GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ctnnb1 | affects response to substance | EXP | | 6480464 | CTD | CTNNB1 protein affects the susceptibility to Phenobarbital | PMID:21705713 | Ctnnb1 | increases expression | EXP | | 6480464 | CTD | Phenobarbital results in increased expression of CTNNB1 protein alternative form | PMID:31836555 | Ctnnb1 | increases mutagenesis | EXP | | 6480464 | CTD | Phenobarbital results in increased mutagenesis of CTNNB1 exon; Phenobarbital results in increased mutagenesis of CTNNB1 gene; Phenobarbital results in increased mutagenesis of CTNNB1 protein | PMID:11753661 PMID:12384525 PMID:31836555 | Ctnnb1 | multiple interactions | EXP | | 6480464 | CTD | [Diethylnitrosamine co-treated with Phenobarbital] results in increased mutagenesis of CTNNB1 gene; [Phenobarbital co-treated with CTNNB1 protein mutant form] results in increased expression of GSTM2 mRNA; [Phenobarbital co-treated with CTNNB1 protein mutant form] results in increased expression of GSTM3 mRNA; [Phenobarbital co-treated with CTNNB1 protein mutant form] results in increased expression of GSTM6 mRNA; [Phenobarbital co-treated with CTNNB1 protein mutant form] results in increased expression of NR1I3 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased mutagenesis of CTNNB1 gene; [Phenobarbital results in increased mutagenesis of CTNNB1 gene] which results in increased expression of GLUL mRNA; [Phenobarbital results in increased mutagenesis of CTNNB1 gene] which results in increased expression of GLUL protein; CTNNB1 protein affects the reaction [Phenobarbital results in increased expression of MEG3 mRNA]; CTNNB1 protein affects the reaction [Phenobarbital results in increased expression of RIAN mRNA]; Phenobarbital affects the reaction [Cycloheximide results in decreased expression of CTNNB1 protein]; Phenobarbital inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CTNNB1 protein] | PMID:12384525 PMID:20118494 PMID:21047994 PMID:23091169 PMID:24535843 PMID:27693619 | |
Go Back to source page | Continue to Ontology report |