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Gene: Kcna5 (potassium voltage-gated channel, shaker-related subfamily, member 5) Mus musculus
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Symbol: Kcna5
Name: potassium voltage-gated channel, shaker-related subfamily, member 5
RGD ID: 10832
Description: Exhibits potassium channel inhibitor activity and voltage-gated potassium channel activity. Involved in several processes, including Notch signaling pathway; negative regulation of potassium ion transport; and regulation of vasoconstriction. Localizes to intercalated disc and plasma membrane. Is expressed in several structures, including gut; heart; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in familial atrial fibrillation and pulmonary hypertension. Orthologous to human KCNA5 (potassium voltage-gated channel subfamily A member 5); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KV1-5; Kv1.; Kv1.5; MGC25248; potassium voltage-gated channel subfamily A member 5; voltage-gated potassium channel subunit Kv1.5
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl6126,532,551 - 126,535,412 (-)EnsemblGRCm38mm10GRCm38
GRCm386126,532,551 - 126,535,555 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376126,482,569 - 126,485,573 (-)NCBIGRCm37mm9NCBIm37
MGSCv366126,498,172 - 126,501,031 (-)NCBImm8
Celera6128,202,194 - 128,205,198 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Kcna5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10832
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.