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Gene: Sh3pxd2b (SH3 and PX domains 2B) Mus musculus
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Symbol: Sh3pxd2b
Name: SH3 and PX domains 2B
Description: Exhibits SH2 domain binding activity and phosphatidylinositol phosphate binding activity. Involved in several processes, including animal organ development; osteoblast fate commitment; and podosome assembly. Localizes to cytoplasm and podosome. Used to study glaucoma and otitis media. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Is expressed in several structures, including branchial arch; central nervous system; heart; jaw; and skeleton. Orthologous to human SH3PXD2B (SH3 and PX domains 2B); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: factor for adipocyte differentiation 49; fad49; G431001E03Rik; RP23-375M9.7; SH3 and PX domain-containing protein 2B; TSK4; tyrosine kinase substrate with four SH3 domains
Orthologs:
Homo sapiens (human) : SH3PXD2B (SH3 and PX domains 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sh3pxd2b (SH3 and PX domains 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3pxd2b (SH3 and PX domains 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3PXD2B (SH3 and PX domains 2B)
Canis lupus familiaris (dog) : SH3PXD2B (SH3 and PX domains 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3pxd2b (SH3 and PX domains 2B)
Sus scrofa (pig) : SH3PXD2B (SH3 and PX domains 2B)
Chlorocebus sabaeus (African green monkey) : SH3PXD2B (SH3 and PX domains 2B)
Heterocephalus glaber (naked mole-rat) : Sh3pxd2b (SH3 and PX domains 2B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1132,347,820 - 32,428,173 (+)EnsemblGRCm38mm10GRCm38
GRCm381132,347,773 - 32,428,189 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371132,247,811 - 32,328,183 (+)NCBIGRCm37mm9NCBIm37
MGSCv361132,247,811 - 32,328,183 (+)NCBImm8
Celera1134,765,291 - 34,845,918 (+)NCBICelera
Cytogenetic Map11A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sh3pxd2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320533
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.