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Gene: Gna12 (guanine nucleotide binding protein, alpha 12) Mus musculus
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Symbol: Gna12
Name: guanine nucleotide binding protein, alpha 12
Description: Predicted to have D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including Rho protein signal transduction; embryonic digit morphogenesis; and regulation of fibroblast migration. Predicted to localize to the brush border membrane and heterotrimeric G-protein complex. Is expressed in several structures, including branchial arch; central nervous system; female reproductive system; heart; and retina. Orthologous to human GNA12 (G protein subunit alpha 12); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-trichloroethane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AI414047; AI504261; g alpha-12; G-protein subunit alpha-12; Galpha12; guanine nucleotide-binding protein subunit alpha-12; MGC130498
Orthologs:
Homo sapiens (human) : GNA12 (G protein subunit alpha 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gna12 (G protein subunit alpha 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gna12 (G protein subunit alpha 12)
Pan paniscus (bonobo/pygmy chimpanzee) : GNA12 (G protein subunit alpha 12)
Canis lupus familiaris (dog) : GNA12 (G protein subunit alpha 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gna12 (G protein subunit alpha 12)
Sus scrofa (pig) : GNA12 (G protein subunit alpha 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm385140,759,944 - 140,830,431 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375141,235,898 - 141,306,385 (-)NCBIGRCm37mm9NCBIm37
MGSCv365141,012,418 - 141,082,905 (-)NCBImm8
Celera5137,821,586 - 137,847,257 (-)NCBICelera
Cytogenetic Map5 G2NCBI
cM Map579.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gna12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732492
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.