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Gene: Ak1 (adenylate kinase 1) Mus musculus
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Symbol: Ak1
Name: adenylate kinase 1
Description: Exhibits adenylate kinase activity. Predicted to contribute to phosphotransferase activity, phosphate group as acceptor. Involved in cell cycle arrest. Localizes to cytoplasm; outer dense fiber; and plasma membrane. Is expressed in several structures, including alimentary system; heart; musculature; nervous system; and nose. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and hemolytic anemia. Orthologous to human AK1 (adenylate kinase 1); PARTICIPATES IN adefovir pharmacokinetics pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate kinase isoenzyme 1; adenylate monophosphate kinase; AK 1; Ak-1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; B430205N08Rik; cytosolic adenylate kinase; myokinase
Orthologs:
Homo sapiens (human) : AK1 (adenylate kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ak1 (adenylate kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak1 (adenylate kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AK1 (adenylate kinase 1)
Canis lupus familiaris (dog) : AK1 (adenylate kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak1 (adenylate kinase 1)
Sus scrofa (pig) : AK1 (adenylate kinase 1)
Chlorocebus sabaeus (African green monkey) : AK1 (adenylate kinase 1)
Heterocephalus glaber (naked mole-rat) : Ak1 (adenylate kinase 1)
more info ...
Related Pseudogenes: Gm6092  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl232,621,758 - 32,635,058 (+)EnsemblGRCm38mm10GRCm38
GRCm38232,621,758 - 32,635,058 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,485,024 - 32,490,572 (+)NCBIGRCm37mm9NCBIm37
MGSCv36232,451,513 - 32,457,061 (+)NCBImm8
Celera232,336,146 - 32,341,694 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10129
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.