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Gene: Tfr2 (transferrin receptor 2) Mus musculus
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Symbol: Tfr2
Name: transferrin receptor 2
Description: Predicted to have co-receptor binding activity and transferrin receptor activity. Involved in iron ion homeostasis. Localizes to the HFE-transferrin receptor complex. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Is expressed in liver lobe; mesonephros; and urinary system. Orthologous to human TFR2 (transferrin receptor 2); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: transferrin receptor protein 2; Trfr2
Orthologs:
Homo sapiens (human) : TFR2 (transferrin receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfr2 (transferrin receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfr2 (transferrin receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TFR2 (transferrin receptor 2)
Canis lupus familiaris (dog) : TFR2 (transferrin receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfr2 (transferrin receptor 2)
Sus scrofa (pig) : TFR2 (transferrin receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl5137,569,840 - 137,587,481 (+)Ensembl
GRCm385137,569,822 - 137,588,081 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375138,011,079 - 138,028,709 (+)NCBIGRCm37mm9NCBIm37
MGSCv365137,800,593 - 137,817,260 (+)NCBImm8
Celera5134,553,508 - 134,571,633 (+)NCBICelera
Cytogenetic Map5 G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tfr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320888
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.