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Gene: Lta4h (leukotriene A4 hydrolase) Mus musculus
Symbol: Lta4h
Name: leukotriene A4 hydrolase
RGD ID: 1322732
Description: Predicted to have ether hydrolase activity; metalloaminopeptidase activity; and zinc ion binding activity. Predicted to be involved in several processes, including cellular lipid metabolic process; leukotriene biosynthetic process; and peptide catabolic process. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human LTA4H (leukotriene A4 hydrolase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4 hydrodase
Homo sapiens (human) : LTA4H (leukotriene A4 hydrolase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lta4h (leukotriene A4 hydrolase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lta4h (leukotriene A4 hydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : LTA4H (leukotriene A4 hydrolase)
Canis lupus familiaris (dog) : LTA4H (leukotriene A4 hydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lta4h (leukotriene A4 hydrolase)
Sus scrofa (pig) : LTA4H (leukotriene A4 hydrolase)
Chlorocebus sabaeus (African green monkey) : LTA4H (leukotriene A4 hydrolase)
Heterocephalus glaber (naked mole-rat) : Lta4h (leukotriene A4 hydrolase)
more info ...
Related Pseudogenes: Gm4854  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391093,289,258 - 93,320,758 (+)NCBI
GRCm381093,453,396 - 93,484,896 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1093,453,411 - 93,484,875 (+)EnsemblGRCm38mm10GRCm38
MGSCv371092,916,141 - 92,947,641 (+)NCBIGRCm37mm9NCBIm37
MGSCv361092,883,229 - 92,914,633 (+)NCBImm8
Celera1095,436,799 - 95,470,679 (+)NCBICelera
Cytogenetic Map10C2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lta4h
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322732
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.