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Gene: Map2k5 (mitogen-activated protein kinase kinase 5) Mus musculus
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Symbol: Map2k5
Name: mitogen-activated protein kinase kinase 5
RGD ID: 62183
Description: Predicted to have ATP binding activity; MAP kinase kinase activity; and protein serine/threonine kinase activity. Involved in MAPK cascade and heart development. Localizes to spindle. Is expressed in early conceptus; oocyte; and telencephalon. Orthologous to human MAP2K5 (mitogen-activated protein kinase kinase 5); PARTICIPATES IN altered Erk5 MAPK signaling pathway; Erk5 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI324775; AI428457; dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; Prkmk5
Orthologs:
Homo sapiens (human) : MAP2K5 (mitogen-activated protein kinase kinase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Map2k5 (mitogen activated protein kinase kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k5 (mitogen-activated protein kinase kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Canis lupus familiaris (dog) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k5 (mitogen-activated protein kinase kinase 5)
Sus scrofa (pig) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Chlorocebus sabaeus (African green monkey) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Heterocephalus glaber (naked mole-rat) : Map2k5 (mitogen-activated protein kinase kinase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl963,163,768 - 63,377,902 (-)EnsemblGRCm38mm10GRCm38
GRCm38963,163,768 - 63,381,682 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37963,011,577 - 63,225,659 (-)NCBIGRCm37mm9NCBIm37
MGSCv36962,961,776 - 63,175,858 (-)NCBImm8
Celera960,383,063 - 60,597,534 (-)NCBICelera
Cytogenetic Map9B-CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Map2k5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62183
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.