(+)-taxifolin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]] more ... CTD PMID:35465754 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA] more ... CTD PMID:36056792 and PMID:37286014 (-)-epigallocatechin 3-gallate multiple interactions ISO NLRP3 (Homo sapiens) 6480464 epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA] and epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein] CTD PMID:35439536 (20S)-ginsenoside Rg3 multiple interactions EXP 6480464 ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:34423507 (20S)-ginsenoside Rg3 multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]] and ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:34423507 (S)-nicotine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased expression of NLRP3 protein] CTD PMID:35131329 (S)-nicotine increases expression ISO NLRP3 (Homo sapiens) 6480464 Nicotine results in increased expression of NLRP3 protein CTD PMID:35131329 (S)-ropivacaine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein] and NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein]] CTD PMID:36858639 (S)-ropivacaine increases expression ISO NLRP3 (Homo sapiens) 6480464 Ropivacaine results in increased expression of NLRP3 protein CTD PMID:36858639 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of NLRP3 protein CTD PMID:37150348 1,2-dichloroethane multiple interactions EXP 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of NLRP3 protein and allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of NLRP3 protein] CTD PMID:37150348 1,4-phenylenediamine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] CTD PMID:31276767 1,4-phenylenediamine increases expression ISO NLRP3 (Homo sapiens) 6480464 4-phenylenediamine results in increased expression of NLRP3 protein CTD PMID:31276767 1-chloro-2,4-dinitrobenzene increases expression ISO NLRP3 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of NLRP3 protein CTD PMID:31276767 1-chloro-2,4-dinitrobenzene multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] CTD PMID:31276767 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:32968928 and PMID:38016618 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:32968928 and PMID:38016618 17beta-estradiol multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of NLRP3 mRNA CTD PMID:30165855 17beta-estradiol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of NLRP3 mRNA CTD PMID:32741896 17beta-estradiol 3-benzoate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of NLRP3 mRNA CTD PMID:32741896 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of NLRP3 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of NLRP3 mRNA CTD PMID:33387578 and PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 KL protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [lipopolysaccharide more ... CTD PMID:29885354 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] CTD PMID:30365937 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein CTD PMID:30365937 2,4-D multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:34464015 2,4-D multiple interactions EXP 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:35099110 2,4-D increases expression EXP 6480464 2 more ... CTD PMID:35099110 2,4-D increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 2 more ... CTD PMID:34464015 2,5-hexanedione increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32522579 and PMID:32860822 2,5-hexanedione multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Glyburide inhibits the reaction [2 and 5-hexanedione results in increased expression of NLRP3 protein] CTD PMID:32522579 and PMID:32860822 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Verapamil inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 mRNA] and Verapamil inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] CTD PMID:35460826 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein and S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein] CTD PMID:32453893 3-chloropropane-1,2-diol increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of NLRP3 protein CTD PMID:33187795 3-chloropropane-1,2-diol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of NLRP3 protein] and glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of NLRP3 protein] CTD PMID:33187795 3-mercaptopropanoic acid multiple interactions EXP 6480464 [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of NLRP3 mRNA and [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of NLRP3 protein CTD PMID:29852215 3-methyladenine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]] more ... CTD PMID:30205151 more ... 3-methyladenine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of NLRP3 protein] CTD PMID:37169277 4,4'-sulfonyldiphenol affects methylation EXP 6480464 bisphenol S affects the methylation of NLRP3 gene CTD PMID:31683443 4-hydroxynon-2-enal increases expression EXP 6480464 4-hydroxy-2-nonenal results in increased expression of NLRP3 mRNA CTD PMID:19191707 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester multiple interactions EXP 6480464 Carticaine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:32687258 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of NLRP3 mRNA] more ... CTD PMID:30796460 and PMID:37692514 4-phenylbutyric acid multiple interactions ISO NLRP3 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 and PMID:36646296 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]] and Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 6-propyl-2-thiouracil increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of NLRP3 mRNA and Propylthiouracil results in increased expression of NLRP3 protein CTD PMID:37047793 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Uric Acid co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein more ... CTD PMID:18403674 and PMID:18604214 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases response to substance EXP 6480464 NLRP3 gene mutant form results in decreased susceptibility to Uric Acid CTD PMID:23619996 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Uric Acid] affects the localization of NLRP3 protein more ... CTD PMID:18403674 more ... 7-ketocholesterol affects localization EXP 6480464 7-ketocholesterol affects the localization of NLRP3 protein CTD PMID:28633109 7-ketocholesterol multiple interactions EXP 6480464 Amitriptyline inhibits the reaction [7-ketocholesterol affects the localization of NLRP3 protein] CTD PMID:28633109 acetamide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 acetamide results in increased expression of NLRP3 mRNA CTD PMID:31881176 acetic acid increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Acetic Acid results in increased expression of NLRP3 mRNA and Acetic Acid results in increased expression of NLRP3 protein CTD PMID:30408459 and PMID:35595039 acetic acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Plant Extracts inhibits the reaction [Acetic Acid results in increased expression of NLRP3 protein] more ... CTD PMID:30408459 and PMID:35595039 acetylsalicylic acid affects response to substance ISO NLRP3 (Homo sapiens) 6480464 NLRP3 SNP affects the susceptibility to Aspirin CTD PMID:19767079 aconitine increases expression EXP 6480464 Aconitine results in increased expression of NLRP3 protein CTD PMID:33236894 aconitine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 NLRP3 protein affects the reaction [Aconitine results in increased expression of CASP1 protein] more ... CTD PMID:33236894 aconitine increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Aconitine results in increased expression of NLRP3 protein CTD PMID:33236894 acrolein multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 3-(formylhydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid (2 more ... CTD PMID:31639409 acrolein increases expression ISO NLRP3 (Homo sapiens) 6480464 Acrolein results in increased expression of NLRP3 protein CTD PMID:34238121 and PMID:36055550 acrolein multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein] more ... CTD PMID:30205151 more ... acrolein increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Acrolein results in increased expression of NLRP3 protein CTD PMID:31639409 acrylamide decreases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of NLRP3 mRNA CTD PMID:28959563 acrylamide affects response to substance EXP 6480464 NLRP3 gene mutant form affects the susceptibility to Acrylamide CTD PMID:32014472 acrylamide multiple interactions EXP 6480464 [NLRP3 gene mutant form affects the susceptibility to Acrylamide] which results in increased expression of HMOX1 protein more ... CTD PMID:31073625 and PMID:32014472 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of NLRP3 protein CTD PMID:31073625 and PMID:32014472 acrylamide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of NLRP3 mRNA and Acrylamide results in increased expression of NLRP3 protein CTD PMID:31073625 actinomycin D multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [Asbestos and Crocidolite results in increased expression of NLRP3 mRNA] CTD PMID:23937860 aflatoxin B1 increases methylation ISO NLRP3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of NLRP3 gene CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of NLRP3 mRNA and Aflatoxin B1 results in increased expression of NLRP3 protein CTD PMID:35063475 aflatoxin B1 multiple interactions EXP 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 protein] CTD PMID:35063475 aldehydo-D-glucose increases response to substance EXP 6480464 NLRP3 protein results in increased susceptibility to Glucose CTD PMID:27783111 aldehydo-D-glucose multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [Glucose results in decreased expression of TJP1 protein] more ... CTD PMID:27783111 aldehydo-D-glucose multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... aldehydo-D-glucose increases expression ISO NLRP3 (Homo sapiens) 6480464 Glucose results in increased expression of NLRP3 mRNA and Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... aldehydo-D-glucose multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... aldehydo-D-glucose increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... all-trans-retinoic acid increases expression ISO NLRP3 (Homo sapiens) 6480464 Tretinoin results in increased expression of NLRP3 mRNA CTD PMID:33167477 allethrin increases expression ISO NLRP3 (Homo sapiens) 6480464 Allethrins results in increased expression of NLRP3 mRNA CTD PMID:36074087 allicin multiple interactions EXP 6480464 allicin inhibits the reaction [Acetaminophen results in increased expression of NLRP3 protein] CTD PMID:32040233 allopurinol multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:23647015 allopurinol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of NLRP3 protein] more ... CTD PMID:22426011 and PMID:23647015 aluminium hydroxide multiple interactions EXP 6480464 NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 aluminium sulfate (anhydrous) multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein] CTD PMID:24158569 amitriptyline multiple interactions EXP 6480464 Amitriptyline inhibits the reaction [7-ketocholesterol affects the localization of NLRP3 protein] and Amitriptyline inhibits the reaction [Cholesterol analog affects the localization of NLRP3 protein] CTD PMID:28633109 amphetamine increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Amphetamine results in increased expression of NLRP3 mRNA CTD PMID:30779732 amphibole asbestos decreases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Asbestos and Amphibole results in decreased expression of NLRP3 mRNA CTD PMID:27083413 amphibole asbestos increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Asbestos and Amphibole results in increased expression of NLRP3 mRNA CTD PMID:22168577 anthocyanin multiple interactions EXP 6480464 Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NLRP3 protein] CTD PMID:24795233 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO NLRP3 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein] and pyrazolanthrone inhibits the reaction [APP protein results in increased expression of NLRP3 protein] CTD PMID:28004443 and PMID:34510229 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA] CTD PMID:30259999 antirheumatic drug decreases expression ISO NLRP3 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of NLRP3 mRNA CTD PMID:24449571 apigenin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Apigenin analog inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]] more ... CTD PMID:36055550 apocynin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein] CTD PMID:26901245 aripiprazole multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of NLRP3 mRNA CTD PMID:31476115 aristolochic acid A increases expression ISO NLRP3 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of NLRP3 mRNA CTD PMID:33212167 arsane affects methylation ISO NLRP3 (Homo sapiens) 6480464 Arsenic affects the methylation of NLRP3 gene CTD PMID:25304211 arsane multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein and bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein] CTD PMID:32645460 arsenic atom affects methylation ISO NLRP3 (Homo sapiens) 6480464 Arsenic affects the methylation of NLRP3 gene CTD PMID:25304211 arsenic atom multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein and bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein] CTD PMID:32645460 arsenite(3-) multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of NLRP3 mRNA CTD PMID:36791901 arsenous acid increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:30660605 arsenous acid increases expression ISO NLRP3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of NLRP3 mRNA and Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:35226250 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:30237538 and PMID:35226250 arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of NLRP3 mRNA more ... CTD PMID:30237538 more ... arsenous acid multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with lipopolysaccharide more ... CTD PMID:30237538 and PMID:35226250 arsenous acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein more ... CTD PMID:30660605 artesunate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 artesunate inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:30031708 asbestos affects response to substance ISO NLRP3 (Homo sapiens) 6480464 NLRP3 gene SNP affects the susceptibility to Asbestos CTD PMID:24142982 astragaloside IV multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 astragaloside A inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:30842369 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA] CTD PMID:37023836 atorvastatin calcium multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein] CTD PMID:34939712 ATP multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Adenosine Triphosphate co-treated with lipopolysaccharide more ... CTD PMID:18604214 more ... ATP multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein more ... CTD PMID:35962723 ATP multiple interactions EXP 6480464 [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA more ... CTD PMID:18604214 more ... atrazine decreases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of NLRP3 mRNA CTD PMID:36841081 atropine increases expression ISO NLRP3 (Homo sapiens) 6480464 Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 aucubin multiple interactions EXP 6480464 aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein] CTD PMID:35961541 aucubin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein] CTD PMID:35961541 aurantio-obtusin increases expression EXP 6480464 aurantio-obtusin results in increased expression of NLRP3 mRNA and aurantio-obtusin results in increased expression of NLRP3 protein CTD PMID:34718095 azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of NLRP3 mRNA CTD PMID:24184165 bafilomycin A1 increases expression ISO NLRP3 (Homo sapiens) 6480464 bafilomycin A1 results in increased expression of NLRP3 protein CTD PMID:32645460 bafilomycin A1 multiple interactions ISO NLRP3 (Homo sapiens) 6480464 bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein] CTD PMID:32645460 baicalin multiple interactions EXP 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:29031535 and PMID:38016618 BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:36308466 benzo[a]pyrene affects methylation ISO NLRP3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of NLRP3 3' UTR and Benzo(a)pyrene affects the methylation of NLRP3 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [IL27 protein co-treated with IFNL3 protein] inhibits the reaction [Benzo(a)pyrene results in increased expression of NLRP3 protein] more ... CTD PMID:34999049 benzo[a]pyrene increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of NLRP3 protein CTD PMID:34999049 benzo[a]pyrene increases methylation ISO NLRP3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of NLRP3 5' UTR CTD PMID:27901495 benzo[a]pyrene diol epoxide I multiple interactions ISO NLRP3 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 benzo[a]pyrene diol epoxide I increases expression ISO NLRP3 (Homo sapiens) 6480464 7 more ... CTD PMID:35297523 benzo[e]pyrene increases methylation ISO NLRP3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of NLRP3 intron CTD PMID:30157460 berberine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of NLRP3 mRNA] CTD PMID:35121005 Bergenin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] CTD PMID:30365937 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of NLRP3 protein CTD PMID:37858774 bis(2-ethylhexyl) phthalate increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of NLRP3 mRNA and Diethylhexyl Phthalate results in increased expression of NLRP3 protein CTD PMID:35460826 bis(2-ethylhexyl) phthalate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 4 more ... CTD PMID:35460826 bisphenol A decreases expression ISO Nlrp3 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of NLRP3 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO NLRP3 (Homo sapiens) 6480464 benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA] more ... CTD PMID:35439536 bisphenol A increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of NLRP3 protein CTD PMID:35465754 bisphenol A multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein] more ... CTD PMID:35465754 bisphenol A increases expression ISO NLRP3 (Homo sapiens) 6480464 bisphenol A results in increased expression of NLRP3 mRNA and bisphenol A results in increased expression of NLRP3 protein CTD PMID:35439536 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Dietary Fats] results in increased expression of NLRP3 protein more ... CTD PMID:33239236 and PMID:33265944 bortezomib decreases expression ISO NLRP3 (Homo sapiens) 6480464 Bortezomib results in decreased expression of NLRP3 mRNA CTD PMID:17659339 bortezomib multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of NLRP3 mRNA] CTD PMID:35121005 bortezomib increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Bortezomib results in increased expression of NLRP3 mRNA CTD PMID:35121005 buspirone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Buspirone inhibits the reaction [Methotrexate results in increased expression of NLRP3 protein] CTD PMID:37341015 buta-1,3-diene decreases expression EXP 6480464 1 and 3-butadiene results in decreased expression of NLRP3 mRNA CTD PMID:29038090 butanal increases expression ISO NLRP3 (Homo sapiens) 6480464 butyraldehyde results in increased expression of NLRP3 mRNA CTD PMID:26079696 cadmium atom increases expression ISO NLRP3 (Homo sapiens) 6480464 Cadmium results in increased expression of NLRP3 mRNA CTD PMID:33559965 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein CTD PMID:33359024 cadmium atom multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 mRNA more ... CTD PMID:34510229 and PMID:35384154 cadmium atom multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein] more ... CTD PMID:34510229 and PMID:37300869 cadmium dichloride multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein] more ... CTD PMID:26809137 more ... cadmium dichloride multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 mRNA more ... CTD PMID:34510229 and PMID:35384154 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of NLRP3 protein CTD PMID:30796460 cadmium dichloride multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of NLRP3 mRNA] more ... CTD PMID:30796460 and PMID:33359024 cadmium dichloride increases expression ISO NLRP3 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of NLRP3 mRNA and Cadmium Chloride results in increased expression of NLRP3 protein CTD PMID:30796460 cannabidiol multiple interactions ISO NLRP3 (Homo sapiens) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]] more ... CTD PMID:27932991 and PMID:34269108 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of NLRP3 protein CTD PMID:34269108 cannabidiol decreases expression ISO NLRP3 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of NLRP3 mRNA and Cannabidiol results in decreased expression of NLRP3 protein CTD PMID:27932991 and PMID:34269108 CCCP multiple interactions EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 CCCP multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 celastrol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA] more ... CTD PMID:32470352 CGP 52608 multiple interactions ISO NLRP3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to NLRP3 gene] CTD PMID:28238834 chlorpyrifos multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of NLRP3 protein] more ... CTD PMID:26435000 and PMID:30835941 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of NLRP3 mRNA CTD PMID:33839396 chlorpyrifos increases expression ISO NLRP3 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of NLRP3 mRNA and Chlorpyrifos results in increased expression of NLRP3 protein CTD PMID:26435000 and PMID:30835941 chlorquinaldol multiple interactions EXP 6480464 Chlorquinaldol inhibits the reaction [NLRP3 protein binds to PYCARD protein] CTD PMID:36002070 cholesterol affects localization EXP 6480464 Cholesterol analog affects the localization of NLRP3 protein CTD PMID:28633109 cholesterol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Cholesterol co-treated with Ergosterol] results in increased expression of NLRP3 mRNA more ... CTD PMID:25833014 cholesterol multiple interactions EXP 6480464 [Cholesterol co-treated with bisphenol A] results in increased expression of NLRP3 protein more ... CTD PMID:28633109 and PMID:33239236 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA more ... CTD PMID:34416350 and PMID:37023836 cisplatin multiple interactions EXP 6480464 3-(5-(2 more ... CTD PMID:25308879 and PMID:34423507 cisplatin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]] and ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:34423507 cisplatin increases expression ISO NLRP3 (Homo sapiens) 6480464 Cisplatin results in increased expression of NLRP3 protein CTD PMID:34423507 cisplatin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 astragaloside A inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] more ... CTD PMID:30842369 and PMID:32418911 cisplatin increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of NLRP3 protein CTD PMID:30842369 and PMID:32418911 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of NLRP3 protein CTD PMID:25308879 more ... cobalt atom multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of NLRP3 mRNA more ... CTD PMID:18078969 and PMID:32805375 cobalt atom increases expression ISO NLRP3 (Homo sapiens) 6480464 Cobalt results in increased expression of NLRP3 protein CTD PMID:32805375 copper(II) sulfate multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of NLRP3 protein] and roflupram inhibits the reaction [Copper Sulfate results in increased expression of NLRP3 protein] CTD PMID:37353053 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of NLRP3 protein CTD PMID:37353053 corilagin multiple interactions EXP 6480464 corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein] more ... CTD PMID:37394652 crocidolite asbestos increases expression ISO NLRP3 (Homo sapiens) 6480464 Asbestos more ... CTD PMID:23937860 and PMID:24885895 crocidolite asbestos multiple interactions EXP 6480464 NLRP3 protein affects the reaction [Asbestos more ... CTD PMID:18403674 crocidolite asbestos multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [Asbestos more ... CTD PMID:18403674 more ... Cuprizon increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Cuprizone results in increased expression of NLRP3 mRNA CTD PMID:27523638 curcumin multiple interactions EXP 6480464 [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide more ... CTD PMID:34998855 and PMID:35063475 Curcumol decreases expression ISO NLRP3 (Homo sapiens) 6480464 curcumol results in decreased expression of NLRP3 protein CTD PMID:32344006 cycloheximide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of NLRP3 protein] CTD PMID:26901245 cyclophosphamide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]] and Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] CTD PMID:35762198 cyclophosphamide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of NLRP3 protein CTD PMID:35762198 cyclosporin A increases expression ISO NLRP3 (Homo sapiens) 6480464 Cyclosporine results in increased expression of NLRP3 mRNA CTD PMID:34681664 D-glucose increases expression ISO NLRP3 (Homo sapiens) 6480464 Glucose results in increased expression of NLRP3 mRNA and Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... D-glucose multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [Glucose results in decreased expression of TJP1 protein] more ... CTD PMID:27783111 D-glucose increases response to substance EXP 6480464 NLRP3 protein results in increased susceptibility to Glucose CTD PMID:27783111 D-glucose multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... D-glucose multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... D-glucose increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... dapagliflozin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein] CTD PMID:34939712 deoxynivalenol multiple interactions EXP 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA] more ... CTD PMID:36309173 deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of NLRP3 mRNA and deoxynivalenol results in increased expression of NLRP3 protein CTD PMID:36309173 desipramine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Desipramine inhibits the reaction [Silicon Dioxide results in increased expression of NLRP3 protein] CTD PMID:34969174 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide more ... CTD PMID:30102002 more ... dexmedetomidine multiple interactions EXP 6480464 Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:30102002 dexmedetomidine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein] and NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein]] CTD PMID:36858639 dextran sulfate increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Dextran Sulfate results in increased expression of NLRP3 mRNA CTD PMID:32470352 dextran sulfate multiple interactions EXP 6480464 [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein more ... CTD PMID:27611972 more ... dextran sulfate increases expression EXP 6480464 Dextran Sulfate results in increased expression of NLRP3 mRNA and Dextran Sulfate results in increased expression of NLRP3 protein CTD PMID:30270565 and PMID:37001609 dextran sulfate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA] more ... CTD PMID:32470352 diallyl disulfide multiple interactions EXP 6480464 diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein] more ... CTD PMID:34896185 and PMID:35526736 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of NLRP3 protein] CTD PMID:37150348 diallyl trisulfide multiple interactions EXP 6480464 diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] affects the localization of NLRP3 protein] and diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]] CTD PMID:36796188 diarsenic trioxide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with lipopolysaccharide more ... CTD PMID:30237538 and PMID:35226250 diarsenic trioxide increases expression ISO NLRP3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of NLRP3 mRNA and Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:35226250 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:30237538 and PMID:35226250 diarsenic trioxide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein more ... CTD PMID:30660605 diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of NLRP3 mRNA more ... CTD PMID:30237538 more ... diarsenic trioxide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of NLRP3 protein CTD PMID:30660605 dibutyl phthalate multiple interactions ISO NLRP3 (Homo sapiens) 6480464 KN 62 inhibits the reaction [Dibutyl Phthalate results in increased expression of NLRP3 protein] CTD PMID:26586371 dibutyl phthalate increases expression ISO NLRP3 (Homo sapiens) 6480464 Dibutyl Phthalate results in increased expression of NLRP3 protein CTD PMID:26586371 diclofenac increases expression ISO NLRP3 (Homo sapiens) 6480464 Diclofenac results in increased expression of NLRP3 mRNA CTD PMID:28138970 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of NLRP3 mRNA CTD PMID:24747151 dicloxacillin increases expression EXP 6480464 Dicloxacillin results in increased expression of NLRP3 mRNA CTD PMID:24747151 diethyldithiocarbamic acid affects expression EXP 6480464 Ditiocarb affects the expression of NLRP3 protein CTD PMID:25929180 diethyldithiocarbamic acid multiple interactions EXP 6480464 [Ditiocarb co-treated with Zinc] results in decreased expression of NLRP3 protein CTD PMID:25929180 dihydroartemisinin multiple interactions ISO Nlrp3 (Rattus norvegicus) 15036816 Dihydroartemisinin inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver] RGD dimethyl fumarate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein] and Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein] CTD PMID:36999408 dimethyldithiocarbamate affects expression EXP 6480464 Dimethyldithiocarbamate affects the expression of NLRP3 protein CTD PMID:25929180 diosmetin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein] CTD PMID:35191607 dioxygen multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 mRNA] more ... CTD PMID:26464617 more ... doxorubicin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 MAPK1 promotes the reaction [Doxorubicin results in increased expression of NLRP3 mRNA] CTD PMID:24885895 doxorubicin increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of NLRP3 mRNA and Doxorubicin results in increased expression of NLRP3 protein CTD PMID:35764897 doxorubicin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 HDAC6 protein promotes the reaction [Doxorubicin results in increased expression of NLRP3 mRNA] more ... CTD PMID:35764897 doxorubicin increases expression ISO NLRP3 (Homo sapiens) 6480464 Doxorubicin results in increased expression of NLRP3 mRNA CTD PMID:24885895 elemental selenium increases expression ISO NLRP3 (Homo sapiens) 6480464 Selenium results in increased expression of NLRP3 mRNA CTD PMID:17293063 emodin multiple interactions EXP 6480464 Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA] CTD PMID:37023836 endosulfan increases expression ISO NLRP3 (Homo sapiens) 6480464 Endosulfan results in increased expression of NLRP3 mRNA CTD PMID:28108160 ergosterol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Cholesterol co-treated with Ergosterol] results in increased expression of NLRP3 mRNA more ... CTD PMID:25833014 eriodictyol multiple interactions EXP 6480464 eriodictyol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:31860763 Erionite increases expression ISO NLRP3 (Homo sapiens) 6480464 erionite results in increased expression of NLRP3 mRNA CTD PMID:23937860 ethanol increases expression ISO Nlrp3 (Rattus norvegicus) 15036816 ethanol increases expression of Nrlp3 protein in liver RGD ethanol increases expression EXP 6480464 Ethanol results in increased expression of NLRP3 protein CTD PMID:35526736 ethanol multiple interactions EXP 6480464 [Ethanol co-treated with High Fructose Corn Syrup co-treated with lard] results in increased expression of NLRP3 protein more ... CTD PMID:35526736 more ... ethanol increases expression ISO NLRP3 (Homo sapiens) 6480464 Ethanol results in increased expression of NLRP3 protein CTD PMID:34474091 ethanol multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein more ... CTD PMID:28964808 and PMID:34474091 flutamide increases expression ISO NLRP3 (Homo sapiens) 6480464 Flutamide results in increased expression of NLRP3 mRNA CTD PMID:28138970 flutamide increases expression EXP 6480464 Flutamide results in increased expression of NLRP3 mRNA CTD PMID:28138970 fluvastatin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein] more ... CTD PMID:35465754 formaldehyde decreases expression ISO NLRP3 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of NLRP3 mRNA CTD PMID:28937961 formononetin multiple interactions EXP 6480464 formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA] CTD PMID:37269934 fructose multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein] more ... CTD PMID:22426011 more ... fructose increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Fructose results in increased expression of NLRP3 protein CTD PMID:22426011 and PMID:24491314 fulvestrant multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA] and Fulvestrant inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein] CTD PMID:35439536 fumonisin B1 multiple interactions EXP 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA] more ... CTD PMID:36309173 fumonisin B1 increases expression EXP 6480464 fumonisin B1 results in increased expression of NLRP3 mRNA and fumonisin B1 results in increased expression of NLRP3 protein CTD PMID:36309173 furan increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 furan results in increased expression of NLRP3 mRNA CTD PMID:27387713 furan multiple interactions EXP 6480464 rhodioloside inhibits the reaction [furan results in increased expression of NLRP3 protein] CTD PMID:34450210 furan increases expression EXP 6480464 furan results in increased expression of NLRP3 protein CTD PMID:34450210 furosemide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein CTD PMID:29860548 Fusaric acid decreases expression ISO NLRP3 (Homo sapiens) 6480464 Fusaric Acid results in decreased expression of NLRP3 mRNA CTD PMID:30582969 galangin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 galangin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein] CTD PMID:35384154 genkwanin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein] and TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]] CTD PMID:34481870 gentamycin increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of NLRP3 mRNA CTD PMID:33387578 glucose increases expression ISO NLRP3 (Homo sapiens) 6480464 Glucose results in increased expression of NLRP3 mRNA and Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... glucose increases response to substance EXP 6480464 NLRP3 protein results in increased susceptibility to Glucose CTD PMID:27783111 glucose multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [Glucose results in decreased expression of TJP1 protein] more ... CTD PMID:27783111 glucose increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Glucose results in increased expression of NLRP3 protein CTD PMID:23647015 more ... glucose multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... glucose multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein more ... CTD PMID:23647015 more ... glyburide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein] more ... CTD PMID:25338942 more ... glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein] more ... CTD PMID:32167222 more ... glycerol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Pentoxifylline inhibits the reaction [Glycerol results in increased expression of NLRP3 protein] and Thiamine inhibits the reaction [Glycerol results in increased expression of NLRP3 protein] CTD PMID:36690085 glycerol increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Glycerol results in increased expression of NLRP3 protein CTD PMID:36690085 glycidol increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 glycidol results in increased expression of NLRP3 protein CTD PMID:33187795 glycidol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of NLRP3 protein] and glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of NLRP3 protein] CTD PMID:33187795 glyphosate increases methylation ISO Nlrp3 (Rattus norvegicus) 6480464 Glyphosate results in increased methylation of NLRP3 gene CTD PMID:31011160 graphene oxide increases expression ISO NLRP3 (Homo sapiens) 6480464 graphene oxide results in increased expression of NLRP3 mRNA CTD PMID:33973267 guggulsterone multiple interactions ISO Nlrp3 (Rattus norvegicus) 15036816 Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver]] RGD GW 4064 multiple interactions EXP 6480464 GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of NLRP3 protein] CTD PMID:36328986 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of NLRP3 protein CTD PMID:29031535 hexadecanoic acid increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Palmitic Acid results in increased expression of NLRP3 mRNA and Palmitic Acid results in increased expression of NLRP3 protein CTD PMID:30259999 and PMID:37244597 hexadecanoic acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA] more ... CTD PMID:30259999 and PMID:37244597 hexadecanoic acid multiple interactions EXP 6480464 baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] more ... CTD PMID:27689324 and PMID:29031535 HU-308 multiple interactions EXP 6480464 [HU 308 co-treated with Dextran Sulfate] affects the expression of NLRP3 protein CTD PMID:27611972 hyaluronic acid increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Hyaluronic Acid results in increased expression of NLRP3 mRNA and Hyaluronic Acid results in increased expression of NLRP3 protein CTD PMID:33383130 hydrogen chloride increases expression EXP 6480464 Hydrochloric Acid results in increased expression of NLRP3 protein CTD PMID:31900028 hydrogen peroxide decreases response to substance EXP 6480464 NLRP3 gene mutant form results in decreased susceptibility to Hydrogen Peroxide CTD PMID:23619996 hydrogen sulfide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in increased expression of NLRP3 protein] and NFE2L2 protein affects the reaction [[sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in increased expression of NLRP3 protein]] CTD PMID:32064027 hydroquinone increases expression ISO NLRP3 (Homo sapiens) 6480464 hydroquinone results in increased expression of NLRP3 protein CTD PMID:36646296 hydroquinone multiple interactions ISO NLRP3 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein] more ... CTD PMID:36646296 hydroxysafflor yellow A multiple interactions EXP 6480464 hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein] CTD PMID:37001609 icariin increases expression ISO NLRP3 (Homo sapiens) 6480464 icariin results in increased expression of NLRP3 mRNA and icariin results in increased expression of NLRP3 protein CTD PMID:35532261 iohexol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein CTD PMID:29860548 isoflurane increases expression EXP 6480464 Isoflurane results in increased expression of NLRP3 protein CTD PMID:35187972 isoflurane multiple interactions EXP 6480464 N-(1 more ... CTD PMID:35187972 JTE-013 multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of NLRP3 protein] CTD PMID:37169277 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of NLRP3 mRNA CTD PMID:28138970 ketoconazole increases expression ISO NLRP3 (Homo sapiens) 6480464 Ketoconazole results in increased expression of NLRP3 mRNA CTD PMID:28138970 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA more ... CTD PMID:34416350 and PMID:37023836 lead diacetate multiple interactions EXP 6480464 1 more ... CTD PMID:36308466 lead diacetate increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 lead acetate results in increased expression of NLRP3 mRNA CTD PMID:37471654 lead diacetate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 sinapinic acid inhibits the reaction [lead acetate results in increased expression of NLRP3 mRNA] CTD PMID:37471654 lead(0) multiple interactions EXP 6480464 1 more ... CTD PMID:36308466 lead(0) multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Lead co-treated with Dietary Fats] results in increased expression of NLRP3 protein more ... CTD PMID:37244597 lead(0) increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Lead results in increased expression of NLRP3 protein CTD PMID:37244597 letrozole increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Letrozole results in increased expression of NLRP3 protein CTD PMID:37328115 letrozole multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Letrozole results in increased expression of NLRP3 protein] CTD PMID:37328115 lipopolysaccharide multiple interactions EXP 6480464 1-dodecylsulfonyl-5N more ... CTD PMID:18604214 more ... lipopolysaccharide increases phosphorylation ISO NLRP3 (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of NLRP3 protein CTD PMID:37182445 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of NLRP3 protein CTD PMID:37182445 lipopolysaccharide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of NLRP3 mRNA and Lipopolysaccharides results in increased expression of NLRP3 protein CTD PMID:32418911 and PMID:34464015 lipopolysaccharide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein more ... CTD PMID:30660605 more ... lipopolysaccharide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]] more ... CTD PMID:18604214 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of NLRP3 mRNA and Lipopolysaccharides results in increased expression of NLRP3 protein CTD PMID:22147977 more ... lipopolysaccharide increases expression ISO NLRP3 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of NLRP3 mRNA and Lipopolysaccharides results in increased expression of NLRP3 protein CTD PMID:24747151 more ... lithium carbonate increases expression EXP 6480464 Lithium Carbonate results in increased expression of NLRP3 protein CTD PMID:34984798 lithocholic acid increases expression EXP 6480464 Lithocholic Acid results in increased expression of NLRP3 mRNA and Lithocholic Acid results in increased expression of NLRP3 protein CTD PMID:29794447 lithocholic acid multiple interactions EXP 6480464 Vardenafil Dihydrochloride inhibits the reaction [Lithocholic Acid results in increased expression of NLRP3 mRNA] and Vardenafil Dihydrochloride inhibits the reaction [Lithocholic Acid results in increased expression of NLRP3 protein] CTD PMID:29794447 loganin multiple interactions EXP 6480464 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA] and loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein] CTD PMID:37473909 loganin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of NLRP3 mRNA] and loganin inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:37473909 luteolin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein] CTD PMID:34217685 LY294002 multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein]] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium bisulfide inhibits the reaction [uranyl acetate results in increased expression of NLRP3 protein]] CTD PMID:36094782 and PMID:36898572 lysophosphatidylcholine increases expression ISO NLRP3 (Homo sapiens) 6480464 Lysophosphatidylcholines results in increased expression of NLRP3 protein CTD PMID:34293432 lysophosphatidylcholine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of NLRP3 protein] CTD PMID:34293432 magnesium dihydroxide multiple interactions EXP 6480464 NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein more ... CTD PMID:32375810 and PMID:34052309 mangiferin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 mangiferin affects the reaction [lipopolysaccharide and Escherichia coli O111 B4 affects the expression of NLRP3 protein] CTD PMID:32420661 mebendazole increases expression ISO NLRP3 (Homo sapiens) 6480464 Mebendazole results in increased expression of NLRP3 mRNA CTD PMID:24747151 melatonin decreases expression EXP 6480464 Melatonin results in decreased expression of NLRP3 mRNA CTD PMID:36504304 melatonin multiple interactions EXP 6480464 [Nickel co-treated with Melatonin] results in decreased expression of NLRP3 protein more ... CTD PMID:36504304 memantine multiple interactions EXP 6480464 Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:34474083 mercury atom multiple interactions EXP 6480464 N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of NLRP3 mRNA] CTD PMID:25237059 mercury atom increases expression EXP 6480464 Mercury results in increased expression of NLRP3 mRNA CTD PMID:25237059 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of NLRP3 mRNA CTD PMID:25237059 mercury dichloride multiple interactions EXP 6480464 N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercuric Chloride results in increased expression of NLRP3 mRNA] CTD PMID:25237059 mercury(0) multiple interactions EXP 6480464 N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of NLRP3 mRNA] CTD PMID:25237059 mercury(0) increases expression EXP 6480464 Mercury results in increased expression of NLRP3 mRNA CTD PMID:25237059 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein] CTD PMID:37001609 methamphetamine multiple interactions EXP 6480464 Methamphetamine promotes the reaction [PYCARD protein binds to NLRP3 protein] more ... CTD PMID:30394308 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of NLRP3 protein CTD PMID:30394308 methapyrilene increases methylation ISO NLRP3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of NLRP3 intron CTD PMID:30157460 methimazole multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of NLRP3 mRNA CTD PMID:26177832 methotrexate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Buspirone inhibits the reaction [Methotrexate results in increased expression of NLRP3 protein] CTD PMID:37341015 methotrexate increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Methotrexate results in increased expression of NLRP3 protein CTD PMID:37341015 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of NLRP3 protein CTD PMID:33078829 microcystin-LR multiple interactions EXP 6480464 FOXO1 affects the reaction [cyanoginosin LR results in increased expression of NLRP3 protein] more ... CTD PMID:33078829 and PMID:34416350 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [Morphine results in increased expression of NLRP3 protein] CTD PMID:37394652 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein CTD PMID:31016965 more ... mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein] more ... CTD PMID:37286014 and PMID:37692514 mono(2-ethylhexyl) phthalate increases expression ISO NLRP3 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 mRNA and mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein CTD PMID:33159713 morphine multiple interactions EXP 6480464 corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein] more ... CTD PMID:37394652 morphine increases expression EXP 6480464 Morphine results in increased expression of NLRP3 protein CTD PMID:37394652 Morroniside affects expression EXP 6480464 morroniside affects the expression of NLRP3 CTD PMID:33022338 Morroniside multiple interactions EXP 6480464 morroniside inhibits the reaction [IL1B protein results in increased expression of NLRP3] CTD PMID:33022338 myrtenol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 myrtenol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA] CTD PMID:34477272 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of NLRP3 protein] CTD PMID:37353053 N-acetyl-L-cysteine increases expression ISO NLRP3 (Homo sapiens) 6480464 Acetylcysteine results in increased expression of NLRP3 mRNA and Acetylcysteine results in increased expression of NLRP3 protein CTD PMID:24885895 and PMID:36646296 N-acetyl-L-cysteine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NLRP3 protein] and Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA] CTD PMID:30259999 and PMID:36347317 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA] more ... CTD PMID:26086368 more ... N-acetyl-L-cysteine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:26435000 more ... N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 [1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein more ... CTD PMID:38016618 N-methyl-4-phenylpyridinium multiple interactions ISO NLRP3 (Homo sapiens) 6480464 ELAVL1 protein affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]] more ... CTD PMID:32968928 and PMID:34481870 N-methyl-4-phenylpyridinium increases expression ISO NLRP3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA and 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein CTD PMID:32968928 and PMID:34481870 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of NLRP3 mRNA CTD PMID:17942915 N-nitrosodiethylamine multiple interactions EXP 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NLRP3 mRNA] CTD PMID:17942915 nickel atom increases expression ISO NLRP3 (Homo sapiens) 6480464 Nickel results in increased expression of NLRP3 mRNA CTD PMID:23195993 more ... nickel atom multiple interactions EXP 6480464 [Nickel co-treated with Melatonin] results in decreased expression of NLRP3 protein more ... CTD PMID:36504304 nickel atom multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein and Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein] CTD PMID:31943712 nickel dichloride multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein] CTD PMID:24158569 nickel dichloride multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein and Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein] CTD PMID:31943712 niclosamide multiple interactions EXP 6480464 Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 niclosamide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 nicotine increases expression ISO NLRP3 (Homo sapiens) 6480464 Nicotine results in increased expression of NLRP3 protein CTD PMID:35131329 nicotine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased expression of NLRP3 protein] CTD PMID:35131329 nigericin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 NLRP3 protein affects the reaction [Nigericin results in increased secretion of IL1B protein] CTD PMID:18403674 nigericin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein]] CTD PMID:36898572 NMN zwitterion multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA] and Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein] CTD PMID:30292833 NMN zwitterion multiple interactions EXP 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein] CTD PMID:30292833 Nonylphenol increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of NLRP3 mRNA and nonylphenol results in increased expression of NLRP3 protein CTD PMID:35998786 Nonylphenol increases expression ISO NLRP3 (Homo sapiens) 6480464 nonylphenol results in increased expression of NLRP3 protein CTD PMID:35998786 obeticholic acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 15036816 Obeticholic acid inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver] RGD ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of NLRP3 mRNA and ochratoxin A results in increased expression of NLRP3 protein CTD PMID:33543323 omeprazole multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]] and Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein] CTD PMID:32418911 ozone multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of NLRP3 mRNA CTD PMID:31476115 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of NLRP3 protein and Glyburide inhibits the reaction [Ozone results in increased expression of NLRP3 protein] CTD PMID:26731380 and PMID:32167222 ozone increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Ozone results in increased expression of NLRP3 mRNA CTD PMID:33383130 ozone increases expression EXP 6480464 Ozone results in increased expression of NLRP3 protein CTD PMID:32167222 ozone increases expression ISO NLRP3 (Homo sapiens) 6480464 Ozone results in increased expression of NLRP3 mRNA CTD PMID:31476115 Palbinone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:32202043 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of NLRP3 mRNA CTD PMID:17562736 paracetamol affects expression ISO Nlrp3 (Rattus norvegicus) 6480464 Acetaminophen affects the expression of NLRP3 mRNA CTD PMID:33387578 paracetamol multiple interactions EXP 6480464 allicin inhibits the reaction [Acetaminophen results in increased expression of NLRP3 protein] and PTGES2 protein promotes the reaction [Acetaminophen results in increased expression of NLRP3 protein] CTD PMID:31444509 and PMID:32040233 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of NLRP3 mRNA and Acetaminophen results in increased expression of NLRP3 protein CTD PMID:24747151 more ... paracetamol increases expression ISO NLRP3 (Homo sapiens) 6480464 Acetaminophen results in increased expression of NLRP3 mRNA CTD PMID:26690555 paraquat multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in increased expression of NLRP3 protein] more ... CTD PMID:25338942 more ... paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein more ... CTD PMID:29054699 more ... paraquat increases expression EXP 6480464 Paraquat results in increased expression of NLRP3 protein CTD PMID:29054699 paraquat increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Paraquat results in increased expression of NLRP3 mRNA and Paraquat results in increased expression of NLRP3 protein CTD PMID:25338942 more ... parthenolide multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA] CTD PMID:30259999 patulin increases expression ISO NLRP3 (Homo sapiens) 6480464 Patulin results in increased expression of NLRP3 protein CTD PMID:33217525 patulin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Patulin results in increased expression of NLRP3 protein] more ... CTD PMID:33217525 pentanal increases expression ISO NLRP3 (Homo sapiens) 6480464 pentanal results in increased expression of NLRP3 mRNA CTD PMID:26079696 Pentoxifylline multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Pentoxifylline inhibits the reaction [Glycerol results in increased expression of NLRP3 protein] CTD PMID:36690085 perfluorodecanoic acid multiple interactions ISO NLRP3 (Homo sapiens) 6480464 NLRP3 protein affects the reaction [perfluorodecanoic acid results in increased expression of FASN mRNA] more ... CTD PMID:36423729 perfluorooctanoic acid increases expression ISO NLRP3 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of NLRP3 mRNA CTD PMID:36326898 permethrin multiple interactions EXP 6480464 NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein] more ... CTD PMID:32832901 phenytoin multiple interactions EXP 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of NLRP3 mRNA CTD PMID:23986454 phorbol 13-acetate 12-myristate increases expression ISO NLRP3 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of NLRP3 mRNA CTD PMID:23937860 phosgene increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Phosgene results in increased expression of NLRP3 mRNA and Phosgene results in increased expression of NLRP3 protein CTD PMID:33012731 phosgene multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 NLRP3 protein promotes the reaction [Phosgene results in increased expression of and results in increased activity of CASP1 protein] more ... CTD PMID:33012731 procyanidin B2 multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 procyanidin B2 inhibits the reaction [Paraquat results in increased expression of NLRP3 protein] CTD PMID:30025709 propanal decreases expression ISO NLRP3 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of NLRP3 mRNA CTD PMID:26079696 pterostilbene multiple interactions ISO NLRP3 (Homo sapiens) 6480464 pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein] and RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]] CTD PMID:34474091 puerarin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 puerarin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:35331853 Pyridostigmine bromide multiple interactions EXP 6480464 NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein] more ... CTD PMID:32832901 pyrrolidine dithiocarbamate multiple interactions ISO NLRP3 (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of NLRP3 protein] more ... CTD PMID:35190838 and PMID:36066211 quercetin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] more ... CTD PMID:22426011 more ... quercetin multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Quercetin inhibits the reaction [Glucose results in increased expression of NLRP3 protein] more ... CTD PMID:23647015 and PMID:34791735 raloxifene multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA CTD PMID:19059307 resveratrol multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with Resveratrol] results in increased expression of NLRP3 mRNA and Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein] CTD PMID:24149798 and PMID:31943712 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [[Cholesterol co-treated with bisphenol A] results in increased expression of NLRP3 protein] more ... CTD PMID:33239236 and PMID:34614429 resveratrol multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of NLRP3 mRNA] more ... CTD PMID:25833014 and PMID:26464617 resveratrol increases expression ISO NLRP3 (Homo sapiens) 6480464 resveratrol results in increased expression of NLRP3 mRNA CTD PMID:25436977 Rhein multiple interactions EXP 6480464 rhein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NLRP3 mRNA] CTD PMID:37023836 rifampicin multiple interactions EXP 6480464 Rifampin inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:26086368 rimonabant multiple interactions EXP 6480464 Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1 and 1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3] CTD PMID:32832534 rimonabant multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of NLRP3 protein] CTD PMID:27932991 rosmarinic acid decreases expression ISO NLRP3 (Homo sapiens) 6480464 Rosmarinic Acid results in decreased expression of NLRP3 mRNA CTD PMID:36863647 rotenone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] more ... CTD PMID:23619996 more ... rotenone increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Rotenone results in increased expression of NLRP3 protein CTD PMID:32088201 rotenone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 3-(2 and 4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:32088201 rotenone multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [lipopolysaccharide more ... CTD PMID:30205151 and PMID:30927257 rotenone increases expression EXP 6480464 Rotenone results in increased expression of NLRP3 protein CTD PMID:26086368 and PMID:28903492 rotenone decreases response to substance EXP 6480464 NLRP3 gene mutant form results in decreased susceptibility to Rotenone CTD PMID:28903492 rotenone increases response to substance EXP 6480464 NLRP3 gene results in increased susceptibility to Rotenone CTD PMID:28903492 rutin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] CTD PMID:22426011 S-allylcysteine multiple interactions EXP 6480464 S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein] CTD PMID:32453893 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of NLRP3 mRNA CTD PMID:23986454 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of NLRP3 mRNA CTD PMID:26177832 Salidroside multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 rhodioloside inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:29031534 Salidroside multiple interactions EXP 6480464 rhodioloside inhibits the reaction [furan results in increased expression of NLRP3 protein] CTD PMID:34450210 SB 203580 multiple interactions ISO NLRP3 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein] and SB 203580 inhibits the reaction [APP protein results in increased expression of NLRP3 protein] CTD PMID:28004443 and PMID:34510229 SB 203580 multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [Acrolein results in increased expression of NLRP3 protein] CTD PMID:31639409 scutellarin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:37081038 selenium atom increases expression ISO NLRP3 (Homo sapiens) 6480464 Selenium results in increased expression of NLRP3 mRNA CTD PMID:17293063 serpentine asbestos multiple interactions EXP 6480464 NLRP3 protein affects the reaction [Asbestos more ... CTD PMID:18403674 sevoflurane multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 PHLDA1 protein promotes the reaction [Sevoflurane results in increased expression of NLRP3 protein] and WDR48 protein affects the reaction [Sevoflurane results in increased expression of NLRP3 protein] CTD PMID:36047109 and PMID:36155068 sevoflurane increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Sevoflurane results in increased expression of NLRP3 protein CTD PMID:36047109 and PMID:36155068 silicon dioxide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of NLRP3 mRNA CTD PMID:21602193 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of NLRP3 mRNA and Silicon Dioxide results in increased expression of NLRP3 protein CTD PMID:36309172 silicon dioxide affects localization ISO NLRP3 (Homo sapiens) 6480464 Silicon Dioxide affects the localization of NLRP3 protein CTD PMID:34766707 silicon dioxide increases expression ISO NLRP3 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of NLRP3 mRNA and Silicon Dioxide results in increased expression of NLRP3 protein CTD PMID:33012733 more ... silicon dioxide multiple interactions EXP 6480464 NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased cleavage of CASP1 protein] more ... CTD PMID:18403674 more ... silicon dioxide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Silicon Dioxide co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein more ... CTD PMID:18604214 more ... simvastatin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]] more ... CTD PMID:30408459 and PMID:35762198 sinapic acid multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 sinapinic acid inhibits the reaction [lead acetate results in increased expression of NLRP3 mRNA] CTD PMID:37471654 sirolimus multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein] CTD PMID:30205151 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of NLRP3 protein] and Sirolimus inhibits the reaction [Trichloroethylene results in increased expression of NLRP3 mRNA] CTD PMID:35405287 and PMID:36849104 sirolimus decreases expression ISO NLRP3 (Homo sapiens) 6480464 Sirolimus results in decreased expression of NLRP3 protein CTD PMID:32645460 sodium arsenite multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein and bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein] CTD PMID:32645460 sodium arsenite multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [sodium arsenite co-treated with Lipopolysaccharides] promotes the reaction [SERPINH1 protein binds to NLRP3 protein] more ... CTD PMID:35963424 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of NLRP3 protein CTD PMID:33290778 sodium arsenite multiple interactions EXP 6480464 SEMA4A protein promotes the reaction [sodium arsenite results in increased expression of NLRP3 protein] CTD PMID:33290778 sodium arsenite increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of NLRP3 protein CTD PMID:34920032 sphingosine 1-phosphate multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of NLRP3 protein] more ... CTD PMID:37169277 spironolactone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Letrozole results in increased expression of NLRP3 protein] CTD PMID:37328115 streptozocin multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein] more ... CTD PMID:23647015 more ... streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA more ... CTD PMID:27783111 more ... streptozocin increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of NLRP3 mRNA and Streptozocin results in increased expression of NLRP3 protein CTD PMID:23647015 more ... succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of NLRP3 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of NLRP3 mRNA CTD PMID:21641980 and PMID:26378955 sulfasalazine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of NLRP3 mRNA] and Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of NLRP3 protein] CTD PMID:30408459 and PMID:35595039 sulforaphane multiple interactions EXP 6480464 sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NLRP3 protein] CTD PMID:36988325 tamoxifen multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [Tamoxifen co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA CTD PMID:19059307 taurine multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Taurine inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein] and Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein] CTD PMID:30660605 taurine multiple interactions ISO NLRP3 (Homo sapiens) 6480464 Taurine inhibits the reaction [[Arsenic Trioxide co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased expression of NLRP3 protein] CTD PMID:30237538 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of NLRP3 protein] CTD PMID:30237538 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] CTD PMID:29031535 testosterone increases expression ISO NLRP3 (Homo sapiens) 6480464 Testosterone results in increased expression of NLRP3 mRNA CTD PMID:33359661 testosterone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of NLRP3 mRNA CTD PMID:32741896 tetrachloromethane multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of NLRP3 protein]] more ... CTD PMID:27477297 and PMID:35405287 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of NLRP3 protein CTD PMID:27477297 and PMID:35405287 tetramethylpyrazine multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of NLRP3 protein]] and tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of NLRP3 protein] CTD PMID:27477297 thapsigargin increases expression ISO NLRP3 (Homo sapiens) 6480464 Thapsigargin results in increased expression of NLRP3 mRNA CTD PMID:30796460 thiamine(1+) chloride multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Thiamine inhibits the reaction [Glycerol results in increased expression of NLRP3 protein] CTD PMID:36690085 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of NLRP3 protein CTD PMID:32721574 thioacetamide increases expression ISO Nlrp3 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of NLRP3 mRNA CTD PMID:34492290 thioacetamide multiple interactions EXP 6480464 3-(5-(2 and 3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Thioacetamide results in increased expression of NLRP3 protein] CTD PMID:32721574 thiram affects expression EXP 6480464 Thiram affects the expression of NLRP3 protein CTD PMID:25929180 titanium dioxide decreases expression ISO Nlrp3 (Rattus norvegicus) 6480464 titanium dioxide results in decreased expression of NLRP3 protein CTD PMID:32004531 toluene 2,4-diisocyanate multiple interactions EXP 6480464 N-(1 more ... CTD PMID:31070765 toyocamycin multiple interactions EXP 6480464 Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein] CTD PMID:37692514 trichloroethene multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Trichloroethylene results in increased expression of NLRP3 mRNA] CTD PMID:36849104 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of NLRP3 mRNA CTD PMID:36849104 triclosan increases expression EXP 6480464 Triclosan results in increased expression of NLRP3 mRNA CTD PMID:32321163 triclosan increases expression ISO NLRP3 (Homo sapiens) 6480464 Triclosan results in increased expression of NLRP3 mRNA CTD PMID:34681664 Triptolide increases expression EXP 6480464 triptolide results in increased expression of NLRP3 mRNA CTD PMID:36328986 Triptolide multiple interactions EXP 6480464 [triptolide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 mRNA more ... CTD PMID:36328986 triptonide increases expression EXP 6480464 triptonide results in increased expression of NLRP3 mRNA CTD PMID:33045310 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate increases expression ISO NLRP3 (Homo sapiens) 6480464 Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 Tungsten carbide multiple interactions ISO NLRP3 (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of NLRP3 mRNA CTD PMID:18078969 tunicamycin multiple interactions EXP 6480464 Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]] CTD PMID:37394652 ubiquinone-0 decreases expression ISO NLRP3 (Homo sapiens) 6480464 ubiquinone-O results in decreased expression of NLRP3 protein CTD PMID:36847822 ubiquinone-0 multiple interactions ISO NLRP3 (Homo sapiens) 6480464 ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein] CTD PMID:36847822 verapamil multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 Verapamil inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 mRNA] and Verapamil inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] CTD PMID:35460826 vinclozolin increases methylation ISO Nlrp3 (Rattus norvegicus) 6480464 vinclozolin results in increased methylation of NLRP3 gene CTD PMID:31079544 XL147 multiple interactions EXP 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of NLRP3 mRNA CTD PMID:27935865 zearalenone multiple interactions ISO Nlrp3 (Rattus norvegicus) 6480464 NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form] more ... CTD PMID:31586597 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of NLRP3 mRNA and Zearalenone results in increased expression of NLRP3 protein CTD PMID:30270565 zearalenone multiple interactions EXP 6480464 [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA more ... CTD PMID:30270565 zinc atom multiple interactions EXP 6480464 [Ditiocarb co-treated with Zinc] results in decreased expression of NLRP3 protein CTD PMID:25929180 zinc(0) multiple interactions EXP 6480464 [Ditiocarb co-treated with Zinc] results in decreased expression of NLRP3 protein CTD PMID:25929180 ziram decreases expression EXP 6480464 Ziram results in decreased expression of NLRP3 protein CTD PMID:25929180