Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of PURB mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PURB mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PURB mRNA] | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of PURB mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PURB mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PURB mRNA | CTD | PMID:24058054 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PURB mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PURB mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PURB mRNA | CTD | PMID:17942748 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of PURB gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of PURB mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PURB mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of PURB mRNA | CTD | PMID:16788091 | amitrole | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of PURB mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PURB mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PURB mRNA | CTD | PMID:23650126 | atrazine | increases expression | ISO | PURB (Homo sapiens) | 6480464 | Atrazine results in increased expression of PURB mRNA | CTD | PMID:22378314 | benzene | increases expression | ISO | PURB (Homo sapiens) | 6480464 | Benzene results in increased expression of PURB mRNA | CTD | PMID:15929907 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PURB mRNA | CTD | PMID:20504355 and PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PURB mRNA | CTD | PMID:26238291 | bisphenol A | affects expression | ISO | Purb (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of PURB mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | PURB (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PURB protein | CTD | PMID:34186270 | bisphenol A | decreases expression | ISO | Purb (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PURB mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PURB protein | CTD | PMID:31675489 and PMID:33376534 | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of PURB promoter | CTD | PMID:27334623 | bisphenol A | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PURB mRNA | CTD | PMID:29097150 and PMID:33296240 | caffeine | increases phosphorylation | ISO | PURB (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of PURB protein | CTD | PMID:35688186 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chloropicrin | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of PURB mRNA | CTD | PMID:26352163 | cocaine | affects expression | ISO | Purb (Rattus norvegicus) | 6480464 | Cocaine affects the expression of PURB mRNA | CTD | PMID:20187946 | coumarin | increases phosphorylation | ISO | PURB (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of PURB protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | PURB (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PURB mRNA | CTD | PMID:20106945 | dibutyl phthalate | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of PURB mRNA | CTD | PMID:21266533 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PURB mRNA | CTD | PMID:21266533 | disodium selenite | increases expression | ISO | PURB (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of PURB mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | PURB (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PURB mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PURB mRNA | CTD | PMID:19277126 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of PURB mRNA | CTD | PMID:35436446 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of PURB mRNA | CTD | PMID:34813904 | finasteride | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of PURB mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of PURB mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PURB mRNA] | CTD | PMID:22206623 | FR900359 | increases phosphorylation | ISO | PURB (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of PURB protein | CTD | PMID:37730182 | haloperidol | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Haloperidol results in decreased expression of PURB protein | CTD | PMID:34122009 | leflunomide | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of PURB mRNA | CTD | PMID:24136188 | leflunomide | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | leflunomide results in decreased expression of PURB mRNA | CTD | PMID:28988120 | mercury atom | increases expression | EXP | | 6480464 | Mercury analog results in increased expression of PURB mRNA | CTD | PMID:25056781 | mercury(0) | increases expression | EXP | | 6480464 | Mercury analog results in increased expression of PURB mRNA | CTD | PMID:25056781 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of PURB mRNA | CTD | PMID:26307267 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of PURB mRNA | CTD | PMID:34813904 | methimazole | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of PURB mRNA | CTD | PMID:30047161 | miconazole | decreases expression | EXP | | 6480464 | Miconazole results in decreased expression of PURB mRNA | CTD | PMID:27462272 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PURB mRNA | CTD | PMID:17562736 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of PURB mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of PURB mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | PURB (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PURB mRNA | CTD | PMID:27188386 | propiconazole | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | propiconazole results in increased expression of PURB mRNA | CTD | PMID:30047161 | rotenone | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of PURB mRNA | CTD | PMID:19013527 | SB 431542 | multiple interactions | ISO | PURB (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PURB mRNA | CTD | PMID:27188386 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of PURB protein | CTD | PMID:28918527 | Soman | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Soman results in increased expression of PURB mRNA | CTD | PMID:19281266 | sulfadimethoxine | increases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of PURB mRNA | CTD | PMID:30047161 | tetrachloromethane | multiple interactions | ISO | Purb (Rattus norvegicus) | 6480464 | Carbon Tetrachloride promotes the reaction [PURB protein binds to LGALS3 promoter] | CTD | PMID:16309856 | thimerosal | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of PURB mRNA | CTD | PMID:27188386 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of PURB mRNA | CTD | PMID:23557971 | toluene | decreases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Toluene results in decreased expression of PURB mRNA | CTD | PMID:22967744 | torcetrapib | increases expression | ISO | PURB (Homo sapiens) | 6480464 | torcetrapib results in increased expression of PURB mRNA | CTD | PMID:23228038 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of PURB mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Urethane results in decreased expression of PURB mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | PURB (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PURB mRNA | CTD | PMID:23179753 | valproic acid | decreases expression | ISO | Purb (Rattus norvegicus) | 6480464 | Valproic Acid results in decreased expression of PURB mRNA | CTD | PMID:29427782 | valproic acid | affects expression | ISO | PURB (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PURB mRNA | CTD | PMID:25979313 | zinc atom | multiple interactions | ISO | PURB (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PURB mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | PURB (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PURB mRNA | CTD | PMID:18593933 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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