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Gene: Fosl2 (fos-like antigen 2) Mus musculus
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Symbol: Fosl2
Name: fos-like antigen 2
Description: Exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in keratinocyte development; positive regulation of fibroblast proliferation; and positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in several structures, including alimentary system; genitourinary system; skeleton; skin; and telencephalon. Used to study idiopathic pulmonary fibrosis and systemic scleroderma. Orthologous to human FOSL2 (FOS like 2, AP-1 transcription factor subunit); INTERACTS WITH (S)-amphetamine; 1,1-dichloroethene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fos-related antigen 2; Fra-2
Orthologs:
Homo sapiens (human) : FOSL2 (FOS like 2, AP-1 transcription factor subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fosl2 (FOS like 2, AP-1 transcription factor subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fosl2 (FOS like 2, AP-1 transcription factor subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : FOSL2 (FOS like 2, AP-1 transcription factor subunit)
Canis lupus familiaris (dog) : FOSL2 (FOS like 2, AP-1 transcription factor subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fosl2 (FOS like 2, AP-1 transcription factor subunit)
Sus scrofa (pig) : FOSL2 (FOS like 2, AP-1 transcription factor subunit)
Chlorocebus sabaeus (African green monkey) : FOSL2 (FOS like 2, AP-1 transcription factor subunit)
Heterocephalus glaber (naked mole-rat) : Fosl2 (FOS like 2, AP-1 transcription factor subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl532,135,801 - 32,157,842 (+)EnsemblGRCm38mm10GRCm38
GRCm38532,136,472 - 32,157,840 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37532,438,845 - 32,460,213 (+)NCBIGRCm37mm9NCBIm37
MGSCv36530,804,839 - 30,826,510 (+)NCBImm8
MGSCv36532,413,115 - 32,434,421 (+)NCBImm8
Celera529,588,696 - 29,629,647 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fosl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10598
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.