Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Egr2 (early growth response 2) Mus musculus
Symbol: Egr2
Name: early growth response 2
Description: ENCODES a protein that exhibits chromatin binding; DNA binding; DNA-binding transcription factor activity; INVOLVED IN brain segmentation; cellular response to organic substance; facial nerve structural organization; PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH abnormal abducens nerve morphology; abnormal aortic valve cusp morphology; abnormal aortic valve morphology; ASSOCIATED WITH autistic disorder (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 1 (ortholog); FOUND IN cytoplasm; nucleus; intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response protein 2; Egr-2; Krox-20; Krox20; NGF1-B; Zfp-25; Zfp-6; zinc finger protein Krox-20
Homo sapiens (human) : EGR2 (early growth response 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egr2 (early growth response 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egr2 (early growth response 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EGR2 (early growth response 2)
Canis lupus familiaris (dog) : EGR2 (early growth response 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egr2 (early growth response 2)
Sus scrofa (pig) : EGR2 (early growth response 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381067,534,469 - 67,542,188 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371067,000,617 - 67,004,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv361066,933,235 - 66,937,545 (+)NCBImm8
Celera1068,629,352 - 68,633,671 (+)NCBICelera
Cytogenetic Map10 B5.1NCBI
cM Map1034.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Egr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733541
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.