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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:10136
Term: gingerol
Definition: A beta-hydroxy ketone that is 5-hydroxydecan-3-one substituted by a 4-hydroxy-3-methoxyphenyl moiety at position 1; believed to inhibit adipogenesis. It is a constituent of fresh ginger.
Chemical ID: MESH:C007845
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDgingerol results in increased expression of CTNNB1 mRNA

PMID:26498061
multiple interactionsEXP 6480464CTDgingerol results in increased expression of and affects the localization of CTNNB1 protein

PMID:26498061
affects localizationISORGD:7337056480464CTDgingerol affects the localization of CTNNB1 protein

PMID:18058799
multiple interactionsISORGD:7337056480464CTDgingerol promotes the reaction [IL1B protein results in increased expression of CTNNB1 protein]

PMID:27645308
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.