Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) Mus musculus
Analyze
Symbol: Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Description: Predicted to have several functions, including 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding activity; G-protein alpha-subunit binding activity; and serotonin binding activity. Involved in positive regulation of fat cell differentiation; positive regulation of phosphorylation; and protein localization to cytoskeleton. Predicted to localize to several cellular components, including the cell body fiber; dendritic shaft; and integral component of synaptic membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Is expressed in several structures, including brain; eye; genitourinary system; gut; and limb segment. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A); INTERACTS WITH 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine; acrylamide; alprenolol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-2; 5-HT-2A; 5-HT2A receptor; 5-hydroxytryptamine 2 receptor; 5-hydroxytryptamine receptor 2A; E030013E04; Htr-2; Htr2; MGC124301; MGC124302; serotonin receptor 2A
Orthologs:
Homo sapiens (human) : HTR2A (5-hydroxytryptamine receptor 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr2a (5-hydroxytryptamine receptor 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr2a (5-hydroxytryptamine receptor 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR2A (5-hydroxytryptamine receptor 2A)
Canis lupus familiaris (dog) : HTR2A (5-hydroxytryptamine receptor 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr2a (5-hydroxytryptamine receptor 2A)
Sus scrofa (pig) : HTR2A (5-hydroxytryptamine receptor 2A)
Chlorocebus sabaeus (green monkey) : HTR2A (5-hydroxytryptamine receptor 2A)
Heterocephalus glaber (naked mole-rat) : Htr2a (5-hydroxytryptamine receptor 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1474,640,840 - 74,709,494 (+)Ensembl
GRCm381474,640,874 - 74,706,859 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371475,040,647 - 75,106,666 (+)NCBIGRCm37mm9NCBIm37
MGSCv361473,374,995 - 73,441,014 (+)NCBImm8
Celera1472,148,249 - 72,214,245 (+)NCBICelera
Cytogenetic Map14 D3NCBI
cM Map1439.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Htr2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62092
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.