Polr2g (polymerase (RNA) II (DNA directed) polypeptide G) - Rat Genome Database

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Gene: Polr2g (polymerase (RNA) II (DNA directed) polypeptide G) Mus musculus
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Symbol: Polr2g
Name: polymerase (RNA) II (DNA directed) polypeptide G
RGD ID: 733857
MGI Page MGI
Description: Predicted to enable single-stranded DNA binding activity; single-stranded RNA binding activity; and translation initiation factor binding activity. Predicted to be involved in regulation of gene expression and transcription initiation from RNA polymerase II promoter. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Predicted to be active in P-body. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; integumental system; and telencephalon. Orthologous to human POLR2G (RNA polymerase II subunit G); PARTICIPATES IN RNA polymerase II transcription pathway; Huntington's disease pathway; purine metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410046K11Rik; A230108L04Rik; C76415; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; RB; RBP7; RNA polymerase II 7-like; RNA polymerase II subunit B7; Rpo; Rpo2-7l
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,770,493 - 8,775,921 (-)NCBIGRCm39mm39
GRCm39 Ensembl198,770,491 - 8,775,941 (-)Ensembl
GRCm38198,793,129 - 8,798,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,793,127 - 8,798,577 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,867,619 - 8,873,047 (-)NCBIGRCm37mm9NCBIm37
MGSCv36198,860,174 - 8,865,602 (-)NCBImm8
Celera198,553,021 - 8,558,449 (-)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:6953443   PMID:8889548   PMID:9256063   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14517553   PMID:14610273   PMID:14681479   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693   PMID:20059953   PMID:20362541   PMID:21873635   PMID:26816005   PMID:32325033  


Genomics

Comparative Map Data
Polr2g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,770,493 - 8,775,921 (-)NCBIGRCm39mm39
GRCm39 Ensembl198,770,491 - 8,775,941 (-)Ensembl
GRCm38198,793,129 - 8,798,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,793,127 - 8,798,577 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,867,619 - 8,873,047 (-)NCBIGRCm37mm9NCBIm37
MGSCv36198,860,174 - 8,865,602 (-)NCBImm8
Celera198,553,021 - 8,558,449 (-)NCBICelera
Cytogenetic Map19ANCBI
POLR2G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1162,761,565 - 62,766,710 (+)EnsemblGRCh38hg38GRCh38
GRCh381162,761,580 - 62,766,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,529,052 - 62,534,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,285,591 - 62,290,757 (+)NCBINCBI36hg18NCBI36
Build 341162,285,590 - 62,290,757NCBI
Celera1159,857,593 - 59,862,769 (+)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,857,889 - 58,863,065 (+)NCBIHuRef
CHM1_11162,412,016 - 62,417,192 (+)NCBICHM1_1
Polr2g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,689,160 - 205,692,537 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1205,689,160 - 205,692,686 (-)Ensembl
Rnor_6.01224,991,250 - 224,998,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,991,222 - 224,994,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,929,423 - 231,936,528 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,462,321 - 211,465,698 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,620,752 - 211,627,860 (-)NCBI
Celera1203,202,089 - 203,205,466 (-)NCBICelera
Cytogenetic Map1q43NCBI
Polr2g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599464,879 - 471,976 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599469,233 - 471,761 (-)NCBIChiLan1.0ChiLan1.0
POLR2G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11161,470,866 - 61,476,073 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,470,866 - 61,476,073 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,116,833 - 58,122,031 (+)NCBIMhudiblu_PPA_v0panPan3
POLR2G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,916,431 - 53,919,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,916,435 - 53,919,549 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,522,261 - 52,530,211 (-)NCBI
ROS_Cfam_1.01854,968,916 - 54,976,918 (-)NCBI
UMICH_Zoey_3.11854,065,288 - 54,073,274 (-)NCBI
UNSW_CanFamBas_1.01853,639,765 - 53,647,770 (-)NCBI
UU_Cfam_GSD_1.01854,436,033 - 54,444,050 (-)NCBI
Polr2g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,409,272 - 10,414,410 (-)NCBI
SpeTri2.0NW_004936581523,018 - 528,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR2G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,003,781 - 9,017,779 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,004,388 - 9,008,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,349,630 - 8,353,856 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR2G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,140,897 - 11,150,879 (-)NCBI
ChlSab1.1 Ensembl111,140,867 - 11,150,882 (-)Ensembl
Vero_WHO_p1.0NW_023666038108,483,625 - 108,488,373 (-)NCBI
Polr2g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249261,228,590 - 1,230,943 (+)NCBI

Position Markers
C76415  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,793,293 - 8,793,375UniSTSGRCm38
MGSCv37198,867,783 - 8,867,865UniSTSGRCm37
Celera198,553,185 - 8,553,267UniSTS
Cytogenetic Map19AUniSTS
Whitehead/MRC_RH1979.49UniSTS
RH125968  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,793,130 - 8,793,364UniSTSGRCm38
MGSCv37198,867,620 - 8,867,854UniSTSGRCm37
Celera198,553,022 - 8,553,256UniSTS
Cytogenetic Map19AUniSTS
Whitehead/MRC_RH193.66UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120278703Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120645286Mouse
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122321310Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19327855120562299Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950147898980461Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:89
Interacting mature miRNAs:101
Transcripts:ENSMUST00000096261
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000096261   ⟹   ENSMUSP00000093980
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,770,491 - 8,775,941 (-)Ensembl
GRCm38.p6 Ensembl198,793,127 - 8,798,577 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235964   ⟹   ENSMUSP00000158073
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,770,549 - 8,775,817 (-)Ensembl
GRCm38.p6 Ensembl198,793,185 - 8,798,453 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236566
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,775,267 - 8,775,889 (-)Ensembl
GRCm38.p6 Ensembl198,797,903 - 8,798,525 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237207
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,771,534 - 8,775,899 (-)Ensembl
GRCm38.p6 Ensembl198,794,170 - 8,798,535 (-)Ensembl
RefSeq Acc Id: NM_026329   ⟹   NP_080605
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39198,770,493 - 8,775,921 (-)NCBI
GRCm38198,793,129 - 8,798,557 (-)ENTREZGENE
MGSCv37198,867,619 - 8,873,047 (-)RGD
Celera198,553,021 - 8,558,449 (-)RGD
cM Map19 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080605   ⟸   NM_026329
- UniProtKB: P62488 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000158073   ⟸   ENSMUST00000235964
RefSeq Acc Id: ENSMUSP00000093980   ⟸   ENSMUST00000096261
Protein Domains
S1 motif

Promoters
RGD ID:13678814
Promoter ID:EPDNEW_M23556
Type:initiation region
Name:Polr2g_1
Description:Mus musculus polymerase II polypeptide G , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38198,798,557 - 8,798,617EPDNEW
RGD ID:6830318
Promoter ID:MM_KWN:26308
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000096261
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36198,872,791 - 8,873,291 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914960 AgrOrtholog
Ensembl Genes ENSMUSG00000003693
  ENSMUSG00000071662 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000093980 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000158073 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000096261 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000235964 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.120 UniProtKB/Swiss-Prot
InterPro NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb7-like_N_sf UniProtKB/Swiss-Prot
  Rpb7-like_N UniProtKB/Swiss-Prot
  S1_dom UniProtKB/Swiss-Prot
  S1_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67710 UniProtKB/Swiss-Prot
MGD MGI:1914960 ENTREZGENE
NCBI Gene 67710 ENTREZGENE
Pfam PF00575 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHS2_Rpb7-N UniProtKB/Swiss-Prot
PhenoGen Polr2g PhenoGen
SMART SM00316 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF88798 UniProtKB/Swiss-Prot
UniProt A0A494BAJ9_MOUSE UniProtKB/TrEMBL
  P62488 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P52433 UniProtKB/Swiss-Prot