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Gene: Egr2 (early growth response 2) Mus musculus
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Symbol: Egr2
Name: early growth response 2
Description: ENCODES a protein that exhibits chromatin binding; DNA binding; DNA-binding transcription factor activity; INVOLVED IN brain segmentation; cellular response to organic substance; facial nerve structural organization; PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH abnormal abducens nerve morphology; abnormal aortic valve cusp morphology; abnormal aortic valve morphology; ASSOCIATED WITH autistic disorder (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 1 (ortholog); FOUND IN cytoplasm; nucleus; intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response protein 2; Egr-2; Krox-20; Krox20; NGF1-B; Zfp-25; Zfp-6; zinc finger protein Krox-20
Orthologs:
Homo sapiens (human) : EGR2 (early growth response 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egr2 (early growth response 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egr2 (early growth response 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EGR2 (early growth response 2)
Canis lupus familiaris (dog) : EGR2 (early growth response 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egr2 (early growth response 2)
Sus scrofa (pig) : EGR2 (early growth response 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381067,534,469 - 67,542,188 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371067,000,617 - 67,004,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv361066,933,235 - 66,937,545 (+)NCBImm8
Celera1068,629,352 - 68,633,671 (+)NCBICelera
Cytogenetic Map10 B5.1NCBI
cM Map1034.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Egr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733541
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.