Slc22a1 (solute carrier family 22 (organic cation transporter), member 1) - Rat Genome Database

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Gene: Slc22a1 (solute carrier family 22 (organic cation transporter), member 1) Mus musculus
Analyze
Symbol: Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
RGD ID: 737278
MGI Page MGI
Description: Enables several functions, including organic cation transmembrane transporter activity; pyrimidine nucleoside transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in several processes, including acyl carnitine transmembrane transport; monoamine transport; and organic cation transport. Acts upstream of or within monoatomic cation transport; organic cation transport; and transmembrane transport. Located in apical plasma membrane and basolateral plasma membrane. Is expressed in several structures, including adrenal gland; liver; mammary gland; metanephros; and nasal cavity mucosa. Orthologous to human SLC22A1 (solute carrier family 22 member 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Lx; Lx1; MGC14019; mOCT1; Oct; Oct1; Or; Orc; Orct; Orct1; organic cation transporter 1; solute carrier family 22 member 1; solute carrier family 22, member 1
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,867,761 - 12,894,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,867,756 - 12,894,716 (-)EnsemblGRCm39 Ensembl
GRCm381712,648,874 - 12,675,838 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,648,869 - 12,675,829 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,841,740 - 12,868,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,492,232 - 12,519,196 (-)NCBIMGSCv36mm8
Celera1712,680,587 - 12,707,864 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(+)-schisandrin B  (ISO)
(S)-nicotine  (ISO)
1,1'-diethyl-2,2'-cyanine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-methylnicotinamide  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine  (ISO)
3-[2-(ethylamino)-1-hydroxyethyl]phenol  (ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol  (ISO)
abacavir  (ISO)
acetamide  (ISO)
acetamiprid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allopurinol  (EXP,ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
angelicin  (EXP)
aristolochic acid A  (ISO)
aristolochic acids  (ISO)
atazanavir sulfate  (ISO)
atenolol  (ISO)
atorvastatin calcium  (EXP,ISO)
atropine  (ISO)
bacitracin  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-carboline  (ISO)
beta-naphthoflavone  (ISO)
biphenyl-4-amine  (ISO)
bisoprolol  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (ISO)
carvedilol  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlordecone  (EXP)
chloroquine  (ISO)
chlorphenamine  (ISO)
cimetidine  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dichlorine  (ISO)
diclofenac  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
digoxin  (ISO)
diltiazem  (ISO)
diosmetin  (ISO)
diphenhydramine  (ISO)
disopyramide  (ISO)
dopamine  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethidium  (EXP,ISO)
famotidine  (ISO)
fenthion  (EXP)
finasteride  (ISO)
flecainide  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
fonofos  (ISO)
fructose  (ISO)
fumonisin B1  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
graphite  (ISO)
harman  (ISO)
heptachlor  (ISO)
hyperforin  (ISO)
ibuprofen  (ISO)
imidacloprid  (ISO)
imipramine  (ISO)
imperatorin  (EXP)
indometacin  (ISO)
ipratropium  (ISO)
isoimperatorin  (EXP)
ketoprofen  (ISO)
L-ethionine  (ISO)
lamivudine  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (EXP)
mefenamic acid  (ISO)
mefloquine  (ISO)
MeIQ  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methoxsalen  (EXP)
metoprolol  (ISO)
molsidomine  (ISO)
monocrotaline  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nadolol  (ISO)
nefazodone  (ISO)
nicotine  (ISO)
nifedipine  (ISO)
nimesulide  (ISO)
nitenpyram  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
omeprazole  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (EXP,ISO)
Phenoxybenzamine  (ISO)
phenylephrine  (ISO)
PhIP  (ISO)
pirinixic acid  (ISO)
Potassium 2,6-dihydroxytriazinecarboxylate  (EXP)
potassium dichromate  (EXP)
prazosin  (ISO)
probenecid  (EXP)
prochloraz  (EXP)
progesterone  (ISO)
propafenone  (ISO)
propranolol  (ISO)
psoralen  (EXP)
pyrimethamine  (ISO)
quercetin  (EXP,ISO)
quinidine  (ISO)
quinine  (ISO)
ranitidine  (ISO)
resveratrol  (EXP)
Retrorsine  (ISO)
rifampicin  (ISO)
rutin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
senecionine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
soybean oil  (ISO)
spironolactone  (ISO)
streptozocin  (ISO)
sulindac  (ISO)
Sunset Yellow FCF  (ISO)
synephrine  (ISO)
talinolol  (ISO)
tartrazine  (ISO)
terbufos  (ISO)
tetrabutylammonium  (ISO)
tetrachloromethane  (EXP,ISO)
tetraethylammonium  (ISO)
tetrahydropalmatine  (ISO)
tetrapentylammonium  (ISO)
thiacloprid  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trans-piceid  (EXP)
trichloroethene  (ISO)
trimethoprim  (ISO)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
trospium chloride  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
verapamil  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Metformin pathways: pharmacokinetics and pharmacodynamics. Gong L, etal., Pharmacogenet Genomics. 2012 Nov;22(11):820-7. doi: 10.1097/FPC.0b013e3283559b22.
2. Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia. Heemskerk S, etal., Eur J Pharmacol. 2008 Apr 28;584(2-3):390-7. doi: 10.1016/j.ejphar.2008.02.006. Epub 2008 Feb 12.
3. Quercetin regulates organic ion transporter and uromodulin expression and improves renal function in hyperuricemic mice. Hu QH, etal., Eur J Nutr. 2012 Aug;51(5):593-606. doi: 10.1007/s00394-011-0243-y. Epub 2011 Sep 10.
4. Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis. Jin HE, etal., Pharm Res. 2009 Mar;26(3):549-59. doi: 10.1007/s11095-008-9770-5. Epub 2008 Nov 11.
5. Elevated systemic elimination of cimetidine in rats with acute biliary obstruction: the role of renal organic cation transporter OCT2. Kurata T, etal., Drug Metab Pharmacokinet. 2010;25(4):328-34.
6. Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. Lips KS, etal., Life Sci. 2007 May 30;80(24-25):2263-9. Epub 2007 Jan 23.
7. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Nitric oxide-induced regulation of renal organic cation transport after renal ischemia-reperfusion injury. Schneider R, etal., Am J Physiol Renal Physiol. 2011 Nov;301(5):F997-F1004. doi: 10.1152/ajprenal.00264.2011. Epub 2011 Aug 10.
16. Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury. Ulu R, etal., Food Chem Toxicol. 2012 May;50(5):1675-9. doi: 10.1016/j.fct.2012.02.082. Epub 2012 Mar 3.
17. Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice. Wang CP, etal., Planta Med. 2011 May;77(8):786-94. doi: 10.1055/s-0030-1250599. Epub 2010 Dec 10.
18. Renal tumours in a Tsc1(+)/(-) mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin. Yang J, etal., Eur J Cancer. 2013 Apr;49(6):1479-90. doi: 10.1016/j.ejca.2012.10.027. Epub 2012 Dec 7.
Additional References at PubMed
PMID:8854860   PMID:9268631   PMID:9605850   PMID:9933568   PMID:10051314   PMID:10216142   PMID:10751225   PMID:11208732   PMID:11222742   PMID:11463829   PMID:11562346   PMID:11641723  
PMID:11907091   PMID:12123738   PMID:12130709   PMID:12151092   PMID:12176030   PMID:12395324   PMID:12477932   PMID:12752447   PMID:14560032   PMID:15262984   PMID:15369770   PMID:15388790  
PMID:15458920   PMID:15613485   PMID:16166650   PMID:16204191   PMID:16608531   PMID:16897347   PMID:16965262   PMID:17476361   PMID:17609683   PMID:19266165   PMID:19521566   PMID:20032962  
PMID:20110413   PMID:20371711   PMID:20477935   PMID:20876643   PMID:21267068   PMID:21873635   PMID:22300281   PMID:22454430   PMID:22684023   PMID:23458604   PMID:23467089   PMID:23680637  
PMID:24233562   PMID:24961373   PMID:25848011   PMID:25918552   PMID:26979622   PMID:28942964   PMID:29659562   PMID:32325033   PMID:32961667   PMID:33375004   PMID:33658943   PMID:34040533  
PMID:35469921   PMID:35951416  


Genomics

Comparative Map Data
Slc22a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,867,761 - 12,894,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,867,756 - 12,894,716 (-)EnsemblGRCm39 Ensembl
GRCm381712,648,874 - 12,675,838 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,648,869 - 12,675,829 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,841,740 - 12,868,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,492,232 - 12,519,196 (-)NCBIMGSCv36mm8
Celera1712,680,587 - 12,707,864 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.63NCBI
SLC22A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386160,121,815 - 160,158,718 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6160,121,815 - 160,158,718 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,542,847 - 160,579,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,462,853 - 160,499,740 (+)NCBINCBI36Build 36hg18NCBI36
Build 346160,513,273 - 160,550,159NCBI
Celera6161,188,634 - 161,224,539 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6158,013,550 - 158,049,540 (+)NCBIHuRef
CHM1_16160,805,108 - 160,841,995 (+)NCBICHM1_1
T2T-CHM13v2.06161,367,910 - 161,404,908 (+)NCBIT2T-CHM13v2.0
Slc22a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2148,076,657 - 48,103,679 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,076,666 - 48,103,678 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,768,287 - 48,795,288 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0154,754,091 - 54,781,071 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0148,843,810 - 48,870,799 (+)NCBIRnor_WKY
Rnor_6.0148,273,639 - 48,300,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,273,611 - 48,300,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,452,604 - 51,479,610 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,351,239 - 42,378,295 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,354,183 - 42,381,239 (+)NCBI
Celera143,876,335 - 43,903,290 (+)NCBICelera
Cytogenetic Map1q11NCBI
SLC22A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16163,014,522 - 163,054,818 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6163,014,663 - 163,054,681 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06158,004,545 - 158,046,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC22A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,268,978 - 49,296,522 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,109,085 - 50,138,635 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,451,887 - 49,481,466 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,451,182 - 49,482,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,334,247 - 49,363,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,205,883 - 49,235,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,820,796 - 49,850,348 (+)NCBIUU_Cfam_GSD_1.0
Slc22a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,281,749 - 144,305,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,534,095 - 11,556,745 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648911,534,095 - 11,556,759 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC22A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,340,126 - 7,365,520 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,340,442 - 7,365,543 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,139,435 - 9,164,369 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC22A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,744,600 - 87,780,846 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,745,023 - 87,781,073 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604060,132,123 - 60,167,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:109
Interacting mature miRNAs:115
Transcripts:ENSMUST00000024596
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse

Markers in Region
U38652  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,648,891 - 12,648,998UniSTSGRCm38
MGSCv371712,841,757 - 12,841,864UniSTSGRCm37
Celera1712,680,604 - 12,680,711UniSTS
Cytogenetic Map17A1UniSTS
cM Map177.34UniSTS
Whitehead/MRC_RH17216.99UniSTS
Slc22a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A1UniSTS
cM Map177.34UniSTS
cM Map177.34UniSTS
D17Jcs63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,677,353 - 12,677,526UniSTSGRCm38
MGSCv371712,870,219 - 12,870,392UniSTSGRCm37
Cytogenetic Map17A1UniSTS
cM Map17 UniSTS
Slc22a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A1UniSTS
cM Map177.34UniSTS
Slc22a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A1UniSTS
cM Map177.34UniSTS
Slc22a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000024596   ⟹   ENSMUSP00000024596
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,867,761 - 12,894,716 (-)Ensembl
GRCm38.p6 Ensembl1712,648,874 - 12,675,829 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233601
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,867,767 - 12,871,595 (-)Ensembl
GRCm38.p6 Ensembl1712,648,880 - 12,652,708 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233691   ⟹   ENSMUSP00000156652
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,867,756 - 12,894,583 (-)Ensembl
GRCm38.p6 Ensembl1712,648,869 - 12,675,696 (-)Ensembl
RefSeq Acc Id: NM_009202   ⟹   NP_033228
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391712,867,761 - 12,894,725 (-)NCBI
GRCm381712,648,874 - 12,675,838 (-)ENTREZGENE
MGSCv371712,841,740 - 12,868,704 (-)RGD
Celera1712,680,587 - 12,707,864 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033228   ⟸   NM_009202
- UniProtKB: Q9R1Q4 (UniProtKB/Swiss-Prot),   O08966 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000156652   ⟸   ENSMUST00000233691
RefSeq Acc Id: ENSMUSP00000024596   ⟸   ENSMUST00000024596

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08966-F1-model_v2 AlphaFold O08966 1-556 view protein structure

Promoters
RGD ID:13674752
Promoter ID:EPDNEW_M21525
Type:initiation region
Name:Slc22a1_1
Description:Mus musculus solute carrier family 22 , member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381712,675,707 - 12,675,767EPDNEW
RGD ID:6828679
Promoter ID:MM_KWN:22117
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:NM_009202
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361712,868,364 - 12,868,864 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108111 AgrOrtholog
Ensembl Genes ENSMUSG00000023829 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000024596 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000156652.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024596 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000233691.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot
InterPro MFS_dom UniProtKB/Swiss-Prot
  MFS_sugar_transport-like UniProtKB/Swiss-Prot
  MFS_trans_sf UniProtKB/Swiss-Prot
  Orgcat_transp/SVOP UniProtKB/Swiss-Prot
  Sugar_transporter_CS UniProtKB/Swiss-Prot
KEGG Report mmu:20517 UniProtKB/Swiss-Prot
MGD MGI:108111 ENTREZGENE
NCBI Gene 20517 ENTREZGENE
Pfam Sugar_tr UniProtKB/Swiss-Prot
PharmGKB SLC22A1 RGD
PhenoGen Slc22a1 PhenoGen
PROSITE MFS UniProtKB/Swiss-Prot
  SUGAR_TRANSPORT_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot
TIGRFAMs 2A0119 UniProtKB/Swiss-Prot
UniProt A0A3B2WB35_MOUSE UniProtKB/TrEMBL
  O08966 ENTREZGENE
  Q9R1Q4 ENTREZGENE
  S22A1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9R1Q4 UniProtKB/Swiss-Prot