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Gene: Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) Mus musculus
Symbol: Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Description: Predicted to have several functions, including 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding activity; G-protein alpha-subunit binding activity; and serotonin binding activity. Involved in positive regulation of fat cell differentiation; positive regulation of phosphorylation; and protein localization to cytoskeleton. Predicted to localize to several cellular components, including the cell body fiber; dendritic shaft; and integral component of synaptic membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Is expressed in several structures, including brain; eye; genitourinary system; gut; and limb segment. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A); INTERACTS WITH 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine; acrylamide; alprenolol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-2; 5-HT-2A; 5-HT2A receptor; 5-hydroxytryptamine 2 receptor; 5-hydroxytryptamine receptor 2A; E030013E04; Htr-2; Htr2; MGC124301; MGC124302; serotonin receptor 2A
Homo sapiens (human) : HTR2A (5-hydroxytryptamine receptor 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Htr2a (5-hydroxytryptamine receptor 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr2a (5-hydroxytryptamine receptor 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR2A (5-hydroxytryptamine receptor 2A)
Canis lupus familiaris (dog) : HTR2A (5-hydroxytryptamine receptor 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr2a (5-hydroxytryptamine receptor 2A)
Sus scrofa (pig) : HTR2A (5-hydroxytryptamine receptor 2A)
Chlorocebus sabaeus (green monkey) : HTR2A (5-hydroxytryptamine receptor 2A)
Heterocephalus glaber (naked mole-rat) : Htr2a (5-hydroxytryptamine receptor 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1474,640,840 - 74,709,494 (+)Ensembl
GRCm381474,640,874 - 74,706,859 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371475,040,647 - 75,106,666 (+)NCBIGRCm37mm9NCBIm37
MGSCv361473,374,995 - 73,441,014 (+)NCBImm8
Celera1472,148,249 - 72,214,245 (+)NCBICelera
Cytogenetic Map14 D3NCBI
cM Map1439.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Htr2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62092
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.