Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Yars (tyrosyl-tRNA synthetase) Mus musculus
Symbol: Yars
Name: tyrosyl-tRNA synthetase
Description: Predicted to have tyrosine-tRNA ligase activity. Predicted to be involved in tyrosyl-tRNA aminoacylation. Predicted to localize to the cytosol and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human YARS1 (tyrosyl-tRNA synthetase 1); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL024047; AU018965; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase, cytoplasmic; tyrRS
Homo sapiens (human) : YARS1 (tyrosyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Yars1 (tyrosyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yars1 (tyrosyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : YARS1 (tyrosyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : YARS1 (tyrosyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yars1 (tyrosyl-tRNA synthetase 1)
Sus scrofa (pig) : YARS1 (tyrosyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : YARS1 (tyrosyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Yars1 (tyrosyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4129,189,760 - 129,219,607 (+)Ensembl
GRCm384129,189,734 - 129,219,240 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374128,867,039 - 128,896,851 (+)NCBIGRCm37mm9NCBIm37
MGSCv364128,692,255 - 128,721,911 (+)NCBImm8
Celera4127,529,758 - 127,559,623 (+)NCBICelera
Cytogenetic Map4 D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Yars
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316915
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.