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Gene: Yars (tyrosyl-tRNA synthetase) Mus musculus
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Symbol: Yars
Name: tyrosyl-tRNA synthetase
Description: Predicted to have tyrosine-tRNA ligase activity. Predicted to be involved in tyrosyl-tRNA aminoacylation. Predicted to localize to the cytosol and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human YARS1 (tyrosyl-tRNA synthetase 1); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL024047; AU018965; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; tyrosyl-tRNA synthetase, cytoplasmic; tyrRS
Orthologs:
Homo sapiens (human) : YARS1 (tyrosyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Yars1 (tyrosyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yars1 (tyrosyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : YARS1 (tyrosyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : YARS1 (tyrosyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yars1 (tyrosyl-tRNA synthetase 1)
Sus scrofa (pig) : YARS1 (tyrosyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : YARS1 (tyrosyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Yars1 (tyrosyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4129,189,760 - 129,219,607 (+)Ensembl
GRCm384129,189,734 - 129,219,240 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374128,867,039 - 128,896,851 (+)NCBIGRCm37mm9NCBIm37
MGSCv364128,692,255 - 128,721,911 (+)NCBImm8
Celera4127,529,758 - 127,559,623 (+)NCBICelera
Cytogenetic Map4 D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Yars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316915
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.