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Gene: Hspa1a (heat shock protein 1A) Mus musculus
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Symbol: Hspa1a
Name: heat shock protein 1A
Description: Exhibits protein folding chaperone. Involved in several processes, including DNA metabolic process; lysosomal transport; and response to heat. Localizes to the cytoplasm. Predicted to colocalize with the COP9 signalosome. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune hypersensitivity disease (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Is expressed in several structures, including adrenal gland; early conceptus; genitourinary system; and vibrissa. Orthologous to several human genes including HSPA1B (heat shock protein family A (Hsp70) member 1B); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 68 kDa heat shock protein; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 3; heat shock 70kDa protein 1A; heat shock protein, 70 kDa 3; hsp68; Hsp70; Hsp70-3; Hsp70.3; hsp70A1; Hsp72; inducible heat shock protein 70; MGC189852
Orthologs:
Homo sapiens (human) : HSPA1A (heat shock protein family A (Hsp70) member 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hspa1a (heat shock protein family A (Hsp70) member 1A)  Alliance
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa1a (heat shock protein family A (Hsp70) member 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381734,969,359 - 34,972,156 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371735,106,304 - 35,109,101 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,577,246 - 34,580,180 (-)NCBImm8
Celera1738,065,583 - 38,068,380 (-)NCBICelera
Cytogenetic Map17 B1NCBI
cM Map1718.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hspa1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558069
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.