1 mRNA] CTD PMID:21427058 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein] CTD PMID:21867702 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Bromocriptine results in decreased expression of STAR protein CTD PMID:12742521 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A affects localization ISO Bromocriptine affects the localization of STAT5A protein CTD PMID:17884938 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions EXP Bromocriptine inhibits the reaction [Estradiol results in increased expression of TGFA mRNA] CTD PMID:1534540 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of TGFB1 protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of TGFB1 protein] CTD PMID:15677882 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein]
Bromocriptine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:11752888 PMID:21867702 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VEGFA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of VEGFA protein] CTD PMID:15677882 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vip vasoactive intestinal peptide multiple interactions ISO
EXP		 Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
[Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]		 CTD PMID:6441721 PMID:15677882 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
cabergoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression ISO Cabergoline results in increased expression of BDNF protein CTD PMID:35104500 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO Cabergoline results in increased expression of CREB1 protein modified form CTD PMID:35104500 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO Cabergoline binds to and results in increased activity of DRD2 protein CTD PMID:35104500 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression
increases secretion		 ISO cabergoline results in increased expression of GDNF mRNA
cabergoline results in increased secretion of GDNF protein		 CTD PMID:12770616 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ngf nerve growth factor increases expression
increases secretion		 ISO cabergoline results in increased expression of NGF mRNA
cabergoline results in increased secretion of NGF protein		 CTD PMID:12770616 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Prl prolactin decreases expression
multiple interactions
decreases secretion		 ISO
EXP		 cabergoline results in decreased expression of PRL protein
Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [cabergoline results in decreased secretion of PRL protein]		 CTD PMID:2570719 PMID:3745407 PMID:7670571 PMID:15377706 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
carbidopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of BAX protein]		 CTD PMID:34560070 PMID:35202708 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Carbidopa inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]		 CTD PMID:34560070 PMID:35202708 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]		 CTD PMID:34560070 PMID:35202708 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]		 CTD PMID:34560070 PMID:35202708 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO
EXP		 COMT protein results in increased methylation of Carbidopa CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of DDC mRNA]
Carbidopa binds to and results in decreased activity of DDC protein		 CTD PMID:35151785 PMID:35202708 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]] CTD PMID:35202708 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]] CTD PMID:35202708 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]] CTD PMID:35202708 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of IL1B protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]		 CTD PMID:34560070 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of MAOA protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of MAOA protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]]		 CTD PMID:34560070 PMID:35202708 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]] CTD PMID:35202708 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]] CTD PMID:35202708 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b multiple interactions ISO Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]] CTD PMID:35202708 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]] CTD PMID:35202708 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] CTD PMID:34560070 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of TNF protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of TNF protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of TNF protein]		 CTD PMID:34560070 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of TPH1 mRNA]; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of TPH1 protein] CTD PMID:35202708 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
carbinoxamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO carbinoxamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO carbinoxamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
dimenhydrinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Dimenhydrinate results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dimenhydrinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
diphenhydramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Diphenhydramine CTD PMID:22310178 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity		 ISO Protons affects the reaction [Diphenhydramine results in decreased activity of BCHE protein] CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Diphenhydramine results in decreased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Ereg epiregulin decreases expression ISO Diphenhydramine results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of F3] CTD PMID:16009787 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Gnai1 G protein subunit alpha i1 increases response to substance ISO GNAI1 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases response to substance ISO GNAI2 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO
EXP		 Diphenhydramine binds to and results in decreased activity of HRH1 protein; Diphenhydramine binds to and results in increased activity of HRH1 protein; Diphenhydramine inhibits the reaction [Pyrilamine binds to HRH1 protein]; HRH1 protein promotes the reaction [Diphenhydramine results in decreased susceptibility to CXCL8 protein]
[Diphenhydramine results in decreased activity of HRH1 protein] which results in decreased susceptibility to Erythromycin		 CTD PMID:1912125 PMID:2419744 PMID:2461127 PMID:7522859 PMID:9609743 More... NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression		 ISO Diphenhydramine results in increased expression of IL1B mRNA
Diphenhydramine results in decreased expression of IL1B mRNA		 CTD PMID:28138970 PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 decreases expression ISO Diphenhydramine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of IL6 protein] CTD PMID:11336536 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Diphenhydramine co-treated with PK 11195] binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of PLA2G4A mRNA] CTD PMID:9609743 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Diphenhydramine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Diphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine] CTD PMID:19821448 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Diphenhydramine results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Diphenhydramine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
entacapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox3 acyl-CoA oxidase 3, pristanoyl affects binding EXP entacapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding EXP entacapone binds to ACSL1 protein CTD PMID:19783845 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding EXP entacapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr16:76,283,199...76,298,614
NCBI chr16:76,298,777...76,315,075
Ensembl chr16:76,283,103...76,354,440 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase affects binding EXP entacapone binds to AUH protein CTD PMID:19783845 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896 		JBrowse link
G Cltc clathrin heavy chain affects binding EXP entacapone binds to CLTC protein CTD PMID:19783845 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Comt catechol-O-methyltransferase decreases activity
affects binding
multiple interactions		 ISO
EXP		 entacapone results in decreased activity of COMT protein
entacapone binds to COMT protein
[entacapone results in decreased activity of COMT protein] which results in increased abundance of Dopamine; entacapone inhibits the reaction [COMT protein results in increased methylation of Levodopa]		 CTD PMID:12898346 PMID:15566291 PMID:19783845 PMID:20334432 PMID:23206800 More... NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects binding EXP entacapone binds to ECHS1 protein CTD PMID:19783845 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Ereg epiregulin increases expression ISO entacapone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO entacapone results in decreased expression of GPAM protein CTD PMID:29688484 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP entacapone binds to HBB protein CTD PMID:19783845 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects binding EXP entacapone binds to HSD17B13 protein CTD PMID:19783845 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects binding EXP entacapone binds to HSD17B4 protein CTD PMID:19783845 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO entacapone results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO entacapone results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO entacapone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Pc pyruvate carboxylase affects binding EXP entacapone binds to PC protein CTD PMID:19783845 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression ISO entacapone results in decreased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO entacapone results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO entacapone results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO entacapone results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Snca synuclein alpha multiple interactions ISO entacapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding EXP entacapone binds to SULT2A1 protein CTD PMID:19783845 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO entacapone results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation
decreases glucuronidation		 ISO UGT1A9 protein results in increased glucuronidation of entacapone
UGT1A9 protein mutant form results in decreased glucuronidation of entacapone		 CTD PMID:15044611 PMID:15802387 PMID:16344532 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
lisuride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Lisuride binds to and results in decreased activity of ADRA1A protein; Lisuride promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Lisuride binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ifng interferon gamma increases expression ISO Lisuride results in increased expression of IFNG CTD PMID:7948314 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Prl prolactin multiple interactions
decreases secretion		 ISO
EXP		 Lisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein]; Lisuride results in decreased expression of and results in decreased secretion of PRL protein
Lisuride analog results in decreased secretion of PRL protein; Lisuride results in decreased secretion of PRL protein		 CTD PMID:386688 PMID:6492995 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Lisuride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
memantine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP asoxime chloride inhibits the reaction [Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein] CTD PMID:2241428 PMID:30682440 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] CTD PMID:21290839 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in decreased expression of ARC protein] CTD PMID:34474083 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression ISO Memantine affects the expression of BAX protein CTD PMID:29226720 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 EXP
ISO		 Memantine analog inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; Memantine inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]
Memantine results in decreased expression of BCL2 protein		 CTD PMID:29226720 PMID:32092300 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Memantine results in decreased expression of BIRC5 protein CTD PMID:29226720 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein] CTD PMID:24333387 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Capn1 calpain 1 multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of CAPN1 protein] CTD PMID:34474083 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein] CTD PMID:34474083 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO
EXP		 Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP3 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [salsolinol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Memantine results in increased expression of CASP3 protein
Memantine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CASP3 protein]
Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]		 CTD PMID:17996985 PMID:19959636 PMID:20347921 PMID:24333387 PMID:29226720 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP7 protein] CTD PMID:19959636 PMID:20347921 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 increases expression ISO Memantine results in increased expression of CASP9 protein CTD PMID:29226720 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Memantine results in decreased expression of CCND1 protein CTD PMID:29226720 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO Memantine results in increased expression of CDK4 protein CTD PMID:29226720 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein] CTD PMID:23562514 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions EXP
ISO		 Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]
Memantine inhibits the reaction [Lipopolysaccharides results in decreased expression of DLG4 protein]		 CTD PMID:24333387 PMID:34474083 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP
ISO		 Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]		 CTD PMID:24333387 PMID:34474083 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GRIN2B protein] CTD PMID:34474083 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein]]; Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:32092300 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:34474083 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein] CTD PMID:24333387 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein] CTD PMID:23562514 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein] CTD PMID:23562514 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Memantine results in decreased expression of MYC protein CTD PMID:29226720 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Memantine inhibits the reaction [N-Methylaspartate results in decreased expression of NEFL mRNA]; Memantine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:34474083 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Penk proenkephalin multiple interactions EXP Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] CTD PMID:14642644 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA protein CTD PMID:33069748 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Memantine results in increased expression of PRKCG mRNA CTD PMID:11169168 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]
Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:24333387 PMID:34474083 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
mesulergine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2b 5-hydroxytryptamine receptor 2B affects binding
multiple interactions		 ISO mesulergine binds to HTR2B protein
Fluoxetine promotes the reaction [mesulergine binds to HTR2B protein]		 CTD PMID:11930908 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
affects binding		 EXP
ISO		 Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Carbamazepine inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]; Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]; Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]; Plant Extracts inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Plant Extracts inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein]		 CTD PMID:18083778 PMID:19439326 PMID:19700373 PMID:29458138 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions
affects binding		 ISO [mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; mesulergine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]
mesulergine binds to HTR7 protein		 CTD PMID:14578406 PMID:20827463 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Prl prolactin multiple interactions EXP mesulergine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:1421203 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
orphenadrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin affects expression EXP Orphenadrine affects the expression of A2M mRNA CTD PMID:23665939 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects expression EXP Orphenadrine affects the expression of ABCB1B mRNA CTD PMID:23665939 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA CTD PMID:23665939 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Orphenadrine affects the expression of ABCC3 mRNA CTD PMID:23665939 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 affects expression EXP Orphenadrine affects the expression of ABCD2 mRNA CTD PMID:23665939 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression EXP Orphenadrine affects the expression of ABLIM3 mRNA CTD PMID:23665939 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 affects expression EXP Orphenadrine affects the expression of ACE2 mRNA CTD PMID:23665939 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acer3 alkaline ceramidase 3 affects expression EXP Orphenadrine affects the expression of ACER3 mRNA CTD PMID:23665939 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Orphenadrine affects the expression of ACSL5 mRNA CTD PMID:23665939 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 affects expression EXP Orphenadrine affects the expression of ACSM3 mRNA CTD PMID:23665939 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 affects expression EXP Orphenadrine affects the expression of ADGRG2 mRNA CTD PMID:23665939 NCBI chr  X:34,297,402...34,422,590
Ensembl chr  X:34,297,402...34,422,609 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 affects expression EXP Orphenadrine affects the expression of ADGRV1 mRNA CTD PMID:23665939 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Orphenadrine affects the expression of ADH4 mRNA CTD PMID:23665939 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adora1 adenosine A1 receptor affects expression EXP Orphenadrine affects the expression of ADORA1 mRNA CTD PMID:23665939 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adora2a adenosine A2a receptor affects expression EXP Orphenadrine affects the expression of ADORA2A mRNA CTD PMID:23665939 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression EXP Orphenadrine affects the expression of ADRB2 mRNA CTD PMID:23665939 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Ajuba ajuba LIM protein affects expression EXP Orphenadrine affects the expression of JUB mRNA CTD PMID:23665939 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Orphenadrine affects the expression of AKR7A3 mRNA CTD PMID:23665939 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Orphenadrine affects the expression of ALDH1A1 mRNA CTD PMID:23665939 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated affects expression EXP Orphenadrine affects the expression of ALPL mRNA CTD PMID:23665939 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Als2cl ALS2 C-terminal like affects expression EXP Orphenadrine affects the expression of ALS2CL mRNA CTD PMID:23665939 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419 		JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Orphenadrine affects the expression of AMIGO3 mRNA CTD PMID:23665939 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555 		JBrowse link
G Amotl2 angiomotin like 2 affects expression EXP Orphenadrine affects the expression of AMOTL2 mRNA CTD PMID:23665939 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Orphenadrine affects the expression of ANGPTL4 mRNA CTD PMID:23665939 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Angptl6 angiopoietin-like 6 affects expression EXP Orphenadrine affects the expression of ANGPTL6 mRNA CTD PMID:23665939 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925 		JBrowse link
G Ankrd9 ankyrin repeat domain 9 affects expression EXP Orphenadrine affects the expression of ANKRD9 mRNA CTD PMID:23665939 NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923 		JBrowse link
G Ano1 anoctamin 1 affects expression EXP Orphenadrine affects the expression of ANO1 mRNA CTD PMID:23665939 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069 		JBrowse link
G Anxa5 annexin A5 affects expression EXP Orphenadrine affects the expression of ANXA5 mRNA CTD PMID:23665939 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G App amyloid beta precursor protein affects expression EXP Orphenadrine affects the expression of APP mRNA CTD PMID:23665939 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp9 aquaporin 9 affects expression EXP Orphenadrine affects the expression of AQP9 mRNA CTD PMID:23665939 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arhgap10 Rho GTPase activating protein 10 affects expression EXP Orphenadrine affects the expression of ARHGAP10 mRNA CTD PMID:23665939 NCBI chr19:30,448,572...30,710,315
Ensembl chr19:30,448,637...30,710,313 		JBrowse link
G Arhgap22 Rho GTPase activating protein 22 affects expression EXP Orphenadrine affects the expression of ARHGAP22 mRNA CTD PMID:23665939 NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression EXP Orphenadrine affects the expression of ARHGEF10 mRNA CTD PMID:23665939 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor 15 affects expression EXP Orphenadrine affects the expression of ARHGEF15 mRNA CTD PMID:23665939 NCBI chr10:53,650,521...53,662,914
Ensembl chr10:53,650,553...53,663,913 		JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 affects expression EXP Orphenadrine affects the expression of ARMCX1 mRNA CTD PMID:23665939 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299 		JBrowse link
G Arrdc2 arrestin domain containing 2 affects expression EXP Orphenadrine affects the expression of ARRDC2 mRNA CTD PMID:23665939 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029 		JBrowse link
G Atf3 activating transcription factor 3 affects expression EXP Orphenadrine affects the expression of ATF3 mRNA CTD PMID:23665939 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 affects expression EXP Orphenadrine affects the expression of ATP2B2 mRNA CTD PMID:23665939 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atrnl1 attractin like 1 affects expression EXP Orphenadrine affects the expression of ATRNL1 mRNA CTD PMID:23665939 NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197 		JBrowse link
G Azin2 antizyme inhibitor 2 affects expression EXP Orphenadrine affects the expression of AZIN2 mRNA CTD PMID:23665939 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397 		JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 affects expression EXP Orphenadrine affects the expression of B3GNT9 mRNA CTD PMID:23665939 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 affects expression EXP Orphenadrine affects the expression of B4GALT6 mRNA CTD PMID:23665939 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Orphenadrine affects the expression of BAMBI mRNA CTD PMID:23665939 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bbc3 Bcl-2 binding component 3 affects expression EXP Orphenadrine affects the expression of BBC3 mRNA CTD PMID:23665939 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl6 BCL6, transcription repressor affects expression EXP Orphenadrine affects the expression of BCL6 mRNA CTD PMID:23665939 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bco2 beta-carotene oxygenase 2 affects expression EXP Orphenadrine affects the expression of BCO2 mRNA CTD PMID:23665939 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 affects expression EXP Orphenadrine affects the expression of BHLHA15 mRNA CTD PMID:23665939 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Bicc1 BicC family RNA binding protein 1 affects expression EXP Orphenadrine affects the expression of BICC1 mRNA CTD PMID:23665939 NCBI chr20:17,449,644...17,686,775
Ensembl chr20:17,449,560...17,686,776 		JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression EXP Orphenadrine affects the expression of BMP4 mRNA CTD PMID:23665939 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Btbd7 BTB domain containing 7 affects expression EXP Orphenadrine affects the expression of BTBD7 mRNA CTD PMID:23665939 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G C1qtnf2 C1q and TNF related 2 affects expression EXP Orphenadrine affects the expression of C1QTNF2 mRNA CTD PMID:23665939 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185 		JBrowse link
G C8h15orf39 similar to human chromosome 15 open reading frame 39 affects expression EXP Orphenadrine affects the expression of C8H15ORF39 mRNA CTD PMID:23665939 NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941 		JBrowse link
G Calcrl calcitonin receptor like receptor affects expression EXP Orphenadrine affects the expression of CALCRL mRNA CTD PMID:23665939 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Car1 carbonic anhydrase 1 affects expression EXP Orphenadrine affects the expression of CA1 mRNA CTD PMID:23665939 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Orphenadrine affects the expression of CA2 mRNA CTD PMID:23665939 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 affects expression EXP Orphenadrine affects the expression of CA3 mRNA CTD PMID:23665939 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Card19 caspase recruitment domain family, member 19 affects expression EXP Orphenadrine affects the expression of CARD19 mRNA CTD PMID:23665939 NCBI chr17:15,432,572...15,445,318
Ensembl chr17:15,432,612...15,445,318 		JBrowse link
G Casp2 caspase 2 affects expression EXP Orphenadrine affects the expression of CASP2 mRNA CTD PMID:23665939 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Cblc Cbl proto-oncogene C affects expression EXP Orphenadrine affects the expression of CBLC mRNA CTD PMID:23665939 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755 		JBrowse link
G Cbx4 chromobox 4 affects expression EXP Orphenadrine affects the expression of CBX4 mRNA CTD PMID:23665939 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706 		JBrowse link
G Ccdc68 coiled-coil domain containing 68 affects expression EXP Orphenadrine affects the expression of CCDC68 mRNA CTD PMID:23665939 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119 		JBrowse link
G Ccn1 cellular communication network factor 1 affects expression EXP Orphenadrine affects the expression of CCN1 mRNA CTD PMID:23665939 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Orphenadrine promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:23665939 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 affects expression EXP Orphenadrine affects the expression of CCND2 mRNA CTD PMID:23665939 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd24 CD24 molecule affects expression EXP Orphenadrine affects the expression of CD24 mRNA CTD PMID:23665939 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd276 Cd276 molecule affects expression EXP Orphenadrine affects the expression of CD276 mRNA CTD PMID:23665939 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd36 CD36 molecule affects expression EXP Orphenadrine affects the expression of CD36 mRNA CTD PMID:23665939 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression EXP Orphenadrine affects the expression of CDC42EP1 mRNA CTD PMID:23665939 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200 		JBrowse link
G Cdh3 cadherin 3 affects expression EXP Orphenadrine affects the expression of CDH3 mRNA CTD PMID:23665939 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 affects expression EXP Orphenadrine affects the expression of CDR2 mRNA CTD PMID:23665939 NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472 		JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Orphenadrine affects the expression of CES2 mRNA CTD PMID:23665939 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cfap68 cilia and flagella associated protein 68 affects expression EXP Orphenadrine affects the expression of CFAP68 mRNA CTD PMID:23665939 NCBI chr 8:51,107,663...51,113,192
Ensembl chr 8:51,107,721...51,113,420 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression EXP Orphenadrine affects the expression of CGREF1 mRNA CTD PMID:23665939 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Chmp4c charged multivesicular body protein 4C affects expression EXP Orphenadrine affects the expression of CHMP4C mRNA CTD PMID:23665939 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP Orphenadrine affects the expression of CIDEA mRNA CTD PMID:23665939 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cish cytokine inducible SH2-containing protein affects expression EXP Orphenadrine affects the expression of CISH mRNA CTD PMID:23665939 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 affects expression EXP Orphenadrine affects the expression of CLCF1 mRNA CTD PMID:23665939 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Cldn23 claudin 23 affects expression EXP Orphenadrine affects the expression of CLDN23 mRNA CTD PMID:23665939 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523 		JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression EXP Orphenadrine affects the expression of CNDP1 mRNA CTD PMID:23665939 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain affects expression EXP Orphenadrine affects the expression of COL4A3 mRNA CTD PMID:23665939 NCBI chr 9:83,875,958...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression EXP Orphenadrine affects the expression of CPT1B mRNA CTD PMID:23665939 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Crat carnitine O-acetyltransferase affects expression EXP Orphenadrine affects the expression of CRAT mRNA CTD PMID:23665939 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 affects expression EXP Orphenadrine affects the expression of CRLF2 mRNA CTD PMID:23665939 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642 		JBrowse link
G Cryab crystallin, alpha B affects expression EXP Orphenadrine affects the expression of CRYAB mRNA CTD PMID:23665939 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cryl1 crystallin, lambda 1 affects expression EXP Orphenadrine affects the expression of CRYL1 mRNA CTD PMID:23665939 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects expression EXP Orphenadrine affects the expression of CSMD1 mRNA CTD PMID:23665939 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 affects expression EXP Orphenadrine affects the expression of CSRNP1 mRNA CTD PMID:23665939 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Cst9l cystatin 9-like affects expression EXP Orphenadrine affects the expression of CST9L mRNA CTD PMID:23665939 NCBI chr 3:136,288,093...136,290,906
Ensembl chr 3:136,288,093...136,290,906 		JBrowse link
G Ctps1 CTP synthase 1 affects expression EXP Orphenadrine affects the expression of CTPS mRNA CTD PMID:23665939 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctrb1 chymotrypsinogen B1 affects expression EXP Orphenadrine affects the expression of CTRB mRNA CTD PMID:23665939 NCBI chr19:39,652,931...39,657,666
Ensembl chr19:39,652,933...39,657,688 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression		 EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA
Orphenadrine affects the expression of CYP1A1 mRNA		 CTD PMID:23665939 PMID:23665940 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity		 ISO
EXP		 Orphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP1A2 protein
Orphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]		 CTD PMID:9241656 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Orphenadrine affects the expression of CYP2B15 mRNA CTD PMID:23665939 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
multiple interactions		 EXP Orphenadrine affects the expression of CYP2B2 mRNA
[Orphenadrine co-treated with Phenobarbital] affects the expression of CYP2B2 mRNA		 CTD PMID:23665939 PMID:23665940 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions		 ISO Orphenadrine results in decreased activity of CYP2B6 protein
Orphenadrine inhibits the reaction [CYP2B6 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2B6 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]		 CTD PMID:9241656 PMID:12464242 PMID:15306208 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 affects expression EXP Orphenadrine affects the expression of CYP2C12 mRNA CTD PMID:23665939 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 affects expression EXP Orphenadrine affects the expression of CYP2C24 mRNA CTD PMID:23665939 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity		 ISO Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2E1 protein		 CTD PMID:9241656 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 affects expression EXP Orphenadrine affects the expression of CYP3A62 mRNA CTD PMID:23665939 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4A1 mRNA CTD PMID:23665939 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Orphenadrine affects the expression of CYP4A8 mRNA CTD PMID:23665939 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4B1 mRNA CTD PMID:23665939 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 affects expression EXP Orphenadrine affects the expression of CYP4F5 mRNA CTD PMID:23665939 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP Orphenadrine affects the expression of CYP7A1 mRNA CTD PMID:23665939 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 affects expression EXP Orphenadrine affects the expression of CYP8B1 mRNA CTD PMID:23665939 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Cystm1 cysteine-rich transmembrane module containing 1 affects expression EXP Orphenadrine affects the expression of CYSTM1 mRNA CTD PMID:23665939 NCBI chr18:27,945,862...28,013,509
Ensembl chr18:27,951,653...28,013,510 		JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 affects expression EXP Orphenadrine affects the expression of CYYR1 mRNA CTD PMID:23665939 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961 		JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 affects expression EXP Orphenadrine affects the expression of DACT2 mRNA CTD PMID:23665939 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096 		JBrowse link
G Defb36 defensin beta 36 affects expression EXP Orphenadrine affects the expression of DEFB36 mRNA CTD PMID:23665939 NCBI chr 3:141,078,001...141,086,832
Ensembl chr 3:141,086,058...141,086,728 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A affects expression EXP Orphenadrine affects the expression of DIP2A mRNA CTD PMID:23665939 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 affects expression EXP Orphenadrine affects the expression of DLL1 mRNA CTD PMID:23665939 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dnhd1 dynein heavy chain domain 1 affects expression EXP Orphenadrine affects the expression of DNHD1 mRNA CTD PMID:23665939 NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858 		JBrowse link
G Dpp6 dipeptidyl peptidase like 6 affects expression EXP Orphenadrine affects the expression of DPP6 mRNA CTD PMID:23665939 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 affects expression EXP Orphenadrine affects the expression of DRAM1 mRNA CTD PMID:23665939 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765 		JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression EXP Orphenadrine affects the expression of DUSP1 mRNA CTD PMID:23665939 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 affects expression EXP Orphenadrine affects the expression of DUSP10 mRNA CTD PMID:23665939 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp13 dual specificity phosphatase 13 affects expression EXP Orphenadrine affects the expression of DUSP13 mRNA CTD PMID:23665939 NCBI chr15:2,559,720...2,575,105
Ensembl chr15:2,533,547...2,575,539 		JBrowse link
G Dusp16 dual specificity phosphatase 16 affects expression EXP Orphenadrine affects the expression of DUSP16 mRNA CTD PMID:23665939 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp8 dual specificity phosphatase 8 affects expression EXP Orphenadrine affects the expression of DUSP8 mRNA CTD PMID:23665939 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 affects expression EXP Orphenadrine affects the expression of EEIG1 mRNA CTD PMID:23665939 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Eeig2 EEIG family member 2 affects expression EXP Orphenadrine affects the expression of EEIG2 mRNA CTD PMID:23665939 NCBI chr 2:196,608,499...196,663,371
Ensembl chr 2:196,608,499...196,663,371 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 affects expression EXP Orphenadrine affects the expression of EFEMP1 mRNA CTD PMID:23665939 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression EXP Orphenadrine affects the expression of EGLN3 mRNA CTD PMID:23665939 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766 		JBrowse link
G Egr1 early growth response 1 affects expression EXP Orphenadrine affects the expression of EGR1 mRNA CTD PMID:23665939 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 affects expression EXP Orphenadrine affects the expression of EMILIN1 mRNA CTD PMID:23665939 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Orphenadrine affects the expression of EPHA2 mRNA CTD PMID:23665939 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ephb4 EPH receptor B4 affects expression EXP Orphenadrine affects the expression of EPHB4 mRNA CTD PMID:23665939 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314 		JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 affects expression EXP Orphenadrine affects the expression of ERI2 mRNA CTD PMID:23665939 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665 		JBrowse link
G F8 coagulation factor VIII affects expression EXP Orphenadrine affects the expression of F8 mRNA CTD PMID:23665939 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857 		JBrowse link
G Fam89a family with sequence similarity 89, member A affects expression EXP Orphenadrine affects the expression of FAM89A mRNA CTD PMID:23665939 NCBI chr19:52,710,003...52,722,591
Ensembl chr19:52,710,019...52,722,631 		JBrowse link
G Fbxo27 F-box protein 27 affects expression EXP Orphenadrine affects the expression of FBXO27 mRNA CTD PMID:23665939 NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778 		JBrowse link
G Fer1l5 fer-1-like family member 5 affects expression EXP Orphenadrine affects the expression of FER1L5 mRNA CTD PMID:23665939 NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425 		JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 affects expression EXP Orphenadrine affects the expression of FGD5 mRNA CTD PMID:23665939 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 affects expression EXP Orphenadrine affects the expression of FLT1 mRNA CTD PMID:23665939 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G