Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) - Rat Genome Database
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Gene: Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) Mus musculus
Analyze
Symbol: Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
RGD ID: 62092
MGI Page MGI
Description: Predicted to have several functions, including 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding activity; G-protein alpha-subunit binding activity; and Gq/11-coupled serotonin receptor activity. Involved in positive regulation of fat cell differentiation; positive regulation of phosphorylation; and protein localization to cytoskeleton. Predicted to localize to several cellular components, including G protein-coupled serotonin receptor complex; cell body fiber; and integral component of synaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A); INTERACTS WITH 1,2-dichloroethane; 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-2; 5-HT-2A; 5-HT2A receptor; 5-hydroxytryptamine 2 receptor; 5-hydroxytryptamine receptor 2A; E030013E04; Htr; Htr-; Htr-2; Htr2; MGC124301; MGC124302; serotonin receptor 2A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391474,878,314 - 74,944,299 (+)NCBIGRCm39mm39
GRCm39 Ensembl1474,878,280 - 74,946,934 (+)Ensembl
GRCm381474,640,874 - 74,706,859 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1474,640,840 - 74,709,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,040,647 - 75,106,666 (+)NCBIGRCm37mm9NCBIm37
MGSCv361473,374,995 - 73,441,014 (+)NCBImm8
Celera1472,148,249 - 72,214,245 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1439.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R)-tramadol  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1-(3-chlorophenyl)piperazine  (ISO)
1-bromopropane  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (EXP)
adinazolam  (ISO)
albiflorin  (ISO)
alprenolol  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzimidazoles  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (ISO)
bisphenol F  (ISO)
bupropion  (ISO)
buspirone  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP,ISO)
cinchocaine  (ISO)
clozapine  (EXP,ISO)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
corticosterone  (ISO)
corticotropin  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
cyproheptadine  (ISO)
decabromodiphenyl ether  (ISO)
desipramine  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibenziodolium  (ISO)
dopamine  (ISO)
fenfluramine  (ISO)
fluoxetine  (EXP,ISO)
fluphenazine  (ISO)
fluvoxamine  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
Goe 6976  (ISO)
GR 127935  (ISO)
haloperidol  (ISO)
hexadecanoic acid  (ISO)
imipramine  (ISO)
ketanserin  (EXP,ISO)
lithium chloride  (ISO)
loxapine  (ISO)
metergoline  (EXP)
methamidophos  (EXP)
methamphetamine  (ISO)
methiothepin  (EXP)
mianserin  (EXP)
monocrotaline  (ISO)
N,N-dimethyltryptamine  (ISO)
N-desmethylclozapine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nitrates  (ISO)
nitrofen  (ISO)
olanzapine  (EXP,ISO)
paliperidone palmitate  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
paroxetine  (ISO)
PCB138  (ISO)
phencyclidine  (ISO)
Phenoxybenzamine  (ISO)
phorbol 12,13-dibutanoate  (ISO)
piperazines  (ISO)
poly(I:C)  (EXP)
progesterone  (ISO)
quercetin  (ISO)
quetiapine fumarate  (ISO)
raloxifene  (ISO)
risperidone  (ISO)
ritanserin  (ISO)
rotenone  (ISO)
sarpogrelate  (ISO)
SB 203580  (ISO)
SB 206553  (ISO)
serotonin  (EXP,ISO)
sertraline  (ISO)
sodium arsenite  (ISO)
spiperone  (ISO)
streptozocin  (ISO)
tamoxifen  (ISO)
tebuconazole  (ISO)
tetrachloromethane  (ISO)
tramadol  (ISO)
tributylstannane  (ISO)
tryptamine  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
yohimbine  (EXP)
zalcitabine  (EXP,ISO)
ziprasidone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of phospholipase C activity  (ISO)
aging  (ISO)
artery smooth muscle contraction  (ISO)
behavioral response to cocaine  (ISO)
cell death  (ISO)
cellular calcium ion homeostasis  (ISO)
chemical synaptic transmission  (IBA)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (IBA)
G protein-coupled serotonin receptor signaling pathway  (ISO)
memory  (ISO)
negative regulation of potassium ion transport  (ISO)
negative regulation of synaptic transmission, glutamatergic  (ISO)
phosphatidylinositol 3-kinase signaling  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IBA)
phospholipase C-activating serotonin receptor signaling pathway  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fat cell differentiation  (IMP)
positive regulation of glycolytic process  (IMP)
positive regulation of kinase activity  (IMP)
positive regulation of MAP kinase activity  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IMP)
positive regulation of phosphatidylinositol biosynthetic process  (ISO)
positive regulation of vasoconstriction  (ISO)
protein localization to cytoskeleton  (IDA)
regulation of dopamine secretion  (ISO)
regulation of synaptic vesicle exocytosis  (ISO)
release of sequestered calcium ion into cytosol  (IBA,ISO)
response to drug  (IBA,ISO)
sensory perception of pain  (ISO)
signal transduction  (IEA)
sleep  (ISO)
temperature homeostasis  (ISO)
urinary bladder smooth muscle contraction  (ISO)

References

References - curated
1. Adriani W, etal., Psychopharmacology (Berl). 2006 Jan;184(2):155-65. Epub 2005 Dec 16.
2. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
3. Castellano O, etal., Behav Brain Res. 2013 Apr 1;242:178-90. doi: 10.1016/j.bbr.2012.12.036. Epub 2013 Jan 4.
4. Hashizume H, etal., Spine. 2007 Feb 1;32(3):315-20.
5. Kobayashi S, etal., Clin Exp Nephrol. 2008 Apr;12(2):119-25. doi: 10.1007/s10157-007-0011-8. Epub 2008 Jan 5.
6. Kokubu N, etal., Circ J. 2006 Nov;70(11):1451-6.
7. Liolitsa D, etal., J Hum Hypertens. 2001 May;15(5):335-9.
8. Liu J, etal., Genomics 1991 Sep;11(1):231-4.
9. Lopez-Lopez JG, etal., J Pharmacol Exp Ther. 2011 Jul;338(1):400-7. Epub 2011 Apr 26.
10. MGD and Homologene mouse data transfer
11. MGD data from the GO Consortium
12. Ogawa T, etal., Eur J Pharmacol. 2005 Oct 3;521(1-3):156-63. Epub 2005 Sep 22.
13. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
14. OMIM Disease Annotation Pipeline
15. Pichon X, etal., Mol Ther. 2010 Aug;18(8):1462-70. doi: 10.1038/mt.2010.101. Epub 2010 Jun 8.
16. Qvigstad E, etal., Circ Res. 2005 Aug 5;97(3):268-76. Epub 2005 Jul 7.
17. RGD automated import pipeline
18. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. RGD automated import pipeline for gene-chemical interactions
20. Sakai T, etal., Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F1020-7. doi: 10.1152/ajprenal.00365.2012. Epub 2013 Jan 23.
21. Santos JL, etal., Nutr Neurosci. 2005 Aug;8(4):207-11.
22. Sugimoto Y, etal., Biol Pharm Bull. 2002 Oct;25(10):1364-6.
23. Suwazono Y, etal., Int J Mol Med. 2006 Jan;17(1):77-82.
24. Takahashi T, etal., Diabetes Res Clin Pract. 2002 Nov;58(2):123-9.
25. Yamada J, etal., Eur J Pharmacol. 1997 Apr 4;323(2-3):235-40.
26. Yu BN, etal., Clin Exp Pharmacol Physiol. 2004 Dec;31(12):847-9.
Additional References at PubMed
PMID:1323014   PMID:1333538   PMID:1381232   PMID:1980030   PMID:2032718   PMID:7558022   PMID:7582481   PMID:8626761   PMID:8672130   PMID:8747920   PMID:8833241   PMID:8833759  
PMID:9027485   PMID:9109526   PMID:9165122   PMID:9241279   PMID:9415715   PMID:9465310   PMID:10087302   PMID:10349636   PMID:10454512   PMID:10627607   PMID:10799679   PMID:10978843  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11390667   PMID:11801601   PMID:11960784   PMID:12097814   PMID:12477932   PMID:12486201   PMID:12614326   PMID:12682061   PMID:12761567  
PMID:12867255   PMID:12887695   PMID:14523084   PMID:14754868   PMID:14988405   PMID:15590675   PMID:15932887   PMID:16141072   PMID:16141073   PMID:16339018   PMID:16602821   PMID:16648258  
PMID:16873667   PMID:16884969   PMID:16902991   PMID:17097612   PMID:17250964   PMID:17270739   PMID:17408640   PMID:17537836   PMID:17684015   PMID:17720578   PMID:17888573   PMID:18195357  
PMID:18297054   PMID:18483284   PMID:18516987   PMID:18675814   PMID:18783379   PMID:19019202   PMID:19041748   PMID:19269287   PMID:19322172   PMID:19353636   PMID:19426283   PMID:19563850  
PMID:19646988   PMID:19728996   PMID:19737523   PMID:20006646   PMID:20128812   PMID:20345894   PMID:20399747   PMID:20413853   PMID:20719859   PMID:20802802   PMID:20926677   PMID:20942998  
PMID:21070242   PMID:21118683   PMID:21276828   PMID:21289196   PMID:21340474   PMID:21664256   PMID:21789169   PMID:21821099   PMID:21873635   PMID:22118459   PMID:22119732   PMID:22318950  
PMID:22531372   PMID:22569571   PMID:22609381   PMID:22640814   PMID:22692564   PMID:22722027   PMID:22864611   PMID:22871913   PMID:22975078   PMID:23045337   PMID:23119095   PMID:23129762  
PMID:23346101   PMID:23372779   PMID:23376711   PMID:23411676   PMID:23440396   PMID:23508685   PMID:23933143   PMID:24570000   PMID:24801750   PMID:24894823   PMID:24952961   PMID:25034809  
PMID:25087754   PMID:25416380   PMID:25602134   PMID:25637489   PMID:25857407   PMID:26053401   PMID:26080602   PMID:26158621   PMID:26590419   PMID:26621247   PMID:26758213   PMID:26903620  
PMID:27114257   PMID:27422820   PMID:28031476   PMID:28258217   PMID:28485378   PMID:28591153   PMID:28735749   PMID:28783139   PMID:28807414   PMID:29568676   PMID:29917056   PMID:30367948  
PMID:30446669   PMID:30685409   PMID:30716416   PMID:30755421   PMID:30770253   PMID:31072928   PMID:31505254   PMID:31704949   PMID:31787571   PMID:31806625  


Genomics

Comparative Map Data
Htr2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391474,878,314 - 74,944,299 (+)NCBIGRCm39mm39
GRCm39 Ensembl1474,878,280 - 74,946,934 (+)Ensembl
GRCm381474,640,874 - 74,706,859 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1474,640,840 - 74,709,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,040,647 - 75,106,666 (+)NCBIGRCm37mm9NCBIm37
MGSCv361473,374,995 - 73,441,014 (+)NCBImm8
Celera1472,148,249 - 72,214,245 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1439.37NCBI
HTR2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1346,831,546 - 46,897,076 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1346,831,550 - 46,897,076 (-)EnsemblGRCh38hg38GRCh38
GRCh381346,831,546 - 46,898,082 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371347,405,681 - 47,472,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361346,305,514 - 46,368,176 (-)NCBINCBI36hg18NCBI36
Build 341346,305,513 - 46,368,176NCBI
Celera1328,463,441 - 28,527,123 (-)NCBI
Cytogenetic Map13q14.2NCBI
HuRef1328,199,237 - 28,264,796 (-)NCBIHuRef
CHM1_11347,373,460 - 47,438,997 (-)NCBICHM1_1
Htr2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21549,950,035 - 50,022,188 (+)NCBI
Rnor_6.0 Ensembl1556,666,012 - 56,735,382 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01556,666,152 - 56,732,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01560,388,557 - 60,454,874 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41555,463,743 - 55,532,293 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11555,479,522 - 55,548,073NCBI
Celera1549,584,210 - 49,652,169 (+)NCBICelera
Cytogenetic Map15q11NCBI
Htr2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955431580,713 - 647,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955431583,165 - 646,991 (-)NCBIChiLan1.0ChiLan1.0
HTR2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11346,694,273 - 46,759,826 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1346,694,273 - 46,759,826 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01327,976,415 - 28,042,941 (-)NCBIMhudiblu_PPA_v0panPan3
HTR2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1224,453,715 - 4,510,934 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl224,453,715 - 4,511,037 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha224,498,607 - 4,555,448 (+)NCBI
ROS_Cfam_1.0224,566,315 - 4,626,240 (+)NCBI
UMICH_Zoey_3.1224,348,779 - 4,405,847 (+)NCBI
UNSW_CanFamBas_1.0224,412,667 - 4,469,478 (+)NCBI
UU_Cfam_GSD_1.0224,417,008 - 4,474,072 (+)NCBI
Htr2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_024404945156,850,452 - 156,910,669 (-)NCBI
SpeTri2.0NW_004936565335,238 - 394,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1120,555,961 - 20,619,629 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11120,555,939 - 20,620,225 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21120,895,106 - 20,956,369 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HTR2A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1324,820,029 - 24,884,472 (-)NCBI
ChlSab1.1 Ensembl324,820,035 - 24,883,432 (-)Ensembl
Htr2a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247488,154,288 - 8,223,226 (+)NCBI

Position Markers
Htr2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371475,105,809 - 75,106,007UniSTSGRCm37
Celera1472,213,388 - 72,213,586UniSTS
Cytogenetic Map14D2UniSTS
cM Map1441.5UniSTS
cM Map1441.5UniSTS
cM Map1441.5UniSTS
Htr2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381474,706,002 - 74,706,200UniSTSGRCm38
MGSCv371475,105,809 - 75,106,007UniSTSGRCm37
Celera1472,213,388 - 72,213,586UniSTS
Cytogenetic Map14D2UniSTS
cM Map1441.5UniSTS
Htr2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14D2UniSTS
cM Map1441.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144272496776725144Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144272496776725144Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144279982176799969Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144282839876828596Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144282839876828596Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144921797683218107Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145204453586044676Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145352385687524089Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145370000087700000Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145584494189845069Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145630930590309501Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1457942183101622037Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146216002096160240Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1469834541103834541Mouse
10054475Ossc3_mosteosarcoma susceptibility 3 (mouse)Not determined1470626332104626490Mouse
1300551Lprm3_mlymphoproliferation modifier 3 (mouse)Not determined1470983788104983908Mouse
1301844Pgia29_mproteoglycan induced arthritis 29 (mouse)Not determined1474114860108114948Mouse
1558819Ossc2_mosteosarcoma susceptibility 2 (mouse)Not determined1474157540108157657Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:119
Interacting mature miRNAs:130
Transcripts:ENSMUST00000036653
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000036653   ⟹   ENSMUSP00000047774
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1474,640,840 - 74,709,494 (+)Ensembl
RefSeq Acc Id: NM_172812   ⟹   NP_766400
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391474,878,314 - 74,944,299 (+)NCBI
GRCm381474,640,874 - 74,706,859 (+)NCBI
MGSCv371475,040,647 - 75,106,666 (+)RGD
Celera1472,148,249 - 72,214,245 (+)RGD
cM Map14 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_766400   ⟸   NM_172812
- UniProtKB: P35363 (UniProtKB/Swiss-Prot),   Q543D4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000047774   ⟸   ENSMUST00000036653
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:8682974
Promoter ID:EPDNEW_M19518
Type:initiation region
Name:Htr2a_1
Description:Mus musculus 5-hydroxytryptamine receptor 2A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19519  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381474,640,877 - 74,640,937EPDNEW
RGD ID:8682976
Promoter ID:EPDNEW_M19519
Type:initiation region
Name:Htr2a_2
Description:Mus musculus 5-hydroxytryptamine receptor 2A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19518  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381474,641,308 - 74,641,368EPDNEW
RGD ID:6825067
Promoter ID:MM_KWN:17452
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   MEF_B4,   MEF_B6
Transcripts:NM_172812
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361475,040,854 - 75,041,354 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109521 AgrOrtholog
Ensembl Genes ENSMUSG00000034997 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000047774 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036653 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro 5HT2A_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5HT_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15558 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:109521 ENTREZGENE
NCBI Gene 15558 ENTREZGENE
PANTHER PTHR24247:SF30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB HTR2A RGD
PhenoGen Htr2a PhenoGen
PRINTS 5HT2ARECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5HTRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 5HT2A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q543D4 ENTREZGENE, UniProtKB/TrEMBL