Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dpp6 (dipeptidylpeptidase 6) Mus musculus
Symbol: Dpp6
Name: dipeptidylpeptidase 6
RGD ID: 68591
Description: Exhibits potassium channel regulator activity. Involved in neuronal action potential; positive regulation of potassium ion transmembrane transport; and protein localization to plasma membrane. Localizes to voltage-gated potassium channel complex. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; intervertebral disc; and nose. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (dipeptidyl peptidase like 6); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B930011P16Rik; D5Buc3; D5Buc4; D5Buc5; dipeptidyl aminopeptidase-like protein 6; dipeptidyl aminopeptidase-related protein; dipeptidyl peptidase IV-like protein; dipeptidyl peptidase VI; dipeptidylpeptidase VI; Dpp; DPP VI; Dpp-6; DPPX; Gm1377; In(5)6; In(5)6H-p; inversion, Chr 5, Harwell 6, proximal; MGC113720; Pe; Peplb; R; RIKEN cDNA B930011P16 gene; Rw
Homo sapiens (human) : DPP6 (dipeptidyl peptidase like 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dpp6 (dipeptidyl peptidase like 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpp6 (dipeptidyl peptidase like 6)
Pan paniscus (bonobo/pygmy chimpanzee) : DPP6 (dipeptidyl peptidase like 6)
Canis lupus familiaris (dog) : DPP6 (dipeptidyl peptidase like 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpp6 (dipeptidyl peptidase like 6)
Sus scrofa (pig) : DPP6 (dipeptidyl peptidase like 6)
Chlorocebus sabaeus (African green monkey) : DPP6 (dipeptidyl peptidase like 6)
Heterocephalus glaber (naked mole-rat) : Dpp6 (dipeptidyl peptidase like 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39527,022,355 - 27,932,498 (+)NCBI
GRCm38526,817,357 - 27,727,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl526,817,203 - 27,727,505 (+)EnsemblGRCm38mm10GRCm38
MGSCv37527,143,897 - 28,054,040 (+)NCBIGRCm37mm9NCBIm37
MGSCv36527,148,144 - 28,057,245 (+)NCBImm8
Celera524,366,865 - 25,273,913 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map512.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dpp6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68591
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.