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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:10043
Term: wogonin
Definition: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.
Chemical ID: MESH:C085514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:704876480464CTDwogonin results in decreased expression of CTNNB1 protein

PMID:23872260
decreases expressionISORGD:7337056480464CTDwogonin results in decreased expression of CTNNB1 protein

PMID:23872260
increases expressionISORGD:704876480464CTDwogonin results in increased expression of CTNNB1 protein modified form

PMID:23872260
increases expressionISORGD:7337056480464CTDwogonin results in increased expression of CTNNB1 protein modified form

PMID:23872260
multiple interactionsISORGD:704876480464CTDLithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein], wogonin inhibits the reaction [Cisplatin results in increased expression of CTNNB1 protein]

PMID:23872260, PMID:31103702
multiple interactionsISORGD:7337056480464CTDLithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]

PMID:23872260
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.