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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:78761
Term: ML-7
Definition: An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).
Chemical ID: MESH:C070571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects localizationISORGD:7337056480464CTDML 7 affects the localization of CTNNB1 protein

PMID:18710790
decreases expressionISORGD:7337056480464CTDML 7 results in decreased expression of CTNNB1 protein

PMID:18710790
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.