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Gene: Amfr (autocrine motility factor receptor) Mus musculus
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Symbol: Amfr
Name: autocrine motility factor receptor
RGD ID: 1323069
Description: Predicted to have several functions, including BAT3 complex binding activity; chaperone binding activity; and ubiquitin-specific protease binding activity. Involved in negative regulation of canonical Wnt signaling pathway and regulation of SREBP signaling pathway. Predicted to localize to several cellular components, including endoplasmic reticulum membrane; growth cone; and neuronal cell body. Is expressed in several structures, including central nervous system; genitourinary system; integumental system; liver; and retina nuclear layer. Orthologous to human AMFR (autocrine motility factor receptor); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AMF receptor; E3 ubiquitin-protein ligase AMFR; gp7; gp78; RING-type E3 ubiquitin transferase AMFR
Orthologs:
Homo sapiens (human) : AMFR (autocrine motility factor receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Amfr (autocrine motility factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amfr (autocrine motility factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : AMFR (autocrine motility factor receptor)
Canis lupus familiaris (dog) : AMFR (autocrine motility factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amfr (autocrine motility factor receptor)
Sus scrofa (pig) : AMFR (autocrine motility factor receptor)
Chlorocebus sabaeus (African green monkey) : AMFR (autocrine motility factor receptor)
Heterocephalus glaber (naked mole-rat) : Amfr (autocrine motility factor receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39894,698,216 - 94,739,268 (-)NCBI
GRCm38893,971,588 - 94,012,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl893,971,588 - 94,012,842 (-)EnsemblGRCm38mm10GRCm38
MGSCv37896,495,488 - 96,536,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv36896,861,055 - 96,901,971 (-)NCBImm8
Celera898,301,641 - 98,335,290 (-)NCBICelera
Cytogenetic Map8C5NCBI
cM Map845.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Amfr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323069
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.