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Gene: Tfr2 (transferrin receptor 2) Mus musculus
Symbol: Tfr2
Name: transferrin receptor 2
Description: Predicted to have co-receptor binding activity and transferrin receptor activity. Involved in iron ion homeostasis. Localizes to the HFE-transferrin receptor complex. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Is expressed in liver lobe; mesonephros; and urinary system. Orthologous to human TFR2 (transferrin receptor 2); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: transferrin receptor protein 2; Trfr2
Homo sapiens (human) : TFR2 (transferrin receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfr2 (transferrin receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfr2 (transferrin receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TFR2 (transferrin receptor 2)
Canis lupus familiaris (dog) : TFR2 (transferrin receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfr2 (transferrin receptor 2)
Sus scrofa (pig) : TFR2 (transferrin receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl5137,569,840 - 137,587,481 (+)Ensembl
GRCm385137,569,822 - 137,588,081 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375138,011,079 - 138,028,709 (+)NCBIGRCm37mm9NCBIm37
MGSCv365137,800,593 - 137,817,260 (+)NCBImm8
Celera5134,553,508 - 134,571,633 (+)NCBICelera
Cytogenetic Map5 G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tfr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320888
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.