Gnrh1 (gonadotropin releasing hormone 1) - Rat Genome Database

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Gene: Gnrh1 (gonadotropin releasing hormone 1) Mus musculus
Analyze
Symbol: Gnrh1
Name: gonadotropin releasing hormone 1
RGD ID: 1553302
MGI Page MGI
Description: Predicted to enable gonadotropin hormone-releasing hormone activity and gonadotropin-releasing hormone receptor binding activity. Acts upstream of or within several processes, including negative regulation of neuron migration; regulation of ovarian follicle development; and response to ethanol. Located in extracellular space. Is expressed in several structures, including alimentary system; nervous system; olfactory system; and testis. Used to study hypogonadotropic hypogonadism 12 with or without anosmia. Human ortholog(s) of this gene implicated in breast cancer; hypogonadotropic hypogonadism 12 with or without anosmia; and periodontitis. Orthologous to human GNRH1 (gonadotropin releasing hormone 1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Gnrh; Gnrh2; gonadotropin releasing hormone 2; hpg; hypogonadal; L; LH; LHRH; Lhrh1; Lnrh; luteinizing hormone-releasing hormone I; progonadoliberin I; progonadoliberin-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391467,982,717 - 67,986,889 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1467,982,630 - 67,986,888 (+)EnsemblGRCm39 Ensembl
GRCm381467,745,181 - 67,749,440 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1467,745,181 - 67,749,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371468,363,286 - 68,367,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361466,699,676 - 66,702,621 (+)NCBIMGSCv36mm8
Celera1465,502,860 - 65,507,056 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',4,5-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
alfuzosin  (ISO)
allethrin  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (EXP)
bicuculline  (ISO)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (EXP)
calcium dichloride  (ISO)
carvone  (ISO)
chlormequat chloride  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clomiphene  (ISO)
cocaine  (EXP)
cyhalothrin  (ISO)
cypermethrin  (EXP,ISO)
DDE  (EXP,ISO)
DDT  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dopamine  (ISO)
emamectin benzoate  (ISO)
Estradiol 17beta-cyclopentylpropionate  (ISO)
fenvalerate  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
fulvestrant  (EXP)
gamma-aminobutyric acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (ISO)
ketoconazole  (ISO)
KT 5823  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melatonin  (ISO)
melittin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methoxychlor  (EXP,ISO)
methylene blue  (ISO)
methylmercury chloride  (ISO)
muscimol  (ISO)
ochratoxin A  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
Phenoxybenzamine  (ISO)
phenylephrine  (ISO)
potassium chloride  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
procymidone  (ISO)
progesterone  (ISO)
propofol  (ISO)
pyrethrins  (ISO)
raloxifene  (ISO)
sevoflurane  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
Tetrachlorobisphenol A  (EXP,ISO)
tetrodotoxin  (EXP)
thioacetamide  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
wortmannin  (EXP)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anogenital distance  (IAGP)
abnormal circulating protein level  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal female reproductive system physiology  (IAGP)
abnormal gametogenesis  (IAGP)
abnormal hormone level  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal ovary physiology  (IAGP)
abnormal pituitary gland physiology  (IAGP)
abnormal scrotum morphology  (IAGP)
abnormal sex gland morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal vagina orifice morphology  (IAGP)
absent Leydig cells  (IAGP)
absent seminal vesicle  (IAGP)
arrest of male meiosis  (IAGP)
cryptorchism  (IAGP)
decreased adrenocorticotropin level  (IAGP)
decreased body weight  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased follicle stimulating hormone level  (IAGP)
decreased kidney weight  (IAGP)
decreased liver weight  (IAGP)
decreased luteinizing hormone level  (IAGP)
decreased prolactin level  (IAGP)
decreased tumor incidence  (IAGP)
delayed female fertility  (IAGP)
delayed vaginal opening  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
increased B cell number  (IAGP)
increased bone marrow cell number  (IAGP)
increased circulating estradiol level  (IAGP)
increased circulating luteinizing hormone level  (IAGP)
increased circulating progesterone level  (IAGP)
increased immature B cell number  (IAGP)
increased mature B cell number  (IAGP)
no abnormal phenotype detected  (IAGP)
obese  (IAGP)
short diestrus  (IAGP)
short estrous cycle  (IAGP)
short metestrus  (IAGP)
short proestrus  (IAGP)
small ovary  (IAGP)
small penis  (IAGP)
small salivary gland  (IAGP)
small seminal vesicle  (IAGP)
small testis  (IAGP)
small uterus  (IAGP)
thin skin  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation. Bouligand J, etal., N Engl J Med. 2009 Jun 25;360(26):2742-8. doi: 10.1056/NEJMoa0900136. Epub 2009 Jun 17.
2. GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism. Chan YM, etal., Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11703-8. doi: 10.1073/pnas.0903449106. Epub 2009 Jun 30.
3. R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism. Maione L, etal., PLoS One. 2013 Jul 25;8(7):e69616. doi: 10.1371/journal.pone.0069616. Print 2013.
4. The hypogonadal mouse: reproductive functions restored by gene therapy. Mason AJ, etal., Science. 1986 Dec 12;234(4782):1372-8.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients. Piersma D, etal., Breast Cancer Res. 2007;9(4):R51.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Combining growth hormone-releasing hormone antagonist with luteinizing hormone-releasing hormone antagonist greatly augments benign prostatic hyperplasia shrinkage. Rick FG, etal., J Urol. 2012 Apr;187(4):1498-504. doi: 10.1016/j.juro.2011.11.081. Epub 2012 Feb 17.
14. Large-scale investigation of genomic markers for severe periodontitis. Suzuki A, etal., Odontology. 2004 Sep;92(1):43-7.
Additional References at PubMed
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Genomics

Comparative Map Data
Gnrh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391467,982,717 - 67,986,889 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1467,982,630 - 67,986,888 (+)EnsemblGRCm39 Ensembl
GRCm381467,745,181 - 67,749,440 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1467,745,181 - 67,749,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371468,363,286 - 68,367,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361466,699,676 - 66,702,621 (+)NCBIMGSCv36mm8
Celera1465,502,860 - 65,507,056 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.66NCBI
GNRH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38825,419,258 - 25,425,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl825,419,258 - 25,424,654 (-)EnsemblGRCh38hg38GRCh38
GRCh37825,276,774 - 25,282,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36825,332,691 - 25,338,473 (-)NCBINCBI36Build 36hg18NCBI36
Build 34825,332,692 - 25,337,836NCBI
Celera824,237,655 - 24,243,437 (-)NCBICelera
Cytogenetic Map8p21.2NCBI
HuRef823,821,751 - 23,827,534 (-)NCBIHuRef
CHM1_1825,478,220 - 25,484,032 (-)NCBICHM1_1
T2T-CHM13v2.0825,694,484 - 25,700,266 (-)NCBIT2T-CHM13v2.0
Gnrh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81546,147,878 - 46,152,086 (+)NCBIGRCr8
mRatBN7.21541,972,482 - 41,976,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1541,942,339 - 41,976,690 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1541,972,905 - 41,973,581 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1543,837,145 - 43,841,353 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01544,987,366 - 44,991,574 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01543,432,699 - 43,436,907 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01544,441,856 - 44,446,064 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1544,441,856 - 44,446,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1544,442,555 - 44,442,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01547,151,131 - 47,155,339 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41547,303,309 - 47,307,517 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11547,319,088 - 47,323,286 (+)NCBI
Celera1541,636,731 - 41,640,939 (+)NCBICelera
Cytogenetic Map15p12NCBI
Gnrh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540348,343,597 - 48,346,595 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540348,341,731 - 48,346,595 (-)NCBIChiLan1.0ChiLan1.0
GNRH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2743,960,415 - 43,967,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1819,674,806 - 19,680,584 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0824,700,268 - 24,707,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1821,609,407 - 21,616,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl821,609,407 - 21,615,936 (-)Ensemblpanpan1.1panPan2
GNRH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12532,038,631 - 32,043,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2532,039,613 - 32,043,028 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2532,623,319 - 32,627,816 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02532,237,978 - 32,242,489 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2532,238,905 - 32,242,478 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12532,193,651 - 32,198,162 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02532,043,144 - 32,047,652 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02532,208,954 - 32,213,456 (+)NCBIUU_Cfam_GSD_1.0
Gnrh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494310,029,435 - 10,033,174 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367571,282,185 - 1,285,832 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367571,282,185 - 1,285,804 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNRH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl149,442,971 - 9,453,035 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1149,442,971 - 9,447,521 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21410,597,132 - 10,607,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNRH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1823,543,717 - 23,550,728 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl823,542,806 - 23,547,771 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605218,616,776 - 18,623,795 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnrh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475820,447,583 - 20,450,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475820,447,413 - 20,451,059 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gnrh1
164 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:87
Interacting mature miRNAs:88
Transcripts:ENSMUST00000111095
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
10043888Cia51_mcollagen induced arthritis QTL 51 (mouse)Not determined146610389368785736Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse

Markers in Region
D14Mit28  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381467,749,485 - 67,749,690UniSTSGRCm38
MGSCv371468,367,542 - 68,367,747UniSTSGRCm37
Celera1465,507,105 - 65,507,296UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.4UniSTS
Whitehead Genetic1437.2UniSTS
Whitehead_YAC14 UniSTS
Gnrh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14D1UniSTS
cM Map1439.5UniSTS
Gnrh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381467,749,436 - 67,749,657UniSTSGRCm38
MGSCv371468,367,493 - 68,367,714UniSTSGRCm37
Celera1465,507,056 - 65,507,263UniSTS
Cytogenetic Map14D1UniSTS
cM Map1439.5UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000111095   ⟹   ENSMUSP00000106724
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,982,717 - 67,986,888 (+)Ensembl
GRCm38.p6 Ensembl1467,745,268 - 67,749,439 (+)Ensembl
Ensembl Acc Id: ENSMUST00000223929   ⟹   ENSMUSP00000153349
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,982,630 - 67,986,885 (+)Ensembl
GRCm38.p6 Ensembl1467,745,181 - 67,749,436 (+)Ensembl
Ensembl Acc Id: ENSMUST00000223951   ⟹   ENSMUSP00000153071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,983,719 - 67,986,802 (+)Ensembl
GRCm38.p6 Ensembl1467,746,270 - 67,749,353 (+)Ensembl
RefSeq Acc Id: NM_001416514   ⟹   NP_001403443
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391467,982,717 - 67,986,889 (+)NCBI
RefSeq Acc Id: NM_008145   ⟹   NP_032171
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391467,982,717 - 67,986,889 (+)NCBI
GRCm381467,745,181 - 67,749,436 (+)NCBI
MGSCv371468,363,286 - 68,367,493 (+)RGD
Celera1465,502,860 - 65,507,056 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032171   ⟸   NM_008145
- Peptide Label: isoform 1 preproprotein
- UniProtKB: P13562 (UniProtKB/Swiss-Prot),   Q3UTE9 (UniProtKB/TrEMBL),   Q14AC4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000106724   ⟸   ENSMUST00000111095
Ensembl Acc Id: ENSMUSP00000153349   ⟸   ENSMUST00000223929
Ensembl Acc Id: ENSMUSP00000153071   ⟸   ENSMUST00000223951
RefSeq Acc Id: NP_001403443   ⟸   NM_001416514
- Peptide Label: isoform 2
- UniProtKB: A0A286YDB0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P13562-F1-model_v2 AlphaFold P13562 1-90 view protein structure

Promoters
RGD ID:8682826
Promoter ID:EPDNEW_M19444
Type:single initiation site
Name:Gnrh1_1
Description:Mus musculus gonadotropin releasing hormone 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381467,745,268 - 67,745,328EPDNEW
RGD ID:6825045
Promoter ID:MM_KWN:17315
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   MEF_B6
Transcripts:NM_008145
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361468,362,606 - 68,363,106 (+)MPROMDB
RGD ID:6825044
Promoter ID:MM_KWN:17316
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   Kidney,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000111095
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361468,363,436 - 68,364,802 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95789 AgrOrtholog
Ensembl Genes ENSMUSG00000015812 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000111095 ENTREZGENE
  ENSMUST00000111095.4 UniProtKB/Swiss-Prot
  ENSMUST00000223929 ENTREZGENE
  ENSMUST00000223929.2 UniProtKB/TrEMBL
  ENSMUST00000223951.2 UniProtKB/Swiss-Prot
InterPro GnRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadoliberin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadoliberin_I_precursor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14714 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95789 ENTREZGENE
NCBI Gene 14714 ENTREZGENE
PANTHER PROGONADOLIBERIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10522 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GnRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gnrh1 PhenoGen
PRINTS GONADOLIBRNI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GNRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YDB0 ENTREZGENE, UniProtKB/TrEMBL
  GON1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q14AC4 ENTREZGENE, UniProtKB/TrEMBL
  Q3UTE9 ENTREZGENE, UniProtKB/TrEMBL