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Gene: Krt8 (keratin 8) Mus musculus
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Symbol: Krt8
Name: keratin 8
Description: Predicted to have scaffold protein binding activity. Involved in several processes, including cell differentiation involved in embryonic placenta development; cell surface receptor signaling pathway; and hepatocyte apoptotic process. Localizes to several cellular components, including the Z disc; apicolateral plasma membrane; and sarcolemma. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and sensory organ. Orthologous to human KRT8 (keratin 8); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA960620; AL022697; AU019895; Card2; CK-8; cytokeratin 8; cytokeratin endo A; cytokeratin-8; EndoA; K8; keratin complex 2, basic, gene 8; keratin, type II cytoskeletal 8; keratin-8; Krt-2.8; Krt2-8; MGC118110; type-II keratin Kb8
Orthologs:
Homo sapiens (human) : KRT8 (keratin 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Krt8 (keratin 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Krt8 (keratin 8)
Pan paniscus (bonobo/pygmy chimpanzee) : KRT8 (keratin 8)
Canis lupus familiaris (dog) : KRT8 (keratin 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Krt8 (keratin 8)
Sus scrofa (pig) : KRT8 (keratin 8)
more info ...
Related Pseudogenes: Gm17836   Gm5355   Krt8-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3815101,996,711 - 102,004,342 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3715101,827,142 - 101,834,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615101,824,745 - 101,832,317 (-)NCBImm8
Celera15104,151,508 - 104,159,109 (-)NCBICelera
Cytogenetic Map15 F2NCBI
cM Map1557.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Krt8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735537
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.