Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550466
Species: Mus musculus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7337056480464CTDBerberine results in increased expression of CTNNB1 protein

PMID:26478571
multiple interactionsISORGD:7337056480464CTDCTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of BGLAP protein], CTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of RUNX2 mRNA], CTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of SPP1 protein], DKK1 protein inhibits the reaction [Berberine results in increased expression of CTNNB1 protein]

PMID:26478571
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.