HTR2A (5-hydroxytryptamine receptor 2A)

Gene: HTR2A (5-hydroxytryptamine receptor 2A) Canis lupus familiaris

Analyze

Symbol:

HTR2A

Name:

5-hydroxytryptamine receptor 2A

RGD ID:

12177797

Description:

ENCODES a protein that exhibits G protein-coupled serotonin receptor activity; serotonin binding; protein tyrosine kinase activator activity (ortholog); INVOLVED IN release of sequestered calcium ion into cytosol; response to xenobiotic stimulus; artery smooth muscle contraction (ortholog); ASSOCIATED WITH Acute Stress Disorders, Traumatic (ortholog); alcohol use disorder (ortholog); alcoholic psychosis (ortholog); FOUND IN G protein-coupled serotonin receptor complex; plasma membrane; cell body fiber (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

5-HT-2; 5-HT-2A; 5-HTR2A; 5HT2A receptor; serotonin receptor 2A

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	4,453,715 - 4,510,934 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	4,453,715 - 4,511,037 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	4,498,607 - 4,555,448 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	4,566,315 - 4,626,240 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	4,565,931 - 4,625,623 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	4,348,779 - 4,405,847 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	4,412,667 - 4,469,478 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	4,417,008 - 4,474,072 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Stress Disorders, Traumatic (ISO)

alcohol dependence (ISO)

alcohol use disorder (ISO)

alcoholic psychosis (ISO)

Alzheimer's disease (ISO)

anorexia nervosa (ISO)

asthma (ISO)

autistic disorder (ISO)

Back Pain (ISO)

basal ganglia disease (ISO)

bipolar disorder (ISO)

bladder neck obstruction (ISO)

Cardiomegaly (ISO)

chronic obstructive pulmonary disease (ISO)

cocaine abuse (ISO)

cocaine dependence (ISO)

Cocaine-Related Disorders (ISO)

cognitive disorder (ISO)

congenital diaphragmatic hernia (ISO)

congestive heart failure (ISO)

depressive disorder (ISO)

Diabetic Nephropathies (ISO)

disease of metabolism (ISO)

Dyskinesias (ISO)

endotoxin shock (ISO)

Experimental Diabetes Mellitus (ISO)

Fever (ISO)

genetic disease (ISO)

Hallucinations (ISO)

Hyperalgesia (ISO)

hyperglycemia (ISO)

Hyperkinesis (ISO)

Hyperphagia (ISO)

hypertension (ISO)

Hypoxia (ISO)

inflammatory and toxic neuropathy (ISO)

Insulin Resistance (ISO)

Intervertebral Disc Displacement (ISO)

major depressive disorder (ISO)

Memory Disorders (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

migraine (ISO)

morphine dependence (ISO)

nicotine dependence (ISO)

non-alcoholic fatty liver (ISO)

obesity (ISO)

obsessive-compulsive disorder (ISO)

opioid abuse (ISO)

pancreatitis (ISO)

pathological gambling (ISO)

psychotic disorder (ISO)

schizophrenia (ISO)

Sleep Bruxism (ISO)

Sleep Initiation and Maintenance Disorders (ISO)

steatotic liver disease (ISO)

stress-related disorder (ISO)

Urinary Incontinence (ISO)

Urination Disorders (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

artery smooth muscle contraction (ISO)

behavioral response to cocaine (ISO)

chemical synaptic transmission (IBA)

detection of mechanical stimulus involved in sensory perception of pain (ISO)

detection of temperature stimulus involved in sensory perception of pain (ISO)

G protein-coupled receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (IBA)

G protein-coupled serotonin receptor signaling pathway (IEA)

glycolytic process (ISO)

intracellular calcium ion homeostasis (IEA)

memory (ISO)

negative regulation of potassium ion transport (ISO)

negative regulation of synaptic transmission, glutamatergic (ISO)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

phospholipase C-activating serotonin receptor signaling pathway (IBA,ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of cytokine production involved in immune response (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of DNA biosynthetic process (ISO)

positive regulation of ERK1 and ERK2 cascade (IEA,ISO)

positive regulation of execution phase of apoptosis (ISO)

positive regulation of fat cell differentiation (ISO)

positive regulation of glycolytic process (ISO)

positive regulation of heat generation (ISO)

positive regulation of inflammatory response (ISO)

positive regulation of MAP kinase activity (ISO)

positive regulation of neuron apoptotic process (ISO)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

positive regulation of phosphatidylinositol biosynthetic process (IEA)

positive regulation of platelet aggregation (ISO)

positive regulation of vasoconstriction (ISO)

presynaptic modulation of chemical synaptic transmission (ISO)

protein localization to cytoskeleton (ISO)

regulation of dopamine secretion (ISO)

release of sequestered calcium ion into cytosol (IBA,IDA,IEA)

response to cocaine (ISO)

response to xenobiotic stimulus (IBA,IDA,IEA,ISO)

sensitization (ISO)

sensory perception of temperature stimulus (ISO)

serotonin receptor signaling pathway (IBA)

temperature homeostasis (ISO)

urinary bladder smooth muscle contraction (ISO)

Cellular Component

axon (IEA)

caveola (IEA)

cell body fiber (ISO)

cell projection (IEA)

cytoplasmic vesicle (IEA)

dendrite (IBA,IEA,ISO)

dendritic shaft (ISO)

G protein-coupled serotonin receptor complex (IDA,IEA)

glutamatergic synapse (ISO)

neurofilament (ISO)

neuronal cell body (ISO)

plasma membrane (IBA,IDA,IEA,ISO)

postsynaptic membrane (ISO)

presynapse (IEA)

presynaptic membrane (ISO)

synapse (IEA)

Molecular Function

1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding (IEA)

G protein-coupled receptor activity (IEA)

G protein-coupled serotonin receptor activity (IBA,IDA,IEA)

Gq/11-coupled serotonin receptor activity (IEA)

identical protein binding (IEA)

neurotransmitter receptor activity (IBA)

protein binding (ISO)

protein tyrosine kinase activator activity (ISO)

protein-containing complex binding (ISO)

serotonin binding (IDA,IEA)

References

Additional References at PubMed

PMID:15353848	PMID:15862800	PMID:19922435	PMID:22301074	PMID:24330646	PMID:25843893	PMID:30032202

Genomics

Comparative Map Data

HTR2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	4,453,715 - 4,510,934 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	4,453,715 - 4,511,037 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	4,498,607 - 4,555,448 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	4,566,315 - 4,626,240 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	4,565,931 - 4,625,623 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	4,348,779 - 4,405,847 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	4,412,667 - 4,469,478 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	4,417,008 - 4,474,072 (+)	NCBI		UU_Cfam_GSD_1.0

HTR2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	46,831,546 - 46,898,082 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	46,831,546 - 46,897,076 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	47,405,681 - 47,472,217 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	46,305,514 - 46,368,176 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	46,305,513 - 46,368,176	NCBI
Celera	13	28,463,441 - 28,527,123 (-)	NCBI		Celera
Cytogenetic Map	13	q14.2	NCBI
HuRef	13	28,199,237 - 28,264,796 (-)	NCBI		HuRef
CHM1_1	13	47,373,460 - 47,438,997 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	46,052,771 - 46,119,333 (-)	NCBI		T2T-CHM13v2.0

Htr2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	74,878,314 - 74,944,299 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	74,878,280 - 74,946,934 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	74,640,874 - 74,706,859 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	74,640,840 - 74,709,494 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	75,040,647 - 75,106,666 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	73,374,995 - 73,441,014 (+)	NCBI		MGSCv36	mm8
Celera	14	72,148,249 - 72,214,245 (+)	NCBI		Celera
Cytogenetic Map	14	D3	NCBI
cM Map	14	39.37	NCBI

Htr2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	56,360,647 - 56,428,703 (+)	NCBI		GRCr8
mRatBN7.2	15	49,950,035 - 50,022,188 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	49,950,804 - 50,020,928 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	54,102,628 - 54,169,818 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	55,214,204 - 55,281,396 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	52,047,008 - 52,120,825 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	56,666,152 - 56,732,469 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	56,666,012 - 56,735,382 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	60,388,557 - 60,454,874 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	55,463,743 - 55,532,293 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	55,479,522 - 55,548,073	NCBI
Celera	15	49,584,210 - 49,652,169 (+)	NCBI		Celera
Cytogenetic Map	15	q11	NCBI

Htr2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	580,713 - 647,345 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	583,165 - 646,991 (-)	NCBI	ChiLan1.0	ChiLan1.0

HTR2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	48,275,990 - 48,342,521 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	46,927,083 - 46,993,610 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	27,976,415 - 28,042,941 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	46,694,273 - 46,759,826 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	46,694,273 - 46,759,826 (-)	Ensembl	panpan1.1		panPan2

Htr2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	156,850,452 - 156,910,669 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936565	334,393 - 394,715 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936565	335,238 - 394,683 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HTR2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	20,555,963 - 20,619,625 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	20,555,939 - 20,620,225 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	20,895,106 - 20,956,369 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HTR2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	24,820,029 - 24,884,472 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	24,820,035 - 24,883,432 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	19,114,044 - 19,177,668 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Htr2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624748	8,155,107 - 8,223,259 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624748	8,154,288 - 8,223,226 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HTR2A
516 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium
Low	3		7		6				12		3
Below cutoff	2	5	15	6		6	6	4		8	7	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001005869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038430767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB193092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY832858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y16134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000043451 ⟹ ENSCAFP00000042319

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	22	4,453,715 - 4,511,037 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000068633 ⟹ ENSCAFP00000050411

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	22	4,455,007 - 4,511,037 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845012480 ⟹ ENSCAFP00845009749

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	22	4,565,931 - 4,625,623 (+)	Ensembl

RefSeq Acc Id:

NM_001005869 ⟹ NP_001005869

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	22	4,453,715 - 4,510,934 (+)	NCBI
Dog10K_Boxer_Tasha	22	4,498,607 - 4,555,448 (+)	NCBI
ROS_Cfam_1.0	22	4,566,315 - 4,623,176 (+)	NCBI
UMICH_Zoey_3.1	22	4,348,779 - 4,405,847 (+)	NCBI
UNSW_CanFamBas_1.0	22	4,412,667 - 4,469,478 (+)	NCBI
UU_Cfam_GSD_1.0	22	4,417,008 - 4,474,072 (+)	NCBI

Sequence:

show sequence

ATGGATGTCCTCTTTGAGGATAATGCTCCTTTGAGCCCAACCACCAGCTCCTTAATGCCGTCAA
ACGGGGACCCAAGGCTCTACGGCAACGACCTGAACGCTGGAGACGCGAACACTTCGGATGCATT
TAACTGGACAGTGGATGCAGAAAACCGAACCAACCTTTCCTGCGAGGGCTGTCTCTCGCCACCA
TGCTTCTCCCTACTTCATCTCCAGGAAAAAAACTGGTCGGCTCTGTTGACAGCGGTCGTGATTA
TTCTGACCATTGCTGGAAACATACTCGTCATCATGGCAGTGTCCCTAGAGAAAAAGCTGCAGAA
CGCCACCAACTATTTCCTGATGTCACTTGCCATAGCTGATATGCTGCTGGGTTTCCTTGTCATG
CCCGTGTCCATGCTAACCATCCTATATGGTTACCGGTGGCCTCTGCCTAGCAAACTGTGCGCCG
TGTGGATCTACCTGGACGTGCTCTTCTCCACGGCCTCCATCATGCACCTGTGCGCCATCTCGCT
AGACCGCTACGTTGCCATCCAGAACCCCATCCACCATAGCCGATTCAACTCCAGAACTAAGGCA
TTTCTGAAGATCATCGCTGTCTGGACCATATCAGTGGGTATATCTATGCCAATACCAGTTTTCG
GGCTACAGGATGATTCCAAGGTCTTTAAGGAAGGGAGCTGCCTACTTGCCGACGATAACTTTGT
CCTGATCGGCTCTTTCGTGTCGTTCTTCATTCCCTTAACCATCATGGTGATCACCTACTTTCTA
ACTATCAAGTCGCTCCAGAAAGAAGCCACCTTGTGTGTGAGTGATCCTGGCACACGGGCCAAGC
TAGCGTCTTTCAGCTTCCTCCCTCAGAGCTCCCTGTCTTCGGAAAAGCTCTTCCAACGATCAAT
CCACAGGGAGCCAGGGTCCTACGGCAGGAGGACTATGCAGTCCATCAGCAATGAGCAGAAAGCT
TGCAAGGTGCTGGGCATTGTCTTCTTCCTGTTTGTGGTGATGTGGTGCCCATTCTTCATCACGA
ACATAATGGCCGTCATCTGCAAAGAGTCCTGCAACGAGGATATCATTGGAGCCCTGCTCAACGT
GTTTGTCTGGATCGGTTACCTCTCCTCGGCGGTCAACCCACTGGTATACACACTGTTCAACAAG
ACCTACAGGTCGGCCTTCTCCCGGTATATTCAGTGTCAGTACAAGGAAAATAAAAAACCATTGC
AGTTAATTTTAGTGAACACTATACCGGCCTTGGCCTACAAATCTAGTCAACTCCAAATGGGACA
AAAAAAGAATTCAAAGAAAGATGCCAAGAGCACAGATAATGACTACAGCATGGTTGCTCTAGGA
AAACAACATTCAGAAGACGCTCCTACAGACAATATTAACACAGTGAATGAAAAGGTTAGCTGTG
TGTGA

hide sequence

RefSeq Acc Id:

XM_038430765 ⟹ XP_038286693

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,566,869 - 4,626,240 (+)	NCBI

RefSeq Acc Id:

XM_038430766 ⟹ XP_038286694

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,568,057 - 4,626,240 (+)	NCBI

RefSeq Acc Id:

XM_038430767 ⟹ XP_038286695

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	22	4,566,869 - 4,626,240 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001005869	(Get FASTA)	NCBI Sequence Viewer
	XP_038286693	(Get FASTA)	NCBI Sequence Viewer
	XP_038286694	(Get FASTA)	NCBI Sequence Viewer
	XP_038286695	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAX39385	(Get FASTA)	NCBI Sequence Viewer
	BAD60922	(Get FASTA)	NCBI Sequence Viewer
	CAA76080	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000074786.1
	ENSCAFP00030038397.1
	ENSCAFP00040022022.1
	ENSCAFP00805028736
	ENSCAFP00845009749
	ENSCAFP00845009749.1
GenBank Protein	O46635	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001005869 ⟸ NM_001005869

- UniProtKB:

Q50DZ9 (UniProtKB/Swiss-Prot), Q60F96 (UniProtKB/Swiss-Prot), O46635 (UniProtKB/Swiss-Prot), A0A8C0L4N4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDVLFEDNAPLSPTTSSLMPSNGDPRLYGNDLNAGDANTSDAFNWTVDAENRTNLSCEGCLSPP
CFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVM
PVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKA
FLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFL
TIKSLQKEATLCVSDPGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKA
CKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDIIGALLNVFVWIGYLSSAVNPLVYTLFNK
TYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKKDAKSTDNDYSMVALG
KQHSEDAPTDNINTVNEKVSCV

hide sequence

RefSeq Acc Id:

ENSCAFP00000050411 ⟸ ENSCAFT00000068633

RefSeq Acc Id:

ENSCAFP00000042319 ⟸ ENSCAFT00000043451

RefSeq Acc Id:	XP_038286695 ⟸ XM_038430767
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038286693 ⟸ XM_038430765
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038286694 ⟸ XM_038430766
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSCAFP00845009749 ⟸ ENSCAFT00845012480

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000028871	Ensembl
	ENSCAFG00000045223	UniProtKB/Swiss-Prot
	ENSCAFG00030023919	UniProtKB/Swiss-Prot
	ENSCAFG00040013721	UniProtKB/Swiss-Prot
	ENSCAFG00805020274	UniProtKB/Swiss-Prot
	ENSCAFG00845007028	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00000081998.2	UniProtKB/Swiss-Prot
	ENSCAFT00030043991.1	UniProtKB/Swiss-Prot
	ENSCAFT00040025336.1	UniProtKB/Swiss-Prot
	ENSCAFT00805036659	UniProtKB/Swiss-Prot
	ENSCAFT00845012480	ENTREZGENE
	ENSCAFT00845012480.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	5HT2A_rcpt	UniProtKB/Swiss-Prot
	5HT_rcpt	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
KEGG Report	cfa:403882	UniProtKB/Swiss-Prot
NCBI Gene	HTR2A	ENTREZGENE
PANTHER	5-HYDROXYTRYPTAMINE RECEPTOR	UniProtKB/Swiss-Prot
	PTHR24247:SF30	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PRINTS	5HT2ARECEPTR	UniProtKB/Swiss-Prot
	5HTRECEPTOR	UniProtKB/Swiss-Prot
	GPCRRHODOPSN	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	5HT2A_CANLF	UniProtKB/Swiss-Prot
	A0A8C0L4N4	ENTREZGENE
	O46635	ENTREZGENE
	Q50DZ9	ENTREZGENE
	Q60F96	ENTREZGENE
UniProt Secondary	Q50DZ9	UniProtKB/Swiss-Prot
	Q60F96	UniProtKB/Swiss-Prot
VGNC ID	VGNC:110511	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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