CTNNB1 (catenin beta 1) - Rat Genome Database

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Gene: CTNNB1 (catenin beta 1) Canis lupus familiaris
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Symbol: CTNNB1
Name: catenin beta 1
RGD ID: 12299678
Description: ENCODES a protein that exhibits alpha-catenin binding (ortholog); cadherin binding (ortholog); delta-catenin binding (ortholog); INVOLVED IN bicellular tight junction assembly; acinar cell differentiation (ortholog); adherens junction assembly (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; E-cadherin signaling pathway; ASSOCIATED WITH Aberrant Crypt Foci (ortholog); adenocarcinoma (ortholog); adenoma (ortholog); FOUND IN cell-cell junction; exocytic vesicle; plasma membrane
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-catenin; catenin beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12310,559,722 - 10,572,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2310,559,718 - 10,572,927 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2310,596,271 - 10,609,470 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02310,821,172 - 10,860,317 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2310,821,086 - 10,860,327 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12310,656,868 - 10,670,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02310,798,400 - 10,811,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02310,790,373 - 10,803,572 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Aberrant Crypt Foci  (ISO)
adenocarcinoma  (ISO)
adenoma  (ISO)
Adrenal Gland Neoplasms  (ISO)
adrenocortical carcinoma  (ISO)
Aggressive Fibromatosis  (ISO)
Alazami Syndrome  (ISO)
Alzheimer's disease  (ISO)
angiosarcoma  (ISO)
Animal Disease Models  (ISO)
atherosclerosis  (ISO)
autism spectrum disorder  (ISO)
autosomal dominant intellectual developmental disorder 19  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
calcinosis  (ISO)
Cecal Neoplasms  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
colon adenocarcinoma  (ISO)
colon carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congenital muscular dystrophy-dystroglycanopathy type A8  (ISO)
Craniofacial Abnormalities  (ISO)
craniopharyngioma  (ISO)
desmoid tumor  (ISO)
Developmental Disabilities  (ISO)
Developmental Disease  (ISO)
Diabetic Cardiomyopathies  (ISO)
dilated cardiomyopathy  (ISO)
disease  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
endodermal sinus tumor  (ISO)
Endometrial Intraepithelial Neoplasia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
esophageal carcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
exudative vitreoretinopathy  (ISO)
exudative vitreoretinopathy 1  (ISO)
exudative vitreoretinopathy 7  (ISO)
fibrolamellar carcinoma  (ISO)
Fibrosis  (ISO)
gallbladder cancer  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
granulosa cell tumor  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatitis B  (ISO)
hepatoblastoma  (ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
hereditary desmoid disease  (ISO)
hypertrophic cardiomyopathy  (ISO)
imperforate anus  (ISO)
in situ carcinoma  (ISO)
intellectual disability  (ISO)
Intestinal Neoplasms  (ISO)
invasive lobular carcinoma  (ISO)
Knee Osteoarthritis  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
Lung Neoplasms  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
malignant mesothelioma  (ISO)
Mandibular Neoplasms  (ISO)
mantle cell lymphoma  (ISO)
medulloblastoma  (ISO)
melanoma  (ISO)
Metaplasia  (ISO)
Multiple Abnormalities  (ISO)
muscular atrophy  (ISO)
Myocardial Ischemia  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephroblastoma  (ISO)
Nerve Degeneration  (ISO)
Nervous System Malformations  (ISO)
Neurodevelopmental Disorders  (ISO)
No-Reflow Phenomenon  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic adenocarcinoma  (ISO)
pancreatic cancer  (ISO)
Parathyroid Neoplasms  (ISO)
Peritoneal Neoplasms  (ISO)
Phyllodes Tumor  (ISO)
pilomatrixoma  (ISO)
polycystic liver disease  (ISO)
Polycystic Liver Disease 1  (ISO)
progressive osseous heteroplasia  (ISO)
prostate adenocarcinoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
Recurrence  (ISO)
renal cell carcinoma  (ISO)
Renal Cell Carcinoma 1  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
Stevens-Johnson syndrome  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
teratoma  (ISO)
thyroid gland papillary carcinoma  (ISO)
Thyroid Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Urinary Bladder Neoplasm  (ISO)
uterine cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
Uterine Neoplasms  (ISO)
Vascular Calcification  (ISO)
Ventricular Dysfunction, Left  (ISO)
Ventricular Remodeling  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acinar cell differentiation  (IEA,ISO)
adherens junction assembly  (IEA,ISS)
adherens junction organization  (IEA,ISO)
animal organ development  (IEA,ISO)
anterior/posterior axis specification  (IEA,ISO)
apoptotic signaling pathway  (IEA,ISO)
astrocyte-dopaminergic neuron signaling  (IEA)
bicellular tight junction assembly  (IDA)
bone remodeling  (ISO)
bone resorption  (IEA,ISO)
branching involved in blood vessel morphogenesis  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (IEA,ISO)
canonical Wnt signaling pathway  (IBA,IEA,ISO,ISS)
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation  (IEA)
cell adhesion  (IEA,ISS)
cell differentiation  (IEA,ISO)
cell fate specification  (IEA,ISO)
cell maturation  (IEA,ISO)
cell morphogenesis  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cell-cell adhesion  (IBA,IEA,ISO,ISS)
cell-matrix adhesion  (IEA,ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to growth factor stimulus  (IEA,ISS)
cellular response to indole-3-methanol  (IEA,ISS)
cellular response to insulin-like growth factor stimulus  (ISO)
cellular response to lithium ion  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to zinc ion starvation  (ISO)
central nervous system vasculogenesis  (IEA,ISO)
chemical synaptic transmission  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
cranial ganglion development  (IEA)
cranial skeletal system development  (IEA)
DNA-templated transcription  (IEA,ISO)
dorsal root ganglion development  (IEA)
dorsal/ventral axis specification  (IEA,ISO)
dorsal/ventral pattern formation  (IEA,ISO)
ectoderm development  (IEA,ISO)
embryonic axis specification  (IEA,ISO)
embryonic brain development  (IEA)
embryonic digit morphogenesis  (IEA,ISO)
embryonic foregut morphogenesis  (IEA,ISO)
embryonic forelimb morphogenesis  (IEA,ISO)
embryonic heart tube development  (IEA,ISO)
embryonic hindlimb morphogenesis  (IEA,ISO)
embryonic organ development  (IEA)
embryonic skeletal limb joint morphogenesis  (IEA)
endoderm formation  (IEA,ISO)
endodermal cell fate commitment  (IEA,ISO)
endothelial tube morphogenesis  (IEA,ISS)
epididymis development  (ISO)
epithelial cell differentiation involved in prostate gland development  (IEA,ISO)
epithelial cell proliferation involved in prostate gland development  (IEA,ISO)
epithelial tube branching involved in lung morphogenesis  (IEA,ISO)
establishment of blood-brain barrier  (IEA,ISO)
establishment of blood-retinal barrier  (IEA,ISO)
fibroblast growth factor receptor signaling pathway  (IEA,ISO)
forebrain development  (IEA,ISO)
fungiform papilla formation  (IEA,ISO)
gastrulation with mouth forming second  (IEA,ISO)
gene expression  (IEA,ISO)
genitalia morphogenesis  (IEA,ISO)
glandular epithelial cell differentiation  (IEA,ISO)
glial cell fate determination  (IEA,ISO)
hair cycle process  (IEA,ISO)
hair follicle morphogenesis  (IEA,ISO)
hair follicle placode formation  (IEA,ISO)
heart development  (IEA,ISO)
hemopoiesis  (IEA,ISO)
hindbrain development  (IEA)
hypothalamus development  (IEA)
in utero embryonic development  (IEA,ISO)
kidney development  (IEA,ISO)
layer formation in cerebral cortex  (IEA,ISO)
lens morphogenesis in camera-type eye  (IEA,ISO)
limb development  (IEA,ISO)
liver development  (ISO)
lung cell differentiation  (IEA,ISO)
lung development  (IEA,ISO)
lung epithelial cell differentiation  (IEA,ISO)
lung induction  (IEA,ISO)
lung-associated mesenchyme development  (IEA,ISO)
male genitalia development  (IEA,ISO)
MAPK cascade  (IEA,ISO)
mesenchymal cell proliferation  (IEA,ISO)
mesenchymal cell proliferation involved in lung development  (IEA,ISO)
mesenchymal stem cell differentiation  (IEA)
metanephros morphogenesis  (IEA,ISO)
midbrain development  (IEA)
midbrain dopaminergic neuron differentiation  (IEA)
midgut development  (ISO)
morphogenesis of embryonic epithelium  (IEA,ISO)
myoblast differentiation  (ISO)
myoblast proliferation  (IEA,ISO)
negative regulation of angiogenesis  (IEA)
negative regulation of apoptotic process  (IEA)
negative regulation of apoptotic signaling pathway  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (IEA)
negative regulation of cell differentiation  (IEA,ISO)
negative regulation of cell population proliferation  (IEA,ISS)
negative regulation of chondrocyte differentiation  (IEA,ISO)
negative regulation of DNA-templated transcription  (IEA,ISO,ISS)
negative regulation of gene expression  (IEA)
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis  (IEA,ISO)
negative regulation of mitotic cell cycle, embryonic  (IEA,ISS)
negative regulation of neurogenesis  (IEA)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of oligodendrocyte differentiation  (IEA,ISO)
negative regulation of osteoclast differentiation  (IEA,ISO)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (IEA)
negative regulation of protein sumoylation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
nephron tubule formation  (IEA,ISO)
nervous system development  (IEA)
neural plate development  (IEA,ISO)
neuroblast proliferation  (IEA,ISO)
neuron differentiation  (IEA)
neuron fate determination  (IEA,ISO)
neuron migration  (IEA,ISO)
neuron projection extension  (IEA,ISS)
odontogenesis of dentin-containing tooth  (IEA,ISO)
oligodendrocyte differentiation  (IEA,ISO)
oocyte development  (IEA,ISO)
osteoblast differentiation  (IEA,ISO)
osteoclast differentiation  (IEA,ISO)
outflow tract morphogenesis  (IEA)
oviduct development  (IEA,ISO)
pancreas development  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISS)
positive regulation of branching involved in lung morphogenesis  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of determination of dorsal identity  (IEA,ISO)
positive regulation of DNA-templated transcription  (IEA,ISO,ISS)
positive regulation of endothelial cell differentiation  (IEA,ISO)
positive regulation of epithelial cell differentiation  (IEA,ISO)
positive regulation of epithelial cell proliferation involved in prostate gland development  (IEA,ISO)
positive regulation of epithelial to mesenchymal transition  (IEA,ISO)
positive regulation of fibroblast growth factor receptor signaling pathway  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of heparan sulfate proteoglycan biosynthetic process  (IEA,ISS)
positive regulation of MAPK cascade  (IEA,ISO)
positive regulation of mesenchymal cell proliferation  (IEA,ISO)
positive regulation of myoblast proliferation  (IEA,ISO)
positive regulation of neural precursor cell proliferation  (IEA)
positive regulation of neuroblast proliferation  (IEA,ISO,ISS)
positive regulation of neuron apoptotic process  (IEA)
positive regulation of odontoblast differentiation  (IEA)
positive regulation of osteoblast differentiation  (IEA,ISO)
positive regulation of skeletal muscle tissue development  (IEA)
positive regulation of stem cell proliferation  (IEA,ISO)
positive regulation of telomere maintenance via telomerase  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IEA,ISO,ISS)
positive regulation of transcription elongation by RNA polymerase II  (IEA)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IEA)
protein localization  (IEA,ISO)
protein localization to cell surface  (IEA,ISS)
protein polyubiquitination  (IEA)
proximal/distal pattern formation  (IEA,ISO)
regulation of apoptotic process  (IEA,ISO)
regulation of calcium ion import  (IEA,ISS)
regulation of cell differentiation  (IEA,ISO)
regulation of cell population proliferation  (IEA,ISO)
regulation of centriole-centriole cohesion  (IEA,ISS)
regulation of centromeric sister chromatid cohesion  (IEA,ISS)
regulation of epithelial cell differentiation  (IEA,ISO)
regulation of gene expression  (IEA,ISO)
regulation of myelination  (IEA,ISO)
regulation of nephron tubule epithelial cell differentiation  (IEA)
regulation of osteoblast differentiation  (IEA,ISO)
regulation of osteoclast differentiation  (IEA,ISO)
regulation of protein localization to cell surface  (IEA,ISS)
regulation of protein ubiquitination  (IEA)
regulation of secondary heart field cardioblast proliferation  (IEA,ISO)
regulation of smooth muscle cell proliferation  (IEA,ISS)
regulation of synapse assembly  (IEA)
regulation of T cell proliferation  (IEA,ISO)
regulation of timing of anagen  (IEA)
regulation of transcription by RNA polymerase II  (IEA,ISO)
renal inner medulla development  (IEA,ISO)
renal outer medulla development  (IEA,ISO)
renal vesicle formation  (IEA,ISO)
response to activity  (ISO)
response to cadmium ion  (ISO)
response to cytokine  (ISO)
response to estradiol  (IEA,ISO,ISS)
response to estrogen  (ISO)
response to hormone  (ISO)
response to organic cyclic compound  (ISO)
response to xenobiotic stimulus  (IEA)
Schwann cell proliferation  (ISO)
skeletal system development  (IEA,ISO)
skin development  (IEA,ISO)
smooth muscle cell differentiation  (IEA,ISO)
stem cell proliferation  (IEA,ISO)
sympathetic ganglion development  (IEA,ISS)
synapse organization  (IEA,ISO)
synaptic vesicle clustering  (IEA)
synaptic vesicle transport  (IEA,ISO)
T cell differentiation  (IEA,ISO)
T cell differentiation in thymus  (IEA,ISO)
thymus development  (IEA,ISO)
tissue homeostasis  (IEA,ISO)
trachea formation  (IEA,ISO)
trachea morphogenesis  (IEA,ISO)
transcription by RNA polymerase II  (IEA,ISO)
vasculature development  (IEA,ISO)
vasculogenesis  (IEA,ISO)
Wnt signaling pathway  (IEA)

Cellular Component
adherens junction  (IBA,IEA,ISO,ISS)
anchoring junction  (IEA)
apical junction complex  (IEA)
apical part of cell  (IEA)
apical plasma membrane  (ISO)
apicolateral plasma membrane  (IEA)
basolateral plasma membrane  (IEA)
beta-catenin destruction complex  (IEA,ISS)
beta-catenin-ICAT complex  (IEA,ISO)
beta-catenin-TCF complex  (IEA,ISO)
beta-catenin-TCF7L2 complex  (IEA,ISS)
bicellular tight junction  (IEA)
catenin complex  (IBA,IEA,ISS)
cell cortex  (IEA,ISS)
cell junction  (IEA,ISS)
cell periphery  (IEA,ISS)
cell projection  (IEA)
cell projection membrane  (IEA)
cell-cell junction  (IDA,IEA,ISS)
centrosome  (IEA,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
cytoskeleton  (IEA)
cytosol  (IEA,ISS)
dendritic shaft  (ISO)
euchromatin  (IEA)
exocytic vesicle  (IDA)
fascia adherens  (IEA)
flotillin complex  (IEA)
glutamatergic synapse  (IEA,ISO)
intercalated disc  (IEA,ISO)
intracellular membrane-bounded organelle  (IEA)
lamellipodium  (IEA)
lateral plasma membrane  (IEA,ISO)
membrane  (IEA)
microvillus membrane  (IEA)
nuclear membrane  (ISO)
nucleus  (IBA,IEA,ISO,ISS)
perinuclear region of cytoplasm  (IEA,ISO,ISS)
plasma membrane  (IDA,IEA)
postsynaptic density, intracellular component  (IEA,ISO)
postsynaptic membrane  (IEA,ISO)
presynaptic active zone cytoplasmic component  (IEA,ISO)
presynaptic membrane  (IEA,ISO)
protein-containing complex  (IEA,ISO)
protein-DNA complex  (IEA,ISS)
RNA polymerase II transcription regulator complex  (IEA,ISO)
Schaffer collateral - CA1 synapse  (IEA,ISO)
Scrib-APC-beta-catenin complex  (IEA)
spindle pole  (IEA)
synapse  (IEA,ISS)
tight junction  (ISO)
transcription regulator complex  (IEA,ISS)
Wnt signalosome  (IEA)
Z disc  (IEA)

References
Additional References at PubMed
PMID:8636221   PMID:10873669   PMID:16341006   PMID:16621792   PMID:18019408   PMID:18504258   PMID:18772141   PMID:18949487   PMID:20974860   PMID:21152425   PMID:21303455   PMID:21388636  
PMID:21909376   PMID:22022527   PMID:22301074   PMID:24256430   PMID:24529514   PMID:26023140   PMID:26103686   PMID:27155731   PMID:27782880   PMID:29311227   PMID:30032202   PMID:33044004  
PMID:37756605  


Genomics

Comparative Map Data
CTNNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12310,559,722 - 10,572,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2310,559,718 - 10,572,927 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2310,596,271 - 10,609,470 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02310,821,172 - 10,860,317 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2310,821,086 - 10,860,327 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12310,656,868 - 10,670,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02310,798,400 - 10,811,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02310,790,373 - 10,803,572 (+)NCBIUU_Cfam_GSD_1.0
CTNNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38341,199,505 - 41,240,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl341,194,741 - 41,260,096 (+)EnsemblGRCh38hg38GRCh38
GRCh37341,240,996 - 41,281,934 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36341,215,946 - 41,256,943 (+)NCBINCBI36Build 36hg18NCBI36
Build 34341,216,015 - 41,256,938NCBI
Celera341,179,363 - 41,220,269 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef341,285,983 - 41,326,988 (+)NCBIHuRef
CHM1_1341,191,513 - 41,232,505 (+)NCBICHM1_1
T2T-CHM13v2.0341,214,904 - 41,255,840 (+)NCBIT2T-CHM13v2.0
Ctnnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,762,466 - 120,789,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9120,758,282 - 120,789,573 (+)EnsemblGRCm39 Ensembl
GRCm389120,933,400 - 120,960,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,929,216 - 120,960,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,842,518 - 120,869,625 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369120,782,173 - 120,809,205 (+)NCBIMGSCv36mm8
Celera9121,404,098 - 121,431,499 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.19NCBI
Ctnnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88129,517,576 - 129,544,661 (+)NCBIGRCr8
mRatBN7.28120,640,008 - 120,667,110 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8120,639,995 - 120,667,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8126,248,801 - 126,258,310 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08124,447,834 - 124,457,343 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,278,384 - 122,287,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08129,601,511 - 129,628,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8129,617,812 - 129,627,372 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,798,888 - 128,825,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,978,161 - 125,987,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18125,997,897 - 126,007,407 (+)NCBI
Celera8119,795,816 - 119,805,325 (+)NCBICelera
Cytogenetic Map8q32NCBI
Ctnnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,030,716 - 29,047,449 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542029,030,716 - 29,047,447 (-)NCBIChiLan1.0ChiLan1.0
CTNNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2241,160,670 - 41,201,708 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1341,165,431 - 41,206,468 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0341,104,940 - 41,145,934 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1341,372,368 - 41,414,030 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl341,373,726 - 41,414,030 (+)Ensemblpanpan1.1panPan2
Ctnnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118196,856,510 - 196,896,035 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647329,999,562 - 30,038,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647329,999,542 - 30,034,610 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,164,277 - 25,208,311 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,163,550 - 25,208,314 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21327,623,189 - 27,667,260 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CTNNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,679,488 - 2,725,034 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl222,684,022 - 2,723,949 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041164,464,011 - 164,505,060 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473077,875,257 - 77,887,234 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473077,876,361 - 77,887,228 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CTNNB1
85 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000008400   ⟹   ENSCAFP00000007783
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2310,559,728 - 10,572,927 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000059813   ⟹   ENSCAFP00000060268
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2310,559,718 - 10,570,129 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031295   ⟹   ENSCAFP00845024497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2310,821,086 - 10,860,312 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031427   ⟹   ENSCAFP00845024610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2310,821,086 - 10,860,312 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031553   ⟹   ENSCAFP00845024702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2310,821,093 - 10,860,327 (+)Ensembl
RefSeq Acc Id: NM_001137652   ⟹   NP_001131124
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12310,559,728 - 10,572,927 (+)NCBI
Dog10K_Boxer_Tasha2310,596,271 - 10,609,470 (+)NCBI
ROS_Cfam_1.02310,847,113 - 10,860,311 (+)NCBI
UMICH_Zoey_3.12310,656,868 - 10,670,063 (+)NCBI
UNSW_CanFamBas_1.02310,798,400 - 10,811,602 (+)NCBI
UU_Cfam_GSD_1.02310,790,373 - 10,803,572 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038431596   ⟹   XP_038287524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02310,821,172 - 10,860,317 (+)NCBI
RefSeq Acc Id: XM_038431597   ⟹   XP_038287525
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02310,821,172 - 10,860,317 (+)NCBI
RefSeq Acc Id: XM_038431598   ⟹   XP_038287526
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02310,821,172 - 10,860,317 (+)NCBI
RefSeq Acc Id: XM_038431599   ⟹   XP_038287527
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02310,847,275 - 10,860,317 (+)NCBI
RefSeq Acc Id: NP_001131124   ⟸   NM_001137652
- UniProtKB: B6V8E6 (UniProtKB/Swiss-Prot),   A0A8C0LI45 (UniProtKB/TrEMBL),   A0A8C0TDS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000060268   ⟸   ENSCAFT00000059813
RefSeq Acc Id: ENSCAFP00000007783   ⟸   ENSCAFT00000008400
RefSeq Acc Id: XP_038287524   ⟸   XM_038431596
- Peptide Label: isoform X1
- UniProtKB: B6V8E6 (UniProtKB/Swiss-Prot),   A0A8C0LI45 (UniProtKB/TrEMBL),   A0A8C0TDS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038287525   ⟸   XM_038431597
- Peptide Label: isoform X1
- UniProtKB: B6V8E6 (UniProtKB/Swiss-Prot),   A0A8C0LI45 (UniProtKB/TrEMBL),   A0A8C0TDS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038287526   ⟸   XM_038431598
- Peptide Label: isoform X1
- UniProtKB: B6V8E6 (UniProtKB/Swiss-Prot),   A0A8C0LI45 (UniProtKB/TrEMBL),   A0A8C0TDS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038287527   ⟸   XM_038431599
- Peptide Label: isoform X2
- UniProtKB: A0A8I3P3V9 (UniProtKB/TrEMBL),   A0A8P0PHX3 (UniProtKB/TrEMBL),   A0A8C0TDS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845024610   ⟸   ENSCAFT00845031427
RefSeq Acc Id: ENSCAFP00845024497   ⟸   ENSCAFT00845031295
RefSeq Acc Id: ENSCAFP00845024702   ⟸   ENSCAFT00845031553


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005204 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040020498 UniProtKB/TrEMBL
  ENSCAFG00845017609 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008400.5 UniProtKB/TrEMBL
  ENSCAFT00000059813.2 UniProtKB/TrEMBL
  ENSCAFT00000102748.1 UniProtKB/TrEMBL
  ENSCAFT00040038044.1 UniProtKB/TrEMBL
  ENSCAFT00845031295 ENTREZGENE
  ENSCAFT00845031295.1 UniProtKB/TrEMBL
  ENSCAFT00845031427.1 UniProtKB/TrEMBL
  ENSCAFT00845031553 ENTREZGENE
  ENSCAFT00845031553.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Armadillo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Beta-catenin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:477032 UniProtKB/Swiss-Prot
NCBI Gene CTNNB1 ENTREZGENE
PANTHER CATENIN BETA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45976 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS BCATNINFAMLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARM_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ARM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0LI45 ENTREZGENE
  A0A8C0TDS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NUM7_CANLF UniProtKB/TrEMBL
  A0A8I3P3V9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S2U2_CANLF UniProtKB/TrEMBL
  A0A8P0PHX3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SAR1_CANLF UniProtKB/TrEMBL
  A0A8P0TC56_CANLF UniProtKB/TrEMBL
  B6V8E6 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:39700 ENTREZGENE