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Gene: Ak1 (adenylate kinase 1) Mus musculus
Symbol: Ak1
Name: adenylate kinase 1
Description: Exhibits adenylate kinase activity. Predicted to contribute to phosphotransferase activity, phosphate group as acceptor. Involved in cell cycle arrest. Localizes to cytoplasm; outer dense fiber; and plasma membrane. Is expressed in several structures, including alimentary system; heart; musculature; nervous system; and nose. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and hemolytic anemia. Orthologous to human AK1 (adenylate kinase 1); PARTICIPATES IN adefovir pharmacokinetics pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate kinase isoenzyme 1; adenylate monophosphate kinase; AK 1; Ak-1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; B430205N08Rik; cytosolic adenylate kinase; myokinase
Homo sapiens (human) : AK1 (adenylate kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ak1 (adenylate kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak1 (adenylate kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AK1 (adenylate kinase 1)
Canis lupus familiaris (dog) : AK1 (adenylate kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak1 (adenylate kinase 1)
Sus scrofa (pig) : AK1 (adenylate kinase 1)
Chlorocebus sabaeus (African green monkey) : AK1 (adenylate kinase 1)
Heterocephalus glaber (naked mole-rat) : Ak1 (adenylate kinase 1)
more info ...
Related Pseudogenes: Gm6092  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl232,621,758 - 32,635,058 (+)EnsemblGRCm38mm10GRCm38
GRCm38232,621,758 - 32,635,058 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,485,024 - 32,490,572 (+)NCBIGRCm37mm9NCBIm37
MGSCv36232,451,513 - 32,457,061 (+)NCBImm8
Celera232,336,146 - 32,341,694 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ak1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10129
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.