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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antiparkinson drug
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Accession:CHEBI:48407 term browser browse the term
Definition:A drug used in the treatment of Parkinson's disease.
Synonyms:related_synonym: antiparkinson agent
 xref: Wikipedia:Antiparkinson


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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 multiple interactions
affects localization
ISO A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
amantadine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA CTD PMID:19211973 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO Amantadine results in increased expression of IFI27 mRNA CTD PMID:16756086 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 affects expression ISO Amantadine affects the expression of IFNAR1 mRNA CTD PMID:16756086 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Amantadine results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Amantadine results in increased expression of OAS2 mRNA CTD PMID:16756086 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Amantadine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Amantadine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1 CTD PMID:15918519 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 decreases activity ISO Amantadine analog results in decreased activity of TDP1 protein CTD PMID:29248742 NCBI chr 6:123,895,860...123,963,688
Ensembl chr 6:123,897,956...123,963,675
JBrowse link
apomorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amy2a3 amylase 2a3 multiple interactions EXP Apomorphine results in increased secretion of and results in increased activity of AMY1A protein; Atenolol inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein]; Metoclopramide inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:216,373,674...216,382,260
Ensembl chr 2:216,339,154...216,382,260
JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions
ISO Apomorphine results in increased expression of AVP protein
Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein]
CTD PMID:16575035 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A decreases expression ISO Apomorphine results in decreased expression of BMPR1A mRNA CTD PMID:25633564 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Cck cholecystokinin multiple interactions
decreases activity
EXP Naloxone inhibits the reaction [CCK protein results in decreased activity of Apomorphine] CTD PMID:3561887 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance ISO CCKBR protein affects the susceptibility to Apomorphine CTD PMID:11702094 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO Apomorphine binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
CTD PMID:8103921 PMID:15985612 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects response to substance
increases response to substance
ISO
EXP
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]
DRD2 protein affects the susceptibility to Apomorphine
DRD2 protein results in increased susceptibility to Apomorphine
CTD PMID:2571179 PMID:7520908 PMID:8103596 PMID:8103921 PMID:14639100 PMID:19497322 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 increases response to substance ISO DRD3 protein results in increased susceptibility to Apomorphine CTD PMID:19497322 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Apomorphine results in increased expression of FOS protein CTD PMID:10904129 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Apomorphine results in decreased expression of FURIN mRNA CTD PMID:25633564 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP GDNF protein affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gh1 growth hormone 1 increases secretion
increases expression
ISO Apomorphine results in increased secretion of GH1 protein
Apomorphine results in increased expression of GH1 protein
CTD PMID:993808 PMID:8889285 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases secretion
decreases expression
ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Apomorphine results in decreased secretion of HAMP protein modified form
Apomorphine results in decreased expression of HAMP mRNA
CTD PMID:25633564 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] CTD PMID:8539317 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases response to substance
multiple interactions
EXP HTR6 protein results in increased susceptibility to Apomorphine
Ro4368554 inhibits the reaction [HTR6 protein results in increased susceptibility to Apomorphine]
CTD PMID:17920665 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Apomorphine inhibits the reaction [Oxidopamine results in increased phosphorylation of JUN protein] CTD PMID:14599342 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO Apomorphine results in increased activity of ODC1 protein CTD PMID:10354516 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Penk proenkephalin multiple interactions EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] CTD PMID:17719177 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Prl prolactin decreases expression ISO Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Pvalb parvalbumin affects expression EXP Apomorphine affects the expression of PVALB protein CTD PMID:15238432 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Apomorphine CTD PMID:15728856 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188
JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions EXP SHH protein modified form affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:17719177 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
benserazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO
EXP
COMT protein results in increased methylation of Benserazide CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [Oxidopamine co-treated with levodopa methyl ester] promotes the reaction [Benserazide results in increased expression of DRD1 protein] CTD PMID:19399396 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP [Oxidopamine co-treated with levodopa methyl ester] inhibits the reaction [Benserazide results in increased expression of DRD2 protein] CTD PMID:19399396 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
benzatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Benztropine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benztropine results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Benztropine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benztropine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Benztropine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Benztropine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Benztropine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Benztropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
biperiden term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Biperiden results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Biperiden results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions EXP Biperiden binds to and results in decreased activity of CHRM1 protein CTD PMID:21336581 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Ereg epiregulin increases expression ISO Biperiden results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Biperiden results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Biperiden results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Biperiden results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Biperiden results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Biperiden results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Biperiden results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
bromocriptine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
EXP Bromocriptine results in increased expression of ABCB1 protein
Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]
CTD PMID:9111066 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases activity
increases expression
multiple interactions
EXP Bromocriptine results in increased activity of ABCB1B promoter
Bromocriptine results in increased expression of ABCB1B mRNA
Clozapine inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; eticlopride inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Pertussis Toxin inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]
CTD PMID:9111066 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
multiple interactions
EXP Bromocriptine results in increased expression of AKR1C3 mRNA
methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA]
CTD PMID:21427058 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Bromocriptine results in increased expression of ATF3 mRNA; Bromocriptine results in increased expression of ATF3 protein CTD PMID:21867702 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP Bromocriptine results in increased expression of BAX protein
[Bromocriptine co-treated with Octreotide] results in increased expression of BAX protein
CTD PMID:15046398 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases secretion ISO Bromocriptine results in decreased secretion of BDNF protein CTD PMID:12770616 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Bromocriptine co-treated with Estradiol] results in decreased expression of CTNNB1 protein CTD PMID:11786374 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of CYP11A1 mRNA]
Bromocriptine results in decreased expression of CYP11A1 protein
CTD PMID:12742521 PMID:21427058 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 affects binding
affects metabolic processing
multiple interactions
ISO Bromocriptine binds to CYP3A4 protein
CYP3A4 protein affects the metabolism of Bromocriptine
Bromocriptine inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
CTD PMID:15286053 PMID:17198380 PMID:19299527 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity ISO Bromocriptine results in decreased activity of DBH protein CTD PMID:501350 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Drd2 dopamine receptor D2 affects expression
affects response to substance
multiple interactions
decreases expression
increases expression
increases response to substance
ISO
EXP
Bromocriptine affects the expression of DRD2 mRNA
DRD2 protein affects the susceptibility to Bromocriptine
Bromocriptine binds to and results in increased activity of DRD2 mRNA; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA]
Bromocriptine results in decreased expression of DRD2 mRNA
[Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA
Bromocriptine results in increased expression of DRD2 mRNA
DRD2 polymorphism results in increased susceptibility to Bromocriptine
CTD PMID:1534540 PMID:8103596 PMID:15781964 PMID:16901644 PMID:20063113 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions
decreases expression
EXP [1-Methyl-4-phenylpyridinium co-treated with Bromocriptine] results in decreased expression of DRD3 mRNA
Bromocriptine results in decreased expression of DRD3 mRNA
CTD PMID:17000468 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Bromocriptine co-treated with Estradiol] results in increased expression of ESR1 protein CTD PMID:11786374 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Bromocriptine results in increased expression of FSHB protein CTD PMID:86031 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression
decreases secretion
ISO Bromocriptine results in decreased expression of GDNF mRNA
Bromocriptine results in decreased secretion of GDNF protein
CTD PMID:12770616 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gh1 growth hormone 1 increases expression
decreases expression
ISO Bromocriptine results in increased expression of GH1 protein
Bromocriptine results in decreased expression of GH1 protein
CTD PMID:772175 PMID:3226523 PMID:3745407 PMID:7293648 PMID:19420816 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Bromocriptine results in increased expression of HMOX1 mRNA; Bromocriptine results in increased expression of HMOX1 protein CTD PMID:21867702 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Bromocriptine binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Ins2 insulin 2 decreases expression ISO Bromocriptine results in decreased expression of INS protein CTD PMID:16803851 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression ISO Bromocriptine results in increased expression of LHB protein CTD PMID:86031 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK1 protein] CTD PMID:19595700 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK3 protein] CTD PMID:19595700 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases localization ISO Bromocriptine results in increased localization of NFE2L2 protein CTD PMID:21867702 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngf nerve growth factor increases secretion ISO Bromocriptine results in increased secretion of NGF protein CTD PMID:12770616 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein] CTD PMID:21867702 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions EXP Bromocriptine affects the reaction [methyl cellosolve results in increased expression of NR5A2 mRNA] CTD PMID:21427058 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein] CTD PMID:15677882 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pomc proopiomelanocortin decreases expression
increases expression
multiple interactions
EXP
ISO
Bromocriptine results in decreased expression of POMC protein alternative form
Bromocriptine results in increased expression of POMC mRNA; Bromocriptine results in increased expression of POMC protein modified form
Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone]
CTD PMID:1325994 PMID:6274577 PMID:12742521 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
affects localization
EXP Bromocriptine promotes the reaction [Estrogens results in increased expression of and results in increased cleavage of PRKCD protein]
Bromocriptine affects the localization of PRKCD protein
CTD PMID:19595700 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prl prolactin multiple interactions
decreases secretion
decreases expression
ISO
EXP
Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Nalorphine results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
Bromocriptine results in decreased secretion of PRL protein
Bromocriptine results in decreased expression of PRL protein
Bromocriptine inhibits the reaction [Amisulpride results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Estradiol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of PRL protein]; Estradiol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Ethanol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]
CTD PMID:86031 PMID:86795 PMID:90217 PMID:1407345 PMID:1874184 PMID:2042694 PMID:2887062 PMID:3019639 PMID:3208992 PMID:3625096 PMID:3660204 PMID:3745407 PMID:3776530 PMID:4072572 PMID:6441721 PMID:6477585 PMID:6507109 PMID:6669217 PMID:6693536 PMID:6986893 PMID:7106173 PMID:7168914 PMID:7243090 PMID:7670571 PMID:8914150 PMID:11685661 PMID:11786374 PMID:12106810 PMID:12161478 PMID:12742521 PMID:12824819 PMID:15046398 PMID:15677882 PMID:21427058 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions EXP Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of SCARB1 mRNA] CTD PMID:21427058 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein] CTD PMID:21867702 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Bromocriptine results in decreased expression of STAR protein CTD PMID:12742521 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat5a signal transducer and activator of transcription 5A affects localization ISO Bromocriptine affects the localization of STAT5A protein CTD PMID:17884938 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions EXP Bromocriptine inhibits the reaction [Estradiol results in increased expression of TGFA mRNA] CTD PMID:1534540 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of TGFB1 protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of TGFB1 protein] CTD PMID:15677882 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein]
Bromocriptine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:11752888 PMID:21867702 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VEGFA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of VEGFA protein] CTD PMID:15677882 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vip vasoactive intestinal peptide multiple interactions ISO
EXP
Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
[Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]
CTD PMID:6441721 PMID:15677882 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
cabergoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor increases expression
increases secretion
ISO cabergoline results in increased expression of GDNF mRNA
cabergoline results in increased secretion of GDNF protein
CTD PMID:12770616 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Ngf nerve growth factor increases expression
increases secretion
ISO cabergoline results in increased expression of NGF mRNA
cabergoline results in increased secretion of NGF protein
CTD PMID:12770616 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Prl prolactin decreases expression
multiple interactions
decreases secretion
ISO
EXP
cabergoline results in decreased expression of PRL protein
Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [cabergoline results in decreased secretion of PRL protein]
CTD PMID:2570719 PMID:3745407 PMID:7670571 PMID:15377706 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
carbidopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO
EXP
COMT protein results in increased methylation of Carbidopa CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
carbinoxamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO carbinoxamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO carbinoxamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
dimenhydrinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Dimenhydrinate results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dimenhydrinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
diphenhydramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Diphenhydramine CTD PMID:22310178 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO Protons affects the reaction [Diphenhydramine results in decreased activity of BCHE protein] CTD PMID:236606 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Diphenhydramine results in decreased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Ereg epiregulin decreases expression ISO Diphenhydramine results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of F3] CTD PMID:16009787 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Gnai1 G protein subunit alpha i1 increases response to substance ISO GNAI1 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gnai2 G protein subunit alpha i2 increases response to substance ISO GNAI2 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions ISO
EXP
Diphenhydramine binds to and results in decreased activity of HRH1 protein; Diphenhydramine binds to and results in increased activity of HRH1 protein; Diphenhydramine inhibits the reaction [Pyrilamine binds to HRH1 protein]; HRH1 protein promotes the reaction [Diphenhydramine results in decreased susceptibility to CXCL8 protein]
[Diphenhydramine results in decreased activity of HRH1 protein] which results in decreased susceptibility to Erythromycin
CTD PMID:1912125 PMID:2419744 PMID:2461127 PMID:7522859 PMID:9609743 PMID:12856827 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
ISO Diphenhydramine results in increased expression of IL1B mRNA
Diphenhydramine results in decreased expression of IL1B mRNA
CTD PMID:28138970 PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 decreases expression ISO Diphenhydramine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of IL6 protein] CTD PMID:11336536 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Diphenhydramine co-treated with PK 11195] binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of PLA2G4A mRNA] CTD PMID:9609743 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Diphenhydramine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Diphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine] CTD PMID:19821448 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Diphenhydramine results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Diphenhydramine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
entacapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox3 acyl-CoA oxidase 3, pristanoyl affects binding EXP entacapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding EXP entacapone binds to ACSL1 protein CTD PMID:19783845 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding EXP entacapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr16:81,616,098...81,648,133
Ensembl chr16:81,616,604...81,632,030
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase affects binding EXP entacapone binds to AUH protein CTD PMID:19783845 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205
JBrowse link
G Cltc clathrin heavy chain affects binding EXP entacapone binds to CLTC protein CTD PMID:19783845 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
affects binding
multiple interactions
ISO
EXP
entacapone results in decreased activity of COMT protein
entacapone binds to COMT protein
[entacapone results in decreased activity of COMT protein] which results in increased abundance of Dopamine; entacapone inhibits the reaction [COMT protein results in increased methylation of Levodopa]
CTD PMID:12898346 PMID:15566291 PMID:19783845 PMID:20334432 PMID:23206800 PMID:29688484 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects binding EXP entacapone binds to ECHS1 protein CTD PMID:19783845 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Ereg epiregulin increases expression ISO entacapone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO entacapone results in decreased expression of GPAM protein CTD PMID:29688484 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP entacapone binds to HBB protein CTD PMID:19783845 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects binding EXP entacapone binds to HSD17B13 protein CTD PMID:19783845 NCBI chr14:7,113,544...7,128,218
Ensembl chr14:7,113,544...7,128,218
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects binding EXP entacapone binds to HSD17B4 protein CTD PMID:19783845 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO entacapone results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO entacapone results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO entacapone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pc pyruvate carboxylase affects binding EXP entacapone binds to PC protein CTD PMID:19783845 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression ISO entacapone results in decreased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO entacapone results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO entacapone results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO entacapone results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Snca synuclein alpha multiple interactions ISO entacapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding EXP entacapone binds to SULT2A1 protein CTD PMID:19783845 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO entacapone results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation
decreases glucuronidation
ISO UGT1A9 protein results in increased glucuronidation of entacapone
UGT1A9 protein mutant form results in decreased glucuronidation of entacapone
CTD PMID:15044611 PMID:15802387 PMID:16344532 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
lisuride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Lisuride binds to and results in decreased activity of ADRA1A protein; Lisuride promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Lisuride binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Ifng interferon gamma increases expression ISO Lisuride results in increased expression of IFNG CTD PMID:7948314 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Prl prolactin multiple interactions
decreases secretion
ISO
EXP
Lisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein]; Lisuride results in decreased expression of and results in decreased secretion of PRL protein
Lisuride analog results in decreased secretion of PRL protein; Lisuride results in decreased secretion of PRL protein
CTD PMID:386688 PMID:6492995 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Lisuride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
memantine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP asoxime chloride inhibits the reaction [Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein] CTD PMID:2241428 PMID:30682440 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] CTD PMID:21290839 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Memantine analog inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; Memantine inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein] CTD PMID:32092300 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein] CTD PMID:24333387 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP3 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [salsolinol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Memantine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CASP3 protein]
Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]
CTD PMID:17996985 PMID:19959636 PMID:20347921 PMID:24333387 PMID:29800586 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP7 protein] CTD PMID:19959636 PMID:20347921 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein] CTD PMID:23562514 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] CTD PMID:24333387 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr16:79,872,238...80,596,977
Ensembl chr16:79,872,323...79,973,877
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein] CTD PMID:24333387 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein]]; Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:32092300 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Itgam integrin subunit alpha M multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein] CTD PMID:24333387 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein] CTD PMID:23562514 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein] CTD PMID:23562514 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Penk proenkephalin multiple interactions EXP Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] CTD PMID:14642644 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Memantine results in increased expression of PRKCG mRNA CTD PMID:11169168 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein] CTD PMID:24333387 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
mesulergine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2b 5-hydroxytryptamine receptor 2B affects binding
multiple interactions
ISO mesulergine binds to HTR2B protein
Fluoxetine promotes the reaction [mesulergine binds to HTR2B protein]
CTD PMID:11930908 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding
multiple interactions
ISO
EXP
mesulergine binds to HTR2C protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein]
Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Carbamazepine inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]; Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]; Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]; Plant Extracts inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Plant Extracts inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]
CTD PMID:18083778 PMID:19439326 PMID:19700373 PMID:29458138 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects binding
multiple interactions
ISO mesulergine binds to HTR7 protein
[mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; mesulergine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]
CTD PMID:14578406 PMID:20827463 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Prl prolactin multiple interactions EXP mesulergine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:1421203 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
orphenadrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin affects expression EXP Orphenadrine affects the expression of A2M mRNA CTD PMID:23665939 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects expression EXP Orphenadrine affects the expression of ABCB1B mRNA CTD PMID:23665939 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA CTD PMID:23665939 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Orphenadrine affects the expression of ABCC3 mRNA CTD PMID:23665939 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 affects expression EXP Orphenadrine affects the expression of ABCD2 mRNA CTD PMID:23665939 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression EXP Orphenadrine affects the expression of ABLIM3 mRNA CTD PMID:23665939 NCBI chr18:57,126,534...57,245,965
Ensembl chr18:57,128,399...57,245,666
JBrowse link
G Ace2 angiotensin I converting enzyme 2 affects expression EXP Orphenadrine affects the expression of ACE2 mRNA CTD PMID:23665939 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acer3 alkaline ceramidase 3 affects expression EXP Orphenadrine affects the expression of ACER3 mRNA CTD PMID:23665939 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Orphenadrine affects the expression of ACSL5 mRNA CTD PMID:23665939 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 affects expression EXP Orphenadrine affects the expression of ACSM3 mRNA CTD PMID:23665939 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 affects expression EXP Orphenadrine affects the expression of ADGRG2 mRNA CTD PMID:23665939 NCBI chr  X:36,930,186...37,054,968
Ensembl chr  X:36,930,186...37,003,642
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 affects expression EXP Orphenadrine affects the expression of ADGRV1 mRNA CTD PMID:23665939 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Orphenadrine affects the expression of ADH4 mRNA CTD PMID:23665939 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adora1 adenosine A1 receptor affects expression EXP Orphenadrine affects the expression of ADORA1 mRNA CTD PMID:23665939 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor affects expression EXP Orphenadrine affects the expression of ADORA2A mRNA CTD PMID:23665939 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression EXP Orphenadrine affects the expression of ADRB2 mRNA CTD PMID:23665939 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ajuba ajuba LIM protein affects expression EXP Orphenadrine affects the expression of JUB mRNA CTD PMID:23665939 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Orphenadrine affects the expression of AKR7A3 mRNA CTD PMID:23665939 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Orphenadrine affects the expression of ALDH1A1 mRNA CTD PMID:23665939 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated affects expression EXP Orphenadrine affects the expression of ALPL mRNA CTD PMID:23665939 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Als2cl ALS2 C-terminal like affects expression EXP Orphenadrine affects the expression of ALS2CL mRNA CTD PMID:23665939 NCBI chr 8:119,156,081...119,176,680
Ensembl chr 8:119,160,731...119,174,830
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Orphenadrine affects the expression of AMIGO3 mRNA CTD PMID:23665939 NCBI chr 8:116,830,773...116,832,299 JBrowse link
G Amotl2 angiomotin like 2 affects expression EXP Orphenadrine affects the expression of AMOTL2 mRNA CTD PMID:23665939 NCBI chr 8:111,210,261...111,226,217
Ensembl chr 8:111,209,908...111,226,226
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Orphenadrine affects the expression of ANGPTL4 mRNA CTD PMID:23665939 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Angptl6 angiopoietin-like 6 affects expression EXP Orphenadrine affects the expression of ANGPTL6 mRNA CTD PMID:23665939 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Ankrd9 ankyrin repeat domain 9 affects expression EXP Orphenadrine affects the expression of ANKRD9 mRNA CTD PMID:23665939 NCBI chr 6:135,409,698...135,412,552
Ensembl chr 6:135,410,030...135,412,312
JBrowse link
G Ano1 anoctamin 1 affects expression EXP Orphenadrine affects the expression of ANO1 mRNA CTD PMID:23665939 NCBI chr 1:217,754,349...217,902,540
Ensembl chr 1:217,754,336...217,902,473
JBrowse link
G Anxa5 annexin A5 affects expression EXP Orphenadrine affects the expression of ANXA5 mRNA CTD PMID:23665939 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G App amyloid beta precursor protein affects expression EXP Orphenadrine affects the expression of APP mRNA CTD PMID:23665939 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp9 aquaporin 9 affects expression EXP Orphenadrine affects the expression of AQP9 mRNA CTD PMID:23665939 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 affects expression EXP Orphenadrine affects the expression of ARHGAP10 mRNA CTD PMID:23665939 NCBI chr19:34,138,978...34,406,593
Ensembl chr19:34,139,997...34,402,436
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 affects expression EXP Orphenadrine affects the expression of ARHGAP22 mRNA CTD PMID:23665939 NCBI chr16:9,454,269...9,613,508
Ensembl chr16:9,486,832...9,613,528
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression EXP Orphenadrine affects the expression of ARHGEF10 mRNA CTD PMID:23665939 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor 15 affects expression EXP Orphenadrine affects the expression of ARHGEF15 mRNA CTD PMID:23665939 NCBI chr10:55,532,097...55,545,675
Ensembl chr10:55,532,077...55,544,429
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 affects expression EXP Orphenadrine affects the expression of ARMCX1 mRNA CTD PMID:23665939 NCBI chr  X:105,535,670...105,539,575
Ensembl chr  X:105,537,602...105,539,375
Ensembl chr  X:105,537,602...105,539,375
JBrowse link
G Arrdc2 arrestin domain containing 2 affects expression EXP Orphenadrine affects the expression of ARRDC2 mRNA CTD PMID:23665939 NCBI chr16:20,352,480...20,356,612
Ensembl chr16:20,352,480...20,356,612
JBrowse link
G Atf3 activating transcription factor 3 affects expression EXP Orphenadrine affects the expression of ATF3 mRNA CTD PMID:23665939 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 affects expression EXP Orphenadrine affects the expression of ATP2B2 mRNA CTD PMID:23665939 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Atrnl1 attractin like 1 affects expression EXP Orphenadrine affects the expression of ATRNL1 mRNA CTD PMID:23665939 NCBI chr 1:278,546,113...279,098,977
Ensembl chr 1:278,557,792...278,815,473
JBrowse link
G Azin2 antizyme inhibitor 2 affects expression EXP Orphenadrine affects the expression of AZIN2 mRNA CTD PMID:23665939 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 affects expression EXP Orphenadrine affects the expression of B3GNT9 mRNA CTD PMID:23665939 NCBI chr19:37,208,061...37,212,400
Ensembl chr19:37,208,825...37,210,412
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 affects expression EXP Orphenadrine affects the expression of B4GALT6 mRNA CTD PMID:23665939 NCBI chr18:15,462,913...15,525,584
Ensembl chr18:15,462,913...15,525,579
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Orphenadrine affects the expression of BAMBI mRNA CTD PMID:23665939 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bbc3 Bcl-2 binding component 3 affects expression EXP Orphenadrine affects the expression of BBC3 mRNA CTD PMID:23665939 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl6 BCL6, transcription repressor affects expression EXP Orphenadrine affects the expression of BCL6 mRNA CTD PMID:23665939 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bco2 beta-carotene oxygenase 2 affects expression EXP Orphenadrine affects the expression of BCO2 mRNA CTD PMID:23665939 NCBI chr 8:54,965,577...54,990,604
Ensembl chr 8:54,965,583...54,998,864
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 affects expression EXP Orphenadrine affects the expression of BHLHA15 mRNA CTD PMID:23665939 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561
JBrowse link
G Bicc1 BicC family RNA binding protein 1 affects expression EXP Orphenadrine affects the expression of BICC1 mRNA CTD PMID:23665939 NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression EXP Orphenadrine affects the expression of BMP4 mRNA CTD PMID:23665939 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Btbd7 BTB domain containing 7 affects expression EXP Orphenadrine affects the expression of BTBD7 mRNA CTD PMID:23665939 NCBI chr 6:126,658,398...126,748,497
Ensembl chr 6:126,661,634...126,710,858
JBrowse link
G C1qtnf2 C1q and TNF related 2 affects expression EXP Orphenadrine affects the expression of C1QTNF2 mRNA CTD PMID:23665939 NCBI chr10:29,067,102...29,084,035
Ensembl chr10:29,067,102...29,084,035
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Orphenadrine affects the expression of CA3 mRNA CTD PMID:23665939 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Calcrl calcitonin receptor like receptor affects expression EXP Orphenadrine affects the expression of CALCRL mRNA CTD PMID:23665939 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Car1 carbonic anhydrase 1 affects expression EXP Orphenadrine affects the expression of CA1 mRNA CTD PMID:23665939 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Orphenadrine affects the expression of CA2 mRNA CTD PMID:23665939 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Card19 caspase recruitment domain family, member 19 affects expression EXP Orphenadrine affects the expression of CARD19 mRNA CTD PMID:23665939 NCBI chr17:15,845,920...15,858,750
Ensembl chr17:15,845,931...15,858,771
JBrowse link
G Casp2 caspase 2 affects expression EXP Orphenadrine affects the expression of CASP2 mRNA CTD PMID:23665939 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Cblc Cbl proto-oncogene C affects expression EXP Orphenadrine affects the expression of CBLC mRNA CTD PMID:23665939 NCBI chr 1:80,699,321...80,716,146
Ensembl chr 1:80,699,323...80,716,146
JBrowse link
G Cbx4 chromobox 4 affects expression EXP Orphenadrine affects the expression of CBX4 mRNA CTD PMID:23665939 NCBI chr10:108,190,947...108,196,455
Ensembl chr10:108,190,995...108,196,217
JBrowse link
G Ccdc68 coiled-coil domain containing 68 affects expression EXP Orphenadrine affects the expression of CCDC68 mRNA CTD PMID:23665939 NCBI chr18:68,408,812...68,472,323
Ensembl chr18:68,408,890...68,472,320
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression EXP Orphenadrine affects the expression of CCN1 mRNA CTD PMID:23665939 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Orphenadrine promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:23665939 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 affects expression EXP Orphenadrine affects the expression of CCND2 mRNA CTD PMID:23665939 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd24 CD24 molecule affects expression EXP Orphenadrine affects the expression of CD24 mRNA CTD PMID:23665939 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd276 Cd276 molecule affects expression EXP Orphenadrine affects the expression of CD276 mRNA CTD PMID:23665939 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
JBrowse link
G Cd36 CD36 molecule affects expression EXP Orphenadrine affects the expression of CD36 mRNA CTD PMID:23665939 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression EXP Orphenadrine affects the expression of CDC42EP1 mRNA CTD PMID:23665939 NCBI chr 7:120,063,256...120,071,154
Ensembl chr 7:120,067,379...120,071,440
JBrowse link
G Cdh3 cadherin 3 affects expression EXP Orphenadrine affects the expression of CDH3 mRNA CTD PMID:23665939 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 affects expression EXP Orphenadrine affects the expression of CDR2 mRNA CTD PMID:23665939 NCBI chr 1:190,889,698...190,914,606
Ensembl chr 1:190,889,701...190,914,610
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Orphenadrine affects the expression of CES2 mRNA CTD PMID:23665939 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression EXP Orphenadrine affects the expression of CGREF1 mRNA CTD PMID:23665939 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chmp4c charged multivesicular body protein 4C affects expression EXP Orphenadrine affects the expression of CHMP4C mRNA CTD PMID:23665939 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP Orphenadrine affects the expression of CIDEA mRNA CTD PMID:23665939 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cish cytokine inducible SH2-containing protein affects expression EXP Orphenadrine affects the expression of CISH mRNA CTD PMID:23665939 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 affects expression EXP Orphenadrine affects the expression of CLCF1 mRNA CTD PMID:23665939 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Cldn23 claudin 23 affects expression EXP Orphenadrine affects the expression of CLDN23 mRNA CTD PMID:23665939 NCBI chr16:59,988,603...59,990,327
Ensembl chr16:59,988,603...59,990,326
JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression EXP Orphenadrine affects the expression of CNDP1 mRNA CTD PMID:23665939 NCBI chr18:81,466,717...81,512,841
Ensembl chr18:81,466,716...81,499,051
JBrowse link
G Col4a3 collagen type IV alpha 3 chain affects expression EXP Orphenadrine affects the expression of COL4A3 mRNA CTD PMID:23665939 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression EXP Orphenadrine affects the expression of CPT1B mRNA CTD PMID:23665939 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Crat carnitine O-acetyltransferase affects expression EXP Orphenadrine affects the expression of CRAT mRNA CTD PMID:23665939 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crlf2 cytokine receptor-like factor 2 affects expression EXP Orphenadrine affects the expression of CRLF2 mRNA CTD PMID:23665939 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543
JBrowse link
G Cryab crystallin, alpha B affects expression EXP Orphenadrine affects the expression of CRYAB mRNA CTD PMID:23665939 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cryl1 crystallin, lambda 1 affects expression EXP Orphenadrine affects the expression of CRYL1 mRNA CTD PMID:23665939 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects expression EXP Orphenadrine affects the expression of CSMD1 mRNA CTD PMID:23665939 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 affects expression EXP Orphenadrine affects the expression of CSRNP1 mRNA CTD PMID:23665939 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Cst9l cystatin 9-like affects expression EXP Orphenadrine affects the expression of CST9L mRNA CTD PMID:23665939 NCBI chr 3:143,172,691...143,175,504
Ensembl chr 3:143,172,686...143,175,500
JBrowse link
G Ctps1 CTP synthase 1 affects expression EXP Orphenadrine affects the expression of CTPS mRNA CTD PMID:23665939 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctrb1 chymotrypsinogen B1 affects expression EXP Orphenadrine affects the expression of CTRB mRNA CTD PMID:23665939 NCBI chr19:43,906,344...43,911,020
Ensembl chr19:43,906,292...43,911,057
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA
Orphenadrine affects the expression of CYP1A1 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO
EXP
Orphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Orphenadrine results in decreased activity of CYP1A2 protein
CTD PMID:9241656 PMID:18493746 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Orphenadrine affects the expression of CYP2B15 mRNA CTD PMID:23665939 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
multiple interactions
EXP Orphenadrine affects the expression of CYP2B2 mRNA
[Orphenadrine co-treated with Phenobarbital] affects the expression of CYP2B2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2B6 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2B6 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2B6 protein
CTD PMID:9241656 PMID:12464242 PMID:15306208 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 affects expression EXP Orphenadrine affects the expression of CYP2C12 mRNA CTD PMID:23665939 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 affects expression EXP Orphenadrine affects the expression of CYP2C24 mRNA CTD PMID:23665939 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2E1 protein
CTD PMID:9241656 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 affects expression EXP Orphenadrine affects the expression of CYP3A62 mRNA CTD PMID:23665939 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4A1 mRNA CTD PMID:23665939 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Orphenadrine affects the expression of CYP4A8 mRNA CTD PMID:23665939 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression EXP Orphenadrine affects the expression of CYP4B1 mRNA CTD PMID:23665939 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 affects expression EXP Orphenadrine affects the expression of CYP4F5 mRNA CTD PMID:23665939 NCBI chr 7:14,559,806...14,574,345
Ensembl chr 7:14,529,482...14,574,361
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP Orphenadrine affects the expression of CYP7A1 mRNA CTD PMID:23665939 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 affects expression EXP Orphenadrine affects the expression of CYP8B1 mRNA CTD PMID:23665939 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cystm1 cysteine-rich transmembrane module containing 1 affects expression EXP Orphenadrine affects the expression of CYSTM1 mRNA CTD PMID:23665939 NCBI chr18:29,165,206...29,233,351
Ensembl chr18:29,191,731...29,232,978
JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 affects expression EXP Orphenadrine affects the expression of CYYR1 mRNA CTD PMID:23665939 NCBI chr11:24,967,936...25,078,740
Ensembl chr11:24,967,937...25,078,740
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 affects expression EXP Orphenadrine affects the expression of DACT2 mRNA CTD PMID:23665939 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Defb36 defensin beta 36 affects expression EXP Orphenadrine affects the expression of DEFB36 mRNA CTD PMID:23665939 NCBI chr 3:148,082,790...148,091,621
Ensembl chr 3:148,082,790...148,091,619
JBrowse link
G Dip2a disco-interacting protein 2 homolog A affects expression EXP Orphenadrine affects the expression of DIP2A mRNA CTD PMID:23665939 NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
JBrowse link
G Dll1 delta like canonical Notch ligand 1 affects expression EXP Orphenadrine affects the expression of DLL1 mRNA CTD PMID:23665939 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dnhd1 dynein heavy chain domain 1 affects expression EXP Orphenadrine affects the expression of DNHD1 mRNA CTD PMID:23665939 NCBI chr 1:170,473,792...170,570,220
Ensembl chr 1:170,471,272...170,565,063
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 affects expression EXP Orphenadrine affects the expression of DPP6 mRNA CTD PMID:23665939 NCBI chr 4:4,021,021...4,943,675
Ensembl chr 4:4,021,008...4,473,307
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 affects expression EXP Orphenadrine affects the expression of DRAM1 mRNA CTD PMID:23665939 NCBI chr 7:28,898,647...28,932,641
Ensembl chr 7:28,898,649...28,932,641
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression EXP Orphenadrine affects the expression of DUSP1 mRNA CTD PMID:23665939 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 affects expression EXP Orphenadrine affects the expression of DUSP10 mRNA CTD PMID:23665939 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp13 dual specificity phosphatase 13 affects expression EXP Orphenadrine affects the expression of DUSP13 mRNA CTD PMID:23665939 NCBI chr15:2,524,435...2,541,734
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
JBrowse link
G Dusp16 dual specificity phosphatase 16 affects expression EXP Orphenadrine affects the expression of DUSP16 mRNA CTD PMID:23665939 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Dusp8 dual specificity phosphatase 8 affects expression EXP Orphenadrine affects the expression of DUSP8 mRNA CTD PMID:23665939 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 affects expression EXP Orphenadrine affects the expression of EFEMP1 mRNA CTD PMID:23665939 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression EXP Orphenadrine affects the expression of EGLN3 mRNA CTD PMID:23665939 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Egr1 early growth response 1 affects expression EXP Orphenadrine affects the expression of EGR1 mRNA CTD PMID:23665939 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Emilin1 elastin microfibril interfacer 1 affects expression EXP Orphenadrine affects the expression of EMILIN1 mRNA CTD PMID:23665939 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Orphenadrine affects the expression of EPHA2 mRNA CTD PMID:23665939 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Ephb4 EPH receptor B4 affects expression EXP Orphenadrine affects the expression of EPHB4 mRNA CTD PMID:23665939 NCBI chr12:22,393,338...22,418,332
Ensembl chr12:22,393,330...22,417,980
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 affects expression EXP Orphenadrine affects the expression of ERI2 mRNA CTD PMID:23665939 NCBI chr 1:189,540,145...189,549,891
Ensembl chr 1:189,540,145...189,549,891
JBrowse link
G F8 coagulation factor VIII affects expression EXP Orphenadrine affects the expression of F8 mRNA CTD PMID:23665939 NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
JBrowse link
G Fam102a family with sequence similarity 102, member A affects expression EXP Orphenadrine affects the expression of FAM102A mRNA CTD PMID:23665939 NCBI chr 3:11,554,084...11,586,315
Ensembl chr 3:11,554,457...11,586,303
JBrowse link
G Fam102b family with sequence similarity 102, member B affects expression EXP Orphenadrine affects the expression of FAM102B mRNA CTD PMID:23665939 NCBI chr 2:211,762,479...211,831,837
Ensembl chr 2:211,772,128...211,831,636
JBrowse link
G Fam126a family with sequence similarity 126, member A affects expression EXP Orphenadrine affects the expression of FAM126A mRNA CTD PMID:23665939 NCBI chr 4:7,661,710...7,770,179
Ensembl chr 4:7,661,558...7,770,232
JBrowse link
G Fam89a family with sequence similarity 89, member A affects expression EXP Orphenadrine affects the expression of FAM89A mRNA CTD PMID:23665939 NCBI chr19:57,502,308...57,514,896
Ensembl chr19:57,502,308...57,514,896
JBrowse link
G Fbxo27 F-box protein 27 affects expression EXP Orphenadrine affects the expression of FBXO27 mRNA CTD PMID:23665939 NCBI chr 1:86,872,808...86,878,709 JBrowse link
G Fer1l5 fer-1-like family member 5 affects expression EXP Orphenadrine affects the expression of FER1L5 mRNA CTD PMID:23665939 NCBI chr 9:42,943,362...42,998,126
Ensembl chr 9:42,945,358...42,998,109
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 affects expression EXP Orphenadrine affects the expression of FGD5 mRNA CTD PMID:23665939 NCBI chr 4:123,865,557...123,962,904
Ensembl chr 4:123,865,725...123,962,881
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 affects expression EXP Orphenadrine affects the expression of FLT1 mRNA CTD PMID:23665939 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 affects expression EXP Orphenadrine affects the expression of FLT4 mRNA CTD PMID:23665939 NCBI chr10:35,078,782...35,120,296
Ensembl chr10:35,078,726...35,121,599
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Orphenadrine affects the expression of FMO1 mRNA CTD PMID:23665939 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Orphenadrine affects the expression of FNDC5 mRNA CTD PMID:23665939 NCBI chr 5:147,323,240...147,330,266
Ensembl chr 5:147,323,240...147,330,266
JBrowse link
G Fst follistatin affects expression EXP Orphenadrine affects the expression of FST mRNA CTD PMID:23665939 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression EXP Orphenadrine affects the expression of GADD45G mRNA CTD PMID:23665939 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gdf11 growth differentiation factor 11 affects expression EXP Orphenadrine affects the expression of GDF11 mRNA CTD PMID:23665939 NCBI chr 7:3,306,863...3,315,856
Ensembl chr 7:3,306,863...3,315,856
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 affects expression EXP Orphenadrine affects the expression of GGT1 mRNA CTD PMID:23665939 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 affects expression EXP Orphenadrine affects the expression of GIMD1 mRNA CTD PMID:23665939 NCBI chr 2:237,679,672...237,714,434
Ensembl chr 2:237,679,792...237,714,428
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 affects expression EXP Orphenadrine affects the expression of GIPC2 mRNA CTD PMID:23665939 NCBI chr 2:257,293,161...257,377,982
Ensembl chr 2:257,293,167...257,376,756
JBrowse link
G Gmip Gem-interacting protein affects expression EXP Orphenadrine affects the expression of GMIP mRNA CTD PMID:23665939 NCBI chr16:21,349,652...21,363,412
Ensembl chr16:21,349,652...21,362,955
JBrowse link
G Gna14 G protein subunit alpha 14 affects expression EXP Orphenadrine affects the expression of GNA14 mRNA CTD PMID:23665939 NCBI chr 1:235,165,775...235,347,986
Ensembl chr 1:235,166,718...235,347,937
JBrowse link
G Gnai1 G protein subunit alpha i1 affects expression EXP Orphenadrine affects the expression of GNAI1 mRNA CTD PMID:23665939 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 affects expression EXP Orphenadrine affects the expression of GPAT3 mRNA CTD PMID:23665939 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpr17 G protein-coupled receptor 17 affects expression EXP Orphenadrine affects the expression of GPR17 mRNA CTD PMID:23665939 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression
multiple interactions
EXP Orphenadrine affects the expression of GPX2 mRNA
[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GPX2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 affects expression EXP Orphenadrine affects the expression of GRIA3 mRNA CTD PMID:23665939 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression EXP Orphenadrine affects the expression of GRIK5 mRNA CTD PMID:23665939 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Gse1 Gse1 coiled-coil protein affects expression EXP Orphenadrine affects the expression of GSE1 mRNA CTD PMID:23665939 NCBI chr19:53,799,945...54,153,732
Ensembl chr19:54,060,622...54,148,970
JBrowse link
G Gstm4 glutathione S-transferase mu 4 affects expression EXP Orphenadrine affects the expression of GSTM4 mRNA CTD PMID:23665939 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
affects expression
EXP [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GSTM3 mRNA
Orphenadrine affects the expression of GSTM3 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression EXP Orphenadrine affects the expression of GSTP1 mRNA CTD PMID:23665939 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Orphenadrine affects the expression of HAL mRNA CTD PMID:23665939 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hebp2 heme binding protein 2 affects expression EXP Orphenadrine affects the expression of HEBP2 mRNA CTD PMID:23665939 NCBI chr 1:13,713,152...13,719,970
Ensembl chr 1:13,714,440...13,719,829
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression EXP Orphenadrine affects the expression of HES1 mRNA CTD PMID:23665939 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hgf hepatocyte growth factor affects expression EXP Orphenadrine affects the expression of HGF mRNA CTD PMID:23665939 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hid1 HID1 domain containing affects expression EXP Orphenadrine affects the expression of HID1 mRNA CTD PMID:23665939 NCBI chr10:103,899,160...103,919,649
Ensembl chr10:103,899,150...103,919,605
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression EXP Orphenadrine affects the expression of HSPA1A mRNA CTD PMID:23665939 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression EXP Orphenadrine affects the expression of HSPA1B mRNA CTD PMID:23665939 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein affects expression EXP Orphenadrine affects the expression of ID1 mRNA CTD PMID:23665939 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein affects expression EXP Orphenadrine affects the expression of ID3 mRNA CTD PMID:23665939 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 affects expression EXP Orphenadrine affects the expression of IDO2 mRNA CTD PMID:23665939 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Ier5 immediate early response 5 affects expression EXP Orphenadrine affects the expression of IER5 mRNA CTD PMID:23665939 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression EXP Orphenadrine affects the expression of IGFBP1 mRNA CTD PMID:23665939 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Ihh Indian hedgehog signaling molecule affects expression EXP Orphenadrine affects the expression of IHH mRNA CTD PMID:23665939 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects expression EXP Orphenadrine affects the expression of IKBKG mRNA CTD PMID:23665939 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il17rb interleukin 17 receptor B affects expression EXP Orphenadrine affects the expression of IL17RB mRNA CTD PMID:23665939 NCBI chr16:6,064,287...6,077,978
Ensembl chr16:6,064,288...6,077,978
JBrowse link
G Il33 interleukin 33 affects expression EXP Orphenadrine affects the expression of IL33 mRNA CTD PMID:23665939 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Inf2 inverted formin 2 affects expression EXP Orphenadrine affects the expression of INF2 mRNA CTD PMID:23665939 NCBI chr 6:137,162,593...137,180,198
Ensembl chr 6:137,164,535...137,177,622
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 affects expression EXP Orphenadrine affects the expression of IP6K2 mRNA CTD PMID:23665939 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Irf7 interferon regulatory factor 7 affects expression EXP Orphenadrine affects the expression of IRF7 mRNA CTD PMID:23665939 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irx1 iroquois homeobox 1 affects expression EXP Orphenadrine affects the expression of IRX1 mRNA CTD PMID:23665939 NCBI chr 1:33,910,912...33,916,741
Ensembl chr 1:33,910,912...33,916,741
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression EXP Orphenadrine affects the expression of ISG15 mRNA CTD PMID:23665939 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgb3 integrin subunit beta 3 affects expression EXP Orphenadrine affects the expression of ITGB3 mRNA CTD PMID:23665939 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression EXP Orphenadrine affects the expression of JUN mRNA CTD PMID:23665939 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression EXP Orphenadrine affects the expression of JUNB mRNA CTD PMID:23665939 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Ka11 type I keratin KA11 affects expression EXP Orphenadrine affects the expression of KA11 mRNA CTD PMID:23665939 NCBI chr10:88,141,667...88,144,624
Ensembl chr10:88,141,667...88,144,625
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 affects expression EXP Orphenadrine affects the expression of KANK2 mRNA CTD PMID:23665939 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 affects expression EXP Orphenadrine affects the expression of KCNJ15 mRNA CTD PMID:23665939 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 affects expression EXP Orphenadrine affects the expression of KCNK5 mRNA CTD PMID:23665939 NCBI chr15:4,554,603...4,597,000
Ensembl chr15:4,554,603...4,597,000
JBrowse link
G Klf10 Kruppel-like factor 10 affects expression EXP Orphenadrine affects the expression of KLF10 mRNA CTD PMID:23665939 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Klhl21 kelch-like family member 21 affects expression EXP Orphenadrine affects the expression of KLHL21 mRNA CTD PMID:23665939 NCBI chr 5:169,181,418...169,190,073
Ensembl chr 5:169,181,418...169,190,073
JBrowse link
G Kmo kynurenine 3-monooxygenase affects expression EXP Orphenadrine affects the expression of KMO mRNA CTD PMID:23665939 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Krt10 keratin 10 affects expression EXP Orphenadrine affects the expression of KRT10 mRNA CTD PMID:23665939 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt8 keratin 8 affects expression EXP Orphenadrine affects the expression of KRT8 mRNA CTD PMID:23665939 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lag3 lymphocyte activating 3 affects expression EXP Orphenadrine affects the expression of LAG3 mRNA CTD PMID:23665939 NCBI chr 4:157,425,644...157,433,700
Ensembl chr 4:157,425,644...157,433,467
JBrowse link
G Lekr1 leucine, glutamate and lysine rich 1 affects expression EXP Orphenadrine affects the expression of LEKR1 mRNA CTD PMID:23665939 NCBI chr 2:157,451,912...157,621,908
Ensembl chr 2:157,453,428...157,620,210
JBrowse link
G Lgals2 galectin 2 affects expression EXP Orphenadrine affects the expression of LGALS2 mRNA CTD PMID:23665939 NCBI chr 7:120,071,122...120,077,612
Ensembl chr 7:120,071,124...120,077,612
JBrowse link
G Lhx8 LIM homeobox 8 affects expression EXP Orphenadrine affects the expression of LHX8 mRNA CTD PMID:23665939 NCBI chr 2:260,572,205...260,598,744
Ensembl chr 2:260,574,190...260,596,777
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 affects expression EXP Orphenadrine affects the expression of LILRB4 mRNA CTD PMID:23665939 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component affects expression EXP Orphenadrine affects the expression of LIN7A mRNA CTD PMID:23665939 NCBI chr 7:49,429,613...49,627,835
Ensembl chr 7:49,385,705...49,656,856
JBrowse link
G Lmod2 leiomodin 2 affects expression EXP Orphenadrine affects the expression of LMOD2 mRNA CTD PMID:23665939 NCBI chr 4:51,553,439...51,561,135
Ensembl chr 4:51,553,454...51,561,174
JBrowse link
G Loxl4 lysyl oxidase-like 4 affects expression EXP Orphenadrine affects the expression of LOXL4 mRNA CTD PMID:23665939 NCBI chr 1:261,833,365...261,853,599
Ensembl chr 1:261,835,992...261,853,495
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 affects expression EXP Orphenadrine affects the expression of LPCAT4 mRNA CTD PMID:23665939 NCBI chr 3:103,725,762...103,733,888
Ensembl chr 3:103,726,238...103,733,354
JBrowse link
G Lpin2 lipin 2 affects expression EXP Orphenadrine affects the expression of LPIN2 mRNA CTD PMID:23665939 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Lpl lipoprotein lipase affects expression EXP Orphenadrine affects the expression of LPL mRNA CTD PMID:23665939 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 affects expression EXP Orphenadrine affects the expression of LRRN4 mRNA CTD PMID:23665939 NCBI chr 3:125,521,879...125,547,685
Ensembl chr 3:125,523,781...125,533,600
JBrowse link
G Ltc4s leukotriene C4 synthase affects expression EXP Orphenadrine affects the expression of LTC4S mRNA CTD PMID:23665939 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Mafb MAF bZIP transcription factor B affects expression EXP Orphenadrine affects the expression of MAFB mRNA CTD PMID:23665939 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Magee1 MAGE family member E1 affects expression EXP Orphenadrine affects the expression of MAGEE1 mRNA CTD PMID:23665939 NCBI chr  X:76,083,553...76,087,100
Ensembl chr  X:76,083,549...76,087,117
JBrowse link
G Map1s microtubule-associated protein 1S affects expression EXP Orphenadrine affects the expression of MAP1S mRNA CTD PMID:23665939 NCBI chr16:20,268,663...20,278,850
Ensembl chr16:20,267,581...20,278,814
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 affects expression EXP Orphenadrine affects the expression of MAP4K2 mRNA CTD PMID:23665939 NCBI chr 1:221,710,622...221,726,274
Ensembl chr 1:221,710,670...221,725,656
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 affects expression EXP Orphenadrine affects the expression of MAP4K4 mRNA CTD PMID:23665939 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 affects expression EXP Orphenadrine affects the expression of MAPK12 mRNA CTD PMID:23665939 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Matn4 matrilin 4 affects expression EXP Orphenadrine affects the expression of MATN4 mRNA CTD PMID:23665939 NCBI chr 3:160,838,632...160,853,650
Ensembl chr 3:160,838,632...160,853,650
JBrowse link
G Mcam melanoma cell adhesion molecule affects expression EXP Orphenadrine affects the expression of MCAM mRNA CTD PMID:23665939 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) affects expression EXP Orphenadrine affects the expression of METAP1D mRNA CTD PMID:23665939 NCBI chr 3:58,084,558...58,160,748
Ensembl chr 3:58,084,606...58,162,675
JBrowse link
G Mex3b mex-3 RNA binding family member B affects expression EXP Orphenadrine affects the expression of MEX3B mRNA CTD PMID:23665939 NCBI chr 1:144,831,523...144,835,758
Ensembl chr 1:144,831,523...144,835,747
JBrowse link
G Mex3d mex-3 RNA binding family member D affects expression EXP Orphenadrine affects the expression of MEX3D mRNA CTD PMID:23665939 NCBI chr 7:12,191,902...12,198,841
Ensembl chr 7:12,192,088...12,198,551
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression EXP Orphenadrine affects the expression of MFGE8 mRNA CTD PMID:23665939 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mid1 midline 1 affects expression EXP Orphenadrine affects the expression of MID1 mRNA CTD PMID:23665939 NCBI chr  X:25,458,782...25,839,941
Ensembl chr  X:25,458,771...25,628,272
JBrowse link
G Mid1ip1 MID1 interacting protein 1 affects expression EXP Orphenadrine affects the expression of MID1IP1 mRNA CTD PMID:23665939 NCBI chr  X:13,114,557...13,119,274
Ensembl chr  X:13,114,569...13,116,743
JBrowse link
G Midn midnolin affects expression EXP Orphenadrine affects the expression of MIDN mRNA CTD PMID:23665939 NCBI chr 7:12,414,303...12,426,712
Ensembl chr 7:12,414,733...12,424,367
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 affects expression EXP Orphenadrine affects the expression of MKNK2 mRNA CTD PMID:23665939 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Mlxip MLX interacting protein affects expression EXP Orphenadrine affects the expression of MLXIP mRNA CTD PMID:23665939 NCBI chr12:38,567,438...38,638,952
Ensembl chr12:38,567,247...38,638,536
JBrowse link
G Mmd monocyte to macrophage differentiation-associated affects expression EXP Orphenadrine affects the expression of MMD mRNA CTD PMID:23665939 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Mmp12 matrix metallopeptidase 12 affects expression EXP Orphenadrine affects the expression of MMP12 mRNA CTD PMID:23665939 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression EXP Orphenadrine affects the expression of MMP15 mRNA CTD PMID:23665939 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mras muscle RAS oncogene homolog affects expression EXP Orphenadrine affects the expression of MRAS mRNA CTD PMID:23665939 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mroh2a maestro heat-like repeat family member 2A affects expression EXP Orphenadrine affects the expression of MROH2A mRNA CTD PMID:23665939 NCBI chr 9:95,308,142...95,346,577
Ensembl chr 9:95,309,759...95,347,384
JBrowse link
G Mst1r macrophage stimulating 1 receptor affects expression EXP Orphenadrine affects the expression of MST1R mRNA CTD PMID:23665939 NCBI chr 8:116,686,601...116,700,132
Ensembl chr 8:116,686,601...116,700,132
JBrowse link
G Mtmr7 myotubularin related protein 7 affects expression EXP Orphenadrine affects the expression of MTMR7 mRNA CTD PMID:23665939 NCBI chr16:54,765,214...54,856,255
Ensembl chr16:54,765,325...54,856,225
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 affects expression EXP Orphenadrine affects the expression of MTSS2 mRNA CTD PMID:23665939 NCBI chr19:40,904,779...40,925,660
Ensembl chr19:40,905,847...40,925,660
JBrowse link
G Mx2 MX dynamin like GTPase 2 affects expression EXP Orphenadrine affects the expression of MX2 mRNA CTD PMID:23665939 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Mybph myosin binding protein H affects expression EXP Orphenadrine affects the expression of MYBPH mRNA CTD PMID:23665939 NCBI chr13:51,034,228...51,041,903
Ensembl chr13:51,034,256...51,041,902
JBrowse link
G Mypop Myb-related transcription factor, partner of profilin affects expression EXP Orphenadrine affects the expression of MYPOP mRNA CTD PMID:23665939 NCBI chr 1:79,898,492...79,909,336
Ensembl chr 1:79,898,551...79,911,513
JBrowse link
G Myrf myelin regulatory factor affects expression EXP Orphenadrine affects the expression of MYRF mRNA CTD PMID:23665939 NCBI chr 1:226,260,558...226,292,650
Ensembl chr 1:226,260,558...226,292,480
JBrowse link
G Nat8f2 N-acetyltransferase 8 (GCN5-related) family member 2 affects expression EXP Orphenadrine affects the expression of NAT8F2 mRNA CTD PMID:23665939 NCBI chr 4:117,749,538...117,752,107
Ensembl chr 4:117,750,649...117,751,329
Ensembl chr 4:117,750,649...117,751,329
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects expression EXP Orphenadrine affects the expression of NCAPH mRNA CTD PMID:23665939 NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 affects expression EXP Orphenadrine affects the expression of NCOA7 mRNA CTD PMID:23665939 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Orphenadrine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 affects expression EXP Orphenadrine affects the expression of NEURL3 mRNA CTD PMID:23665939 NCBI chr 9:42,831,737...42,841,765
Ensembl chr 9:42,831,742...42,839,837
JBrowse link
G Nfkbiz NFKB inhibitor zeta affects expression EXP Orphenadrine affects the expression of NFKBIZ mRNA CTD PMID:23665939 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Ninj2 ninjurin 2 affects expression EXP Orphenadrine affects the expression of NINJ2 mRNA CTD PMID:23665939 NCBI chr 4:152,630,464...152,733,631
Ensembl chr 4:152,630,469...152,733,633
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Orphenadrine affects the expression of NIPAL2 mRNA CTD PMID:23665939 NCBI chr 7:73,339,706...73,450,262
Ensembl chr 7:73,339,706...73,450,262
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 affects expression EXP Orphenadrine affects the expression of NLRC4 mRNA CTD PMID:23665939 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250
JBrowse link
G Noct nocturnin affects expression EXP Orphenadrine affects the expression of NOCT mRNA CTD PMID:23665939 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein affects expression EXP Orphenadrine affects the expression of NOS1AP mRNA CTD PMID:23665939 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Orphenadrine affects the expression of NOS3 mRNA CTD PMID:23665939 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Npy neuropeptide Y affects expression EXP Orphenadrine affects the expression of NPY mRNA CTD PMID:23665939 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects expression EXP Orphenadrine affects the expression of NR1D1 mRNA CTD PMID:23665939 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nrep neuronal regeneration related protein affects expression EXP Orphenadrine affects the expression of NREP mRNA CTD PMID:23665939 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nrg1 neuregulin 1 affects expression EXP Orphenadrine affects the expression of NRG1 mRNA CTD PMID:23665939 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrxn1 neurexin 1 affects expression EXP Orphenadrine affects the expression of NRXN1 mRNA CTD PMID:23665939 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator affects expression EXP Orphenadrine affects the expression of NUPR1 mRNA CTD PMID:23665939 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oat ornithine aminotransferase affects expression EXP Orphenadrine affects the expression of OAT mRNA CTD PMID:23665939 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Ogn osteoglycin affects expression EXP Orphenadrine affects the expression of OGN mRNA CTD PMID:23665939 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Olr1198 olfactory receptor 1198 affects expression EXP Orphenadrine affects the expression of OLR1198 mRNA CTD PMID:23665939
G Olr1395 olfactory receptor 1395 affects expression EXP Orphenadrine affects the expression of OLR1395 mRNA CTD PMID:23665939 NCBI chr10:34,692,870...34,693,799
Ensembl chr10:34,692,870...34,693,799
JBrowse link
G Olr1428 olfactory receptor 1428 affects expression EXP Orphenadrine affects the expression of OLR1428 mRNA CTD PMID:23665939
G Olr1451 olfactory receptor 1451 affects expression EXP Orphenadrine affects the expression of OLR1451 mRNA CTD PMID:23665939 NCBI chr10:44,706,744...44,707,463 JBrowse link
G Olr1679 olfactory receptor 1679 affects expression EXP Orphenadrine affects the expression of OLR1679 mRNA CTD PMID:23665939 NCBI chr20:34,404...35,342
Ensembl chr20:34,404...35,342
JBrowse link
G Omd osteomodulin affects expression EXP Orphenadrine affects the expression of OMD mRNA CTD PMID:23665939 NCBI chr17:15,476,100...15,484,324
Ensembl chr17:15,475,710...15,484,269
Ensembl chr17:15,475,710...15,484,269
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression EXP Orphenadrine affects the expression of OSGIN1 mRNA CTD PMID:23665939 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 affects expression EXP Orphenadrine affects the expression of P3H2 mRNA CTD PMID:23665939 NCBI chr11:78,028,885...78,169,746
Ensembl chr11:78,029,038...78,169,648
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 affects expression EXP Orphenadrine affects the expression of P3H4 mRNA CTD PMID:23665939 NCBI chr10:88,318,231...88,325,326
Ensembl chr10:88,318,817...88,325,326
JBrowse link
G Panx2 pannexin 2 affects expression EXP Orphenadrine affects the expression of PANX2 mRNA CTD PMID:23665939 NCBI chr 7:130,042,948...130,053,034
Ensembl chr 7:130,042,947...130,053,032
JBrowse link
G Pcdh12 protocadherin 12 affects expression EXP Orphenadrine affects the expression of PCDH12 mRNA CTD PMID:23665939 NCBI chr18:31,415,533...31,431,108
Ensembl chr18:31,414,250...31,430,973
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 affects expression EXP Orphenadrine affects the expression of PCP4L1 mRNA CTD PMID:23665939 NCBI chr13:89,542,377...89,565,920
Ensembl chr13:89,542,378...89,565,813
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 affects expression EXP Orphenadrine affects the expression of PCSK9 mRNA CTD PMID:23665939 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pde5a phosphodiesterase 5A affects expression EXP Orphenadrine affects the expression of PDE5A mRNA CTD PMID:23665939 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression EXP Orphenadrine affects the expression of PDK4 mRNA CTD PMID:23665939 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdpn podoplanin affects expression EXP Orphenadrine affects the expression of PDPN mRNA CTD PMID:23665939 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Per2 period circadian regulator 2 affects expression EXP Orphenadrine affects the expression of PER2 mRNA CTD PMID:23665939 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Pfkm phosphofructokinase, muscle affects expression EXP Orphenadrine affects the expression of PFKM mRNA CTD PMID:23665939 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 affects expression EXP Orphenadrine affects the expression of PHLDA2 mRNA CTD PMID:23665939 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 affects expression EXP Orphenadrine affects the expression of PHLDA3 mRNA CTD PMID:23665939 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Phldb3 pleckstrin homology-like domain, family B, member 3 affects expression EXP Orphenadrine affects the expression of PHLDB3 mRNA CTD PMID:23665939 NCBI chr 1:81,474,553...81,492,631
Ensembl chr 1:81,474,553...81,492,631
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 affects expression EXP Orphenadrine affects the expression of PHOSPHO1 mRNA CTD PMID:23665939 NCBI chr10:83,635,557...83,643,862
Ensembl chr10:83,636,518...83,643,859
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma affects expression EXP Orphenadrine affects the expression of PIP5K1C mRNA CTD PMID:23665939 NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 affects expression EXP Orphenadrine affects the expression of PLEKHF2 mRNA CTD PMID:23665939 NCBI chr 5:24,240,241...24,255,922
Ensembl chr 5:24,240,242...24,255,606
JBrowse link
G Plekhh1 pleckstrin homology, MyTH4 and FERM domain containing H1 affects expression EXP Orphenadrine affects the expression of PLEKHH1 mRNA CTD PMID:23665939 NCBI chr 6:102,215,424...102,264,345
Ensembl chr 6:102,215,603...102,262,417
JBrowse link
G Plin3 perilipin 3 affects expression EXP Orphenadrine affects the expression of PLIN3 mRNA CTD PMID:23665939 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 affects expression EXP Orphenadrine affects the expression of PMEPA1 mRNA CTD PMID:23665939 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Pmp22 peripheral myelin protein 22 affects expression EXP Orphenadrine affects the expression of PMP22 mRNA CTD PMID:23665939 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects expression EXP Orphenadrine affects the expression of POLG2 mRNA CTD PMID:23665939 NCBI chr10:94,968,836...94,979,259
Ensembl chr10:94,968,836...94,979,259
JBrowse link
G Ppm1j protein phosphatase, Mg2+/Mn2+ dependent, 1J affects expression EXP Orphenadrine affects the expression of PPM1J mRNA CTD PMID:23665939 NCBI chr 2:207,263,307...207,268,601
Ensembl chr 2:207,262,934...207,268,609
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K affects expression EXP Orphenadrine affects the expression of PPM1K mRNA CTD PMID:23665939 NCBI chr 4:88,694,395...88,721,374
Ensembl chr 4:88,694,583...88,718,533
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A affects expression EXP Orphenadrine affects the expression of PPP1R1A mRNA CTD PMID:23665939 NCBI chr 7:145,146,480...145,154,131
Ensembl chr 7:145,146,481...145,154,131
JBrowse link
G Prelid2 PRELI domain containing 2 affects expression EXP Orphenadrine affects the expression of PRELID2 mRNA CTD PMID:23665939 NCBI chr18:36,198,522...36,286,217
Ensembl chr18:36,194,778...36,285,444
JBrowse link
G Prkch protein kinase C, eta affects expression EXP Orphenadrine affects the expression of PRKCH mRNA CTD PMID:23665939 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Prlr prolactin receptor affects expression EXP Orphenadrine affects the expression of PRLR mRNA CTD PMID:23665939 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Prrg4 proline rich and Gla domain 4 affects expression EXP Orphenadrine affects the expression of PRRG4 mRNA CTD PMID:23665939 NCBI chr 3:94,783,866...94,808,861
Ensembl chr 3:94,784,008...94,808,861
JBrowse link
G Prss53 serine protease 53 affects expression EXP Orphenadrine affects the expression of PRSS53 mRNA CTD PMID:23665939 NCBI chr 1:199,331,108...199,337,129
Ensembl chr 1:199,331,787...199,336,451
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N affects expression EXP Orphenadrine affects the expression of PTPRN mRNA CTD PMID:23665939 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Pvr PVR cell adhesion molecule affects expression EXP Orphenadrine affects the expression of PVR mRNA CTD PMID:23665939 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701
JBrowse link
G Pwwp2b PWWP domain containing 2B affects expression EXP Orphenadrine affects the expression of PWWP2B mRNA CTD PMID:23665939 NCBI chr 1:211,579,706...211,600,715
Ensembl chr 1:211,582,077...211,600,689
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 affects expression EXP Orphenadrine affects the expression of RAB11FIP5 mRNA CTD PMID:23665939 NCBI chr 4:117,113,067...117,154,495
Ensembl chr 4:117,115,076...117,153,907
JBrowse link
G Rab23 RAB23, member RAS oncogene family affects expression EXP Orphenadrine affects the expression of RAB23 mRNA CTD PMID:23665939 NCBI chr 9:38,469,784...38,496,185
Ensembl chr 9:38,470,298...38,495,176
JBrowse link
G Rab3d RAB3D, member RAS oncogene family affects expression EXP Orphenadrine affects the expression of RAB3D mRNA CTD PMID:23665939 NCBI chr 8:22,920,238...22,929,368
Ensembl chr 8:22,918,699...22,929,294
JBrowse link
G Rarg retinoic acid receptor, gamma affects expression EXP Orphenadrine affects the expression of RARG mRNA CTD PMID:23665939 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rassf1 Ras association domain family member 1 affects expression EXP Orphenadrine affects the expression of RASSF1 mRNA CTD PMID:23665939 NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289
JBrowse link
G Rell1 RELT-like 1 affects expression EXP Orphenadrine affects the expression of RELL1 mRNA CTD PMID:23665939 NCBI chr14:45,982,244...46,041,907
Ensembl chr14:45,982,244...46,041,866
JBrowse link
G Renbp renin binding protein affects expression EXP Orphenadrine affects the expression of RENBP mRNA CTD PMID:23665939 NCBI chr  X:156,854,490...156,863,548
Ensembl chr  X:156,854,594...156,863,528
JBrowse link
G Repin1 replication initiator 1 affects expression EXP Orphenadrine affects the expression of REPIN1 mRNA CTD PMID:23665939 NCBI chr 4:78,232,454...78,237,498
Ensembl chr 4:78,233,332...78,236,781
JBrowse link
G Resp18 regulated endocrine-specific protein 18 affects expression EXP Orphenadrine affects the expression of RESP18 mRNA CTD PMID:23665939 NCBI chr 9:82,470,794...82,477,136
Ensembl chr 9:82,470,759...82,477,181
JBrowse link
G RGD1305464 similar to human chromosome 15 open reading frame 39 affects expression EXP Orphenadrine affects the expression of RGD1305464 mRNA CTD PMID:23665939 NCBI chr 8:61,913,588...61,923,149
Ensembl chr 8:61,913,589...61,919,874
JBrowse link
G RGD1311946 similar to RIKEN cDNA 1810055G02 affects expression EXP Orphenadrine affects the expression of RGD1311946 mRNA CTD PMID:23665939 NCBI chr 1:218,945,565...218,954,274
Ensembl chr 1:218,945,508...218,954,280
JBrowse link
G RGD1559950 similar to STELLA affects expression EXP Orphenadrine affects the expression of RGD1559950 mRNA CTD PMID:23665939 NCBI chr17:2,920,483...2,921,683 JBrowse link
G RGD1561149 similar to mKIAA1522 protein affects expression EXP Orphenadrine affects the expression of RGD1561149 mRNA CTD PMID:23665939 NCBI chr 5:147,403,948...147,427,587
Ensembl chr 5:147,403,948...147,412,705
JBrowse link
G RGD1564515 similar to alpha 1B-glycoprotein affects expression EXP Orphenadrine affects the expression of RGD1564515 mRNA CTD PMID:23665939 NCBI chr 7:101,068,590...101,072,944 JBrowse link
G RGD1564937 similar to RIKEN cDNA 1110032A03 affects expression EXP Orphenadrine affects the expression of RGD1564937 mRNA CTD PMID:23665939 NCBI chr 8:55,169,413...55,194,692
Ensembl chr 8:55,191,085...55,194,692
JBrowse link
G Rgs16 regulator of G-protein signaling 16 affects expression EXP Orphenadrine affects the expression of RGS16 mRNA CTD PMID:23665939 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 affects expression EXP Orphenadrine affects the expression of RHBDF2 mRNA CTD PMID:23665939 NCBI chr10:105,573,759...105,600,885
Ensembl chr10:105,573,752...105,600,913
JBrowse link
G Rhoc ras homolog family member C affects expression EXP Orphenadrine affects the expression of RHOC mRNA CTD PMID:23665939 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rhof ras homolog family member F, filopodia associated affects expression EXP Orphenadrine affects the expression of RHOF mRNA CTD PMID:23665939 NCBI chr12:38,879,763...38,894,095
Ensembl chr12:38,880,377...38,894,582
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 affects expression EXP Orphenadrine affects the expression of RMDN2 mRNA CTD PMID:23665939 NCBI chr 6:2,215,062...2,292,288
Ensembl chr 6:2,216,623...2,280,777
JBrowse link
G Rnd1 Rho family GTPase 1 affects expression EXP Orphenadrine affects the expression of RND1 mRNA CTD PMID:23665939 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Orphenadrine affects the expression of SBSPON mRNA CTD PMID:23665939 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Scd stearoyl-CoA desaturase affects expression EXP Orphenadrine affects the expression of SCD1 mRNA CTD PMID:23665939 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha affects expression EXP Orphenadrine affects the expression of SCNN1A mRNA CTD PMID:23665939 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Sdc3 syndecan 3 affects expression EXP Orphenadrine affects the expression of SDC3 mRNA CTD PMID:23665939 NCBI chr 5:148,923,098...148,956,404
Ensembl chr 5:148,923,098...148,956,404
JBrowse link
G Sebox SEBOX homeobox affects expression EXP Orphenadrine affects the expression of SEBOX mRNA CTD PMID:23665939 NCBI chr10:65,771,370...65,774,748
Ensembl chr10:65,772,443...65,773,314
JBrowse link
G Serinc2 serine incorporator 2 affects expression EXP Orphenadrine affects the expression of SERINC2 mRNA CTD PMID:23665939 NCBI chr 5:148,470,060...148,492,232
Ensembl chr 5:148,470,061...148,492,232
JBrowse link
G Serpina7 serpin family A member 7 affects expression EXP Orphenadrine affects the expression of SERPINA7 mRNA CTD PMID:23665939 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Sertad1 SERTA domain containing 1 affects expression EXP Orphenadrine affects the expression of SERTAD1 mRNA CTD PMID:23665939 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase affects expression EXP Orphenadrine affects the expression of SETD7 mRNA CTD PMID:23665939 NCBI chr 2:140,576,188...140,618,405
Ensembl chr 2:140,576,188...140,618,405
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 affects expression EXP Orphenadrine affects the expression of SGK1 mRNA CTD PMID:23665939 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B affects expression EXP Orphenadrine affects the expression of SH3PXD2B mRNA CTD PMID:23665939 NCBI chr10:17,209,152...17,296,449
Ensembl chr10:17,209,212...17,291,876
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression EXP Orphenadrine affects the expression of SHANK3 mRNA CTD PMID:23665939 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Shisa4 shisa family member 4 affects expression EXP Orphenadrine affects the expression of SHISA4 mRNA CTD PMID:23665939 NCBI chr13:52,193,989...52,197,205
Ensembl chr13:52,193,989...52,197,205
JBrowse link
G Shroom3 shroom family member 3 affects expression EXP Orphenadrine affects the expression of SHROOM3 mRNA CTD PMID:23665939 NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242
JBrowse link
G Sidt1 SID1 transmembrane family, member 1 affects expression EXP Orphenadrine affects the expression of SIDT1 mRNA CTD PMID:23665939 NCBI chr11:61,320,480...61,416,560
Ensembl chr11:61,321,459...61,417,842
JBrowse link
G Sinhcaf SIN3-HDAC complex associated factor affects expression EXP Orphenadrine affects the expression of SINHCAF mRNA CTD PMID:23665939 NCBI chr 4:183,401,314...183,426,439
Ensembl chr 4:183,401,318...183,426,439
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 affects expression EXP Orphenadrine affects the expression of SIPA1 mRNA CTD PMID:23665939 NCBI chr 1:221,006,305...221,018,820
Ensembl chr 1:221,006,340...221,015,929
JBrowse link
G Skil SKI-like proto-oncogene affects expression EXP Orphenadrine affects the expression of SKIL mRNA CTD PMID:23665939 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Slc12a4 solute carrier family 12 member 4 affects expression EXP Orphenadrine affects the expression of SLC12A4 mRNA CTD PMID:23665939 NCBI chr19:37,917,003...37,938,952
Ensembl chr19:37,917,014...37,938,857
JBrowse link
G Slc16a10 solute carrier family 16 member 10 affects expression EXP Orphenadrine affects the expression of SLC16A10 mRNA CTD PMID:23665939 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc16a11 solute carrier family 16, member 11 affects expression EXP Orphenadrine affects the expression of SLC16A11 mRNA CTD PMID:23665939 NCBI chr10:56,822,697...56,826,480
Ensembl chr10:56,822,756...56,826,479
JBrowse link
G Slc16a14 solute carrier family 16, member 14 affects expression EXP Orphenadrine affects the expression of SLC16A14 mRNA CTD PMID:23665939 NCBI chr 9:92,503,602...92,531,163
Ensembl chr 9:92,503,597...92,530,938
JBrowse link
G Slc16a5 solute carrier family 16 member 5 affects expression EXP Orphenadrine affects the expression of SLC16A5 mRNA CTD PMID:23665939 NCBI chr10:104,019,888...104,035,735
Ensembl chr10:104,019,888...104,034,595
JBrowse link
G Slc16a6 solute carrier family 16, member 6 affects expression EXP Orphenadrine affects the expression of SLC16A6 mRNA CTD PMID:23665939 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc1a4 solute carrier family 1 member 4 affects expression EXP Orphenadrine affects the expression of SLC1A4 mRNA CTD PMID:23665939 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Orphenadrine inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Orphenadrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc30a2 solute carrier family 30 member 2 affects expression EXP Orphenadrine affects the expression of SLC30A2 mRNA CTD PMID:23665939 NCBI chr 5:152,559,577...152,571,800
Ensembl chr 5:152,559,577...152,571,799
JBrowse link
G Slc35f2 solute carrier family 35, member F2 affects expression EXP Orphenadrine affects the expression of SLC35F2 mRNA CTD PMID:23665939 NCBI chr 8:58,347,474...58,391,462
Ensembl chr 8:58,347,736...58,391,599
JBrowse link
G Slc41a1 solute carrier family 41 member 1 affects expression EXP Orphenadrine affects the expression of SLC41A1 mRNA CTD PMID:23665939 NCBI chr13:48,607,308...48,627,999
Ensembl chr13:48,607,308...48,627,999
JBrowse link
G Slc6a8 solute carrier family 6 member 8 affects expression EXP Orphenadrine affects the expression of SLC6A8 mRNA CTD PMID:23665939 NCBI chr  X:157,129,987...157,139,321
Ensembl chr  X:157,129,987...157,139,291
JBrowse link
G Slc7a4 solute carrier family 7, member 4 affects expression EXP Orphenadrine affects the expression of SLC7A4 mRNA CTD PMID:23665939 NCBI chr11:87,445,585...87,450,008
Ensembl chr11:87,446,382...87,449,940
JBrowse link
G Slc9a7 solute carrier family 9 member A7 affects expression EXP Orphenadrine affects the expression of SLC9A7 mRNA CTD PMID:23665939 NCBI chr  X:2,434,918...2,615,936
Ensembl chr  X:2,435,305...2,614,770
JBrowse link
G Smad6 SMAD family member 6 affects expression EXP Orphenadrine affects the expression of SMAD6 mRNA CTD PMID:23665939 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smtnl2 smoothelin-like 2 affects expression EXP Orphenadrine affects the expression of SMTNL2 mRNA CTD PMID:23665939 NCBI chr10:58,951,845...58,973,020
Ensembl chr10:58,951,842...58,973,020
JBrowse link
G Snx10 sorting nexin 10 affects expression EXP Orphenadrine affects the expression of SNX10 mRNA CTD PMID:23665939 NCBI chr 4:81,311,490...81,375,248
Ensembl chr 4:81,311,490...81,374,158
JBrowse link
G Sort1 sortilin 1 affects expression EXP Orphenadrine affects the expression of SORT1 mRNA CTD PMID:23665939 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sox18 SRY-box transcription factor 18 affects expression EXP Orphenadrine affects the expression of SOX18 mRNA CTD PMID:23665939 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
G Sox4 SRY-box transcription factor 4 affects expression EXP Orphenadrine affects the expression of SOX4 mRNA CTD PMID:23665939 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex affects expression EXP Orphenadrine affects the expression of SPC25 mRNA CTD PMID:23665939 NCBI chr 3:55,438,534...55,451,961
Ensembl chr 3:55,438,536...55,451,798
JBrowse link
G Spetex-2C Spetex-2C protein affects expression EXP Orphenadrine affects the expression of SPETEX-2C mRNA CTD PMID:23665939 NCBI chr15:5,506,209...5,642,116 JBrowse link
G Spetex-2F Spetex-2F protein affects expression EXP Orphenadrine affects the expression of SPETEX-2F mRNA CTD PMID:23665939 NCBI chr15:5,463,852...5,509,839
Ensembl chr15:5,414,416...5,510,289
JBrowse link
G Spetex-2G Spetex-2G protein affects expression EXP Orphenadrine affects the expression of SPETEX-2G mRNA CTD PMID:23665939 NCBI chr15:5,818,829...5,822,903 JBrowse link
G Spink9 serine peptidase inhibitor, Kazal type 9 affects expression EXP Orphenadrine affects the expression of SPINK9 mRNA CTD PMID:23665939 NCBI chr 2:36,088,827...36,096,583
Ensembl chr  X:43,012,612...43,015,896
Ensembl chr 2:43,012,612...43,015,896
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 affects expression EXP Orphenadrine affects the expression of SPOCK2 mRNA CTD PMID:23665939 NCBI chr20:29,654,926...29,679,927
Ensembl chr20:29,655,226...29,677,926
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 affects expression EXP Orphenadrine affects the expression of SRCIN1 mRNA CTD PMID:23665939 NCBI chr10:85,460,059...85,517,671
Ensembl chr10:85,460,059...85,517,683
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects expression EXP Orphenadrine affects the expression of SRD5A1 mRNA CTD PMID:23665939 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression EXP Orphenadrine affects the expression of STAC3 mRNA CTD PMID:23665939 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stard9 StAR-related lipid transfer domain containing 9 affects expression EXP Orphenadrine affects the expression of STARD9 mRNA CTD PMID:23665939 NCBI chr 3:112,428,361...112,659,558
Ensembl chr 3:112,428,395...112,659,140
JBrowse link
G Stxbp1 syntaxin binding protein 1 affects expression EXP Orphenadrine affects the expression of STXBP1 mRNA CTD PMID:23665939 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 affects expression EXP Orphenadrine affects the expression of SULT1E1 mRNA CTD PMID:23665939 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 affects expression EXP Orphenadrine affects the expression of SYDE1 mRNA CTD PMID:23665939 NCBI chr 7:14,037,646...14,043,632
Ensembl chr 7:14,037,620...14,043,779
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 affects expression EXP Orphenadrine affects the expression of SYNGAP1 mRNA CTD PMID:23665939 NCBI chr20:5,535,434...5,564,657
Ensembl chr20:5,535,432...5,564,437
JBrowse link
G Synj2 synaptojanin 2 affects expression EXP Orphenadrine affects the expression of SYNJ2 mRNA CTD PMID:23665939 NCBI chr 1:46,835,922...46,932,544
Ensembl chr 1:46,835,971...46,932,529
JBrowse link
G Synm synemin affects expression EXP Orphenadrine affects the expression of SYNM mRNA CTD PMID:23665939 NCBI chr 1:128,692,112...128,722,048
Ensembl chr 1:128,692,112...128,722,048
JBrowse link
G Tbcel tubulin folding cofactor E-like affects expression EXP Orphenadrine affects the expression of TBCEL mRNA CTD PMID:23665939 NCBI chr 8:46,691,488...46,750,816
Ensembl chr 8:46,694,561...46,750,898
JBrowse link
G Tead2 TEA domain transcription factor 2 affects expression EXP Orphenadrine affects the expression of TEAD2 mRNA CTD PMID:23665939 NCBI chr 1:101,213,782...101,230,483
Ensembl chr 1:101,213,788...101,230,477
JBrowse link
G Tenm2 teneurin transmembrane protein 2 affects expression EXP Orphenadrine affects the expression of TENM2 mRNA CTD PMID:23665939 NCBI chr10:20,846,091...21,791,771
Ensembl chr10:20,844,899...21,265,026
JBrowse link
G Tex13b testis expressed 13B affects expression EXP Orphenadrine affects the expression of TEX13B mRNA CTD PMID:23665939 NCBI chr  X:112,156,631...112,160,456
Ensembl chr  X:112,154,759...112,159,458
JBrowse link
G Tex36 testis expressed 36 affects expression EXP Orphenadrine affects the expression of TEX36 mRNA CTD PMID:23665939 NCBI chr 1:205,615,759...205,630,073
Ensembl chr 1:205,615,761...205,669,760
JBrowse link
G Them6 thioesterase superfamily member 6 affects expression EXP Orphenadrine affects the expression of THEM6 mRNA CTD PMID:23665939 NCBI chr 7:115,956,276...115,959,453
Ensembl chr 7:115,956,276...115,959,453
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain affects expression EXP Orphenadrine affects the expression of TIFA mRNA CTD PMID:23665939 NCBI chr 2:232,104,394...232,137,425
Ensembl chr 2:232,104,809...232,137,422
JBrowse link
G Tlcd4 TLC domain containing 4 affects expression EXP Orphenadrine affects the expression of TLCD4 mRNA CTD PMID:23665939 NCBI chr 2:224,768,034...224,843,198
Ensembl chr 2:224,772,893...224,802,997
JBrowse link
G Tlnrd1 talin rod domain containing 1 affects expression EXP Orphenadrine affects the expression of TLNRD1 mRNA CTD PMID:23665939 NCBI chr 1:146,027,821...146,029,840
Ensembl chr 1:146,027,822...146,029,840
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Orphenadrine affects the expression of TMBIM1 mRNA CTD PMID:23665939 NCBI chr 9:81,569,289...81,586,469
Ensembl chr 9:81,569,289...81,586,553
JBrowse link
G Tmem184b transmembrane protein 184B affects expression EXP Orphenadrine affects the expression of TMEM184B mRNA CTD PMID:23665939 NCBI chr 7:120,593,336...120,636,592
Ensembl chr 7:120,593,336...120,636,592
JBrowse link
G Tmem184c transmembrane protein 184C affects expression EXP Orphenadrine affects the expression of TMEM184C mRNA CTD PMID:23665939 NCBI chr19:34,041,128...34,057,165
Ensembl chr19:34,041,219...34,057,159
JBrowse link
G Tmem200b transmembrane protein 200B affects expression EXP Orphenadrine affects the expression of TMEM200B mRNA CTD PMID:23665939 NCBI chr 5:150,079,504...150,082,268
Ensembl chr 5:150,080,072...150,080,926
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 affects expression EXP Orphenadrine affects the expression of TNFAIP2 mRNA CTD PMID:23665939 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B affects expression EXP Orphenadrine affects the expression of TNFRSF11B mRNA CTD PMID:23665939 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A affects expression EXP Orphenadrine affects the expression of TNFRSF12A mRNA CTD PMID:23665939 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 affects expression EXP Orphenadrine affects the expression of TNK1 mRNA CTD PMID:23665939 NCBI chr10:56,458,650...56,475,183
Ensembl chr10:56,459,108...56,465,393
JBrowse link
G Tns1 tensin 1 affects expression EXP Orphenadrine affects the expression of TNS1 mRNA CTD PMID:23665939 NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987
JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 affects expression EXP Orphenadrine affects the expression of TOGARAM2 mRNA CTD PMID:23665939 NCBI chr 6:23,358,762...23,416,386
Ensembl chr 6:23,359,009...23,404,368
JBrowse link
G Tox3 TOX high mobility group box family member 3 affects expression EXP Orphenadrine affects the expression of TOX3 mRNA CTD PMID:23665939 NCBI chr19:18,079,022...18,188,366
Ensembl chr19:18,079,094...18,188,330
JBrowse link
G Tpm1 tropomyosin 1 affects expression EXP Orphenadrine affects the expression of TPM1 mRNA CTD PMID:23665939 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Traf4 Tnf receptor associated factor 4 affects expression EXP Orphenadrine affects the expression of TRAF4 mRNA CTD PMID:23665939 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
JBrowse link
G Trim36 tripartite motif-containing 36 affects expression EXP Orphenadrine affects the expression of TRIM36 mRNA CTD PMID:23665939 NCBI chr18:40,081,028...40,134,673
Ensembl chr18:40,082,442...40,134,504
JBrowse link
G Trim54 tripartite motif-containing 54 affects expression EXP Orphenadrine affects the expression of TRIM54 mRNA CTD PMID:23665939 NCBI chr 6:26,603,364...26,623,950
Ensembl chr 6:26,603,369...26,624,092
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 affects expression EXP Orphenadrine affects the expression of TRPM2 mRNA CTD PMID:23665939 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 affects expression EXP Orphenadrine affects the expression of TRPV2 mRNA CTD PMID:23665939 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression EXP Orphenadrine affects the expression of TSC22D3 mRNA CTD PMID:23665939 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Ttpal alpha tocopherol transfer protein like affects expression EXP Orphenadrine affects the expression of TTPAL mRNA CTD PMID:23665939 NCBI chr 3:159,995,013...160,015,314
Ensembl chr 3:159,995,064...160,013,274
JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 affects expression EXP Orphenadrine affects the expression of UBA7 mRNA CTD PMID:23665939 NCBI chr 8:116,754,178...116,766,765
Ensembl chr 8:116,754,178...116,764,126
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 affects expression EXP Orphenadrine affects the expression of UGT2A3 mRNA CTD PMID:23665939 NCBI chr14:22,251,507...22,267,899
Ensembl chr14:22,192,970...22,619,968
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 affects expression EXP Orphenadrine affects the expression of UGT2B1 mRNA CTD PMID:23665939 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Unc5b unc-5 netrin receptor B affects expression EXP Orphenadrine affects the expression of UNC5B mRNA CTD PMID:23665939 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Unkl unk like zinc finger affects expression EXP Orphenadrine affects the expression of UNKL mRNA CTD PMID:23665939 NCBI chr10:14,547,126...14,593,090
Ensembl chr10:14,547,172...14,590,762
JBrowse link
G Upp2 uridine phosphorylase 2 affects expression EXP Orphenadrine affects the expression of UPP2 mRNA CTD PMID:23665939 NCBI chr 3:44,806,106...44,846,464
Ensembl chr 3:44,806,106...44,846,464
JBrowse link
G Usp18 ubiquitin specific peptidase 18 affects expression EXP Orphenadrine affects the expression of USP18 mRNA CTD PMID:23665939 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G UST4r integral membrane transport protein UST4r affects expression EXP Orphenadrine affects the expression of UST4R mRNA CTD PMID:23665939 NCBI chr 1:224,319,927...224,389,499
Ensembl chr 1:224,319,077...224,389,499
JBrowse link
G Vav2 vav guanine nucleotide exchange factor 2 affects expression EXP Orphenadrine affects the expression of VAV2 mRNA CTD PMID:23665939 NCBI chr 3:5,811,504...5,976,311
Ensembl chr 3:5,811,504...5,976,244
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 affects expression EXP Orphenadrine affects the expression of VIPR1 mRNA CTD PMID:23665939 NCBI chr 8:130,283,453...130,313,431 JBrowse link
G Vnn1 vanin 1 affects expression EXP Orphenadrine affects the expression of VNN1 mRNA CTD PMID:23665939 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Vom2r3 vomeronasal 2 receptor, 3 affects expression EXP Orphenadrine affects the expression of VOM2R3 mRNA CTD PMID:23665939 NCBI chr 1:69,007,591...69,016,444 JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 affects expression EXP Orphenadrine affects the expression of WFDC1 mRNA CTD PMID:23665939 NCBI chr19:52,313,771...52,332,721
Ensembl chr19:52,313,795...52,332,697
JBrowse link
G Wipf3 WAS/WASL interacting protein family, member 3 affects expression EXP Orphenadrine affects the expression of WIPF3 mRNA CTD PMID:23665939 NCBI chr 4:84,596,305...84,676,775
Ensembl chr 4:84,597,323...84,676,775
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 affects expression EXP Orphenadrine affects the expression of XPNPEP2 mRNA CTD PMID:23665939 NCBI chr  X:134,940,656...134,969,874
Ensembl chr  X:134,940,615...134,969,996
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 affects expression EXP Orphenadrine affects the expression of ZBTB10 mRNA CTD PMID:23665939 NCBI chr 2:94,692,939...94,730,976
Ensembl chr 2:94,692,939...94,730,978
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 affects expression EXP Orphenadrine affects the expression of ZBTB42 mRNA CTD PMID:23665939 NCBI chr 6:137,238,899...137,247,115
Ensembl chr 6:137,243,185...137,245,313
JBrowse link
G Zc2hc1a zinc finger, C2HC-type containing 1A affects expression EXP Orphenadrine affects the expression of ZC2HC1A mRNA CTD PMID:23665939 NCBI chr 2:96,482,938...96,520,202
Ensembl chr 2:96,482,944...96,520,137
JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 affects expression EXP Orphenadrine affects the expression of ZDHHC8 mRNA CTD PMID:23665939 NCBI chr11:86,903,122...86,917,261
Ensembl chr11:86,903,122...86,915,715
JBrowse link
G Zfp319 zinc finger protein 319 affects expression EXP Orphenadrine affects the expression of ZFP319 mRNA CTD PMID:23665939 NCBI chr19:10,119,253...10,123,232
Ensembl chr19:10,119,253...10,123,232
JBrowse link
G Zfp334 zinc finger protein 334 affects expression EXP Orphenadrine affects the expression of ZFP334 mRNA CTD PMID:23665939 NCBI chr 3:162,054,995...162,067,545 JBrowse link
G Zfp354a zinc finger protein 354A affects expression EXP Orphenadrine affects the expression of ZFP354A mRNA CTD PMID:23665939 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
G Zfp36 zinc finger protein 36 affects expression EXP Orphenadrine affects the expression of ZFP36 mRNA CTD PMID:23665939 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 affects expression EXP Orphenadrine affects the expression of ZFP36L2 mRNA CTD PMID:23665939 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link
G Zfp503 zinc finger protein 503 affects expression EXP Orphenadrine affects the expression of ZFP503 mRNA CTD PMID:23665939 NCBI chr15:2,374,582...2,378,370
Ensembl chr15:2,374,582...2,378,370
JBrowse link
G Zfp668 zinc finger protein 668 affects expression EXP Orphenadrine affects the expression of ZFP668 mRNA CTD PMID:23665939 NCBI chr 1:199,310,935...199,321,231
Ensembl chr 1:199,310,935...199,320,727
JBrowse link
pergolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]
Pergolide inhibits the reaction [Levodopa results in increased expression of BAX protein]
CTD PMID:15081873 PMID:15672541 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein] CTD PMID:15081873 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Drd1 dopamine receptor D1 increases activity ISO Pergolide results in increased activity of DRD1 protein CTD PMID:16129789 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 increases activity ISO Pergolide results in increased activity of DRD2 protein CTD PMID:16129789 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression
increases secretion
ISO Pergolide results in increased expression of GDNF mRNA
Pergolide results in increased secretion of GDNF protein
CTD PMID:12770616 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO Pergolide results in decreased activity of KCNA5 protein CTD PMID:16129789 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 decreases activity EXP Pergolide results in decreased activity of KCNMA1 protein CTD PMID:16129789 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Msh2 mutS homolog 2 multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein] CTD PMID:15081873 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Pergolide inhibits the reaction [Hydrogen Peroxide affects the localization of NFKB1 protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of NFKB1 protein] CTD PMID:15081873 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ngf nerve growth factor increases expression
increases secretion
ISO Pergolide results in increased expression of NGF mRNA
Pergolide results in increased secretion of NGF protein
CTD PMID:12770616 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Pergolide inhibits the reaction [Hydrogen Peroxide affects the localization of RELA protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of RELA protein] CTD PMID:15081873 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Pergolide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]; Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]; Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]
Pergolide inhibits the reaction [Levodopa results in increased expression of TRP53 protein]
CTD PMID:15081873 PMID:15672541 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
pramipexole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP pramipexole inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein] CTD PMID:16362428 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP
ISO
pramipexole binds to and results in increased activity of DRD2 protein CTD PMID:10728880 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO pramipexole binds to and results in increased activity of DRD3 protein CTD PMID:10728880 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16362428 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] CTD PMID:16362428 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
pridinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pridinol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO pridinol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
procyclidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Procyclidine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Procyclidine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Ereg epiregulin increases expression ISO Procyclidine results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Procyclidine results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Procyclidine results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Procyclidine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Procyclidine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Procyclidine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Procyclidine results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Procyclidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Procyclidine results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Procyclidine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Procyclidine results in increased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
profenamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO profenamine results in decreased activity of BCHE protein
profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of acetylthiocholine iodide]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of phenyl valerate]
CTD PMID:18656440 PMID:22407886 PMID:28299395 PMID:32278739 PMID:32795450 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO profenamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
ropinirole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator increases expression ISO ropinirole results in increased expression of BCL2 protein CTD PMID:18242171 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased cleavage of CASP3 protein] CTD PMID:18242171 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased cleavage of CASP9 protein] CTD PMID:18242171 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]] CTD PMID:25053526 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO ropinirole binds to and results in increased activity of DRD2 protein CTD PMID:18393062 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO ropinirole binds to and results in increased activity of DRD3 protein CTD PMID:18242171 PMID:18393062 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions ISO ropinirole binds to and results in increased activity of DRD4 protein CTD PMID:18393062 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Egr1 early growth response 1 decreases expression EXP ropinirole results in decreased expression of EGR1 mRNA CTD PMID:20452347 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]] CTD PMID:25053526 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein] CTD PMID:18242171 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO ropinirole results in increased phosphorylation of MAPK1 protein CTD PMID:18242171 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO ropinirole results in increased phosphorylation of MAPK3 protein CTD PMID:18242171 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]] CTD PMID:25053526 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
tolcapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase decreases expression EXP tolcapone results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 increases expression EXP tolcapone results in increased expression of AARS mRNA CTD PMID:24136188 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO tolcapone results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 affects binding EXP tolcapone binds to ABCD2 protein CTD PMID:19783845 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Abhd10 abhydrolase domain containing 10, depalmitoylase affects binding EXP tolcapone binds to ABHD10 protein CTD PMID:19783845 NCBI chr11:60,053,719...60,068,142
Ensembl chr11:60,054,408...60,066,739
Ensembl chr11:60,054,408...60,066,739
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP tolcapone results in increased expression of ACAT2 mRNA CTD PMID:24136188 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl affects binding EXP tolcapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding
decreases expression
EXP
ISO
tolcapone binds to ACSL1 protein
tolcapone results in decreased expression of ACSL1 mRNA; tolcapone results in decreased expression of ACSL1 protein
CTD PMID:19783845 PMID:29688484 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO tolcapone results in decreased expression of ACSL5 protein CTD PMID:29688484 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression EXP tolcapone results in increased expression of ACSS2 mRNA CTD PMID:24136188 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acta2 actin alpha 2, smooth muscle affects binding EXP tolcapone binds to ACTA2 protein CTD PMID:19783845 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding EXP tolcapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr16:81,616,098...81,648,133
Ensembl chr16:81,616,604...81,632,030
JBrowse link
G Aga aspartylglucosaminidase decreases expression EXP tolcapone results in decreased expression of AGA mRNA CTD PMID:24136188 NCBI chr16:41,222,225...41,234,169
Ensembl chr16:41,222,238...41,234,095
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP tolcapone results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Ak2 adenylate kinase 2 affects binding EXP tolcapone binds to AK2 protein CTD PMID:19783845 NCBI chr 5:147,185,474...147,204,050
Ensembl chr 5:147,185,474...147,204,050
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 affects binding EXP Tolcapone binds to AKR1C1 protein CTD PMID:19783845 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression EXP tolcapone results in decreased expression of AKR1C3 mRNA CTD PMID:24136188 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects binding EXP tolcapone binds to AKR1D1 protein CTD PMID:19783845 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects binding EXP tolcapone binds to ALDH18A1 protein CTD PMID:19783845 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects binding EXP tolcapone binds to ALDH1B1 protein CTD