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Gene: Grm1 (glutamate receptor, metabotropic 1) Mus musculus
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Symbol: Grm1
Name: glutamate receptor, metabotropic 1
Description: Exhibits G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Involved in several processes, including cellular response to electrical stimulus; positive regulation of MAP kinase activity; and regulation of sensory perception of pain. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density. Is expressed in several structures, including appendicular skeleton; eye; nervous system; testis; and tongue. Used to study autosomal recessive spinocerebellar ataxia 13; skin melanoma; and uveal melanoma. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Orthologous to human GRM1 (glutamate metabotropic receptor 1); PARTICIPATES IN glutamate signaling pathway; Huntington's disease pathway; long term depression; INTERACTS WITH (S)-amphetamine; 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930455H15Rik; ENSMUSG00000075319; G protein coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member A; Gm10828; Gprc1a; metabotropic glutamate receptor 1; MGC90744; mGluR1; nmf373; predicted gene 10828; rcw; wobl
Orthologs:
Homo sapiens (human) : GRM1 (glutamate metabotropic receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grm1 (glutamate metabotropic receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm1 (glutamate metabotropic receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM1 (glutamate metabotropic receptor 1)
Canis lupus familiaris (dog) : GRM1 (glutamate metabotropic receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm1 (glutamate metabotropic receptor 1)
Sus scrofa (pig) : GRM1 (glutamate metabotropic receptor 1)
Chlorocebus sabaeus (African green monkey) : GRM1 (glutamate metabotropic receptor 1)
Heterocephalus glaber (naked mole-rat) : Grm1 (glutamate metabotropic receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1010,686,059 - 11,082,356 (-)EnsemblGRCm38mm10GRCm38
GRCm381010,686,059 - 11,082,382 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371010,408,551 - 10,802,129 (-)NCBIGRCm37mm9NCBIm37
MGSCv361010,378,943 - 10,772,546 (-)NCBImm8
Celera1010,578,372 - 10,975,041 (-)NCBICelera
Cytogenetic Map10A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
 
More on Grm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731957
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.