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Gene: GNRH1 (gonadotropin releasing hormone 1) Homo sapiens
Symbol: GNRH1
Name: gonadotropin releasing hormone 1
Description: Predicted to have gonadotropin hormone-releasing hormone activity and gonadotropin-releasing hormone receptor binding activity. Predicted to be involved in reproduction. Predicted to localize to the extracellular space. Implicated in breast cancer; hypogonadotropic hypogonadism 12 with or without anosmia; and periodontitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GNRH; GnRH-associated peptide 1; gonadotropin-releasing hormone 1; gonadotropin-releasing hormone 1 (leutinizing-releasing hormone); gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); GRH; HH12; leuteinizing-releasing hormone; LHRH; LNRH; luliberin I; progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor
Mus musculus (house mouse) : Gnrh1 (gonadotropin releasing hormone 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnrh1 (gonadotropin releasing hormone 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnrh1 (gonadotropin releasing hormone 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNRH1 (gonadotropin releasing hormone 1)
Canis lupus familiaris (dog) : GNRH1 (gonadotropin releasing hormone 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnrh1 (gonadotropin releasing hormone 1)
Sus scrofa (pig) : GNRH1 (gonadotropin releasing hormone 1)
Chlorocebus sabaeus (green monkey) : GNRH1 (gonadotropin releasing hormone 1)
Heterocephalus glaber (naked mole-rat) : Gnrh1 (gonadotropin releasing hormone 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl825,419,258 - 25,424,654 (-)Ensembl
GRCh38825,419,258 - 25,425,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37825,276,774 - 25,282,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36825,332,691 - 25,338,473 (-)NCBINCBI36hg18NCBI36
Build 34825,332,692 - 25,337,836NCBI
Celera824,237,655 - 24,243,437 (-)NCBI
Cytogenetic Map8p21.2NCBI
HuRef823,821,751 - 23,827,534 (-)NCBIHuRef
CHM1_1825,478,220 - 25,484,032 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GNRH1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69083
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.