Sh3pxd2b (SH3 and PX domains 2B) - Rat Genome Database

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Gene: Sh3pxd2b (SH3 and PX domains 2B) Mus musculus
Analyze
Symbol: Sh3pxd2b
Name: SH3 and PX domains 2B
RGD ID: 1320533
MGI Page MGI
Description: Enables SH2 domain binding activity and phosphatidylinositol phosphate binding activity. Involved in several processes, including osteoblast fate commitment; podosome assembly; and skeletal system development. Located in cytoplasm and podosome. Is expressed in several structures, including branchial arch; central nervous system; heart; jaw; and skeleton. Used to study glaucoma and otitis media. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: factor for adipocyte differentiation 49; Fad4; fad49; G431001E03Rik; RP23-375M9.7; SH3 and PX domain-containing protein 2B; Tks; Tks4; TSK4; tyrosine kinase substrate with four SH3 domains
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,297,777 - 32,378,189 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,297,820 - 32,378,173 (+)EnsemblGRCm39 Ensembl
GRCm381132,347,773 - 32,428,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,347,820 - 32,428,173 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,247,811 - 32,328,183 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,247,811 - 32,328,183 (+)NCBIMGSCv36mm8
Celera1134,765,291 - 34,845,918 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue development  (IAGP)
abnormal aqueous humor  (IAGP)
abnormal basicranium morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal eye anterior chamber morphology  (IAGP)
abnormal heart shape  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal iliac crest morphology  (IAGP)
abnormal ilium wing morphology  (IAGP)
abnormal iridocorneal angle  (IAGP)
abnormal middle ear morphology  (IAGP)
abnormal mitral valve morphology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal postnatal growth  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina nerve fiber layer morphology  (IAGP)
abnormal sagittal suture morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal tooth morphology  (IAGP)
abnormal xiphoid process morphology  (IAGP)
absent Schlemm's canal  (IAGP)
absent trabecular meshwork  (IAGP)
anterior iris synechia  (IAGP)
cataract  (IAGP)
corneal opacity  (IAGP)
corneal vascularization  (IAGP)
decreased abdominal adipose tissue amount  (IAGP)
decreased body fat mass  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased cornea thickness  (IAGP)
decreased cranium height  (IAGP)
decreased gonadal fat pad weight  (IAGP)
decreased heart rate  (IAGP)
decreased length of long bones  (IAGP)
decreased renal fat pad weight  (IAGP)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased total retina thickness  (IAGP)
decreased white adipose tissue amount  (IAGP)
domed cranium  (IAGP)
enlarged eye anterior chamber  (IAGP)
exophthalmos  (IAGP)
eye inflammation  (IAGP)
female infertility  (IAGP)
gliosis  (IAGP)
hyphema  (IAGP)
hypopyon  (IAGP)
increased cornea size  (IAGP)
increased cornea thickness  (IAGP)
increased eye anterior chamber depth  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased susceptibility to otitis media  (IAGP)
infertility  (IAGP)
irregularly shaped pupil  (IAGP)
kyphosis  (IAGP)
large anterior fontanelle  (IAGP)
lipodystrophy  (IAGP)
lordosis  (IAGP)
male infertility  (IAGP)
mature cataract  (IAGP)
micrognathia  (IAGP)
mitral valve prolapse  (IAGP)
ocular hypertelorism  (IAGP)
ocular hypertension  (IAGP)
optic nerve atrophy  (IAGP)
optic nerve cupping  (IAGP)
optic nerve degeneration  (IAGP)
phthisis bulbi  (IAGP)
posterior subcapsular cataract  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
proportional dwarf  (IAGP)
retina ganglion cell degeneration  (IAGP)
short femur  (IAGP)
short mandible  (IAGP)
short maxilla  (IAGP)
short nasal bone  (IAGP)
short snout  (IAGP)
short tibia  (IAGP)
thin interventricular septum  (IAGP)
Wormian bones  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12477932   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18959745  
PMID:19144821   PMID:19233245   PMID:19669234   PMID:20059953   PMID:20137777   PMID:21267068   PMID:21282566   PMID:21677750   PMID:21818352   PMID:21873635   PMID:25259869   PMID:26234751  
PMID:27711054   PMID:27802184   PMID:28671696   PMID:30333137   PMID:30962481   PMID:31211954   PMID:31387265   PMID:31591456   PMID:32325033   PMID:32554809   PMID:33378226   PMID:35449600  


Genomics

Comparative Map Data
Sh3pxd2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,297,777 - 32,378,189 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,297,820 - 32,378,173 (+)EnsemblGRCm39 Ensembl
GRCm381132,347,773 - 32,428,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,347,820 - 32,428,173 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,247,811 - 32,328,183 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,247,811 - 32,328,183 (+)NCBIMGSCv36mm8
Celera1134,765,291 - 34,845,918 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.89NCBI
SH3PXD2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385172,325,181 - 172,454,525 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5172,325,000 - 172,454,525 (-)EnsemblGRCh38hg38GRCh38
GRCh375171,752,185 - 171,881,529 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,693,108 - 171,814,132 (-)NCBINCBI36Build 36hg18NCBI36
Celera5167,792,626 - 167,913,367 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,855,971 - 166,956,421 (-)NCBIHuRef
CHM1_15171,193,488 - 171,314,268 (-)NCBICHM1_1
T2T-CHM13v2.05172,865,440 - 172,994,533 (-)NCBIT2T-CHM13v2.0
Sh3pxd2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,422,906 - 17,538,977 (+)NCBIGRCr8
mRatBN7.21016,918,611 - 17,027,499 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1016,918,679 - 17,005,170 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1021,668,750 - 21,754,134 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,157,348 - 21,242,732 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,646,426 - 16,733,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,209,152 - 17,296,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,209,212 - 17,291,876 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,104,796 - 17,192,048 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,184,256 - 17,265,186 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1016,569,377 - 16,655,161 (+)NCBICelera
Cytogenetic Map10q12NCBI
Sh3pxd2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540825,103,278 - 25,170,003 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540825,103,278 - 25,169,934 (-)NCBIChiLan1.0ChiLan1.0
SH3PXD2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24167,466,205 - 167,595,920 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,605,597 - 165,735,443 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,678,633 - 167,807,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,599,996 - 174,719,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,591,759 - 174,719,957 (-)Ensemblpanpan1.1panPan2
SH3PXD2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1439,854,213 - 39,950,704 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl439,854,211 - 39,949,958 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha439,798,319 - 39,901,983 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0440,225,207 - 40,326,590 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,225,205 - 40,322,450 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,040,426 - 40,144,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,229,786 - 40,330,413 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0440,740,272 - 40,843,969 (+)NCBIUU_Cfam_GSD_1.0
Sh3pxd2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,204,073 - 94,256,232 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366092,926,771 - 2,978,914 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366092,934,814 - 2,975,111 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3PXD2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1651,733,135 - 51,858,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11651,733,170 - 51,858,774 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,105,843 - 56,228,717 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SH3PXD2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,498,389 - 74,613,296 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2374,498,381 - 74,613,123 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660344,001,985 - 4,124,148 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3pxd2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473317,577,336 - 17,688,155 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473317,577,262 - 17,686,212 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh3pxd2b
3259 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1977
Count of miRNA genes:747
Interacting mature miRNAs:986
Transcripts:ENSMUST00000038753, ENSMUST00000138771
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300607Tnbs2_mtri-nitrobenzene sulfonic acid susceptible 2 (mouse)Not determined112489805235126680Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
25394552Skmw69_mskeletal muscle weight 69, TA (mouse)112969902932329535Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
25394550Skmw71_mskeletal muscle weight 71, gastroc (mouse)113127543232745567Mouse
25394551Skmw70_mskeletal muscle weight 70, EDL (mouse)113132273732594975Mouse
25394558Skmw72_mskeletal muscle weight 72, soleus (mouse)113132943032785551Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse

Markers in Region
20.MMHAP35FLG2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381132,359,423 - 32,359,603UniSTSGRCm38
MGSCv371132,259,423 - 32,259,603UniSTSGRCm37
Celera1134,776,712 - 34,776,890UniSTS
Cytogenetic Map11A4UniSTS
Whitehead_YAC11 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_177364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB430861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY197208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000038753   ⟹   ENSMUSP00000044276
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,297,820 - 32,378,173 (+)Ensembl
GRCm38.p6 Ensembl1132,347,820 - 32,428,173 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,297,840 - 32,340,300 (+)Ensembl
GRCm38.p6 Ensembl1132,347,840 - 32,390,300 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239041   ⟹   ENSMUSP00000158896
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,297,820 - 32,378,173 (+)Ensembl
GRCm38.p6 Ensembl1132,347,820 - 32,428,173 (+)Ensembl
RefSeq Acc Id: NM_177364   ⟹   NP_796338
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,297,840 - 32,378,189 (+)NCBI
GRCm381132,347,840 - 32,428,189 (+)NCBI
MGSCv371132,247,811 - 32,328,183 (+)RGD
Celera1134,765,291 - 34,845,918 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514712   ⟹   XP_006514775
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,297,777 - 32,378,036 (+)NCBI
GRCm381132,347,773 - 32,428,036 (+)NCBI
Sequence:
RefSeq Acc Id: NP_796338   ⟸   NM_177364
- UniProtKB: Q3TB89 (UniProtKB/Swiss-Prot),   Q1LZM5 (UniProtKB/Swiss-Prot),   Q1LZL8 (UniProtKB/Swiss-Prot),   B6F0V1 (UniProtKB/Swiss-Prot),   Q8BIC6 (UniProtKB/Swiss-Prot),   A2AAY5 (UniProtKB/Swiss-Prot),   B9EJ37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006514775   ⟸   XM_006514712
- Peptide Label: isoform X1
- UniProtKB: A0A5F8MPP7 (UniProtKB/TrEMBL),   B9EJ37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000158896   ⟸   ENSMUST00000239041
RefSeq Acc Id: ENSMUSP00000044276   ⟸   ENSMUST00000038753
Protein Domains
PX   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AAY5-F1-model_v2 AlphaFold A2AAY5 1-908 view protein structure

Promoters
RGD ID:6822091
Promoter ID:MM_KWN:6884
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   MEF_B4
Transcripts:NM_177364,   UC007IJO.1,   UC007IJP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361132,247,571 - 32,248,071 (+)MPROMDB
RGD ID:8674240
Promoter ID:EPDNEW_M15151
Type:initiation region
Name:Sh3pxd2b_1
Description:Mus musculus SH3 and PX domains 2B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381132,347,840 - 32,347,900EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442062 AgrOrtholog
Ensembl Genes ENSMUSG00000040711 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000038753 ENTREZGENE
  ENSMUST00000038753.6 UniProtKB/Swiss-Prot
  ENSMUST00000239041 ENTREZGENE
  ENSMUST00000239041.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3PXD2_PX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3PXD2B_SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3PXD2B_SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3PXD2B_SH3_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3PXD2B_SH3_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:268396 UniProtKB/Swiss-Prot
MGD MGI:2442062 ENTREZGENE
NCBI Gene 268396 ENTREZGENE
PANTHER SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 MULTIPLE DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sh3pxd2b PhenoGen
PROSITE PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5F8MPP7 ENTREZGENE, UniProtKB/TrEMBL
  A2AAY5 ENTREZGENE
  B6F0V1 ENTREZGENE
  B9EJ37 ENTREZGENE, UniProtKB/TrEMBL
  Q1LZL8 ENTREZGENE
  Q1LZM5 ENTREZGENE
  Q3TB89 ENTREZGENE
  Q3TDV5_MOUSE UniProtKB/TrEMBL
  Q571L4_MOUSE UniProtKB/TrEMBL
  Q5DTZ1_MOUSE UniProtKB/TrEMBL
  Q8BIC6 ENTREZGENE
  Q8BY34_MOUSE UniProtKB/TrEMBL
  SPD2B_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary B6F0V1 UniProtKB/Swiss-Prot
  Q1LZL8 UniProtKB/Swiss-Prot
  Q1LZM5 UniProtKB/Swiss-Prot
  Q3TB89 UniProtKB/Swiss-Prot
  Q8BIC6 UniProtKB/Swiss-Prot