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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Butylated Hydroxytoluene co-treated with Oxygen] affects the localization of CTNNB1 protein, [Butylated Hydroxytoluene co-treated with Oxygen] results in increased expression of CTNNB1 protein

PMID:16272459
affects localizationISORGD:7337056480464CTDOxygen deficiency affects the localization of CTNNB1 protein

PMID:25297617
decreases acetylationISORGD:7337056480464CTDOxygen deficiency results in decreased acetylation of CTNNB1 protein

PMID:22245592
decreases expressionISORGD:7337056480464CTDOxygen deficiency results in decreased expression of CTNNB1 mRNA

PMID:17175027
multiple interactionsISORGD:7337056480464CTD[amurensin G results in decreased activity of SIRT1 protein] inhibits the reaction [Oxygen deficiency results in decreased expression of CTNNB1], resveratrol inhibits the reaction [Oxygen deficiency affects the localization of CTNNB1 protein], SIRT1 protein affects the reaction [Oxygen deficiency results in decreased expression of CTNNB1 protein]

PMID:22245592, PMID:25297617
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.