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Gene: Gna12 (guanine nucleotide binding protein, alpha 12) Mus musculus
Symbol: Gna12
Name: guanine nucleotide binding protein, alpha 12
Description: Predicted to have D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including Rho protein signal transduction; embryonic digit morphogenesis; and regulation of fibroblast migration. Predicted to localize to the brush border membrane and heterotrimeric G-protein complex. Is expressed in several structures, including branchial arch; central nervous system; female reproductive system; heart; and retina. Orthologous to human GNA12 (G protein subunit alpha 12); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-trichloroethane; 17beta-estradiol.
Type: protein-coding
Also known as: AI414047; AI504261; g alpha-12; G-protein subunit alpha-12; Galpha12; guanine nucleotide-binding protein subunit alpha-12; MGC130498
Homo sapiens (human) : GNA12 (G protein subunit alpha 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gna12 (G protein subunit alpha 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gna12 (G protein subunit alpha 12)
Pan paniscus (bonobo/pygmy chimpanzee) : GNA12 (G protein subunit alpha 12)
Canis lupus familiaris (dog) : GNA12 (G protein subunit alpha 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gna12 (G protein subunit alpha 12)
Sus scrofa (pig) : GNA12 (G protein subunit alpha 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm385140,759,944 - 140,830,431 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375141,235,898 - 141,306,385 (-)NCBIGRCm37mm9NCBIm37
MGSCv365141,012,418 - 141,082,905 (-)NCBImm8
Celera5137,821,586 - 137,847,257 (-)NCBICelera
Cytogenetic Map5 G2NCBI
cM Map579.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gna12
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732492
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.