Mapk14 (mitogen-activated protein kinase 14) - Rat Genome Database
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Gene: Mapk14 (mitogen-activated protein kinase 14) Mus musculus
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Symbol: Mapk14
Name: mitogen-activated protein kinase 14
RGD ID: 619565
MGI Page MGI
Description: Exhibits MAP kinase activity and NFAT protein binding activity. Involved in several processes, including animal organ development; positive regulation of cell differentiation; and positive regulation of macromolecule metabolic process. Localizes to several cellular components, including glutamatergic synapse; mitochondrion; and spindle pole. Is expressed in several structures, including brain; early conceptus; genitourinary system; heart; and lung. Orthologous to human MAPK14 (mitogen-activated protein kinase 14); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; erythropoietin signaling pathway; INTERACTS WITH (-)-anisomycin; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Crk; Crk1; CSB; Csbp1; CSBP2; cytokine suppressive anti-inflammatory drug binding protein 1; MAP kinase 14; MAP kinase p38 alpha; MAPK 14; MGC102436; mitogen activated protein kinase 14; mitogen-activated protein kinase p38 alpha; Mxi; Mxi2; p3; p38; p38 alpha; p38 MAP kinase alpha; p38 MAPK; p38-; p38-alpha; p38a; p38alpha; p38M; p38MAPK; PRKM14; PRKM15; tRNA synthetase cofactor p38
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,910,243 - 28,967,379 (+)NCBIGRCm39mm39
GRCm381728,691,342 - 28,748,405 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,691,329 - 28,748,406 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,828,287 - 28,885,350 (+)NCBIGRCm37mm9NCBIm37
MGSCv361728,419,034 - 28,475,994 (+)NCBImm8
Celera1729,246,340 - 29,303,175 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(-)-anisomycin  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-lipoic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4',6-tetrachlorobiphenyl  (ISO)
2,4-dinitroiodobenzene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxycyclophosphamide  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-vinylcyclohexene dioxide  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
acetamide  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allopurinol  (ISO)
alvocidib  (ISO)
amifostine  (EXP)
ammonium chloride  (ISO)
aniline  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
asbestos  (ISO)
Asiaticoside  (ISO)
atorvastatin calcium  (EXP,ISO)
atropine  (ISO)
aucubin  (ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-D-glucosamine  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
bromobenzene  (ISO)
bupropion  (ISO)
butylated hydroxyanisole  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
carboplatin  (ISO)
carvedilol  (ISO)
celecoxib  (ISO)
chalcone  (EXP)
chlorogenic acid  (EXP)
chlorpromazine  (ISO)
cholesterol  (ISO)
chromium(6+)  (ISO)
chrysophanol  (ISO)
ciglitazone  (ISO)
cisplatin  (EXP)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
coniferyl aldehyde  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
D-glucitol  (ISO)
D-glucose  (EXP,ISO)
DDT  (ISO)
deoxynivalenol  (EXP,ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (ISO)
dibenziodolium  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (ISO)
Dictamnine  (ISO)
diminazene diaceturate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
doxycycline  (EXP)
ellagic acid  (ISO)
emetine  (ISO)
emodin  (ISO)
endosulfan  (ISO)
ergosterol  (ISO)
esculetin  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (EXP)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP,ISO)
ferric ammonium citrate  (ISO)
fluoxetine  (EXP)
flurbiprofen  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glucose  (EXP,ISO)
haloperidol  (ISO)
halothane  (EXP)
hemin  (ISO)
hexachlorobenzene  (ISO)
hexadecanoic acid  (ISO)
homocysteine  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
ibuprofen  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
iohexol  (ISO)
iopamidol  (ISO)
isoprenaline  (EXP)
KN-93  (ISO)
L-ascorbic acid  (ISO)
L-cysteine  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
limonene  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
lycopene  (ISO)
lycorine  (EXP)
malvidin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
mercury dichloride  (ISO)
mesalamine  (ISO)
metam  (EXP)
metformin  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylmercury(1+)  (ISO)
microcystin-LR  (ISO)
mitomycin C  (ISO)
morphine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-Nitroso-N-methylurethane  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
octanoic acid  (EXP)
oleanolic acid  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenethyl caffeate  (ISO)
phenylephrine  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosalone  (ISO)
phytosphingosine  (ISO)
pirfenidone  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
prostaglandin E2  (EXP,ISO)
protein kinase inhibitor  (ISO)
pterostilbene  (ISO)
pyrazoles  (ISO)
pyrimidines  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
razoxane  (ISO)
reactive oxygen species  (EXP,ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (EXP)
rotenone  (ISO)
rottlerin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
Salinomycin  (ISO)
salubrinal  (ISO)
SB 203580  (EXP,ISO)
scullcapflavone II  (ISO)
serpentine asbestos  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
sorafenib  (ISO)
streptozocin  (EXP,ISO)
sucrose  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
taurodeoxycholic acid  (ISO)
telmisartan  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thalidomide  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trans-chalcone  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trifluoperazine  (EXP,ISO)
trimethylarsine oxide  (ISO)
Triptolide  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tunicamycin  (EXP)
tyrphostin AG 1478  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
wortmannin  (EXP)
Y-27632  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IMP)
apoptotic process  (IEA)
bone development  (IMP)
cartilage condensation  (IMP)
cell morphogenesis  (IGI)
cellular response to DNA damage stimulus  (IDA)
cellular response to ionizing radiation  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to lipoteichoic acid  (ISO)
cellular response to tumor necrosis factor  (IDA)
cellular response to vascular endothelial growth factor stimulus  (ISO)
cellular response to virus  (ISO)
chondrocyte differentiation  (IDA,IMP)
DNA damage checkpoint  (IMP)
fatty acid oxidation  (IMP)
glucose metabolic process  (IMP)
intracellular signal transduction  (IBA,IDA,ISO)
lipopolysaccharide-mediated signaling pathway  (IDA)
MAPK cascade  (IMP)
myoblast differentiation involved in skeletal muscle regeneration  (IMP)
negative regulation of canonical Wnt signaling pathway  (IMP)
negative regulation of hippo signaling  (ISO)
osteoblast differentiation  (IMP)
osteoclast differentiation  (IMP)
p38MAPK cascade  (IDA)
peptidyl-serine phosphorylation  (IDA)
phosphorylation  (IEA,ISO)
placenta development  (IMP)
positive regulation of blood vessel endothelial cell migration  (ISO)
positive regulation of brown fat cell differentiation  (IMP)
positive regulation of cardiac muscle cell proliferation  (IGI)
positive regulation of cyclase activity  (ISO)
positive regulation of erythrocyte differentiation  (IMP,ISO)
positive regulation of gene expression  (IMP,ISO)
positive regulation of glucose import  (IMP)
positive regulation of interleukin-12 production  (ISO)
positive regulation of myoblast differentiation  (IMP)
positive regulation of myoblast fusion  (IMP)
positive regulation of myotube differentiation  (IMP)
positive regulation of protein import into nucleus  (IMP)
positive regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of transcription by RNA polymerase II  (IMP,ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (IDA,IMP,ISO)
regulation of cytokine production involved in inflammatory response  (ISO)
regulation of ossification  (IDA)
regulation of synaptic membrane adhesion  (EXP,IDA,IEP,IMP)
regulation of transcription by RNA polymerase II  (IMP)
regulation of transcription, DNA-templated  (IDA)
response to glucose  (ISO)
response to lipopolysaccharide  (IDA)
response to muramyl dipeptide  (IDA)
response to muscle stretch  (IMP)
signal transduction in response to DNA damage  (ISO)
skeletal muscle tissue development  (IMP)
stress-activated MAPK cascade  (ISO)
stress-induced premature senescence  (ISO)
striated muscle cell differentiation  (IGI)
transmembrane receptor protein serine/threonine kinase signaling pathway  (IGI)
vascular endothelial growth factor receptor signaling pathway  (ISO)

Cellular Component
cytoplasm  (IBA,IDA)
cytosol  (IDA,ISO,TAS)
glutamatergic synapse  (EXP,IDA,IEP,IMP)
mitochondrion  (IDA)
nuclear speck  (ISO)
nucleoplasm  (TAS)
nucleus  (IBA,IDA,ISO)
spindle pole  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal associative learning  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell physiology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal fetal cardiomyocyte morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal liver morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal lung development  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal muscle fiber morphology  (IAGP)
abnormal myoblast differentiation  (IAGP)
abnormal myoblast fusion  (IAGP)
abnormal neuron proliferation  (IAGP)
abnormal placenta development  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal pulmonary alveolus epithelial cell morphology  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal T-helper 1 cell differentiation  (IEA)
abnormal T-helper 1 physiology  (IAGP)
abnormal T-helper 17 cell differentiation  (IEA)
abnormal T-helper 2 cell differentiation  (IEA)
abnormal trophoblast layer morphology  (IAGP)
abnormal tumor incidence  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
absent myocardial trabeculae  (IAGP)
absent placental labyrinth  (IAGP)
anemia  (IAGP)
cardiac fibrosis  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased circulating glucose level  (IAGP)
decreased interferon-alpha secretion  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased myocardial infarction size  (IAGP)
decreased pancreatic beta cell proliferation  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased placental labyrinth size  (IAGP)
decreased spongiotrophoblast size  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IEA)
decreased susceptibility to induced arthritis  (IEA)
decreased T cell proliferation  (IAGP)
decreased trophoblast giant cell number  (IAGP)
decreased tumor incidence  (IAGP)
decreased tumor necrosis factor secretion  (IEA)
decreased width of hypertrophic chondrocyte zone  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged heart  (IAGP)
enlarged lung  (IAGP)
exencephaly  (IAGP)
impaired placental function  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased cell proliferation  (IAGP)
increased double-negative T cell number  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased heart weight  (IAGP)
increased hemolymphoid system tumor incidence  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased interleukin-10 secretion  (IEA)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased lung tumor incidence  (IAGP)
increased myoblast proliferation  (IAGP)
increased pancreatic beta cell proliferation  (IAGP)
increased response of heart to induced stress  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
pale liver  (IAGP)
pale yolk sac  (IAGP)
pallor  (IAGP)
poor circulation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
primary sex reversal  (IAGP)
short femur  (IAGP)
short tibia  (IAGP)
small liver  (IAGP)
small vertebrae  (IAGP)
spina bifida  (IAGP)
thin myocardium  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
1. Caverzasio J, etal., J Bone Miner Res. 2008 Sep;23(9):1389-97. doi: 10.1359/jbmr.080410.
2. Chattopadhyay M, etal., J Neurosci. 2008 Jun 25;28(26):6652-8.
3. Cuenda A and Rousseau S, Biochim Biophys Acta. 2007 Aug;1773(8):1358-75. Epub 2007 Mar 24.
4. Feng A, etal., PLoS One. 2013 Dec 2;8(12):e80997. doi: 10.1371/journal.pone.0080997. eCollection 2013.
5. Feng AW, etal., Fitoterapia. 2011 May 27.
6. Hirai S, etal., Development 2002 Oct;129(19):4483-95.
7. Holasek SS, etal., Brain Res. 2005 May 31;1045(1-2):185-98. Epub 2005 Apr 25.
8. Hu MC, etal., J Biol Chem 1999 Mar 12;274(11):7095-102.
9. Huang J, etal., Chin Med J (Engl). 2010 May 20;123(10):1311-4.
10. Kaiser RA, etal., J Biol Chem. 2004 Apr 9;279(15):15524-30. Epub 2004 Jan 28.
11. Liao P, etal., Proc Natl Acad Sci U S A 2001 Oct 9;98(21):12283-8. Epub 2001 Oct 02.
12. Lim AK, etal., Diabetologia. 2009 Feb;52(2):347-58. Epub 2008 Dec 9.
13. Lu G, etal., J Biol Chem. 2006 Mar 3;281(9):6087-95. Epub 2005 Dec 28.
14. MGD and Homologene mouse data transfer
15. MGD data from the GO Consortium
16. MGD IEA
17. Munoz L, etal., J Neuroinflammation. 2007 Sep 4;4:21.
18. Pipeline to import KEGG annotations from KEGG into RGD
19. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
20. Pipeline to import SMPDB annotations from SMPDB into RGD
21. RGD automated import pipeline
22. RGD automated import pipeline for gene-chemical interactions
23. Ryan J, etal., Lab Invest. 2011 Dec;91(12):1727-38. doi: 10.1038/labinvest.2011.137. Epub 2011 Sep 5.
24. Tamura K, etal., Cell 2000 Jul 21;102(2):221-31.
25. Thandavarayan RA, etal., Am J Physiol Heart Circ Physiol. 2009 Jul 17.
26. Toyama K, etal., Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):616-25. doi: 10.1161/ATVBAHA.113.302440. Epub 2013 Dec 26.
27. Yamauchi T, etal., Nature 2003 Jun 12;423(6941):762-9.
Additional References at PubMed
PMID:1459009   PMID:7839144   PMID:7914033   PMID:8444355   PMID:8449498   PMID:8925912   PMID:9064344   PMID:9122194   PMID:9135144   PMID:9155017   PMID:9806642   PMID:10349636  
PMID:10415025   PMID:10601328   PMID:10629051   PMID:10637276   PMID:10704466   PMID:10797012   PMID:10922068   PMID:10944112   PMID:10949032   PMID:10973481   PMID:11042159   PMID:11062068  
PMID:11076861   PMID:11217851   PMID:11279073   PMID:11490018   PMID:11711538   PMID:11744690   PMID:11756692   PMID:11792567   PMID:11792570   PMID:11792706   PMID:11796722   PMID:11880364  
PMID:11884367   PMID:11937560   PMID:11948180   PMID:11960370   PMID:11988087   PMID:11997522   PMID:12015964   PMID:12021326   PMID:12032842   PMID:12055252   PMID:12058061   PMID:12060739  
PMID:12068299   PMID:12082638   PMID:12085353   PMID:12096337   PMID:12112010   PMID:12138127   PMID:12149242   PMID:12175822   PMID:12202685   PMID:12232043   PMID:12242275   PMID:12244175  
PMID:12359721   PMID:12359878   PMID:12369781   PMID:12370805   PMID:12374793   PMID:12376107   PMID:12384504   PMID:12386165   PMID:12391245   PMID:12391307   PMID:12393706   PMID:12393894  
PMID:12414118   PMID:12421981   PMID:12425949   PMID:12466851   PMID:12477932   PMID:12478662   PMID:12482988   PMID:12506138   PMID:12520002   PMID:12581156   PMID:12583813   PMID:12589053  
PMID:12593847   PMID:12609991   PMID:12612065   PMID:12637498   PMID:12695487   PMID:12697715   PMID:12717433   PMID:12719557   PMID:12748288   PMID:12750397   PMID:12759445   PMID:12788225  
PMID:12805214   PMID:12808090   PMID:12819782   PMID:12855555   PMID:12872135   PMID:12893778   PMID:12897243   PMID:12904583   PMID:12937170   PMID:12947324   PMID:12951358   PMID:12960069  
PMID:14499647   PMID:14561730   PMID:14563843   PMID:14578350   PMID:14585994   PMID:14592977   PMID:14593000   PMID:14606520   PMID:14610273   PMID:14617800   PMID:14622137   PMID:14626445  
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PMID:29176575   PMID:29247325   PMID:29258820   PMID:29268268   PMID:29273814   PMID:29290625   PMID:29321139   PMID:29357353   PMID:29411501   PMID:29416029   PMID:29495001   PMID:29504713  
PMID:29512760   PMID:29535261   PMID:29550588   PMID:29567616   PMID:29601781   PMID:29638158   PMID:29670085   PMID:29750781   PMID:29752472   PMID:29805078   PMID:29852132   PMID:29899110  
PMID:29899409   PMID:29899565   PMID:29907597   PMID:29979672   PMID:30022044   PMID:30066835   PMID:30135318   PMID:30152849   PMID:30160360   PMID:30195496   PMID:30246940   PMID:30250211  
PMID:30268758   PMID:30301786   PMID:30333137   PMID:30413887   PMID:30466882   PMID:30503674   PMID:30541887   PMID:30548297   PMID:30562644   PMID:30677408   PMID:30681755   PMID:30718368  
PMID:30735722   PMID:30771750   PMID:30846722   PMID:30898653   PMID:30905780   PMID:30908891   PMID:30938680   PMID:30940732   PMID:30999647   PMID:31023527   PMID:31080114   PMID:31173941  
PMID:31176685   PMID:31241461   PMID:31273206   PMID:31290162   PMID:31295066   PMID:31296856   PMID:31337738   PMID:31387001   PMID:31410202   PMID:31476692   PMID:31503548   PMID:31505169  
PMID:31545558   PMID:31560167   PMID:31581792   PMID:31589123   PMID:31601995   PMID:31673920   PMID:31700003   PMID:31727012   PMID:31896747   PMID:31969449   PMID:32022930   PMID:32337281  
PMID:32351999   PMID:32413093   PMID:32464258   PMID:32662771   PMID:32780722  


Genomics

Comparative Map Data
Mapk14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,910,243 - 28,967,379 (+)NCBIGRCm39mm39
GRCm381728,691,342 - 28,748,405 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,691,329 - 28,748,406 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,828,287 - 28,885,350 (+)NCBIGRCm37mm9NCBIm37
MGSCv361728,419,034 - 28,475,994 (+)NCBImm8
Celera1729,246,340 - 29,303,175 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.85NCBI
MAPK14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl636,027,677 - 36,111,236 (+)EnsemblGRCh38hg38GRCh38
GRCh38636,027,711 - 36,122,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37635,995,585 - 36,079,013 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37635,995,412 - 36,079,013 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,103,551 - 36,186,513 (+)NCBINCBI36hg18NCBI36
Build 34636,103,550 - 36,186,513NCBI
Celera637,550,014 - 37,633,560 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef635,715,466 - 35,798,847 (+)NCBIHuRef
CHM1_1635,997,235 - 36,080,771 (+)NCBICHM1_1
Mapk14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2206,749,646 - 6,810,590 (+)NCBI
Rnor_6.0 Ensembl205,933,303 - 5,995,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0205,933,290 - 5,995,137 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,968,528 - 8,028,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,939,249 - 7,000,378 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1206,939,475 - 7,000,605 (+)NCBI
Celera208,305,853 - 8,366,371 (+)NCBICelera
Cytogenetic Map20p12NCBI
Mapk14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554373,838,232 - 3,884,083 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554373,836,331 - 3,884,083 (+)NCBIChiLan1.0ChiLan1.0
MAPK14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1636,788,233 - 36,871,114 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,788,233 - 36,871,114 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0635,586,847 - 35,683,041 (+)NCBIMhudiblu_PPA_v0panPan3
MAPK14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl125,146,037 - 5,220,603 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1125,145,647 - 5,221,558 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mapk14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647623,237,762 - 23,310,211 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,790,104 - 31,862,038 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,791,398 - 31,861,544 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,725,706 - 36,795,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAPK14
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11736,012,164 - 36,095,542 (-)NCBI
ChlSab1.1 Ensembl1736,014,454 - 36,095,138 (-)Ensembl
Mapk14
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475421,528,121 - 21,598,064 (-)NCBI

Position Markers
10.MMHAP76FRD7.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,744,409 - 28,744,585UniSTSGRCm38
MGSCv371728,881,354 - 28,881,530UniSTSGRCm37
Celera1729,299,179 - 29,299,355UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead_YAC17 UniSTS
U10871  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381728,746,452 - 28,746,626UniSTSGRCm38
MGSCv371728,883,397 - 28,883,571UniSTSGRCm37
Celera1729,301,222 - 29,301,396UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead_YAC17 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17128979566Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17128979566Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17128979566Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17130809908Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17765701129268449Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171661519333600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
12903990Opfaq5_mopen field activity QTL 5 (mouse)172573195128773124Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
12904013Cfq12_mconditioned fear QTL 12 (mouse)172660980730445981Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172765914543574223Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir200bmmu-miR-200b-3pMirtarbaseexternal_infoMicroarray//qRT-PCRNon-Functional MTI (Weak)22101765
Mir17mmu-miR-17-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)19536157
Mir200ammu-miR-200a-3pOncomiRDBexternal_infoNANA22101765
Mir124a-2mmu-miR-124-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18619591
Mir124a-2mmu-miR-124-3pMirtarbaseexternal_infoWestern blotFunctional MTI15806104
Mir141mmu-miR-141-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI22101765
Mir124a-2mmu-miR-124-3pTarbaseexternal_infoOtherPOSITIVE
Mir141mmu-miR-141-3pOncomiRDBexternal_infoNANA22101765
Mir200cmmu-miR-200c-3pMirtarbaseexternal_infoMicroarray//qRT-PCRNon-Functional MTI (Weak)22101765
Mir106bmmu-miR-106b-5pTarbaseexternal_infoReporter GenePOSITIVE
Mir106bmmu-miR-106b-5pTarbaseexternal_infoWesternblitPOSITIVE
Mir106bmmu-miR-106b-5pTarbaseexternal_infoOtherPOSITIVE

Predicted Target Of
Summary Value
Count of predictions:3906
Count of miRNA genes:668
Interacting mature miRNAs:831
Transcripts:ENSMUST00000004990, ENSMUST00000062694, ENSMUST00000114752, ENSMUST00000114754, ENSMUST00000114758, ENSMUST00000124886, ENSMUST00000151613
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001168508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC170998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF128892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF195850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI132714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX568915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D83073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JD591567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U10871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W66694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000004990   ⟹   ENSMUSP00000004990
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,329 - 28,748,406 (+)Ensembl
RefSeq Acc Id: ENSMUST00000062694   ⟹   ENSMUSP00000061958
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,342 - 28,748,405 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114752   ⟹   ENSMUSP00000110400
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,692,568 - 28,748,404 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114754   ⟹   ENSMUSP00000110402
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,342 - 28,748,404 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114758   ⟹   ENSMUSP00000110406
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,445 - 28,741,164 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124886   ⟹   ENSMUSP00000116914
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,440 - 28,728,975 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,741,619 - 28,746,357 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233095
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,728,407 - 28,745,061 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233250   ⟹   ENSMUSP00000156692
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,740 - 28,746,400 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233811   ⟹   ENSMUSP00000156603
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1728,691,445 - 28,748,405 (+)Ensembl
RefSeq Acc Id: NM_001168508   ⟹   NP_001161980
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,910,316 - 28,967,379 (+)NCBI
GRCm381728,691,342 - 28,748,405 (+)NCBI
MGSCv371728,828,287 - 28,885,350 (+)RGD
Celera1729,246,340 - 29,303,175 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001168513   ⟹   NP_001161985
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,911,542 - 28,967,379 (+)NCBI
GRCm381728,692,568 - 28,748,405 (+)NCBI
MGSCv371728,828,287 - 28,885,350 (+)RGD
Celera1729,246,340 - 29,303,175 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001168514   ⟹   NP_001161986
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,910,316 - 28,967,379 (+)NCBI
GRCm381728,691,342 - 28,748,405 (+)NCBI
MGSCv371728,828,287 - 28,885,350 (+)RGD
Celera1729,246,340 - 29,303,175 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357724   ⟹   NP_001344653
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,911,542 - 28,967,379 (+)NCBI
GRCm381728,692,568 - 28,748,405 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011951   ⟹   NP_036081
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,910,316 - 28,967,379 (+)NCBI
GRCm381728,691,342 - 28,748,405 (+)NCBI
MGSCv371728,828,287 - 28,885,350 (+)RGD
Celera1729,246,340 - 29,303,175 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_004939533
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391728,910,243 - 28,967,379 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036081   ⟸   NM_011951
- Peptide Label: isoform 1
- UniProtKB: P47811 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001161980   ⟸   NM_001168508
- Peptide Label: isoform 2
- UniProtKB: P47811 (UniProtKB/Swiss-Prot),   Q5U421 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001161986   ⟸   NM_001168514
- Peptide Label: isoform 3
- UniProtKB: P47811 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001161985   ⟸   NM_001168513
- Peptide Label: isoform 3
- UniProtKB: P47811 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001344653   ⟸   NM_001357724
- Peptide Label: isoform 3
RefSeq Acc Id: ENSMUSP00000116914   ⟸   ENSMUST00000124886
RefSeq Acc Id: ENSMUSP00000156692   ⟸   ENSMUST00000233250
RefSeq Acc Id: ENSMUSP00000061958   ⟸   ENSMUST00000062694
RefSeq Acc Id: ENSMUSP00000156603   ⟸   ENSMUST00000233811
RefSeq Acc Id: ENSMUSP00000110406   ⟸   ENSMUST00000114758
RefSeq Acc Id: ENSMUSP00000110402   ⟸   ENSMUST00000114754
RefSeq Acc Id: ENSMUSP00000110400   ⟸   ENSMUST00000114752
RefSeq Acc Id: ENSMUSP00000004990   ⟸   ENSMUST00000004990
Protein Domains
Protein kinase

Promoters
RGD ID:13675374
Promoter ID:EPDNEW_M21836
Type:initiation region
Name:Mapk14_1
Description:Mus musculus mitogen-activated protein kinase 14 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21837  EPDNEW_M21838  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381728,691,430 - 28,691,490EPDNEW
RGD ID:13675376
Promoter ID:EPDNEW_M21837
Type:initiation region
Name:Mapk14_3
Description:Mus musculus mitogen-activated protein kinase 14 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21836  EPDNEW_M21838  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381728,692,598 - 28,692,658EPDNEW
RGD ID:13675378
Promoter ID:EPDNEW_M21838
Type:single initiation site
Name:Mapk14_2
Description:Mus musculus mitogen-activated protein kinase 14 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21836  EPDNEW_M21837  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381728,697,378 - 28,697,438EPDNEW
RGD ID:6828326
Promoter ID:MM_KWN:22879
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000114758,   NM_001168514,   NM_011951_MAPK14,   OTTMUST00000047776,   UC008BRL.1,   UC008BRM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361728,828,114 - 28,828,614 (+)MPROMDB
RGD ID:6828325
Promoter ID:MM_KWN:22880
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Kidney,   Lung,   MEF_B6
Transcripts:UC008BRN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361728,828,981 - 28,829,582 (+)MPROMDB
RGD ID:6828324
Promoter ID:MM_KWN:22883
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Kidney,   Liver
Transcripts:OTTMUST00000047777
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361728,877,581 - 28,878,482 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346865 AgrOrtholog
Ensembl Genes ENSMUSG00000053436 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000004990 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000061958 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110400 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110402 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110406 UniProtKB/Swiss-Prot
  ENSMUSP00000116914 UniProtKB/TrEMBL
  ENSMUSP00000156603 UniProtKB/TrEMBL
  ENSMUSP00000156692 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000004990 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000062694 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114752 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114754 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114758 UniProtKB/Swiss-Prot
  ENSMUST00000124886 UniProtKB/TrEMBL
  ENSMUST00000233250 UniProtKB/TrEMBL
  ENSMUST00000233811 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAP_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAPK_p38-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p38alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26416 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1346865 ENTREZGENE
NCBI Gene 26416 ENTREZGENE
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mapk14 PhenoGen
PRINTS P38MAPKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MAPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2WAZ7_MOUSE UniProtKB/TrEMBL
  A0A3B2WB60_MOUSE UniProtKB/TrEMBL
  B2KF34_MOUSE UniProtKB/TrEMBL
  MK14_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U421 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2KF37 UniProtKB/Swiss-Prot
  B2KF38 UniProtKB/Swiss-Prot
  O08666 UniProtKB/Swiss-Prot
  Q3U6R5 UniProtKB/Swiss-Prot
  Q3UZS3 UniProtKB/Swiss-Prot
  Q8C289 UniProtKB/Swiss-Prot
  Q9JLV8 UniProtKB/Swiss-Prot
  Q9QZ80 UniProtKB/Swiss-Prot