(R,R)-tramadol increases activity ISO Htr2a (Rattus norvegicus) 6480464 Tramadol results in increased activity of HTR2A protein CTD PMID:18417104 (R,R)-tramadol increases expression ISO Htr2a (Rattus norvegicus) 6480464 Tramadol results in increased expression of HTR2A mRNA CTD PMID:18417104 (R,R)-tramadol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Ketanserin inhibits the reaction [Tramadol results in increased activity of HTR2A protein] CTD PMID:18417104 (S)-nicotine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Nicotine co-treated with Benzo(a)pyrene] results in decreased expression of HTR2A protein and Nicotine results in increased activity of [HTR1B protein binds to HTR2A protein] CTD PMID:21316381 and PMID:30247698 (S)-nicotine increases expression ISO Htr2a (Rattus norvegicus) 6480464 Nicotine results in increased expression of HTR2A protein CTD PMID:30247698 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of HTR2A mRNA CTD PMID:28960355 1-(3-chlorophenyl)piperazine increases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in increased susceptibility to 1-(3-chlorophenyl)piperazine CTD PMID:16314884 1-(3-chlorophenyl)piperazine multiple interactions ISO HTR2A (Homo sapiens) 6480464 1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2A protein CTD PMID:16314884 1-(3-chlorophenyl)piperazine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to 1-(3-chlorophenyl)piperazine CTD PMID:16314884 1-bromopropane decreases expression ISO Htr2a (Rattus norvegicus) 6480464 1-bromopropane results in decreased expression of HTR2A mRNA CTD PMID:19576243 17beta-estradiol affects expression ISO Htr2a (Rattus norvegicus) 6480464 Estradiol affects the expression of HTR2A mRNA CTD PMID:12008023 17beta-estradiol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Estradiol co-treated with Sertraline] affects the expression of HTR2A mRNA and Estradiol promotes the reaction [Sertraline results in increased expression of HTR2A mRNA] CTD PMID:18650020 17beta-estradiol 3-benzoate multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA] and Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein] CTD PMID:17398000 17beta-estradiol 3-benzoate increases expression ISO Htr2a (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased expression of HTR2A mRNA and estradiol 3-benzoate results in increased expression of HTR2A protein CTD PMID:17398000 2,2',5,5'-tetrachlorobiphenyl increases expression ISO Htr2a (Rattus norvegicus) 6480464 2 more ... CTD PMID:23829299 2,2',5,5'-tetrachlorobiphenyl increases expression ISO HTR2A (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of HTR2A mRNA CTD PMID:32109520 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Htr2a (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Htr2a (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA CTD PMID:23537331 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 4-iodo-2 more ... CTD PMID:10773215 more ... 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine affects binding ISO HTR2A (Homo sapiens) 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine binds to HTR2A protein CTD PMID:9857084 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine affects response to substance ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein affects the susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine CTD PMID:22983118 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases activity ISO Htr2a (Rattus norvegicus) 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein CTD PMID:18622176 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine CTD PMID:16314884 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine decreases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in decreased susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine CTD PMID:16314884 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases response to substance EXP 6480464 HTR2A protein results in increased susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine CTD PMID:8392199 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO HTR2A (Homo sapiens) 6480464 1-(8-bromobenzo(1 more ... CTD PMID:16314884 and PMID:9857084 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions EXP 6480464 4-iodo-2 more ... CTD PMID:29748632 and PMID:8392199 3,4-methylenedioxymethamphetamine affects response to substance ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein affects the susceptibility to N-Methyl-3 and 4-methylenedioxyamphetamine CTD PMID:22983118 3,4-methylenedioxymethamphetamine multiple interactions ISO HTR2A (Homo sapiens) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:29458138 3,4-methylenedioxymethamphetamine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of HTR2A protein CTD PMID:26068050 3,5,6-trichloro-2-pyridinol multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3,5,6-trichloropyridine-2-one multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione increases expression ISO Htr2a (Rattus norvegicus) 6480464 bisindolylmaleimide I results in increased expression of HTR2A mRNA CTD PMID:22791651 3-phenoxybenzoic acid multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3H-1,2-dithiole-3-thione increases expression ISO Htr2a (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in increased expression of HTR2A mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of HTR2A exon CTD PMID:33297965 4,4'-sulfonyldiphenol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of HTR2A mRNA CTD PMID:36041667 6-propyl-2-thiouracil increases expression ISO Htr2a (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of HTR2A mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of HTR2A mRNA CTD PMID:25825206 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of HTR2A mRNA CTD PMID:30807115 adinazolam decreases expression ISO Htr2a (Rattus norvegicus) 6480464 adinazolam results in decreased expression of HTR2A protein CTD PMID:1664741 albiflorin affects expression ISO Htr2a (Rattus norvegicus) 6480464 albiflorin affects the expression of HTR2A CTD PMID:26475043 alprenolol multiple interactions EXP 6480464 [Alprenolol co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine] CTD PMID:8392199 ammonium chloride affects expression ISO Htr2a (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of HTR2A mRNA CTD PMID:16483693 amphetamine increases expression ISO Htr2a (Rattus norvegicus) 6480464 Amphetamine results in increased expression of HTR2A mRNA CTD PMID:30779732 aripiprazole decreases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in decreased susceptibility to Aripiprazole CTD PMID:16314884 aripiprazole affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to Aripiprazole CTD PMID:16314884 aripiprazole multiple interactions ISO HTR2A (Homo sapiens) 6480464 Aripiprazole binds to and results in decreased activity of HTR2A protein more ... CTD PMID:16314884 and PMID:21823597 aristolochic acid A increases expression ISO HTR2A (Homo sapiens) 6480464 aristolochic acid I results in increased expression of HTR2A mRNA CTD PMID:33212167 arsane affects methylation ISO HTR2A (Homo sapiens) 6480464 Arsenic affects the methylation of HTR2A gene CTD PMID:25304211 arsenic atom affects methylation ISO HTR2A (Homo sapiens) 6480464 Arsenic affects the methylation of HTR2A gene CTD PMID:25304211 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of HTR2A mRNA CTD PMID:33053406 Bardoxolone methyl decreases activity ISO HTR2A (Homo sapiens) 6480464 bardoxolone methyl results in decreased activity of HTR2A protein CTD PMID:28790194 benzimidazoles affects binding ISO Htr2a (Rattus norvegicus) 6480464 Benzimidazoles analog binds to HTR2A protein CTD PMID:21509803 benzo[a]pyrene increases expression ISO Htr2a (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of HTR2A protein CTD PMID:30247698 benzo[a]pyrene multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Nicotine co-treated with Benzo(a)pyrene] results in decreased expression of HTR2A protein CTD PMID:30247698 benzo[a]pyrene increases methylation ISO HTR2A (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of HTR2A exon and Benzo(a)pyrene results in increased methylation of HTR2A promoter CTD PMID:27901495 benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of HTR2A mRNA CTD PMID:26377693 bisphenol A decreases expression ISO Htr2a (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of HTR2A mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of HTR2A mRNA CTD PMID:36041667 bisphenol A multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 bisphenol F decreases expression ISO Htr2a (Rattus norvegicus) 6480464 4 and 4'-bisphenol F results in decreased expression of HTR2A mRNA CTD PMID:26186136 bisphenol F multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of HTR2A mRNA CTD PMID:36041667 bupropion multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Bupropion inhibits the reaction [Adrenocorticotropic Hormone affects the expression of HTR2A mRNA] CTD PMID:18239281 buspirone decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Buspirone results in decreased expression of HTR2A protein CTD PMID:1664741 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 calcium atom multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 calcium(0) multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO HTR2A (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to HTR2A gene] CTD PMID:28238834 chlorpyrifos increases expression ISO Htr2a (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of HTR2A more ... CTD PMID:17035140 more ... chlorpyrifos multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Chlorpyrifos results in increased expression of HTR2A mRNA] CTD PMID:35448458 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of HTR2A mRNA CTD PMID:29156651 cinchocaine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Dibucaine inhibits the reaction [Paraquat affects the localization of HTR2A protein] CTD PMID:25947082 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of HTR2A protein CTD PMID:34560070 cisplatin increases expression ISO HTR2A (Homo sapiens) 6480464 Cisplatin results in increased expression of HTR2A mRNA and Cisplatin results in increased expression of HTR2A protein CTD PMID:34560070 clozapine affects binding ISO HTR2A (Homo sapiens) 6480464 Clozapine analog binds to HTR2A protein and Clozapine binds to HTR2A protein CTD PMID:11997696 more ... clozapine multiple interactions ISO HTR2A (Homo sapiens) 6480464 Clozapine binds to and results in decreased activity of HTR2A protein and Clozapine inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:16314884 and PMID:20521326 clozapine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Clozapine results in decreased expression of HTR2A mRNA and Clozapine results in decreased expression of HTR2A protein CTD PMID:14751426 and PMID:17868938 clozapine decreases activity ISO Htr2a (Rattus norvegicus) 6480464 Clozapine results in decreased activity of HTR2A protein CTD PMID:15380371 clozapine affects binding ISO Htr2a (Rattus norvegicus) 6480464 Clozapine binds to HTR2A protein CTD PMID:9723970 clozapine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:15380371 and PMID:18976543 clozapine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to Clozapine CTD PMID:16314884 clozapine increases expression EXP 6480464 Clozapine results in increased expression of HTR2A mRNA CTD PMID:15542763 clozapine increases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in increased susceptibility to Clozapine CTD PMID:16314884 Clozapine N-oxide decreases expression ISO Htr2a (Rattus norvegicus) 6480464 clozapine N-oxide results in decreased expression of HTR2A protein CTD PMID:14751426 cocaine multiple interactions EXP 6480464 [alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine more ... CTD PMID:10764922 and PMID:8392199 cocaine affects activity ISO Htr2a (Rattus norvegicus) 6480464 Cocaine affects the activity of HTR2A protein CTD PMID:10773215 and PMID:17259860 cocaine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Cocaine promotes the reaction [[4-iodo-2 more ... CTD PMID:10773215 cocaine affects response to substance EXP 6480464 HTR2A protein affects the susceptibility to Cocaine CTD PMID:10773209 colforsin daropate hydrochloride multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Colforsin inhibits the reaction [N-(piperidin-1-yl)-1-(2 more ... CTD PMID:22791651 corticosterone multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [alpha-cyano-(3 more ... CTD PMID:19304867 and PMID:19879056 corticosterone increases secretion ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein results in increased secretion of Corticosterone CTD PMID:19304867 corticosterone increases expression ISO Htr2a (Rattus norvegicus) 6480464 Corticosterone results in increased expression of HTR2A mRNA CTD PMID:15755911 and PMID:18363858 corticotropin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Bupropion inhibits the reaction [Adrenocorticotropic Hormone affects the expression of HTR2A mRNA] CTD PMID:18239281 corticotropin affects expression ISO Htr2a (Rattus norvegicus) 6480464 Adrenocorticotropic Hormone affects the expression of HTR2A mRNA CTD PMID:18239281 cyclosporin A multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Cyclosporine inhibits the reaction [Paraquat affects the localization of HTR2A protein] CTD PMID:25947082 cyhalothrin increases expression ISO Htr2a (Rattus norvegicus) 6480464 cyhalothrin results in increased expression of HTR2A protein CTD PMID:22366556 cyhalothrin affects expression ISO Htr2a (Rattus norvegicus) 6480464 cyhalothrin affects the expression of HTR2A mRNA CTD PMID:36126889 cypermethrin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 cypermethrin promotes the reaction [cypermethrin results in increased expression of HTR2A mRNA] and cypermethrin promotes the reaction [cypermethrin results in increased expression of HTR2A protein] CTD PMID:25288152 cypermethrin increases expression ISO Htr2a (Rattus norvegicus) 6480464 cypermethrin results in increased expression of HTR2A mRNA and cypermethrin results in increased expression of HTR2A protein CTD PMID:25288152 cyproheptadine multiple interactions ISO HTR2A (Homo sapiens) 6480464 Cyproheptadine binds to and results in decreased activity of HTR2A protein CTD PMID:17031071 DDE multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 decabromodiphenyl ether increases expression ISO Htr2a (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of HTR2A mRNA CTD PMID:23914054 desipramine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Desipramine results in decreased expression of HTR2A and Desipramine results in decreased expression of HTR2A protein CTD PMID:1664741 and PMID:2553044 dexamethasone increases expression ISO Htr2a (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of HTR2A protein CTD PMID:16160705 diazinon increases expression ISO Htr2a (Rattus norvegicus) 6480464 Diazinon results in increased expression of HTR2A mRNA and Diazinon results in increased expression of HTR2A protein CTD PMID:17035140 and PMID:17452286 diazinon multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Diazinon promotes the reaction [Ketanserin binds to HTR2A protein] CTD PMID:17035140 dibenziodolium multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 diphenyleneiodonium inhibits the reaction [Paraquat affects the localization of HTR2A protein] CTD PMID:25947082 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 Diisodecyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 dopamine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [4-iodo-2 more ... CTD PMID:10773215 fenfluramine affects binding ISO HTR2A (Homo sapiens) 6480464 Fenfluramine binds to HTR2A protein CTD PMID:10617681 fluoxetine affects response to substance EXP 6480464 HTR2A protein affects the susceptibility to Fluoxetine CTD PMID:10773209 fluoxetine affects expression ISO Htr2a (Rattus norvegicus) 6480464 Fluoxetine affects the expression of HTR2A CTD PMID:26475043 fluoxetine decreases activity EXP 6480464 Fluoxetine results in decreased activity of HTR2A protein CTD PMID:19445393 and PMID:20464512 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of HTR2A mRNA CTD PMID:21083617 fluphenazine affects binding ISO HTR2A (Homo sapiens) 6480464 Fluphenazine binds to HTR2A protein CTD PMID:17606915 fluvoxamine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP affects the susceptibility to Fluvoxamine CTD PMID:12607287 gamma-hexachlorocyclohexane increases expression ISO Htr2a (Rattus norvegicus) 6480464 Hexachlorocyclohexane results in increased expression of HTR2A mRNA CTD PMID:25572523 Geniposide increases expression EXP 6480464 geniposide results in increased expression of HTR2A mRNA CTD PMID:37311497 genistein decreases expression EXP 6480464 Genistein results in decreased expression of HTR2A mRNA CTD PMID:32186404 Goe 6976 increases expression ISO Htr2a (Rattus norvegicus) 6480464 Go 6976 results in increased expression of HTR2A mRNA CTD PMID:22791651 GR 127935 multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [[volinanserin binds to and results in decreased activity of HTR2A protein] which co-treated with GR 127935] results in decreased susceptibility to Methamphetamine and GR 127935 binds to and results in decreased activity of HTR2A protein CTD PMID:11751031 and PMID:9109356 haloperidol affects binding ISO HTR2A (Homo sapiens) 6480464 Haloperidol binds to HTR2A protein CTD PMID:7520908 haloperidol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein CTD PMID:15380371 haloperidol affects binding ISO Htr2a (Rattus norvegicus) 6480464 Haloperidol binds to HTR2A protein CTD PMID:12191584 herbicide multiple interactions ISO HTR2A (Homo sapiens) 6480464 [Herbicides results in increased abundance of Picloram] which affects the methylation of HTR2A gene CTD PMID:34516295 hexadecanoic acid increases expression ISO HTR2A (Homo sapiens) 6480464 Palmitic Acid results in increased expression of HTR2A protein CTD PMID:27133527 imipramine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Imipramine results in decreased expression of HTR2A CTD PMID:2553044 ketanserin multiple interactions ISO HTR2A (Homo sapiens) 6480464 Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein] more ... CTD PMID:16314884 more ... ketanserin decreases activity ISO HTR2A (Homo sapiens) 6480464 Ketanserin results in decreased activity of HTR2A protein CTD PMID:22048642 ketanserin affects binding EXP 6480464 Ketanserin binds to HTR2A protein CTD PMID:20600638 ketanserin affects binding ISO Htr2a (Rattus norvegicus) 6480464 Ketanserin binds to HTR2A protein CTD PMID:11927170 ketanserin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2 more ... CTD PMID:10773215 more ... ketanserin multiple interactions EXP 6480464 4-iodo-2 more ... CTD PMID:10978843 more ... ketanserin affects binding ISO HTR2A (Homo sapiens) 6480464 Ketanserin binds to HTR2A protein CTD PMID:16314884 more ... lithium chloride decreases expression ISO HTR2A (Homo sapiens) 6480464 Lithium Chloride results in decreased expression of HTR2A mRNA CTD PMID:23527032 loxapine affects binding ISO Htr2a (Rattus norvegicus) 6480464 Loxapine analog binds to HTR2A protein and Loxapine binds to HTR2A protein CTD PMID:9723970 metergoline multiple interactions EXP 6480464 [Metergoline binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine CTD PMID:10764922 metformin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Chlorpyrifos results in increased expression of HTR2A mRNA] CTD PMID:35448458 methamidophos affects activity EXP 6480464 methamidophos affects the activity of HTR2A protein CTD PMID:23596261 methamphetamine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [[volinanserin binds to and results in decreased activity of HTR2A protein] which co-treated with GR 127935] results in decreased susceptibility to Methamphetamine more ... CTD PMID:11751031 and PMID:19879056 methiothepin multiple interactions EXP 6480464 [Methiothepin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine CTD PMID:10764922 mianserin multiple interactions EXP 6480464 [Mianserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine and Mianserin binds to and results in decreased activity of HTR2A protein CTD PMID:10764922 and PMID:10978843 monocrotaline increases expression ISO Htr2a (Rattus norvegicus) 6480464 Monocrotaline results in increased expression of HTR2A mRNA CTD PMID:25460361 monocrotaline multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Monocrotaline results in increased expression of HTR2A mRNA] CTD PMID:25460361 N,N-dimethyltryptamine decreases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in decreased susceptibility to N and N-Dimethyltryptamine CTD PMID:16314884 N,N-dimethyltryptamine multiple interactions ISO HTR2A (Homo sapiens) 6480464 N and N-Dimethyltryptamine binds to and results in increased activity of HTR2A protein CTD PMID:16314884 N,N-dimethyltryptamine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to N and N-Dimethyltryptamine CTD PMID:16314884 N-desmethylclozapine decreases expression ISO HTR2A (Homo sapiens) 6480464 norclozapine results in decreased expression of HTR2A mRNA CTD PMID:14751426 N-desmethylclozapine decreases expression ISO Htr2a (Rattus norvegicus) 6480464 norclozapine results in decreased expression of HTR2A protein CTD PMID:14751426 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of HTR2A mRNA CTD PMID:17942915 N-nitrosodiethylamine multiple interactions EXP 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HTR2A mRNA] CTD PMID:17942915 nickel atom decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Nickel results in decreased expression of HTR2A mRNA CTD PMID:18835401 nicotine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Nicotine co-treated with Benzo(a)pyrene] results in decreased expression of HTR2A protein and Nicotine results in increased activity of [HTR1B protein binds to HTR2A protein] CTD PMID:21316381 and PMID:30247698 nicotine increases expression ISO Htr2a (Rattus norvegicus) 6480464 Nicotine results in increased expression of HTR2A protein CTD PMID:30247698 nitrates decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Nitrates results in decreased expression of HTR2A mRNA CTD PMID:30022042 nitrofen increases expression ISO Htr2a (Rattus norvegicus) 6480464 nitrofen results in increased expression of HTR2A mRNA and nitrofen results in increased expression of HTR2A protein CTD PMID:24888825 olanzapine multiple interactions ISO HTR2A (Homo sapiens) 6480464 olanzapine binds to and results in decreased activity of HTR2A protein CTD PMID:20521326 olanzapine affects binding EXP 6480464 olanzapine binds to HTR2A protein CTD PMID:24389121 olanzapine decreases activity ISO Htr2a (Rattus norvegicus) 6480464 olanzapine results in decreased activity of HTR2A protein CTD PMID:19304867 olanzapine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [[olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:18976543 and PMID:19304867 olanzapine affects binding ISO HTR2A (Homo sapiens) 6480464 olanzapine binds to HTR2A protein CTD PMID:16983399 paliperidone palmitate affects binding ISO HTR2A (Homo sapiens) 6480464 Paliperidone Palmitate binds to HTR2A protein CTD PMID:7520908 paliperidone palmitate affects binding ISO Htr2a (Rattus norvegicus) 6480464 Paliperidone Palmitate binds to HTR2A protein CTD PMID:22437487 paliperidone palmitate multiple interactions ISO HTR2A (Homo sapiens) 6480464 Paliperidone Palmitate binds to and results in decreased activity of HTR2A protein CTD PMID:19713555 paracetamol decreases activity ISO Htr2a (Rattus norvegicus) 6480464 Acetaminophen results in decreased activity of HTR2A protein CTD PMID:10849027 paracetamol decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of HTR2A mRNA CTD PMID:25128769 paracetamol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 sodium arsenite inhibits the reaction [Acetaminophen results in decreased expression of HTR2A mRNA] CTD PMID:25128769 paraquat decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Paraquat results in decreased expression of HTR2A mRNA CTD PMID:17077588 paraquat affects localization ISO Htr2a (Rattus norvegicus) 6480464 Paraquat affects the localization of HTR2A protein CTD PMID:25947082 paraquat multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Cyclosporine inhibits the reaction [Paraquat affects the localization of HTR2A protein] more ... CTD PMID:25947082 parathion decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Parathion results in decreased expression of HTR2A protein CTD PMID:17035140 paroxetine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene polymorphism affects the susceptibility to Paroxetine CTD PMID:17503984 PCB138 decreases expression ISO Htr2a (Rattus norvegicus) 6480464 2 more ... CTD PMID:23829299 phencyclidine decreases activity ISO Htr2a (Rattus norvegicus) 6480464 Phencyclidine results in decreased activity of HTR2A protein CTD PMID:15380371 phencyclidine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein and Clozapine promotes the reaction [Phencyclidine results in decreased activity of HTR2A protein] CTD PMID:15380371 Phenoxybenzamine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Phenoxybenzamine affects the reaction [Serotonin binds to HTR2A protein] CTD PMID:8627522 phorbol 12,13-dibutanoate multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Phorbol 12 more ... CTD PMID:22791651 picloram multiple interactions ISO HTR2A (Homo sapiens) 6480464 [Herbicides results in increased abundance of Picloram] which affects the methylation of HTR2A gene CTD PMID:34516295 piperazines affects binding ISO Htr2a (Rattus norvegicus) 6480464 Piperazines analog binds to HTR2A protein CTD PMID:21509803 poly(I:C) increases expression EXP 6480464 Poly I-C results in increased expression of HTR2A mRNA CTD PMID:24889602 progesterone increases expression ISO HTR2A (Homo sapiens) 6480464 Progesterone results in increased expression of HTR2A mRNA CTD PMID:21540246 progesterone increases expression ISO Htr2a (Rattus norvegicus) 6480464 Progesterone results in increased expression of HTR2A mRNA CTD PMID:20726854 quercetin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Monocrotaline results in increased expression of HTR2A mRNA] CTD PMID:25460361 quetiapine fumarate multiple interactions ISO HTR2A (Homo sapiens) 6480464 Quetiapine Fumarate inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:16314884 raloxifene affects expression ISO HTR2A (Homo sapiens) 6480464 Raloxifene Hydrochloride affects the expression of HTR2A mRNA CTD PMID:14699072 raloxifene multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA] and Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein] CTD PMID:17398000 risperidone affects binding ISO HTR2A (Homo sapiens) 6480464 Risperidone binds to HTR2A protein CTD PMID:7520908 risperidone multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Risperidone binds to and results in decreased activity of HTR2A protein and Risperidone inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:11927170 and PMID:16948927 risperidone multiple interactions ISO HTR2A (Homo sapiens) 6480464 HTR2A gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein] and Risperidone binds to and results in decreased activity of HTR2A protein CTD PMID:16314884 and PMID:19997080 risperidone affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to Risperidone CTD PMID:16314884 risperidone increases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in increased susceptibility to Risperidone and HTR2A protein results in increased susceptibility to Risperidone CTD PMID:16314884 and PMID:19997080 risperidone affects binding ISO Htr2a (Rattus norvegicus) 6480464 Risperidone binds to HTR2A protein CTD PMID:12191584 and PMID:22437487 ritanserin multiple interactions ISO HTR2A (Homo sapiens) 6480464 Ritanserin binds to and results in decreased activity of HTR2A protein CTD PMID:17031071 ritanserin affects binding ISO Htr2a (Rattus norvegicus) 6480464 Ritanserin binds to HTR2A protein CTD PMID:8937629 rotenone decreases expression ISO Htr2a (Rattus norvegicus) 6480464 Rotenone results in decreased expression of HTR2A mRNA CTD PMID:28374803 sarpogrelate multiple interactions ISO HTR2A (Homo sapiens) 6480464 sarpogrelate binds to and results in decreased activity of HTR2A protein more ... CTD PMID:17031071 and PMID:19672037 sarpogrelate affects binding ISO Htr2a (Rattus norvegicus) 6480464 sarpogrelate binds to HTR2A protein and sarpogrelate metabolite binds to HTR2A protein CTD PMID:8937629 sarpogrelate affects binding ISO HTR2A (Homo sapiens) 6480464 sarpogrelate binds to HTR2A protein CTD PMID:16974069 SB 203580 multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [Particulate Matter results in increased expression of HTR2A mRNA] and SB 203580 inhibits the reaction [Particulate Matter results in increased expression of HTR2A protein] CTD PMID:31199065 SB 206553 multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [volinanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [SB 206553 results in increased susceptibility to Methamphetamine] CTD PMID:11751031 serotonin decreases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in decreased susceptibility to Serotonin CTD PMID:16314884 serotonin affects response to substance ISO Htr2a (Rattus norvegicus) 6480464 HTR2A protein affects the susceptibility to Serotonin CTD PMID:16528294 and PMID:8627522 serotonin affects binding ISO Htr2a (Rattus norvegicus) 6480464 Serotonin binds to HTR2A protein CTD PMID:8627522 serotonin increases expression EXP 6480464 Serotonin results in increased expression of HTR2A mRNA CTD PMID:21083617 serotonin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in decreased abundance of Serotonin] more ... CTD PMID:16528294 more ... serotonin multiple interactions EXP 6480464 HTR2A protein affects the reaction [Serotonin affects the phosphorylation of PPP1R1B protein] CTD PMID:11880652 serotonin affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to Serotonin CTD PMID:16314884 serotonin multiple interactions ISO HTR2A (Homo sapiens) 6480464 [Serotonin binds to and results in increased activity of HTR2A protein] which results in increased expression of and results in increased secretion of IL6 protein and Serotonin binds to and results in increased activity of HTR2A protein CTD PMID:11076827 and PMID:16314884 sertraline multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [Estradiol co-treated with Sertraline] affects the expression of HTR2A mRNA and Estradiol promotes the reaction [Sertraline results in increased expression of HTR2A mRNA] CTD PMID:18650020 sertraline increases expression ISO Htr2a (Rattus norvegicus) 6480464 Sertraline results in increased expression of HTR2A mRNA CTD PMID:18650020 sodium arsenite multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 sodium arsenite inhibits the reaction [Acetaminophen results in decreased expression of HTR2A mRNA] CTD PMID:25128769 sodium arsenite decreases expression ISO Htr2a (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of HTR2A mRNA CTD PMID:25128769 spiperone multiple interactions ISO HTR2A (Homo sapiens) 6480464 Spiperone inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:2891550 streptozocin multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Streptozocin inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] CTD PMID:18622176 tamoxifen affects expression ISO HTR2A (Homo sapiens) 6480464 Tamoxifen affects the expression of HTR2A mRNA CTD PMID:14699072 tebuconazole decreases expression ISO HTR2A (Homo sapiens) 6480464 tebuconazole results in decreased expression of HTR2A mRNA CTD PMID:30458266 temozolomide decreases expression ISO HTR2A (Homo sapiens) 6480464 Temozolomide results in decreased expression of HTR2A mRNA CTD PMID:31758290 tetrachloromethane increases expression ISO Htr2a (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of HTR2A mRNA CTD PMID:12832660 and PMID:16644059 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of HTR2A mRNA and Carbon Tetrachloride results in increased expression of HTR2A protein CTD PMID:35202708 tetrachloromethane increases expression ISO HTR2A (Homo sapiens) 6480464 Carbon Tetrachloride results in increased expression of HTR2A mRNA and Carbon Tetrachloride results in increased expression of HTR2A protein CTD PMID:35202708 tramadol multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 Ketanserin inhibits the reaction [Tramadol results in increased activity of HTR2A protein] CTD PMID:18417104 tramadol increases activity ISO Htr2a (Rattus norvegicus) 6480464 Tramadol results in increased activity of HTR2A protein CTD PMID:18417104 tramadol increases expression ISO Htr2a (Rattus norvegicus) 6480464 Tramadol results in increased expression of HTR2A mRNA CTD PMID:18417104 tributylstannane decreases expression ISO HTR2A (Homo sapiens) 6480464 tributyltin results in decreased expression of HTR2A mRNA CTD PMID:29580985 trichloroethene increases expression ISO Htr2a (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of HTR2A mRNA CTD PMID:33387578 tryptamine decreases response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A gene SNP results in decreased susceptibility to tryptamine CTD PMID:16314884 tryptamine affects response to substance ISO HTR2A (Homo sapiens) 6480464 HTR2A protein affects the susceptibility to tryptamine CTD PMID:16314884 tryptamine multiple interactions ISO HTR2A (Homo sapiens) 6480464 tryptamine binds to and results in increased activity of HTR2A protein CTD PMID:16314884 valproic acid decreases methylation ISO HTR2A (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of HTR2A gene CTD PMID:29154799 vincristine increases expression ISO Htr2a (Rattus norvegicus) 6480464 Vincristine results in increased expression of HTR2A protein CTD PMID:18930597 vincristine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Vincristine CTD PMID:18930597 yohimbine multiple interactions EXP 6480464 [Yohimbine co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2 and 5-dimethoxyphenylisopropylamine] CTD PMID:8392199 zalcitabine increases response to substance EXP 6480464 HTR2A gene results in increased susceptibility to Zalcitabine CTD PMID:17888573 zalcitabine multiple interactions ISO Htr2a (Rattus norvegicus) 6480464 [alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Zalcitabine CTD PMID:17888573 zalcitabine increases expression ISO Htr2a (Rattus norvegicus) 6480464 Zalcitabine results in increased expression of HTR2A protein CTD PMID:17888573 ziprasidone multiple interactions ISO HTR2A (Homo sapiens) 6480464 ziprasidone inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:16314884