Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kcna5 (potassium voltage-gated channel, shaker-related subfamily, member 5) Mus musculus
Symbol: Kcna5
Name: potassium voltage-gated channel, shaker-related subfamily, member 5
RGD ID: 10832
Description: Exhibits potassium channel inhibitor activity and voltage-gated potassium channel activity. Involved in several processes, including Notch signaling pathway; negative regulation of potassium ion transport; and regulation of vasoconstriction. Localizes to intercalated disc and plasma membrane. Is expressed in several structures, including gut; heart; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in familial atrial fibrillation and pulmonary hypertension. Orthologous to human KCNA5 (potassium voltage-gated channel subfamily A member 5); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KV1-5; Kv1.; Kv1.5; MGC25248; potassium voltage-gated channel subfamily A member 5; voltage-gated potassium channel subunit Kv1.5
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl6126,532,551 - 126,535,412 (-)EnsemblGRCm38mm10GRCm38
GRCm386126,532,551 - 126,535,555 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376126,482,569 - 126,485,573 (-)NCBIGRCm37mm9NCBIm37
MGSCv366126,498,172 - 126,501,031 (-)NCBImm8
Celera6128,202,194 - 128,205,198 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcna5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10832
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.