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Gene: Apoc2 (apolipoprotein C-II) Mus musculus
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Symbol: Apoc2
Name: apolipoprotein C-II
RGD ID: 10176
Description: Predicted to have enzyme regulator activity; lipid binding activity; and phospholipase binding activity. Predicted to be involved in several processes, including lipid transport; positive regulation of lipase activity; and regulation of lipid metabolic process. Predicted to localize to several cellular components, including low-density lipoprotein particle; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Is expressed in several structures, including capillary; central nervous system; liver; lung; and yolk sac endoderm. Human ortholog(s) of this gene implicated in familial apolipoprotein C-II deficiency; familial hyperlipidemia; and multiple sclerosis. Orthologous to human APOC2 (apolipoprotein C2); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apo-CII; apoC-II; apolipoprotein C2; MGC117889
Orthologs:
Homo sapiens (human) : APOC2 (apolipoprotein C2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apoc2 (apolipoprotein C2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoc2 (apolipoprotein C2)
Pan paniscus (bonobo/pygmy chimpanzee) : APOC2 (apolipoprotein C2)
Canis lupus familiaris (dog) : APOC2 (apolipoprotein C2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoc2 (apolipoprotein C2)
Sus scrofa (pig) : APOC2 (apolipoprotein C2)
Chlorocebus sabaeus (African green monkey) : APOC2 (apolipoprotein C2)
Heterocephalus glaber (naked mole-rat) : Apoc2 (apolipoprotein C2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl719,671,579 - 19,677,941 (-)EnsemblGRCm38mm10GRCm38
GRCm38719,671,579 - 19,677,941 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,256,928 - 20,262,213 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,830,106 - 18,836,463 (-)NCBImm8
Celera717,077,835 - 17,082,947 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Apoc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10176
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.