Drd2 (dopamine receptor D2) - Rat Genome Database

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Gene: Drd2 (dopamine receptor D2) Mus musculus
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Symbol: Drd2
Name: dopamine receptor D2
RGD ID: 10486
MGI Page MGI
Description: Enables G protein-coupled receptor activity; dopamine binding activity; and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in hyaloid vascular plexus regression; negative regulation of innate immune response; and regulation of neurotransmitter transport. Acts upstream of or within several processes, including modulation of chemical synaptic transmission; nervous system development; and regulation of ion transport. Located in several cellular components, including GABA-ergic synapse; dendrite; and dopaminergic synapse. Is integral component of presynaptic membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study Parkinson's disease and primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; mental depression; migraine with aura; obesity; and type 2 diabetes mellitus. Orthologous to human DRD2 (dopamine receptor D2); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; dopamine signaling pathway; dopamine signaling pathway via D2 family of receptors; INTERACTS WITH (+)-pilocarpine; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D(2) dopamine receptor; D2; D2 receptor; D2R; dopamine D2 receptor; dopamine receptor 2; Drd-; Drd-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39949,251,633 - 49,319,477 (+)NCBIGRCm39mm39
GRCm39 Ensembl949,251,927 - 49,319,477 (+)Ensembl
GRCm38949,340,360 - 49,408,177 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl949,340,627 - 49,408,177 (+)EnsemblGRCm38mm10GRCm38
MGSCv37949,148,767 - 49,215,319 (+)NCBIGRCm37mm9NCBIm37
MGSCv36949,092,857 - 49,160,407 (+)NCBImm8
Celera946,638,220 - 46,705,025 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
alcohol use disorder  (IEA)
Alcoholic Intoxication  (ISO)
Alzheimer's disease  (ISO)
amphetamine abuse  (ISO)
anxiety disorder  (ISO)
attention deficit hyperactivity disorder  (ISO)
basal ganglia disease  (ISO)
Binge-Eating Disorder  (ISO)
Bradycardia  (ISO)
Brain Concussion  (ISO)
Brain Injuries  (ISO)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
Catalepsy  (ISO)
cocaine dependence  (ISO)
Cocaine-Related Disorders  (ISO)
cognitive disorder  (ISO)
dementia  (ISO)
Developmental Disabilities  (ISO)
drug psychosis  (ISO)
Drug-Induced Dyskinesia  (ISO)
Dyskinesias  (ISO)
dystonia  (ISO)
end stage renal disease  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Gilles de la Tourette syndrome  (ISO)
heroin dependence  (ISO)
Huntington's disease  (IEP,IGI)
Hyperkinesis  (ISO)
hyperprolactinemia  (ISO)
hypertension  (ISO)
Hypotension  (ISO)
impulse control disorder  (ISO)
intellectual disability  (ISO)
language disorder  (ISO)
Memory Disorders  (ISO)
mental depression  (ISO)
migraine with aura  (ISO)
morphine dependence  (ISO)
movement disease  (ISO)
myoclonic dystonia 11  (ISO)
Neuralgia  (ISO)
obesity  (ISO)
ovarian hyperstimulation syndrome  (ISO)
Pain  (ISO)
Parkinson's disease  (IEA,ISO)
Parkinsonism  (ISO)
Pituitary Neoplasms  (ISO)
primary hyperaldosteronism  (IEA)
schizophrenia  (ISO)
substance-related disorder  (ISO)
Tachycardia  (ISO)
Tobacco Use Disorder  (ISO)
toxic encephalopathy  (ISO)
type 2 diabetes mellitus  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
withdrawal disorder  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-butaclamol  (ISO)
(+)-pilocarpine  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin  (ISO)
(R)-lipoic acid  (ISO)
(R)-noradrenaline  (ISO)
(R,R)-tramadol  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-bromopropane  (ISO)
1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP)
2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine  (ISO)
3',5'-cyclic AMP  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide  (EXP,ISO)
3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide  (ISO)
4-hydroxynon-2-enal  (ISO)
6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide  (ISO)
8-(3-chlorostyryl)caffeine  (EXP)
acamprosate  (ISO)
aflatoxin B1  (ISO)
albiflorin  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amisulpride  (ISO)
amitraz  (EXP)
amlodipine  (EXP)
ammonium chloride  (ISO)
amoxapine  (EXP)
amphetamine  (EXP,ISO)
antimycin A  (ISO)
apigenin  (ISO)
apomorphine  (EXP,ISO)
aprindine  (EXP)
aripiprazole  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
atrazine  (ISO)
azoxystrobin  (ISO)
Bardoxolone methyl  (ISO)
barium(0)  (ISO)
Bay-K-8644  (ISO)
benserazide  (ISO)
benzamides  (ISO)
benzimidazoles  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromocriptine  (EXP,ISO)
Bromperidol  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
caffeine  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP)
cannabigerol  (EXP)
carbamazepine  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
cinnarizine  (EXP,ISO)
clomipramine  (ISO)
clozapine  (EXP,ISO)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
curcumin  (ISO)
cyanazine  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (EXP)
cyhalothrin  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
Deguelin  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichlorvos  (ISO)
diltiazem  (EXP)
dizocilpine  (ISO)
dizocilpine maleate  (EXP)
domperidone  (EXP,ISO)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
ethanol  (EXP,ISO)
felbamate  (ISO)
fenpyroximate  (ISO)
flunarizine  (EXP,ISO)
fluoxetine  (ISO)
fluphenazine  (ISO)
formaldehyde  (EXP)
furan  (ISO)
gadolinium atom  (ISO)
gamma-hexachlorocyclohexane  (ISO)
haloperidol  (EXP,ISO)
heroin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
kainic acid  (EXP)
ketamine  (ISO)
lamotrigine  (ISO)
lanthanum atom  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipoic acid  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
loxapine  (ISO)
lurasidone hydrochloride  (ISO)
lysergic acid diethylamide  (ISO)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
manidipine  (EXP)
melatonin  (EXP,ISO)
melevodopa  (ISO)
melittin  (ISO)
mephedrone  (ISO)
methadone  (ISO)
methamphetamine  (EXP,ISO)
methylmercury chloride  (EXP)
methylphenidate  (EXP,ISO)
metoclopramide  (EXP,ISO)
mirtazapine  (ISO)
morphine  (EXP,ISO)
N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nafadotride  (ISO)
naltrexone  (ISO)
nicotine  (ISO)
nifedipine  (ISO)
nimodipine  (ISO)
nitrogen dioxide  (ISO)
Nonylphenol  (ISO)
olanzapine  (EXP,ISO)
oxidopamine  (ISO)
oxybutynin  (EXP)
Oxypertine  (ISO)
paliperidone palmitate  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pentetrazol  (EXP)
pentobarbital  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
pergolide  (ISO)
phencyclidine  (EXP,ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
piperazines  (ISO)
piperidines  (ISO)
pramipexole  (ISO)
pregabalin  (EXP)
propamocarb  (EXP)
Propiverine  (EXP)
pyridines  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
quetiapine fumarate  (ISO)
quinolinic acid  (ISO)
quinpirole  (EXP,ISO)
reserpine  (EXP,ISO)
risperidone  (ISO)
ropinirole  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
serotonin  (ISO)
simvastatin  (ISO)
SKF 38393  (EXP,ISO)
sodium arsenite  (ISO)
spiperone  (EXP,ISO)
sulpiride  (EXP,ISO)
tacrolimus hydrate  (ISO)
Tautomycin  (ISO)
tebufenpyrad  (ISO)
tetrachloromethane  (EXP,ISO)
tetrahydropalmatine  (ISO)
thifluzamide  (ISO)
Tiapamil  (EXP,ISO)
topiramate  (EXP)
tramadol  (ISO)
trichostatin A  (EXP)
valproic acid  (ISO)
verapamil  (EXP)
vorinostat  (ISO)
zinc acetate  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acid secretion  (ISO)
activation of protein kinase activity  (ISO)
adenohypophysis development  (IMP)
adenylate cyclase-activating adrenergic receptor signaling pathway  (IBA)
adenylate cyclase-inhibiting dopamine receptor signaling pathway  (IBA,IDA,IGI,IMP,ISO)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (ISO)
adult behavior  (IMP)
adult walking behavior  (IMP)
arachidonic acid secretion  (ISO)
associative learning  (IMP)
auditory behavior  (ISO)
autophagy  (ISO)
axonogenesis  (IMP)
behavioral response to cocaine  (IMP)
behavioral response to ethanol  (IMP)
branching morphogenesis of a nerve  (IMP)
cerebral cortex GABAergic interneuron migration  (IMP)
circadian regulation of gene expression  (IMP)
dopamine metabolic process  (IMP)
dopamine receptor signaling pathway  (IGI,ISO)
drinking behavior  (ISO)
feeding behavior  (IGI)
forebrain development  (ISO)
G protein-coupled receptor internalization  (ISO)
G protein-coupled receptor signaling pathway  (IDA)
grooming behavior  (IMP)
hyaloid vascular plexus regression  (IMP)
intracellular signal transduction  (ISO)
locomotory behavior  (IGI,IMP,ISO)
long-term memory  (ISO)
modulation of chemical synaptic transmission  (IMP)
negative regulation of adenylate cyclase activity  (IBA,ISO)
negative regulation of blood pressure  (IMP)
negative regulation of cell death  (ISO)
negative regulation of cell migration  (IMP)
negative regulation of cell population proliferation  (IGI,IMP)
negative regulation of circadian sleep/wake cycle, sleep  (ISO)
negative regulation of cytosolic calcium ion concentration  (IBA,ISO)
negative regulation of dopamine receptor signaling pathway  (IGI,IMP)
negative regulation of dopamine secretion  (ISO)
negative regulation of innate immune response  (IMP)
negative regulation of insulin secretion  (ISO)
negative regulation of protein kinase B signaling  (IMP)
negative regulation of protein phosphorylation  (ISO)
negative regulation of protein secretion  (ISO)
negative regulation of synaptic transmission  (ISO)
negative regulation of synaptic transmission, glutamatergic  (IBA,IMP)
negative regulation of voltage-gated calcium channel activity  (IBA,ISO)
nervous system process involved in regulation of systemic arterial blood pressure  (IMP)
neuron-neuron synaptic transmission  (IMP)
orbitofrontal cortex development  (ISO)
peristalsis  (IGI,IMP)
phospholipase C-activating dopamine receptor signaling pathway  (IBA,IDA,IGI,ISO)
pigmentation  (IMP)
positive regulation of cytokinesis  (ISO)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (IBA,ISO)
positive regulation of dopamine uptake involved in synaptic transmission  (IMP)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of G protein-coupled receptor signaling pathway  (ISO)
positive regulation of glial cell-derived neurotrophic factor production  (ISO)
positive regulation of growth hormone secretion  (IMP)
positive regulation of long-term synaptic potentiation  (ISO)
positive regulation of multicellular organism growth  (IMP)
positive regulation of neuroblast proliferation  (IDA)
positive regulation of neurogenesis  (ISO)
positive regulation of receptor internalization  (ISO)
positive regulation of renal sodium excretion  (IMP)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of urine volume  (IMP)
postsynaptic modulation of chemical synaptic transmission  (ISO)
prepulse inhibition  (IMP)
protein localization  (IMP)
regulation of dopamine secretion  (IBA,IMP)
regulation of dopamine uptake involved in synaptic transmission  (IMP)
regulation of heart rate  (IMP)
regulation of locomotion involved in locomotory behavior  (ISO)
regulation of long-term neuronal synaptic plasticity  (IMP)
regulation of MAPK cascade  (ISO)
regulation of neurotransmitter uptake  (EXP,IDA,IMP)
regulation of phosphoprotein phosphatase activity  (ISO)
regulation of potassium ion transport  (IBA,IMP,ISO)
regulation of sodium ion transport  (IMP)
regulation of synapse structural plasticity  (ISO)
regulation of synaptic transmission, GABAergic  (IGI,IMP)
regulation of synaptic vesicle exocytosis  (EXP,IDA,IMP)
release of sequestered calcium ion into cytosol  (ISO)
response to amphetamine  (IGI,IMP,ISO)
response to axon injury  (ISO)
response to cocaine  (IDA,IMP)
response to ethanol  (ISO)
response to histamine  (ISO)
response to hypoxia  (ISO)
response to inactivity  (ISO)
response to iron ion  (ISO)
response to light stimulus  (IMP)
response to morphine  (IMP)
response to nicotine  (ISO)
response to toxic substance  (ISO)
response to xenobiotic stimulus  (IDA,IMP,ISO)
sensory perception of smell  (IMP)
signal transduction  (IEA)
startle response  (IMP)
striatum development  (ISO)
synapse assembly  (ISO)
temperature homeostasis  (IMP)
visual learning  (IMP)
Wnt signaling pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adenohypophysis morphology  (IAGP)
abnormal adrenal gland zona fasciculata morphology  (IAGP)
abnormal adrenal gland zona reticularis morphology  (IAGP)
abnormal astrocyte physiology  (IAGP)
abnormal behavior  (IAGP)
abnormal behavioral response to xenobiotic  (IAGP)
abnormal brain development  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal defecation  (IAGP)
abnormal digestive system development  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal dopamine level  (IAGP)
abnormal duodenum morphology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal emotion/affect behavior  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal estrus  (IAGP)
abnormal excitatory postsynaptic currents  (IAGP)
abnormal GABAergic neuron morphology  (IAGP)
abnormal gait  (IAGP)
abnormal hormone level  (IAGP)
abnormal hypothalamus physiology  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal intestinal absorption  (IAGP)
abnormal intestinal smooth muscle morphology  (IAGP)
abnormal intestinal transit time  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal large intestinal transit time  (IAGP)
abnormal latent inhibition of conditioning behavior  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locomotor behavior  (IAGP)
abnormal melanotroph morphology  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal operant conditioning behavior  (IAGP)
abnormal pituitary gland morphology  (IAGP)
abnormal pituitary gland physiology  (IAGP)
abnormal prepulse inhibition  (IAGP)
abnormal response to novel odor  (IAGP)
abnormal single cell response  (IAGP)
abnormal social/conspecific interaction  (IAGP)
abnormal stomach morphology  (IAGP)
abnormal synaptic dopamine release  (IAGP)
abnormal systemic arterial blood pressure  (IAGP)
abnormal vocalization  (IAGP)
absent gastric milk in neonates  (IAGP)
absent long term depression  (IAGP)
adenohypophysis hyperplasia  (IAGP)
adenohypophysis hypertrophy  (IAGP)
adenohypophysis peliosis  (IAGP)
adrenal cortical hyperplasia  (IAGP)
akinesia  (IAGP)
alcohol aversion  (IAGP)
aphagia  (IAGP)
astrocytosis  (IAGP)
ataxia  (IAGP)
bradykinesia  (IAGP)
catalepsy  (IAGP)
darkened coat color  (IAGP)
decreased aggression towards males  (IAGP)
decreased alcohol consumption  (IAGP)
decreased anxiety-related response  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased circulating estrogen level  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased dopamine level  (IAGP)
decreased dopaminergic neuron number  (IAGP)
decreased fluid intake  (IAGP)
decreased food intake  (IAGP)
decreased gonadotroph cell number  (IAGP)
decreased growth hormone level  (IAGP)
decreased inguinal fat pad weight  (IAGP)
decreased lactotroph cell size  (IAGP)
decreased liver weight  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased pulmonary ventilation  (IAGP)
decreased response to stress-induced hyperthermia  (IAGP)
decreased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
decreased somatotroph cell number  (IAGP)
decreased spleen weight  (IAGP)
decreased startle reflex  (IAGP)
decreased urine major urinary protein level  (IAGP)
decreased vertical activity  (IAGP)
enhanced behavioral response to anesthetic  (IAGP)
enhanced behavioral response to cocaine  (IAGP)
enhanced behavioral response to xenobiotic  (IAGP)
enlarged adrenocortical cells  (IAGP)
enlarged pituitary gland  (IAGP)
enlarged pituitary intermediate lobe  (IAGP)
gastrointestinal hemorrhage  (IAGP)
hunched posture  (IAGP)
hyperactivity  (IAGP)
hyperpigmentation  (IAGP)
hypersecretion of corticosterone  (IAGP)
hypoactivity  (IAGP)
impaired behavioral response to addictive substance  (IAGP)
impaired behavioral response to alcohol  (IAGP)
impaired behavioral response to anesthetic  (IAGP)
impaired behavioral response to cocaine  (IAGP)
impaired behavioral response to xenobiotic  (IAGP)
impaired conditioned place preference behavior  (IAGP)
impaired coordination  (IAGP)
increased body weight  (IAGP)
increased circulating adrenocorticotropin level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating pituitary hormone level  (IAGP)
increased circulating prolactin level  (IAGP)
increased defecation amount  (IAGP)
increased dopamine level  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased growth hormone level  (IAGP)
increased heart rate  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased lactotroph cell number  (IAGP)
increased mean systemic arterial blood pressure  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased pituitary adenoma incidence  (IAGP)
increased pituitary gland weight  (IAGP)
increased pituitary hormone level  (IAGP)
increased pulmonary respiratory rate  (IAGP)
increased pulmonary ventilation  (IAGP)
increased susceptibility to dopaminergic neuron neurotoxicity  (IAGP)
increased susceptibility to neuronal excitotoxicity  (IAGP)
increased susceptibility to pharmacologically induced seizures  (IAGP)
increased systemic arterial diastolic blood pressure  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased thyrotroph cell number  (IAGP)
increased tidal volume  (IAGP)
increased urine sodium level  (IAGP)
increased vertical activity  (IAGP)
induced hyperactivity  (IAGP)
intestinal ulcer  (IAGP)
limp posture  (IAGP)
microgliosis  (IAGP)
no abnormal phenotype detected  (IEA)
pituitary gland hyperplasia  (IAGP)
pituitary intermediate lobe hyperplasia  (IAGP)
polyuria  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prolonged diestrus  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
short femur  (IAGP)
short uterine horn  (IAGP)
slow postnatal weight gain  (IAGP)
small intestinal inflammation  (IAGP)
small ovary  (IAGP)
small testis  (IAGP)
unidirectional circling  (IAGP)
uterus adenomyosis  (IAGP)
uterus cysts  (IAGP)
uterus hyperplasia  (IAGP)
References

References - curated
1. Ariano MA, etal., J Neurosci Res. 2002 Jun 15;68(6):716-29.
2. Baik JH, etal., Nature 1995 Oct 5;377(6548):424-8.
3. Barbanti P, etal., Mech Ageing Dev. 2000 Dec 1;120(1-3):65-75.
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Additional References at PubMed
PMID:1861151   PMID:1980140   PMID:1991517   PMID:2137198   PMID:2138567   PMID:2531656   PMID:7527545   PMID:7549459   PMID:7609622   PMID:7706278   PMID:7925842   PMID:7978106  
PMID:8001143   PMID:8247548   PMID:8288218   PMID:8294904   PMID:8313980   PMID:8441607   PMID:8530376   PMID:8601467   PMID:8649810   PMID:8661102   PMID:8662838   PMID:8672141  
PMID:8748389   PMID:8827514   PMID:8836575   PMID:8889548   PMID:9022080   PMID:9140068   PMID:9169514   PMID:9191109   PMID:9247267   PMID:9247268   PMID:9252189   PMID:9354330  
PMID:9547254   PMID:9717839   PMID:9726281   PMID:9829800   PMID:9876181   PMID:9886065   PMID:9988094   PMID:10051229   PMID:10103122   PMID:10196569   PMID:10341260   PMID:10391470  
PMID:10393115   PMID:10471093   PMID:10506202   PMID:10537166   PMID:10591541   PMID:10598210   PMID:10698004   PMID:10765558   PMID:10811014   PMID:10828532   PMID:10908627   PMID:10934242  
PMID:10956362   PMID:10974427   PMID:10998124   PMID:11015197   PMID:11039723   PMID:11054572   PMID:11054779   PMID:11060228   PMID:11069937   PMID:11069974   PMID:11089973   PMID:11105945  
PMID:11124115   PMID:11150348   PMID:11158626   PMID:11160501   PMID:11166059   PMID:11172060   PMID:11264672   PMID:11303741   PMID:11423089   PMID:11438590   PMID:11557166   PMID:11566895  
PMID:11567069   PMID:11717346   PMID:11860278   PMID:11864730   PMID:11897683   PMID:11923462   PMID:11943831   PMID:12084937   PMID:12097513   PMID:12133472   PMID:12175868   PMID:12182883  
PMID:12185400   PMID:12223546   PMID:12223553   PMID:12297539   PMID:12370275   PMID:12391292   PMID:12397111   PMID:12417685   PMID:12431847   PMID:12446580   PMID:12466851   PMID:12476322  
PMID:12477932   PMID:12543998   PMID:12637032   PMID:12650980   PMID:12665504   PMID:12724834   PMID:12777963   PMID:12837020   PMID:12867509   PMID:12930822   PMID:12943989   PMID:12949782  
PMID:12972179   PMID:14534241   PMID:14553965   PMID:14681479   PMID:14684868   PMID:14712229   PMID:14744041   PMID:14960355   PMID:14973278   PMID:14999024   PMID:15016423   PMID:15061865  
PMID:15080900   PMID:15197646   PMID:15272078   PMID:15276241   PMID:15489038   PMID:15537671   PMID:15653180   PMID:15689540   PMID:15716360   PMID:15721235   PMID:15817666   PMID:15996639  
PMID:16012197   PMID:16051151   PMID:16077018   PMID:16123747   PMID:16125819   PMID:16136297   PMID:16280580   PMID:16336634   PMID:16476524   PMID:16476668   PMID:16482403   PMID:16525059  
PMID:16602821   PMID:16606840   PMID:16633898   PMID:16641236   PMID:16715079   PMID:16715495   PMID:16765459   PMID:16865686   PMID:16962565   PMID:17026527   PMID:17194762   PMID:17207476  
PMID:17222350   PMID:17251429   PMID:17324452   PMID:17409246   PMID:17426149   PMID:17426594   PMID:17460091   PMID:17509542   PMID:17535813   PMID:17543035   PMID:17599952   PMID:17634367  
PMID:17673562   PMID:17706924   PMID:17712281   PMID:17784836   PMID:17848635   PMID:17936519   PMID:17942719   PMID:17984145   PMID:18083900   PMID:18206662   PMID:18214604   PMID:18279319  
PMID:18340382   PMID:18346199   PMID:18363853   PMID:18363855   PMID:18382674   PMID:18410503   PMID:18486343   PMID:18635969   PMID:18644244   PMID:18644790   PMID:18671743   PMID:18716204  
PMID:18800071   PMID:18832466   PMID:18835570   PMID:18973573   PMID:18997437   PMID:19012810   PMID:19017537   PMID:19030180   PMID:19117916   PMID:19144721   PMID:19148742   PMID:19176830  
PMID:19187797   PMID:19228458   PMID:19274089   PMID:19302158   PMID:19309759   PMID:19401217   PMID:19508875   PMID:19520364   PMID:19570576   PMID:19667187   PMID:19702084   PMID:19720621  
PMID:19741115   PMID:19747903   PMID:19765599   PMID:19840852   PMID:19842069   PMID:19853839   PMID:19887632   PMID:19906957   PMID:19940170   PMID:19948956   PMID:20016831   PMID:20018672  
PMID:20038975   PMID:20049328   PMID:20080963   PMID:20092552   PMID:20147524   PMID:20175225   PMID:20227500   PMID:20335474   PMID:20336622   PMID:20451634   PMID:20463460   PMID:20477910  
PMID:20505090   PMID:20543951   PMID:20546314   PMID:20551902   PMID:20576036   PMID:20601948   PMID:20625330   PMID:20652026   PMID:20730802   PMID:20805489   PMID:20807772   PMID:20846243  
PMID:20958329   PMID:20975260   PMID:20980993   PMID:21128941   PMID:21192082   PMID:21195752   PMID:21196914   PMID:21209197   PMID:21233214   PMID:21233215   PMID:21303698   PMID:21454669  
PMID:21521749   PMID:21603181   PMID:21622564   PMID:21633887   PMID:21730148   PMID:21743470   PMID:21803530   PMID:21821099   PMID:21873635   PMID:21912682   PMID:21931745   PMID:21945484  
PMID:21982372   PMID:22003095   PMID:22017419   PMID:22033896   PMID:22034973   PMID:22041981   PMID:22069189   PMID:22082989   PMID:22168837   PMID:22219295   PMID:22308372   PMID:22396414  
PMID:22419037   PMID:22492051   PMID:22529362   PMID:22537018   PMID:22586226   PMID:22592925   PMID:22639229   PMID:22719934   PMID:22745501   PMID:22748019   PMID:22764222   PMID:22820144  
PMID:22884478   PMID:23000618   PMID:23015686   PMID:23070814   PMID:23090999   PMID:23188793   PMID:23242137   PMID:23248274   PMID:23291158   PMID:23305992   PMID:23314019   PMID:23319622  
PMID:23422792   PMID:23458603   PMID:23481387   PMID:23521753   PMID:23533084   PMID:23536095   PMID:23597509   PMID:23608643   PMID:23616563   PMID:23637801   PMID:23675505   PMID:23711983  
PMID:23753418   PMID:23811070   PMID:23843993   PMID:23863478   PMID:23876451   PMID:23884939   PMID:23954414   PMID:23954803   PMID:23955337   PMID:24008346   PMID:24024122   PMID:24120383  
PMID:24351932   PMID:24391960   PMID:24411738   PMID:24424036   PMID:24434772   PMID:24496082   PMID:24529758   PMID:24619418   PMID:24737889   PMID:24742619   PMID:24747614   PMID:24748435  
PMID:24753432   PMID:24790185   PMID:24830745   PMID:24872568   PMID:24904170   PMID:24952961   PMID:25024286   PMID:25076876   PMID:25097246   PMID:25217530   PMID:25281921   PMID:25393815  
PMID:25393953   PMID:25511804   PMID:25545383   PMID:25545461   PMID:25547712   PMID:25556545   PMID:25560761   PMID:25578797   PMID:25594175   PMID:25637489   PMID:25675529   PMID:25729269  
PMID:25781028   PMID:25865831   PMID:25964346   PMID:26053317   PMID:26104289   PMID:26256420   PMID:26281715   PMID:26290374   PMID:26305972   PMID:26308580   PMID:26359228   PMID:26442961  
PMID:26459714   PMID:26483399   PMID:26484605   PMID:26511239   PMID:26560700   PMID:26585834   PMID:26693483   PMID:26831103   PMID:26896754   PMID:26992232   PMID:27035941   PMID:27036891  
PMID:27079169   PMID:27181061   PMID:27196975   PMID:27246266   PMID:27317196   PMID:27373926   PMID:27387649   PMID:27405468   PMID:27452460   PMID:27460988   PMID:27508444   PMID:27671625  
PMID:27678414   PMID:27802964   PMID:27867937   PMID:27911814   PMID:28041956   PMID:28108253   PMID:28115522   PMID:28124114   PMID:28128287   PMID:28145402   PMID:28152577   PMID:28154160  
PMID:28410269   PMID:28429261   PMID:28433741   PMID:28473642   PMID:28531297   PMID:28582422   PMID:28583861   PMID:28663556   PMID:28698578   PMID:28830816   PMID:28860974   PMID:28911199  
PMID:28912160   PMID:28912499   PMID:29030431   PMID:29053217   PMID:29071300   PMID:29154756   PMID:29183706   PMID:29255027   PMID:29429048   PMID:29434188   PMID:29472382   PMID:29527566  
PMID:29531031   PMID:29595454   PMID:29603470   PMID:29695836   PMID:29704613   PMID:29769195   PMID:29786071   PMID:29891954   PMID:29949769   PMID:29967281   PMID:30026489   PMID:30082890  
PMID:30111840   PMID:30120413   PMID:30208054   PMID:30208314   PMID:30254156   PMID:30258218   PMID:30295716   PMID:30297767   PMID:30348762   PMID:30362616   PMID:30413696   PMID:30552094  
PMID:30622165   PMID:30626912   PMID:30695556   PMID:30718509   PMID:30775693   PMID:30936473   PMID:31060803   PMID:31326375   PMID:31371425   PMID:31449520   PMID:31491374   PMID:31538542  
PMID:31665630   PMID:31704949   PMID:31727925   PMID:31809732   PMID:32034128   PMID:32041188   PMID:32052901   PMID:32060901   PMID:32071304   PMID:32142670   PMID:32165725   PMID:32170006  
PMID:32175760   PMID:32320647   PMID:32399024   PMID:32532293   PMID:32561725   PMID:32610120   PMID:32833186   PMID:32895370   PMID:32935231   PMID:33200438   PMID:33214315   PMID:33339892  
PMID:33380525   PMID:33476687   PMID:33563722   PMID:33974399  


Genomics

Comparative Map Data
Drd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39949,251,633 - 49,319,477 (+)NCBIGRCm39mm39
GRCm39 Ensembl949,251,927 - 49,319,477 (+)Ensembl
GRCm38949,340,360 - 49,408,177 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl949,340,627 - 49,408,177 (+)EnsemblGRCm38mm10GRCm38
MGSCv37949,148,767 - 49,215,319 (+)NCBIGRCm37mm9NCBIm37
MGSCv36949,092,857 - 49,160,407 (+)NCBImm8
Celera946,638,220 - 46,705,025 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.72NCBI
DRD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11113,409,605 - 113,475,691 (-)EnsemblGRCh38hg38GRCh38
GRCh3811113,409,605 - 113,475,398 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711113,280,327 - 113,346,120 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611112,785,527 - 112,851,091 (-)NCBINCBI36hg18NCBI36
Build 3411112,785,527 - 112,851,103NCBI
Celera11110,433,249 - 110,498,937 (-)NCBI
Cytogenetic Map11q23.2NCBI
HuRef11109,208,766 - 109,274,420 (-)NCBIHuRef
CHM1_111113,163,302 - 113,228,980 (-)NCBICHM1_1
Drd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2849,708,903 - 49,772,888 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl849,708,927 - 49,772,875 (+)Ensembl
Rnor_6.0853,678,777 - 53,743,643 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,678,777 - 53,743,642 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0852,298,097 - 52,363,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,641,160 - 52,707,749 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1852,660,213 - 52,726,803 (+)NCBI
Celera849,262,252 - 49,324,732 (+)NCBICelera
Cytogenetic Map8q23NCBI
Drd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,054,038 - 15,114,573 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,054,255 - 15,114,558 (-)NCBIChiLan1.0ChiLan1.0
DRD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111112,132,703 - 112,168,583 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,132,703 - 112,198,935 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011108,289,838 - 108,357,174 (-)NCBIMhudiblu_PPA_v0panPan3
DRD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,732,842 - 19,795,241 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,732,836 - 19,795,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,704,390 - 19,715,716 (+)NCBI
ROS_Cfam_1.0519,803,212 - 19,815,852 (+)NCBI
UMICH_Zoey_3.1519,865,917 - 19,877,447 (+)NCBI
UNSW_CanFamBas_1.0519,767,231 - 19,778,550 (+)NCBI
UU_Cfam_GSD_1.0519,814,856 - 19,826,385 (+)NCBI
Drd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,551,429 - 95,610,929 (-)NCBI
SpeTri2.0NW_0049366121,094,686 - 1,154,149 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,068,779 - 41,133,599 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,068,618 - 41,135,262 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2945,883,054 - 45,897,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DRD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11104,774,632 - 104,843,417 (-)NCBI
ChlSab1.1 Ensembl1104,774,180 - 104,842,736 (-)Ensembl
Vero_WHO_p1.0NW_02366604321,144,996 - 21,236,456 (+)NCBI
Drd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247848,828,589 - 8,906,617 (-)NCBI

Position Markers
X55674  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,407,815 - 49,407,934UniSTSGRCm38
MGSCv37949,215,920 - 49,216,039UniSTSGRCm37
Celera946,705,626 - 46,705,745UniSTS
Cytogenetic Map9A5.3UniSTS
Whitehead/MRC_RH9524.06UniSTS
Drd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37787,697,522 - 87,697,704UniSTSGRCm37
MGSCv37949,207,850 - 49,208,955UniSTSGRCm37
MGSCv37949,216,030 - 49,216,130UniSTSGRCm37
MGSCv37949,215,919 - 49,216,121UniSTSGRCm37
MGSCv37949,215,147 - 49,216,234UniSTSGRCm37
Celera946,697,585 - 46,698,692UniSTS
Celera946,705,625 - 46,705,826UniSTS
Celera946,704,853 - 46,705,939UniSTS
Celera946,705,736 - 46,705,835UniSTS
Celera777,957,020 - 77,957,202UniSTS
Cytogenetic Map9A5.3UniSTS
cM Map928.0UniSTS
cM Map928.0UniSTS
MARC_13871-13872:1007494510:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,402,122 - 49,403,232UniSTSGRCm38
MGSCv37949,210,227 - 49,211,337UniSTSGRCm37
Celera946,699,965 - 46,701,075UniSTS
Cytogenetic Map9A5.3UniSTS
Drd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,407,042 - 49,408,129UniSTSGRCm38
MGSCv37949,215,147 - 49,216,234UniSTSGRCm37
Celera946,704,853 - 46,705,939UniSTS
Cytogenetic Map9A5.3UniSTS
Drd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,407,814 - 49,408,016UniSTSGRCm38
MGSCv37949,215,919 - 49,216,121UniSTSGRCm37
Celera946,705,625 - 46,705,826UniSTS
Cytogenetic Map9A5.3UniSTS
cM Map928.0UniSTS
Drd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,407,925 - 49,408,025UniSTSGRCm38
MGSCv37949,216,030 - 49,216,130UniSTSGRCm37
Celera946,705,736 - 46,705,835UniSTS
Cytogenetic Map9A5.3UniSTS
cM Map928.0UniSTS
DRD2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38949,399,745 - 49,400,850UniSTSGRCm38
MGSCv37949,207,850 - 49,208,955UniSTSGRCm37
Celera946,697,585 - 46,698,692UniSTS
Cytogenetic Map9A5.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91550045549500594Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91550045549500594Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91550045549500594Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91550045549500594Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91583833149838331Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91583833149838331Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91583833149838331Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91610000050100000Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91610000050100000Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91679834550798345Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91706754451067647Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined92003211054032229Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92024206654242196Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92039490154395074Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92039490154395074Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92039490154395074Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92039490154395074Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92094144454941444Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92500000069000000Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92567618959676285Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92567618959676285Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92567618959676285Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92567618959676285Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92688512460885255Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92688512460885255Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92688512460885255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92733989761340026Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92938163163381774Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92938163163381774Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93014186664141979Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93082861764828723Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93252326366523557Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93254112166541246Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93259987266600121Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93297840266978536Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93319972567199840Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93406754473531973Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93512317869123299Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93512317869123299Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93512317869123299Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93682494749509211Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93703211050199840Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93791224471912244Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93819229172192291Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93819229172192291Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93819229172192291Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93949260173492601Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94050829851897370Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94050829874700643Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94089776474897921Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94357343177573577Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94357343177573577Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94452089278520980Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4668637365923895Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94763172657897921Mouse
13515057Adip20b_madiposity 20b (mouse)94878960853884418Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94892377482923895Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94892377482923895Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:265
Count of miRNA genes:232
Interacting mature miRNAs:255
Transcripts:ENSMUST00000075764
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000075764   ⟹   ENSMUSP00000075170
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl949,251,927 - 49,319,477 (+)Ensembl
GRCm38.p6 Ensembl949,340,627 - 49,408,177 (+)Ensembl
RefSeq Acc Id: NM_010077   ⟹   NP_034207
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39949,251,703 - 49,319,468 (+)NCBI
GRCm38949,340,403 - 49,408,168 (+)NCBI
MGSCv37949,148,767 - 49,215,319 (+)RGD
Celera946,638,220 - 46,705,025 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509996   ⟹   XP_006510059
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39949,251,633 - 49,319,477 (+)NCBI
GRCm38949,340,360 - 49,408,177 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034207   ⟸   NM_010077
- UniProtKB: P61168 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006510059   ⟸   XM_006509996
- Peptide Label: isoform X1
- UniProtKB: P61168 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000075170   ⟸   ENSMUST00000075764

Promoters
RGD ID:8669526
Promoter ID:EPDNEW_M12794
Type:single initiation site
Name:Drd2_1
Description:Mus musculus dopamine receptor D2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38949,340,590 - 49,340,650EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:94924 AgrOrtholog
Ensembl Genes ENSMUSG00000032259 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000075170 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000075764 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Dopamine_D2_rcpt UniProtKB/Swiss-Prot
  Dopamine_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report mmu:13489 UniProtKB/Swiss-Prot
MGD MGI:94924 ENTREZGENE
NCBI Gene 13489 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PharmGKB DRD2 RGD
PhenoGen Drd2 PhenoGen
PRINTS DOPAMINED2R UniProtKB/Swiss-Prot
  DOPAMINER UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
UniProt DRD2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P13953 UniProtKB/Swiss-Prot
  Q0VGH9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Drd2  dopamine receptor D2  Drd2  dopamine receptor 2  Symbol and/or name change 5135510 APPROVED