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Gene: Mtdh (metadherin) Mus musculus
Symbol: Mtdh
Name: metadherin
Description: Predicted to have double-stranded RNA binding activity; transcription coactivator activity; and transcription factor binding activity. Predicted to be involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of transcription, DNA-templated. Localizes to several cellular components, including the endoplasmic reticulum membrane; nucleolus; and perinuclear region of cytoplasm. Is expressed in several structures, including brain; genitourinary system; limb; nose; and skin. Orthologous to human MTDH (metadherin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; deoxynivalenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610103J23Rik; 3D3; 3D3/Lyric; AEG-1; AV353288; D8Bwg1112e; Lyric; lysine-rich CEACAM1 co-isolated protein; metastasis adhesion protein
Homo sapiens (human) : MTDH (metadherin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mtdh (metadherin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtdh (metadherin)
Pan paniscus (bonobo/pygmy chimpanzee) : MTDH (metadherin)
Canis lupus familiaris (dog) : MTDH (metadherin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtdh (metadherin)
Sus scrofa (pig) : MTDH (metadherin)
Chlorocebus sabaeus (green monkey) : MTDH (metadherin)
Heterocephalus glaber (naked mole-rat) : Mtdh (metadherin)
more info ...
Related Pseudogenes: Gm17850   Gm3836  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1534,082,694 - 34,145,624 (+)Ensembl
GRCm381534,082,442 - 34,143,537 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371534,012,474 - 34,072,140 (+)NCBIGRCm37mm9NCBIm37
MGSCv361534,027,370 - 34,085,968 (+)NCBImm8
Celera1534,707,184 - 34,766,810 (+)NCBICelera
Cytogenetic Map15 B3.1NCBI
cM Map1513.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mtdh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332296
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.