Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases degradationISORGD:704876480464CTD2, 4, 5, 2', 4', 5'-hexachlorobiphenyl results in increased degradation of CTNNB1 protein

PMID:19464575
multiple interactionsISORGD:704876480464CTD2, 4, 5, 2', 4', 5'-hexachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of CTNNB1 protein, leupeptin inhibits the reaction [2, 4, 5, 2', 4', 5'-hexachlorobiphenyl results in increased degradation of CTNNB1 protein]

PMID:19464575
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.