Ctnnb1 (catenin (cadherin associated protein), beta 1) - Rat Genome Database

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Gene: Ctnnb1 (catenin (cadherin associated protein), beta 1) Mus musculus
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Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
RGD ID: 1550466
MGI Page MGI
Description: Enables several functions, including alpha-catenin binding activity; disordered domain specific binding activity; and enzyme binding activity. Involved in several processes, including canonical Wnt signaling pathway; nervous system development; and regulation of gene expression. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and negative regulation of cell differentiation. Located in several cellular components, including Schaffer collateral - CA1 synapse; apicolateral plasma membrane; and basolateral plasma membrane. Part of several cellular components, including Scrib-APC-beta-catenin complex; Wnt signalosome; and beta-catenin destruction complex. Is active in postsynaptic density, intracellular component and postsynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Used to study autism spectrum disorder; granulosa cell tumor; ovarian cancer; prostate cancer; and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); nephroblastoma; and pilomatrixoma. Orthologous to human CTNNB1 (catenin beta 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-catenin; Bfc; Cat; catenin beta-1; Catnb; Mesc
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,762,466 - 120,789,573 (+)NCBIGRCm39mm39
GRCm39 Ensembl9120,758,282 - 120,789,573 (+)Ensembl
GRCm389120,933,400 - 120,960,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,929,216 - 120,960,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,842,518 - 120,869,625 (+)NCBIGRCm37mm9NCBIm37
MGSCv369120,782,173 - 120,809,205 (+)NCBImm8
Celera9121,404,098 - 121,431,499 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model