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Gene: Krt8 (keratin 8) Mus musculus
Symbol: Krt8
Name: keratin 8
Description: Predicted to have scaffold protein binding activity. Involved in several processes, including cell differentiation involved in embryonic placenta development; cell surface receptor signaling pathway; and hepatocyte apoptotic process. Localizes to several cellular components, including the Z disc; apicolateral plasma membrane; and sarcolemma. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and sensory organ. Orthologous to human KRT8 (keratin 8); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA960620; AL022697; AU019895; Card2; CK-8; cytokeratin 8; cytokeratin endo A; cytokeratin-8; EndoA; K8; keratin complex 2, basic, gene 8; keratin, type II cytoskeletal 8; keratin-8; Krt-2.8; Krt2-8; MGC118110; type-II keratin Kb8
Homo sapiens (human) : KRT8 (keratin 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Krt8 (keratin 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Krt8 (keratin 8)
Pan paniscus (bonobo/pygmy chimpanzee) : KRT8 (keratin 8)
Canis lupus familiaris (dog) : KRT8 (keratin 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Krt8 (keratin 8)
Sus scrofa (pig) : KRT8 (keratin 8)
more info ...
Related Pseudogenes: Gm17836   Gm5355   Krt8-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3815101,996,711 - 102,004,342 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3715101,827,142 - 101,834,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615101,824,745 - 101,832,317 (-)NCBImm8
Celera15104,151,508 - 104,159,109 (-)NCBICelera
Cytogenetic Map15 F2NCBI
cM Map1557.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Krt8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735537
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.